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Vaccination: Meningitis Vaccine

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Total 2891 results found since Jan 2013.

Pneumococcal vaccines for cystic fibrosis.
CONCLUSIONS: As no trials were identified we cannot draw conclusions on the efficacy of routine pneumococcal immunisation in people with cystic fibrosis in reducing their morbidity or mortality. As many countries now include pneumococcal immunisation in their routine childhood vaccination schedule it is unlikely that future randomised controlled trials will be initiated. Rigorously conducted epidemiological studies may offer the opportunity to evaluate the efficacy of pneumococcal vaccination in reducing morbidity and mortality in people with cystic fibrosis. PMID: 27654832 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - September 21, 2016 Category: Journals (General) Authors: Burgess L, Southern KW Tags: Cochrane Database Syst Rev Source Type: research

Burden of Culture-Confirmed Pediatric Pneumococcal Pneumonia in Latin America and the Caribbean: A Systematic Review and Meta-Analysis
Conclusions Studies on confirmed pediatric PP were scarce in LAC in 2000 to 2016. Epidemiology indicators and health resource use are still poorly defined.
Source: Value in Health Regional Issues - June 10, 2017 Category: International Medicine & Public Health Source Type: research

Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease.
CONCLUSIONS: The evidence examined suggests that prophylactic penicillin significantly reduces risk of pneumococcal infection in children with homozygous SCD, and is associated with minimal adverse reactions. Further research may help to determine the ideal age to safely withdraw penicillin. PMID: 28994899 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - October 10, 2017 Category: General Medicine Authors: Rankine-Mullings AE, Owusu-Ofori S Tags: Cochrane Database Syst Rev Source Type: research

Vaccinations in immunosuppressive-dependent pediatric inflammatory bowel disease.
CONCLUSION: Immunizations have been shown to be well-tolerated and protective immunity can be achieved in patients with IBD requiring immunosuppressive therapy. PMID: 29204064 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - November 14, 2017 Category: Gastroenterology Authors: Nguyen HT, Minar P, Jackson K, Fulkerson PC Tags: World J Gastroenterol Source Type: research

Grommets (ventilation tubes) for recurrent acute otitis media in children.
CONCLUSIONS: Current evidence on the effectiveness of grommets in children with rAOM is limited to five RCTs with unclear or high risk of bias, which were conducted prior to the introduction of pneumococcal vaccination. Low to very low-quality evidence suggests that children receiving grommets are less likely to have AOM recurrences compared to those managed by active monitoring and placebo medication, but the magnitude of the effect is modest with around one fewer episode at six months and a less noticeable effect by 12 months. The low to very low quality of the evidence means that these numbers need to be interpreted wit...
Source: Cochrane Database of Systematic Reviews - May 9, 2018 Category: General Medicine Authors: Venekamp RP, Mick P, Schilder AG, Nunez DA Tags: Cochrane Database Syst Rev Source Type: research

Narrative review of methods and findings of recent studies on the carriage of meningococci and other Neisseria species in the African Meningitis Belt
ConclusionsRecent studies employing standardised methods confirm the findings of older studies that carriage ofN. meningitidis in the African meningitis belt is highly variable over time and place, but generally occurs with a lower prevalence and shorter duration than reported from industrialised countries.This article is protected by copyright. All rights reserved.
Source: Tropical Medicine and International Health - November 21, 2018 Category: Tropical Medicine Authors: Brian M. Greenwood, Abraham Aseffa, Dominique A. Caugant, Kanny Diallo, Paul A. Kristiansen, Martin C.J. Maiden, James M. Stuart, Caroline L. Trotter Tags: Review Article Source Type: research

Exploring the Potential Role of Moonlighting Function of the Surface-Associated Proteins From Mycobacterium bovis BCG Moreau and Pasteur by Comparative Proteomic
In this study, the proteomic profile of the surface-associated proteins from M. bovis BCG Moreau was compared to the BCG Pasteur reference strain. The methodology used was 2DE gel electrophoresis combined with mass spectrometry techniques (MALDI-TOF/TOF), leading to the identification of 115 proteins. Of these, 24 proteins showed differential expression between the two BCG strains. Furthermore, 27 proteins previously described as displaying moonlighting function were identified, 8 of these proteins showed variation in abundance comparing BCG Moreau to Pasteur and 2 of them presented two different domain hits. Moonlighting ...
Source: Frontiers in Immunology - April 25, 2019 Category: Allergy & Immunology Source Type: research

Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondri...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Comprehensive Review of Meningococcal Disease Burden in India
ConclusionMeningococcal disease is prevalent in India but remains grossly underestimated and under-reported. Available literature largely presents outbreak data related to serogroup A disease; however, non-A serogroup disease cases have been reported. Reliable epidemiologic data are urgently needed to inform the true burden of endemic disease. Further research into the significance of meningococcal disease burden can be used to improve public health policy in India.Fig.  1Plain language summary
Source: Infectious Diseases and Therapy - July 22, 2020 Category: Infectious Diseases Source Type: research

IJERPH, Vol. 17, Pages 7589: Vaccination Coverage among Prisoners: A Systematic Review
Tuells Prison inmates are highly susceptible for several infectious diseases, including vaccine-preventable diseases. We conducted a systematic international literature review on vaccination coverage against hepatitis B virus (HBV), hepatitis A virus (HAV), combined HAV/HBV, tetanus-diphtheria, influenza, pneumococcal, and combined measles, mumps, and rubella (MMR) in prison inmates, according to the PRISMA guidelines. The electronic databases were used Web of Science, MEDLINE, Scopus, and Cinhal. No language or time limit were applied to the search. We defined vaccination coverage as the proportion of vaccinated priso...
Source: International Journal of Environmental Research and Public Health - October 19, 2020 Category: Environmental Health Authors: Nancy Vicente-Alcalde Esther Ruescas-Escolano Zitta Barrella Harboe Jos é Tuells Tags: Review Source Type: research

What It Really Feels Like to Have Monkeypox
Since the global monkeypox outbreak began in May 2022, more than 22,000 cases have been confirmed in countries around the world. More than 5,000 of those cases have been recorded in the U.S., with many clustered in hotspots including New York and California. The virus, which often results in a blister-like rash and spreads through close contact, has so far predominantly affected men who have sex with men. Even as cases tick up and monkeypox gains public attention, however, it can still be difficult to find information about testing, treatment, and vaccines. Many people who fear they are at risk or infected are left to seek...
Source: TIME: Health - August 1, 2022 Category: Consumer Health News Authors: Jamie Ducharme, Angela Haupt and Jeffrey Kluger Tags: Uncategorized healthscienceclimate monkeypox Source Type: news

The status of Streptococcus pneumoniae in Iran compared to the world: a systematic review
Conclusion: Since pneumococcal serotypes differ in invasiveness, virulence, and antibiotic resistance it is important to closely monitor the changes on evolving serotypes, antibiotic resistance and virulence factors of this pathogen to be able to implement suitable prevention and therapeutic strategies.
Source: Reviews in Medical Microbiology - October 1, 2022 Category: Microbiology Tags: BACTERIOLOGY Source Type: research

Accounting for Adverse Events Following Immunization in Economic Evaluation: Systematic Review of Economic Evaluations of Pediatric Vaccines Against Pneumococcus, Rotavirus, Human Papillomavirus, Meningococcus and Measles-Mumps-Rubella-Varicella
DiscussionAlthough (mild) AEFI were demonstrated for all five studied vaccines, only a quarter of reviewed studies accounted for these, mostly in an incomplete and inaccurate manner. We provide guidance on which methods to use to better quantify the impact of AEFI on both costs and health outcomes. Policymakers should be aware that the impact of AEFI on cost-effectiveness is likely to be underestimated in the majority of economic evaluations.
Source: PharmacoEconomics - February 21, 2023 Category: Health Management Source Type: research

Healthcare workers' perceptions and experiences of communicating with people over 50 years of age about vaccination: a qualitative evidence synthesis
CONCLUSIONS: There is little research focusing specifically on healthcare workers' perceptions and experiences of communication with older adults about vaccination. The studies we identified suggest that healthcare workers differed among themselves in their perceptions about the aim of this communication and about the role of older adults in vaccine decisions. Based on these findings and the other findings in our review, we have developed a set of questions or prompts that may help health system planners or programme managers when planning or implementing strategies for vaccination communication between healthcare workers ...
Source: Cochrane Database of Systematic Reviews - July 20, 2021 Category: General Medicine Authors: Claire Glenton Benedicte Carlsen Simon Lewin Manuela Dominique Wennekes Brita Askeland Winje Renske Eilers VITAL consortium Source Type: research