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Vaccination: Pneomococcal Vaccine
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Total 3041 results found since Jan 2013.
Meningitis Risk and Role of Prophylactic Antibiotics in Spontaneous Lateral Skull Base CSF Leaks
CONCLUSIONS: There appears to be a low risk of meningitis among patients with lateral skull base sCSF leaks awaiting surgery for short durations (≤2 months), even in the absence of prophylactic antibiotics. There is a substantial gap in the published literature assessing the risk of meningitis and roles of antibiotics and vaccination in this patient population, indicating the need for large-scale study to conclusively elucidate the nature of this risk.PMID:37246394 | DOI:10.1177/00034894231177756
Source: The Annals of Otology, Rhinology, and Laryngology - May 29, 2023 Category: ENT & OMF Authors: Alexandra E Quimby Emma De Ravin Steven J Eliades Jason A Brant Douglas Bigelow Michael J Ruckenstein Source Type: research
Estimating global changes in routine childhood vaccination coverage during the COVID-19 pandemic, 2020-2021
CONCLUSION: The COVID-19 pandemic exerted larger disruptions to routine vaccination services in 2021 than in 2020. Global efforts will be needed to recoup vaccine coverage losses sustained during the pandemic and broaden vaccine access in areas where coverage was previously inadequate.PMID:37246068 | PMC:PMC10201316 | DOI:10.1016/j.vaccine.2023.05.034
Source: Vaccine - May 28, 2023 Category: Allergy & Immunology Authors: Cyrus Ghaznavi Akifumi Eguchi Kaung Suu Lwin Daisuke Yoneoka Yuta Tanoue Santosh Kumar Rauniyar Sayaka Horiuchi Masahiro Hashizume Shuhei Nomura Source Type: research
Randomized trial to evaluate the safety, tolerability, and immunogenicity of a booster (third dose) of BNT162b2 COVID-19 vaccine coadministered with 20-valent pneumococcal conjugate vaccine in adults ≥65 years old
CONCLUSIONS: Safety and immunogenicity of coadministered PCV20 and BNT162b2 were similar to those of PCV20 or BNT162b2 administered alone, suggesting that the 2 vaccines may be coadministered.TRIAL REGISTRATION: ClinicalTrials.gov, NCT04887948.PMID:37244809 | PMC:PMC10165018 | DOI:10.1016/j.vaccine.2023.05.002
Source: Vaccine - May 27, 2023 Category: Allergy & Immunology Authors: David Fitz-Patrick Mariano Young Kari Yacisin Kathleen McElwee Todd Belanger Kelly Belanger Yahong Peng Dung-Yang Lee William C Gruber Daniel A Scott Wendy Watson Source Type: research
A retrospective cohort study investigating the comparative effectiveness of pneumococcal vaccines against hospitalisation with otitis media and pneumonia in New Zealand
CONCLUSION: These results should offer reassurance about the equivalence of these pneumococcal vaccines against the broader pneumococcal disease outcomes OM and pneumonia.PMID:37244807 | DOI:10.1016/j.vaccine.2023.05.040
Source: Vaccine - May 27, 2023 Category: Allergy & Immunology Authors: Janine Paynter Anna S Howe Emma Best Helen Petousis-Harris Source Type: research
Immune responses and protection against Streptococcus pneumoniae elicited by recombinant Bordetella pertussis adenylate cyclase (CyaA) carrying fragments of pneumococcal surface protein A, PspA
Vaccine. 2023 May 24:S0264-410X(23)00570-4. doi: 10.1016/j.vaccine.2023.05.031. Online ahead of print.ABSTRACTStreptococcus pneumoniae is a common agent of important human diseases such as otitis media, pneumonia, meningitis and sepsis. Current available vaccines that target capsular polysaccharides induce protection against invasive disease and nasopharyngeal colonization in children, yet their efficacy is limited to the serotypes included in the formulations. The virulence factor Pneumococcal Surface Protein A (PspA) interacts with host immune system and helps the bacteria to evade phagocytosis. Due to its essential role...
Source: Vaccine - May 26, 2023 Category: Allergy & Immunology Authors: Giovanna Brito Carneiro Julia Tavares Castro Marilyne Davi Eliane Namie Miyaji Daniel Ladant Maria Leonor Sarno Oliveira Source Type: research
Obesity as an independent risk factor for COVID-19 severity and mortality
CONCLUSIONS: Our findings suggest that obesity is an important independent prognostic factor in the setting of COVID-19. Consideration of obesity may inform the optimal management and allocation of limited resources in the care of COVID-19 patients.PMID:37222292 | PMC:PMC10207996 | DOI:10.1002/14651858.CD015201
Source: Cochrane Database of Systematic Reviews - May 24, 2023 Category: General Medicine Authors: Borna Tadayon Najafabadi Daniel G Rayner Kamyar Shokraee Kamran Shokraie Parsa Panahi Paravaneh Rastgou Farnoosh Seirafianpour Feryal Momeni Landi Pariya Alinia Neda Parnianfard Nima Hemmati Behrooz Banivaheb Ramin Radmanesh Saba Alvand Parmida Shahbazi H Source Type: research
Challenges in the Vaccination of the Elderly and Strategies for Improvement
This article reviews published papers on several vaccination strategies that were developed for the elderly to solve these problems: more immunogenic vaccine formulations using larger doses of antigen, stronger vaccine adjuvants, recombinant subunit or protein conjugated vaccines, newly developed mRNA vaccines, giving booster shots, and exploring alternative routes of administration. Included also are several publications on senolytic medications under investigation to boost the immune system and vaccine response in the elderly. With all those in regard, the currently recommended vaccines for the elderly are presented.PMID...
Source: Herpes - May 23, 2023 Category: Infectious Diseases Authors: Gatot Soegiarto Dewajani Purnomosari Source Type: research
Cardiorespiratory Adverse Events after First Vaccination in Preterm Neonates With Gestational Age & lt;30 Weeks
CONCLUSION: Adverse cardiorespiratory events were uncommon after first vaccinations in very preterm neonates. Administering vaccines to these before discharge would allow monitoring for these events, especially for those who require long-term respiratory support.PMID:37211893
Source: Indian Pediatrics - May 22, 2023 Category: Pediatrics Authors: Hima Surendran Femitha Pournami Anila V Panackal Ajai Kumar Prithvi Jyothi Prabhakar Naveen Jain Source Type: research
