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Vaccination: Pneomococcal Vaccine

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A Q fever outbreak among visitors to a natural cave, Bizkaia, Spain, December 2020 to October 2021
We describe a large Q fever outbreak reported in Spain, including 108 cases, 53 with pneumonia and 27 requiring hospitalisations. The first cases were detected in February 2021 among rock climbers visiting a cave in Bizkaia, and the last case was detected in October 2021. Most cases were notified after the Easter holiday (April-May 2021). More males (63.9%) than females (36.1%) were infected (median ages: 42 (1-68) and 39 years (6-61), respectively). We detected Coxiella burnetii by PCR in faecal, dust and/or aerosol samples taken inside the cave in March 2021, and in dust and aerosol samples collected between March 2021 a...
Source: Euro Surveill - July 13, 2023 Category: Infectious Diseases Authors: Ana Hurtado Ion I Zendoia Eva Alonso Xabier Beraza Joseba Bidaurrazaga Blanca Ocabo I ñaki Arrazola Aitor Cevidanes Jes ús F Barandika Ana L Garc ía-Pérez Source Type: research

Distinct Features of Vascular Diseases in COVID-19
J Inflamm Res. 2023 Jul 6;16:2783-2800. doi: 10.2147/JIR.S417691. eCollection 2023.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic was declared in early 2020 after several unexplained pneumonia cases were first reported in Wuhan, China, and subsequently in other parts of the world. Commonly, the disease comprises several clinical features, including high temperature, dry cough, shortness of breath, and hypoxia, associated with findings of interstitial pneumonia on chest X-ray and computer tomography. Nevertheless, severe forms of acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) are not limited to the ...
Source: Atherosclerosis - July 12, 2023 Category: Cardiology Authors: Alexandr Ceasovschih Victorita Sorodoc Annabelle Shor Raluca Ecaterina Haliga Lynn Roth Catalina Lionte Viviana Onofrei Aursulesei Oana Sirbu Nicolae Culis Albina Shapieva Mohammed A R Tahir Khokhar Cristian Statescu Radu A Sascau Adorata Elena Coman Alex Source Type: research

Expert Review on Nonsurgical Management of Parapneumonic Effusion: Advances, Controversies, and New Directions
Semin Respir Crit Care Med. 2023 Aug;44(4):468-476. doi: 10.1055/s-0043-1769095. Epub 2023 Jul 10.ABSTRACTParapneumonic effusion and empyema are rising in incidence worldwide, particularly in association with comorbidities in an aging population. Also driving this change is the widespread uptake of pneumococcal vaccines, leading to the emergence of nonvaccine-type pneumococci and other bacteria. Early treatment with systemic antibiotics is essential but should be guided by local microbial guidelines and antimicrobial resistance patterns due to significant geographical variation. Thoracic ultrasound has emerged as a leading...
Source: Respiratory Care - July 10, 2023 Category: Respiratory Medicine Authors: Deirdre B Fitzgerald Eva Polverino Grant W Waterer Source Type: research

Status of New Vaccine Introduction - Worldwide, 2016-2021
This report describes the status of introductions globally for eight World Health Organization (WHO)-recommended new and underutilized vaccines, comprising 10 individual vaccine antigens. By 2021, among 194 countries worldwide, 33 (17%) provided all of these 10 WHO-recommended antigens as part of their routine immunization schedules; only one low-income country had introduced all of these recommended vaccines. Universal hepatitis B birth dose; human papillomavirus vaccine; rotavirus vaccine; and diphtheria, tetanus, and pertussis-containing vaccine first booster dose have been introduced by 57%, 59%, 60%, and 72% of all co...
Source: MMWR Morb Mortal Wkl... - July 6, 2023 Category: Epidemiology Authors: Gurpreet Kaur Rebecca M Casey Jaymin C Patel Paul Bloem Jenny A Walldorf Terri B Hyde Source Type: research

Management and outcome of COVID-19 in CTLA-4 insufficiency
We report the clinical course of 22 patients with CTLA-4 insufficiency and COVID-19 and retrospectively examine autoantibodies to type 1 interferons at baseline. Data was obtained from patient interview and chart review. Screening for anti-IFN autoantibodies was carried out using a multiplex particle-based assay. Student's T-test, Mann Whitney, ANOVA, or chi squared tests were used where appropriate. Twenty-two patients, ages 8 months to 54 years old, with genetically confirmed CLTA-4 insufficiency, developed COVID-19 from 2020-2022. Most common symptoms were fever, cough, and nasal congestion, and median duration of illne...
Source: Adv Data - July 5, 2023 Category: Epidemiology Authors: Sebastian Ochoa Gonzalez Michael S Abers Lindsey Belle Rosen Amy Rump Katherine N Howe Jay A Lieberman Benjamin L Wright Daniel Suez M áté Krausz Bodo Grimbacher Michail S Lionakis Gulbu Uzel Source Type: research

Preventive health care in blood cancer survivors: results from the ABC study
CONCLUSIONS: Utilization of preventive care is high among German blood cancer survivors. To ensure widespread delivery and avoid redundancy, communication between oncologists and preventive care providers is essential.PMID:37395845 | DOI:10.1007/s00432-023-04984-9
Source: Clinical Genitourinary Cancer - July 3, 2023 Category: Cancer & Oncology Authors: Julia Baum Hildegard Lax Nils Lehmann Anja Merkel-Jens Dietrich W Beelen Karl-Heinz J öckel Ulrich D ührsen Source Type: research