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Vaccination: Pneomococcal Vaccine
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Total 3041 results found since Jan 2013.
Etiology of Acute Infectious Meningitis and Meningoencephalitis in Karachi, Pakistan: Retrospective Observational Study from a Tertiary Care Center
We report a broad range of pathogens causing ME in southern Pakistan and show a high burden of preventable illness. Synergistic actions to improve diagnostic strategies, increase vaccinations, and introduce measures to reduce water-borne and vector-borne diseases are required to reduce the ME burden in Pakistan and prevent future outbreaks.PMID:37460090 | DOI:10.4269/ajtmh.23-0182
Source: The American Journal of Tropical Medicine and Hygiene - July 17, 2023 Category: Tropical Medicine Authors: Sadia Shakoor Tazeen Fatima Fatima Mir Asima Shahid Najma Shaheen Erum Khan Bushra Jamil Source Type: research
TWiV 1026: Debunking RFK Jr. ’s vaccine funk with Dan Wilson
Dan Wilson returns to TWiV to debunk vaccine misinformation by RFK Jr. during his recent appearance on the Joe Rogan Experience. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Dan Wilson Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Joe Rogan’s worst misinformation yet, with RFK Jr. (YouTube) Every first vaccine has been tested in placebo-controlled trials before going to market. Polio Measles HPV COVID-19 HepB Haemophilus influenzae B Pertussis Diphtheria Tetanus...
Source: This Week in Virology - MP3 Edition - July 16, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Impact of COVID vaccine and comorbidities in patients receiving casirivimab-imdevimab monoclonal antibody during SARS-CoV-2 B.1.617.2 (Delta) surge: A real-world study
CONCLUSION: COVID vaccination status and comorbidities are significant predictors of outcomes after casirivimab-imdevimab treatment. Despite having higher comorbidities, patients who were fully vaccinated at the time of casirivimab-imdevimab infusion had a lower length of hospitalization and reduced 28-day COVID ED visits or hospitalizations. Future trials should also compare outcomes based on the patient's vaccination status.PMID:37451874 | DOI:10.1016/j.vaccine.2023.07.011
Source: Vaccine - July 14, 2023 Category: Allergy & Immunology Authors: Pankaj Agrawal Dushyant Damania Attila Cseh John Grab Laura Strom Brianna Frank Dhruv Patel Griffin Clyatt Source Type: research
An in-depth appraisal of clinico-biochemical and radiological findings of COVID-19 patients during the COVID-19 pandemic in a dedicated COVID Care Hospital in Eastern India and its outcome in relation to the COVAXIN vaccination status: A 2-year study
CONCLUSION: Immune dysregulation plays a central role in the pathogenesis of the manifestations. Vaccine-induced protection and the induction of herd immunity played a proactive role in the waning of the severity of clinical presentations.PMID:37448914 | PMC:PMC10336931 | DOI:10.4103/jfmpc.jfmpc_1853_22
Source: Primary Care - July 14, 2023 Category: Primary Care Authors: C Mohan Rao Amrut Kumar Mohapatra Aswini Kumar Patnaik Prem S Panda Prasanta Ranjan Behera Source Type: research
A Q fever outbreak among visitors to a natural cave, Bizkaia, Spain, December 2020 to October 2021
We describe a large Q fever outbreak reported in Spain, including 108 cases, 53 with pneumonia and 27 requiring hospitalisations. The first cases were detected in February 2021 among rock climbers visiting a cave in Bizkaia, and the last case was detected in October 2021. Most cases were notified after the Easter holiday (April-May 2021). More males (63.9%) than females (36.1%) were infected (median ages: 42 (1-68) and 39 years (6-61), respectively). We detected Coxiella burnetii by PCR in faecal, dust and/or aerosol samples taken inside the cave in March 2021, and in dust and aerosol samples collected between March 2021 a...
Source: Euro Surveill - July 13, 2023 Category: Infectious Diseases Authors: Ana Hurtado Ion I Zendoia Eva Alonso Xabier Beraza Joseba Bidaurrazaga Blanca Ocabo I ñaki Arrazola Aitor Cevidanes Jes ús F Barandika Ana L Garc ía-Pérez Source Type: research
B cell-intrinsic TLR7 signaling is required for neutralizing antibody responses to SARS-CoV-2 and pathogen-like COVID-19 vaccines
Eur J Immunol. 2023 Jul 12:e2350437. doi: 10.1002/eji.202350437. Online ahead of print.ABSTRACTToll-like receptor 7 (TLR7) triggers antiviral immune responses through its capacity to recognize single-stranded RNA. TLR7 loss-of-function mutants are associated with life-threatening pneumonia in severe COVID-19 patients. Whereas TLR7-driven innate induction of type I IFN appears central to control SARS-CoV2 virus spreading during the first days of infection, the impact of TLR7-deficiency on adaptive B-cell immunity is less clear. In the present study, we examined the role of TLR7 in the adaptive B cells response to various pa...
Source: European Journal of Immunology - July 13, 2023 Category: Allergy & Immunology Authors: Charles-Henry Miquel Flora Abbas Claire Cenac Charlotte Foret-Lucas Chang Guo Mariette Ducatez Etienne Joly Baidong Hou Jean-Charles Gu éry Source Type: research
Position statement on infection screening, prophylaxis, and vaccination in pediatric patients with rheumatic diseases and immunosuppressive therapies, part 2: infection prophylaxis
Conclusion: Based on current evidence and a Delphi process, we provided consensus and updated recommendations on prophylaxis and treatment of infections to guide those caring for pediatric rheumatology patients. What is Known: •Data largely derived from adults find that infectious diseases and related complications are a major cause of morbidity and mortality in patients with immune-mediated rheumatic diseases. •It is crucial to be aware of the preventive measures that should be implemented to prevent these infections in children, although most guidelines are often extrapolated from adult cases. What is New: •In the ...
Source: Herpes - July 13, 2023 Category: Infectious Diseases Authors: Daniel Clemente Garulo Esmeralda N úñez-Cuadros Marisol Camacho Lovillo Joan Calzada-Hern ández Sara Guill én Martín Laura Fern ández Silveira Mar ía José Lirola Cruz Alfredo Tagarro Rosa Mar ía Alcobendas Rueda Agust ín López López Miren Satr Source Type: research
B cell-intrinsic TLR7 signaling is required for neutralizing antibody responses to SARS-CoV-2 and pathogen-like COVID-19 vaccines
Eur J Immunol. 2023 Jul 12:e2350437. doi: 10.1002/eji.202350437. Online ahead of print.ABSTRACTToll-like receptor 7 (TLR7) triggers antiviral immune responses through its capacity to recognize single-stranded RNA. TLR7 loss-of-function mutants are associated with life-threatening pneumonia in severe COVID-19 patients. Whereas TLR7-driven innate induction of type I IFN appears central to control SARS-CoV2 virus spreading during the first days of infection, the impact of TLR7-deficiency on adaptive B-cell immunity is less clear. In the present study, we examined the role of TLR7 in the adaptive B cells response to various pa...
Source: European Journal of Immunology - July 13, 2023 Category: Allergy & Immunology Authors: Charles-Henry Miquel Flora Abbas Claire Cenac Charlotte Foret-Lucas Chang Guo Mariette Ducatez Etienne Joly Baidong Hou Jean-Charles Gu éry Source Type: research
20 ‑Valent Pneumococcal Conjugate Vaccine: Pediatric First Approval
This article summarizes the milestones in the development of PCV20 leading to this first pediatric approval for active immunization for the prevention of IPD and otitis media caused by S. pneumoniae.PMID:37440125 | DOI:10.1007/s40272-023-00584-9
Source: Paediatric Drugs - July 13, 2023 Category: Pediatrics Authors: Matt Shirley Source Type: research
A Q fever outbreak among visitors to a natural cave, Bizkaia, Spain, December 2020 to October 2021
We describe a large Q fever outbreak reported in Spain, including 108 cases, 53 with pneumonia and 27 requiring hospitalisations. The first cases were detected in February 2021 among rock climbers visiting a cave in Bizkaia, and the last case was detected in October 2021. Most cases were notified after the Easter holiday (April-May 2021). More males (63.9%) than females (36.1%) were infected (median ages: 42 (1-68) and 39 years (6-61), respectively). We detected Coxiella burnetii by PCR in faecal, dust and/or aerosol samples taken inside the cave in March 2021, and in dust and aerosol samples collected between March 2021 a...
Source: Euro Surveill - July 13, 2023 Category: Infectious Diseases Authors: Ana Hurtado Ion I Zendoia Eva Alonso Xabier Beraza Joseba Bidaurrazaga Blanca Ocabo I ñaki Arrazola Aitor Cevidanes Jes ús F Barandika Ana L Garc ía-Pérez Source Type: research
B cell-intrinsic TLR7 signaling is required for neutralizing antibody responses to SARS-CoV-2 and pathogen-like COVID-19 vaccines
Eur J Immunol. 2023 Jul 12:e2350437. doi: 10.1002/eji.202350437. Online ahead of print.ABSTRACTToll-like receptor 7 (TLR7) triggers antiviral immune responses through its capacity to recognize single-stranded RNA. TLR7 loss-of-function mutants are associated with life-threatening pneumonia in severe COVID-19 patients. Whereas TLR7-driven innate induction of type I IFN appears central to control SARS-CoV2 virus spreading during the first days of infection, the impact of TLR7-deficiency on adaptive B-cell immunity is less clear. In the present study, we examined the role of TLR7 in the adaptive B cells response to various pa...
Source: European Journal of Immunology - July 13, 2023 Category: Allergy & Immunology Authors: Charles-Henry Miquel Flora Abbas Claire Cenac Charlotte Foret-Lucas Chang Guo Mariette Ducatez Etienne Joly Baidong Hou Jean-Charles Gu éry Source Type: research
A Q fever outbreak among visitors to a natural cave, Bizkaia, Spain, December 2020 to October 2021
We describe a large Q fever outbreak reported in Spain, including 108 cases, 53 with pneumonia and 27 requiring hospitalisations. The first cases were detected in February 2021 among rock climbers visiting a cave in Bizkaia, and the last case was detected in October 2021. Most cases were notified after the Easter holiday (April-May 2021). More males (63.9%) than females (36.1%) were infected (median ages: 42 (1-68) and 39 years (6-61), respectively). We detected Coxiella burnetii by PCR in faecal, dust and/or aerosol samples taken inside the cave in March 2021, and in dust and aerosol samples collected between March 2021 a...
Source: Euro Surveill - July 13, 2023 Category: Infectious Diseases Authors: Ana Hurtado Ion I Zendoia Eva Alonso Xabier Beraza Joseba Bidaurrazaga Blanca Ocabo I ñaki Arrazola Aitor Cevidanes Jes ús F Barandika Ana L Garc ía-Pérez Source Type: research
Position statement on infection screening, prophylaxis, and vaccination in pediatric patients with rheumatic diseases and immunosuppressive therapies, part 2: infection prophylaxis
Conclusion: Based on current evidence and a Delphi process, we provided consensus and updated recommendations on prophylaxis and treatment of infections to guide those caring for pediatric rheumatology patients. What is Known: •Data largely derived from adults find that infectious diseases and related complications are a major cause of morbidity and mortality in patients with immune-mediated rheumatic diseases. •It is crucial to be aware of the preventive measures that should be implemented to prevent these infections in children, although most guidelines are often extrapolated from adult cases. What is New: •In the ...
Source: Herpes - July 13, 2023 Category: Infectious Diseases Authors: Daniel Clemente Garulo Esmeralda N úñez-Cuadros Marisol Camacho Lovillo Joan Calzada-Hern ández Sara Guill én Martín Laura Fern ández Silveira Mar ía José Lirola Cruz Alfredo Tagarro Rosa Mar ía Alcobendas Rueda Agust ín López López Miren Satr Source Type: research
20 ‑Valent Pneumococcal Conjugate Vaccine: Pediatric First Approval
This article summarizes the milestones in the development of PCV20 leading to this first pediatric approval for active immunization for the prevention of IPD and otitis media caused by S. pneumoniae.PMID:37440125 | DOI:10.1007/s40272-023-00584-9
Source: Paediatric Drugs - July 13, 2023 Category: Pediatrics Authors: Matt Shirley Source Type: research
