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Vaccination: Pneomococcal Vaccine
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Total 3041 results found since Jan 2013.
Adherence to vaccination guidelines of patients with complete splenectomy in Norway, 2008-2020
This study assessed vaccination coverage (VC) among Norwegian patients with surgical asplenia. Using the Nomesco Classification of Surgical Procedures codes, patient information (age, sex, date of initial diagnosis and date of surgery) was acquired from the Norwegian Patient Registry. The National Immunization Register provided information on vaccination status and data of any subsequent invasive bacterial infections were obtained from the Norwegian Surveillance System for Communicable Diseases. From the total population of Norway, 3155 patients who had undergone complete splenectomy were identified. Of these, 914 (29.0%) ...
Source: Vaccine - June 19, 2023 Category: Allergy & Immunology Authors: Saima Orangzeb Sara Viksmoen Watle Dominique A Caugant Source Type: research
Low let-7d microRNA levels in chick embryos enhance innate immunity against Mycoplasma gallisepticum by suppressing the mitogen-activated protein kinase pathway
In conclusion, chick embryos protect themselves against MG infection through the innate immune molecule let-7d, which may result from its function as an inhibitor of the MAPK pathway to effectively mitigate MG adhesion, the inflammatory response and cell apoptosis. This study may provide new insight into the development of vaccines against MG.PMID:37337278 | PMC:PMC10278363 | DOI:10.1186/s13567-023-01178-6
Source: Cell Research - June 19, 2023 Category: Cytology Authors: Yingjie Wang Huanling Sun Wenqing Zhao Tengfei Wang Mengyun Zou Yun Han Yingfei Sun Xiuli Peng Source Type: research
Incidence and clinical outcomes of pneumonia in persons with down syndrome in the United States
CONCLUSIONS: Among persons with DS, incidence of pneumonia and associated hospitalizations were increased; mortality among those with pneumonia was comparable at 30 days, but higher at 1 year. DS should be considered an independent risk condition for pneumonia.PMID:37328350 | DOI:10.1016/j.vaccine.2023.05.063
Source: Vaccine - June 16, 2023 Category: Allergy & Immunology Authors: Edward N Janoff Hung-Fu Tseng Jennifer L Nguyen Tamuno Alfred Jeffrey Vietri Angee McDaniel Erica Chilson Qi Yan Deepa Malhotra Raul E Isturiz Myron J Levin Source Type: research
Impact of aluminum adjuvants on the stability of pneumococcal polysaccharide-protein conjugate vaccines
This study suggests a formulation, which includes AAHS, may negatively impact the stability of a pneumococcal polysaccharide-protein conjugate vaccine that contains phosphodiester groups. This decrease in stability would likely result in a decrease in the "active" concentration of antigen dose, and herein, it is shown that such instability directly compromised vaccine immunogenicity in an animal model. The results presented in this study help to explain critical degradation mechanisms of pneumococcal polysaccharide-protein conjugate vaccines.PMID:37321893 | DOI:10.1016/j.vaccine.2023.05.059
Source: Vaccine - June 15, 2023 Category: Allergy & Immunology Authors: William J Smith Rachel Thompson Patricia M Egan Yuhua Zhang Lani Indrawati Julie M Skinner Jeffrey T Blue Michael A Winters Source Type: research
Cost-effectiveness of an in-development adult-formulated pneumococcal vaccine in older US adults
CONCLUSION: An in-development PCV21 vaccine would likely be economically and clinically favorable compared to currently recommended pneumococcal vaccines in older adults. While PCV21 was more favorable in Black cohort analyses, results for both Black and non-Black populations were economically reasonable, highlighting the potential importance of adult-specific pneumococcal vaccine formulations and, pending further investigation, potentially justifying a future general population recommendation for PCV21 use in older adults.PMID:37316409 | DOI:10.1016/j.vaccine.2023.06.007
Source: Vaccine - June 14, 2023 Category: Allergy & Immunology Authors: Angela R Wateska Mary Patricia Nowalk Chyongchiou J Lin Lee H Harrison William Schaffner Richard K Zimmerman Kenneth J Smith Source Type: research
Predictors of serological non-response to the 13-valent pneumococcal conjugate vaccine followed by the 23-valent polysaccharide vaccine among adults living with HIV
CONCLUSION: Less than half of our study population achieved anti-pneumococcal seroprotective levels following PCV13 and PPV23 immunization. Low pre-vaccination GMC levels were associated with non-response. Further research is required to optimize vaccination strategies that achieve higher seroprotection in this high-risk group.PMID:37316406 | DOI:10.1016/j.vaccine.2023.06.021
Source: Vaccine - June 14, 2023 Category: Allergy & Immunology Authors: Michaela Tinggaard Hans-Christian Slotved Charlotte Sv ærke Jørgensen Gitte Kronborg Thomas Benfield Source Type: research
Cost-effectiveness of an in-development adult-formulated pneumococcal vaccine in older US adults
CONCLUSION: An in-development PCV21 vaccine would likely be economically and clinically favorable compared to currently recommended pneumococcal vaccines in older adults. While PCV21 was more favorable in Black cohort analyses, results for both Black and non-Black populations were economically reasonable, highlighting the potential importance of adult-specific pneumococcal vaccine formulations and, pending further investigation, potentially justifying a future general population recommendation for PCV21 use in older adults.PMID:37316409 | DOI:10.1016/j.vaccine.2023.06.007
Source: Vaccine - June 14, 2023 Category: Allergy & Immunology Authors: Angela R Wateska Mary Patricia Nowalk Chyongchiou J Lin Lee H Harrison William Schaffner Richard K Zimmerman Kenneth J Smith Source Type: research
Predictors of serological non-response to the 13-valent pneumococcal conjugate vaccine followed by the 23-valent polysaccharide vaccine among adults living with HIV
CONCLUSION: Less than half of our study population achieved anti-pneumococcal seroprotective levels following PCV13 and PPV23 immunization. Low pre-vaccination GMC levels were associated with non-response. Further research is required to optimize vaccination strategies that achieve higher seroprotection in this high-risk group.PMID:37316406 | DOI:10.1016/j.vaccine.2023.06.021
Source: Vaccine - June 14, 2023 Category: Allergy & Immunology Authors: Michaela Tinggaard Hans-Christian Slotved Charlotte Sv ærke Jørgensen Gitte Kronborg Thomas Benfield Source Type: research
Study on acute respiratory infection in children aged 1 year to 5 years-A hospital-based cross-sectional study
CONCLUSION: The studies regarding factors influencing ARI are relatively rare in an urban setting, thus this calls for more studies in urban areas. Health education can change the healthcare-seeking behavior and attitude of parents for preventing ARI-related deaths. Family physicians can play a significant role by educating caregivers of children and giving timely services. Promoting and ensuring exclusive breastfeeding practices, timely weaning after 6 months, and avoidance of bottle feeds can dramatically decrease the episodes of ARI.PMID:37312761 | PMC:PMC10259544 | DOI:10.4103/jfmpc.jfmpc_1748_22
Source: Primary Care - June 14, 2023 Category: Primary Care Authors: Anuna Vinod Resmi S Kaimal Source Type: research
COVID-19-induced Esophageal Necrosis Requiring Emergent Total Esophagectomy in a Vaccinated Patient
Am Surg. 2023 Jun 9:31348231183125. doi: 10.1177/00031348231183125. Online ahead of print.ABSTRACTAcute esophageal necrosis may be a potential complication of Coronavirus Disease 2019 (COVID-19). COVID-19 has been associated with a variety of sequelae, including acute respiratory distress syndrome, myocarditis, and thromboembolic events. Here, we present a case of a 43-year-old male who was admitted for acute necrotizing pancreatitis and found to have COVID-19 pneumonia. He subsequently developed acute esophageal necrosis requiring a total esophagectomy. Currently, there are at least five other reported cases of esophageal...
Source: The American Surgeon - June 9, 2023 Category: Surgery Authors: Tanmay Patil Kevin M Dickson Matthew Viera Bryce M Bludevich Ali Akalin Karl Uy Feiran Lou Mark W Maxfield Source Type: research
Serotypes and antimicrobial resistance of < em > Streptococcus pneumoniae < /em > in children under 5 years of age pre- and post-pneumococcal conjugate vaccine introduction in Paraguay
Conclusion. A change in the circulating serotypes and antimicrobial resistance to certain antibiotics was observed. Non-vaccine serotype circulation and multidrug resistance may compromise the success of the conjugate vaccines.PMID:37289483 | DOI:10.1099/jmm.0.001700
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Mar ía Eugenia León Margarita Samudio An íbal Kawabata Minako Nagai Liliana Rojas Noem í Zárate Juan Irala Myrian Leguizam ón Gloria G ómez Juana Ortellado Raquel Blasco Rossana Franco Gustavo Chamorro Source Type: research
