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Male kidney-specific BMAL1 knockout mice are protected from Potassium-deficient, high salt diet-induced blood pressure increases
Am J Physiol Renal Physiol. 2023 Sep 14. doi: 10.1152/ajprenal.00126.2023. Online ahead of print.ABSTRACTThe circadian clock protein BMAL1 is a transcription factor that impacts kidney function, including blood pressure (BP) control. Previously, we showed that male, but not female, kidney-specific cadherin Cre positive BMAL1 knockout mice (KS-BMAL1 KO) exhibit lower BP compared to littermate controls. The goal of this study was to determine the BP phenotype and immune response in male KS-BMAL1 KO in response to a low potassium, high salt diet (LKHS). BP, renal inflammatory markers and immune cells were measured in male mic...
Source: Am J Physiol Renal P... - September 14, 2023 Category: Urology & Nephrology Authors: G Ryan Crislip Hannah M Costello Alexandria Juffre Kit-Yan Cheng I Jeanette Lynch Jermaine G Johnston Charles B Drucker Phillip Bratanatawira Annanya Agarwal Victor M Mendez Ryanne S Thelwell Lauren G Douma Charles S Wingo Abdel A Alli Yogesh M Scindia Mi Source Type: research
Exploring diet-induced promoter hypomethylation and PDK4 overexpression: implications for type 2 diabetes mellitus
CONCLUSIONS: These findings suggest that T2DM can be induced by high-carbohydrate and high-MSG diets. However, the sole consumption of high MSG did not lead to the development of T2DM. Further research should focus on conducting long-term studies to fully comprehend the impact of a high MSG diet on individuals with pre-existing T2DM.PMID:37707772 | DOI:10.1007/s11033-023-08794-7
Source: Molecular Biology Reports - September 14, 2023 Category: Molecular Biology Authors: Sulistyo Emantoko Dwi Putra Farizky Martriano Humardani Lisa Thalia Mulyanata Lady Theresa Adeodata Tanaya Heru Wijono Hikmawan Wahyu Sulistomo Dini Kesuma Risma Ikawaty Source Type: research
Male kidney-specific BMAL1 knockout mice are protected from Potassium-deficient, high salt diet-induced blood pressure increases
Am J Physiol Renal Physiol. 2023 Sep 14. doi: 10.1152/ajprenal.00126.2023. Online ahead of print.ABSTRACTThe circadian clock protein BMAL1 is a transcription factor that impacts kidney function, including blood pressure (BP) control. Previously, we showed that male, but not female, kidney-specific cadherin Cre positive BMAL1 knockout mice (KS-BMAL1 KO) exhibit lower BP compared to littermate controls. The goal of this study was to determine the BP phenotype and immune response in male KS-BMAL1 KO in response to a low potassium, high salt diet (LKHS). BP, renal inflammatory markers and immune cells were measured in male mic...
Source: American Journal of Physiology. Renal Physiology - September 14, 2023 Category: Physiology Authors: G Ryan Crislip Hannah M Costello Alexandria Juffre Kit-Yan Cheng I Jeanette Lynch Jermaine G Johnston Charles B Drucker Phillip Bratanatawira Annanya Agarwal Victor M Mendez Ryanne S Thelwell Lauren G Douma Charles S Wingo Abdel A Alli Yogesh M Scindia Mi Source Type: research
Idiopathic pulmonary fibrosis (IPF): disease pathophysiology, targets, and potential therapeutic interventions
In this study, we focus on the IPF and COVID-19 pathogenesis and the potential role of Apigenin in addressing disease progression.PMID:37707699 | DOI:10.1007/s11010-023-04845-6
Source: Molecular and Cellular Biochemistry - September 14, 2023 Category: Biochemistry Authors: Pritha Saha Priti Talwar Source Type: research
Low concentrations of perfluoroalkyl acids (PFAAs) in municipal drinking water associated with serum PFAA concentrations in Swedish adolescents
In conclusion, PFAA exposure from low-level contaminated DW must be considered in risk assessment for adolescents.PMID:37708812 | DOI:10.1016/j.envint.2023.108166
Source: Environment International - September 14, 2023 Category: Environmental Health Authors: Jennifer Nystr öm-Kandola Lutz Ahrens Anders Glynn Gunnar Johanson Jonathan P Benskin Irina Gyllenhammar Sanna Lignell Carolina Vogs Source Type: research
Total Energy Expenditure and Nutritional Intake in Continuous Multiday Ultramarathon Events
Int J Sport Nutr Exerc Metab. 2023 Sep 14:1-7. doi: 10.1123/ijsnem.2023-0063. Online ahead of print.ABSTRACTContinuous multiday ultramarathon competitions are increasingly popular and impose extreme energetic and nutritional demands on competitors. However, few data have been published on energy expenditure during these events. Here, we report doubly labeled water-derived measures of total energy expenditure (in kilocalories per day) and estimated physical activity level (PAL: total energy expenditure/basal metabolic rate) collected from five elite and subelite finishers (four males and one female, age 34.6 ± 4.9 years)-a...
Source: International Journal of Sport Nutrition and Exercise Metabolism - September 14, 2023 Category: Sports Medicine Authors: Andrew W Best Amanda McGrosky Zane Swanson Rebecca Rimbach Katie McConaughy Joe McConaughy Cara Ocobock Herman Pontzer Source Type: research
Appearance comparison on Instagram: The impact of fitspiration and transformation imagery on young women's body satisfaction
Eat Behav. 2023 Sep 12;51:101812. doi: 10.1016/j.eatbeh.2023.101812. Online ahead of print.ABSTRACTFitspiration, or imagery of thin muscular individuals that displays their physiques while posing or exercising, is a popular type of content on Instagram which ostensibly exists to encourage individuals to engage in a healthy lifestyle. A subtype of fitspiration imagery, "transformation" imagery, depicts physical changes following a "lifestyle change" involving diet and exercise. Despite its intentions, fitspiration imagery largely promotes one idealized body type (the fit ideal) and can be accompanied by messages encouraging...
Source: Eating Behaviors - September 14, 2023 Category: Eating Disorders & Weight Management Authors: Lindsay Samson Shannon L Zaitsoff Source Type: research
The effects of brief diet and anti-diet social media videos on body image and eating concerns among young women
Eat Behav. 2023 Sep 12;51:101811. doi: 10.1016/j.eatbeh.2023.101811. Online ahead of print.ABSTRACTThe effects of photo-based platforms on body image concerns are well documented, yet it is unknown whether these effects replicate across video-based platforms such as TikTok. Thus, this experimental study aimed to examine the relationship between video-based platform use and body image. Women aged 18 to 21 (n = 421) were randomly assigned to watch two brief, consecutive TikTok videos in one of three conditions: (1) diet culture, (2) anti-diet, (3) neutral. Participants allocated to the anti-diet condition reported greater in...
Source: Eating Behaviors - September 14, 2023 Category: Eating Disorders & Weight Management Authors: Angelica Fiuza Rachel F Rodgers Source Type: research
Enrichment of sialic acid-containing casein glycomacropeptide in protein hydrolysates using phenylboronic acid-functionalized mesoporous silica nanoparticles
Talanta. 2023 Sep 9;267:125174. doi: 10.1016/j.talanta.2023.125174. Online ahead of print.ABSTRACTGlycomacropeptide (GMP) is a bioactive peptide of high value, rich in glycosylation sites and with physiological and dietary therapeutic value. The enrichment and detection of GMP facilitates the accurate quantification and the identification of adulteration of GMP in food products. In GMP, sialic acid is an abundant glycosyl group and is mainly located at the end of the sugar chain. Here, we propose a novel GMP enrichment strategy based on the affinity of sialic acid for phenylboronic acid groups that shift with environmental...
Source: Talanta - September 14, 2023 Category: Chemistry Authors: Chenhui Lu Haodong Wei Lizhi Xu Wen-Long Wang Cheng Yang Xueli Shi Hui Gao Yong-Wei Feng Jianzhong Zhou Yi Zhang Source Type: research
High Maternal Adiposity During Pregnancy Programs an Imbalance in the Lipidome and Predisposes to Diet-induced Hepatosteatosis in the Offspring
CONCLUSION: High maternal adiposity during pregnancy programs a susceptibility to diet-induced hepatosteatosis.PMID:37706282 | DOI:10.1042/BSR20231060
Source: Bioscience Reports - September 14, 2023 Category: Biomedical Science Authors: Taylor B Scheidl Jessica L Wager Larissa G Baker Amy L Brightwell Katrina M Melan Sebastian Larion Ousseynou Sarr T R Regnault Stefan J Urbanski Jennifer Thompson Source Type: research
Relative impacts of a virtual cooking and nutrition program for children and families
Appetite. 2023 Sep 12:107041. doi: 10.1016/j.appet.2023.107041. Online ahead of print.ABSTRACTAmong the many factors contributing to increased consumption of ultraprocessed foods, a societal decline in cooking skills is a barrier to achieving healthy dietary patterns among children and adolescents. The current study assessed the effectiveness of a healthy cooking program, its geographic reach, and whether program format (child only, in-person format vs. family-based, virtual format) influenced outcomes. This was a quasi-experimental comparison study using youths' (8-18 years old) pre-post surveys, paired t-tests, propensit...
Source: Appetite - September 14, 2023 Category: Nutrition Authors: Amy Saxe-Custack Sarah Egan Richard Sadler Thomas Wojciechowski Source Type: research
Dietary Effects of Selenium Nanoparticles on Growth Performance, Survival Rate, Chemical Composition, and Muscle Bioaccumulation of Nile Tilapia (Oreochromis niloticus)
This study evaluated the effect of selenium nanoparticles on growth performance, survival rate, chemical composition, and bioaccumulation of selenium in the muscle of Nile tilapia (Oreochromis niloticus). Fish with an average weight of 33.1 ± 1.0 g were distributed in 12 fiberglass tanks and fed for 56 days with different levels of selenium nanoparticles, 0, 0.5, 1, and 2 mg/kg of diet, considered as control, T1, T2, and T3, respectively. Body weight increase (BWI), specific growth rate (SGR), and food conversion ratio (FCR) were significantly influenced by 2 mg/kg of selenium nanoparticles compared to the other treatment...
Source: Biological Trace Element Research - September 14, 2023 Category: Biology Authors: Shervin Sheikh Fariborz Ghojaghi Afshin Ghelichi Sarah Jorjani Source Type: research
Estimating the Jordanian population dietary exposure to pesticides residues: An exploratory deterministic approach
This study uses a deterministic approach as a screening method to determine the population's likelihood of daily dietary exposure to pesticide residues and identify pesticides that require further investigation. We investigated the data from surveillance programs to assess pesticide contamination in food. We also obtained data about the population's estimated consumption of different food items. The daily exposure to pesticide residues through food was estimated with two scenarios (Lu et al., 2006): the lower bound (LB) scenario and (Luo and Zhang, 2009) the upper bound (UB) scenario. The data provided the concentration of...
Source: Food and Chemical Toxicology - September 14, 2023 Category: Food Science Authors: Nour Abdo Muath Y Muheisen Source Type: research
A 90-day feeding study of genetically modi fied maize LP007-1 in wistar han RCC rats
Food Chem Toxicol. 2023 Sep 12:114026. doi: 10.1016/j.fct.2023.114026. Online ahead of print.ABSTRACTLP007-1 is a variety of insect-resistant and herbicide-tolerant maize containing the modified cry1Ab, cry2Ab, vip3Aa and cp4-epsps genes. The food safety assessment of the maize LP007-1 was conducted in Wistar Han RCC rats by a 90-days feeding study. Maize grains from both LP007-1 or its corresponding non-genetically modified control maize AX808 were incorporated into rodent diets at 25% and 50% concentrations by mass and administered to rats (n = 10/sex/group) for 90 days. A commercialized rodent diet was fed to an additi...
Source: Food and Chemical Toxicology - September 14, 2023 Category: Food Science Authors: Qinghong Zhou Shufei Li Miao Zhao Yinghua Liu Ning He Xiaoli Zhou Dianming Zhou Zhiyong Qian Source Type: research
Genetic variants in CD36: emerging role in oral fat perception and food preferences
Nutr Hosp. 2023 Sep 1. doi: 10.20960/nh.04711. Online ahead of print.ABSTRACTCD36 is a receptor involved in physiologic, metabolic and pathologic processes. Due to its affinity for long-chain fatty acids, it has been postulated as a taste receptor of fatty taste. In this review, the emerging genetic evidence linking CD36 to oral fat perception is analyzed. A systematic literature search was conducted in PubMed, published articles from 2000 to 2022 were considered. Multiple studies have shown an association of some genetic variants in CD36 with fat foods preferences and it has been suggested that these variants can modify o...
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Mayra Alejandra Enciso Ram írez Zyanya Reyes Castillo Elia Herminia Vald és Miramontes Source Type: research
