Hippocratic AI Raises $53 Million Series A at a $500 Million Valuation
Company Releases First Product: Generative AI-Powered Staffing Marketplace for Healthcare and will use Funds to Accelerate Further Product Development and Conduct Phase Three Safety Testing for its LLM Hippocratic AI, the company building the first safety-focused Large Language Model (LLM) for healthcare, today announced the close of a $53 million Series A funding round at a $500 million valuation, bringing total funding to $120 million. Today, the company also released its first product for phase three safety testing: a staffing marketplace for healthcare where health systems, payors, and others can “hire” generative ...
Source: EMR and HIPAA - April 22, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT a16z Andreessen Horowitz Bio Health Capsule Cincinnati Children’s ELNA Evernow Fraser Health General Catalyst Guidehealth HarmonyCares Health IT Funding Health IT Fundings Health IT Investmen Source Type: blogs

What is the link between thyroid and heart disease?
Heart disease can occur with both increased function of the thyroid gland and decreased function of the thyroid gland. When thyroid function is increased, heart rate increases and the work load of the heart increases. In severe cases heart failure may occur. A peculiarity of heart failure associated with increased thyroid function is that it is a high output failure unlike the usual heart failure in which the pumping function of the heart is reduced, and low output failure occurs. While in low output heart failure the extremities are cold, in high output failure due to increased thyroid function, the extremities of the lim...
Source: Cardiophile MD - April 22, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Corvia atrial shunt system: Mean LA pressure reduction device in HFpEF
Lowering the raised LA mean pressure is a major therapeutic goal in any severely symptomatic left heart disease, whether it is valvular or myocardial disease. It is prudent to understand, that even in systolic LV failure; it is the raised LVEDP that causes the symptoms and marks the limits of exercise capacity. Drugs like inotropes, pre-load , afterload modulators like diuretics and vasodilators can take care to a certain extent. When symptoms are refractory and the underlying condition has no primary correction , we need to intervene with some extreme procedures. We know a small ASD decompresses mitral stenosis, and th...
Source: Dr.S.Venkatesan MD - April 18, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized acquired asd in hfpef atrial flow regulator corvia atrial shunt system decompression of left atrium hhpef lutembacher syndrome Source Type: blogs

The current STEMI paradigm: Because STEMI criteria are not met, let's wait until the myocardium is dead!!
This was sent to me by an inpatient nurse who reads this blog but wants to remain anonymous.An inpatient rapid response was called for a patient with hypotension.  The patient was originally admitted for pneumonia and had been transferred out of the ICU a day prior. He had a history of HFrEF, HTN, and AML. " When I arrived his blood pressure was 70s/40s and he was pale and profusely diaphoretic. " " He spoke Spanish but we did deduce that he had 7/10 chest pain radiating to the back. " " We couldn ’t initially get a hold of the primary physician but our hospital allows the rapid response nur...
Source: Dr. Smith's ECG Blog - April 16, 2024 Category: Cardiology Authors: Steve Smith Source Type: blogs

Assessment of LV Diastolic Function by Echo in SR and AF
Echocardiographic assessment of left ventricular diastolic function with special reference on diastolic function assessment in atrial fibrillation. Though there are several parameters for evaluation of left ventricular diastolic function by echocardiography, the most commonly used are the pulsed Doppler mitral E/A ratio and tissue Doppler mitral E/e’ ratio. Some of the other useful parameters are mitral E velocity deceleration time, changes in mitral inflow with Valsalva maneuver, mitral L velocity, isovolumic relaxation time, left atrial maximum volume index, pulmonary vein systolic/diastolic velocity ratio, color M-mod...
Source: Cardiophile MD - April 15, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Fight Aging! Newsletter, April 15th 2024
In conclusion, although several clinical trials targeting SnCs are ongoing, various questions about the biology of SnCs remain open, resulting in a gap between molecular and cellular data. Concerning the need, initiatives such as SenNet aiming to create openly accessible atlases of SnCs should contribute enormously to the area. Advances in understanding the subcellular structure, the heterogeneity, and the dynamics of SnCs require the integration of molecular and cellular techniques with data analysis packages to evaluate high throughput evidence from microscopy and flow cytometry. It is also necessary to develop new equip...
Source: Fight Aging! - April 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Delivery of TGF- β1 Following Heart Attack Reduces Reperfusion Injury
A heart attack is triggered by rupture of an atherosclerotic plaque and downstream blockage of an important vessel feeding oxygenated blood to heart tissue. Much of the permanent harm resulting from a heart attack occurs when blood flow is restored to ischemic tissue, however. A cascade of maladaptive reactions, inflammation, and cell death occurs, leading to scarring and loss of function in the heart muscle. This damage to the heart can be reduced to some degree by anti-inflammatory signaling applied soon after the heart attack takes place, as researchers here demonstrate. Despite major improvements using primary...
Source: Fight Aging! - April 12, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

8 Mindblowing Examples Of Technology Innovation In Healthcare
Medical innovations often conjure images of sterile labs, high-tech equipment, and complex procedures. But every now and then, remarkable breakthroughs come with a dash of ‘why didn’t I think of that?’ ingenuity. From reimagined everyday objects to solutions inspired by the natural world, these innovations prove that effective healthcare doesn’t always need to be complicated. Let’s see some medical innovations that are as surprising as they are effective. We collected eight of our favorites that show how a little out-of-the-box thinking is leading to big changes in healthcare. 1. Zip-up ...
Source: The Medical Futurist - April 9, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF creative healthcare healthcare innovation Source Type: blogs

What is the reason for sudden breathlessness at night in those with heart disease?
Sudden breathlessness at night in those with known heart disease is usually due to collection of fluid in the lungs (pulmonary edema). During day time, when one is walking about, any extra fluid in the body tends to collect in the legs, due to the effect of gravity. Extra fluid in the body can occur due to failure of heart, kidneys, liver and rarely due to other causes. In heart failure, the extra fluid is due to inability of the heart to pump out blood well. This can occur if the heart muscle is weak or there is obstruction to a valve regulating the flow of blood inside the heart. At night, when one is lying down, extra f...
Source: Cardiophile MD - April 8, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Bonus Features – April 7, 2024 – 86% of health systems had at least 10% of nurses quit in 2023, 25% of providers intend to deploy generative AI for patient engagement, plus 21 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. Studies A report from HFS Research and Cognizant found 25% of providers intend to deploy generative AI to enhance patient engagement. A Nursa survey found 86% of health systems had 10% or more of their nursing staff quit in 202...
Source: EMR and HIPAA - April 7, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Adherium Alan Tam Andrew Lundquist Availity Axuall Care Directions Carium Cognizant eClinicalWorks Eko G2 Google Cloud Greg Hajcak H1 Hartford HealthCare Healow Healthcare IT Today Bonus Features HFS Resea Source Type: blogs

Fight Aging! Newsletter, April 1st 2024
This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression can promote increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes. « Back to Top A Skeptical View of the Role of Nuclear DNA Damage in Aging https://www.fightaging.org/archives/2024/03/a-skeptical-view-of-the-role-of-nuclear-dna-damage-in-aging/ It is evident and settled that stochastic nuclear DNA damag...
Source: Fight Aging! - March 31, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Ebstein ’ s Anomaly of Tricuspid Valve
Transcript of the video: Ebstein’s Anomaly is one of the cyanotic congenital heart disease in which survival to adult life is common. In Ebstein’s anomaly, there is downward or apical displacement of posterior and septal tricuspid leaflets. The anterior leaflet is not displaced, but is elongated to meet the other leaflets, so that when it closes, a loud sound, tricuspid sound, is produced, which is called as the sail sound. Ebstein’s anomaly may be associated with atrial septal defect or a patent foramen ovale, in about 50% of cases. The cyanosis in Ebstein’s anomaly, is usually not due to pulmonary...
Source: Cardiophile MD - March 30, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

The Advantages, Challenges, and Costs of Healthcare at Home Services
Switching to fully remote operations during the pandemic was a rushed adventure into what was mostly uncharted territory. There were a lot of challenges and bugs to work out, but there were also plenty of advantages and unforeseen benefits. And it is thanks to those advantages and benefits that healthcare at home is continuing, even as there are still challenges to work on and in-person operations return. While our first big push into remote care was a leap into the unknown, this time we want to make sure that we are surveying the landscape to make this a safe, smart, and financially responsible decision. So let’s ta...
Source: EMR and HIPAA - March 28, 2024 Category: Information Technology Authors: Grayson Miller Tags: Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC Revenue Cycle Management Telemedicine and Remote Monitoring Alaina Victoria Ash Wellness Brenden Hayden Carenet Health Carium Chris Darland David McCormick Source Type: blogs

Important Complications of Eisenmenger Syndrome
Transcript of the video: Eisenmenger syndrome is an important complication of large left to right shunts which develop later due to development of pulmonary vascular obstructive disease and severe pulmonary hypertension. The first report of Eisenmenger was by Victor Eisenmenger in 1897 and that was in a thirty year old person who later succumbed to massive hemoptysis. This highlights one of the most important complications of Eisenmenger syndrome, that is airway hemorrhage. Airway hemorrhage can occur in those who ascend to high altitude and during air travel. But it commonly occurs at low level itself. It is one of the mo...
Source: Cardiophile MD - March 26, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Estrogen-Related Receptor Agonists as Exercise Mimetic Drugs
Just as the research community is interested in finding pharmaceutical ways to provoke some the beneficial reactions to calorie restriction, there is also considerable effort devoted to the search for drug candidates that can mimic some of the benefits of exercise. If the history of calorie restriction mimetic drug development is any guide, this will be a slow process, and the resulting compounds will produce lesser benefits than actual exercise, as they will only touch on a small subset of the processes involved. Still, there is no shortage of programs in this space, and here is one example. Exercise benefits bot...
Source: Fight Aging! - March 25, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs