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Therapy: Hyperbaric Oxygen Therapy

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Total 200 results found since Jan 2013.

Cystatin C Is a Crucial Endogenous Protective Determinant Against Stroke Basic Sciences
Conclusions—CysC is a crucial determinant contributing to endogenous neuroprotection. It is also a novel candidate for stroke treatment through maintaining lysosomal membrane integrity.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Zongping Fang, Jiao Deng, Zhixin Wu, Beibei Dong, Shiquan Wang, Xiaodan Chen, Huang Nie, Hailong Dong, Lize Xiong Tags: Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

Delayed Hyperbaric Oxygen Therapy Promotes Neurogenesis Through Reactive Oxygen Species/Hypoxia-Inducible Factor-1{alpha}/{beta}-Catenin Pathway in Middle Cerebral Artery Occlusion Rats Basic Sciences
Conclusions— Delayed HBO enhanced endogenous neurogenesis and improved neurofunctional recovery in the late-chronic phase of stroke possibly mediated by ROS/HIF-1α/β-catenin pathway. Delayed HBO may serve as an alternative treatment to improve long-term recovery of stroke survivors.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Hu, Q., Liang, X., Chen, D., Chen, Y., Doycheva, D., Tang, J., Tang, J., Zhang, J. H. Tags: Animal models of human disease, Other Stroke Treatment - Medical Basic Sciences Source Type: research

Hyperbaric oxygen treatment new player in stroke rehabilitation
Treatment with hyperbaric oxygen therapy can lead to significant neurologic improvements for stroke patients, show study results.
Source: MedWire News - Stroke - January 30, 2013 Category: Neurology Source Type: news

Stroke Incidence in Survivors of Carbon Monoxide Poisoning in South Korea: A Population-Based Longitudinal Study.
CONCLUSIONS CO poisoning is a high-risk factor for the development of stroke, evidenced by high incidences of stroke after CO poisoning. Practical strategies for preventing stroke after CO poisoning are needed, because stroke after CO poisoning affects adults of almost all ages, significantly increasing their socioeconomic burden. PMID: 33106468 [PubMed - in process]
Source: Medical Science Monitor - October 28, 2020 Category: Research Tags: Med Sci Monit Source Type: research

Hyperbaric oxygen therapy improves neurocognitive functions of post-stroke patients - a retrospective analysis.
CONCLUSIONS: HBOT induces significant improvements in all cognitive domains even in the late chronic stage. The selection of post-stroke patients for HBOT should be based on functional analysis and baseline cognitive scores rather than the stroke type, location or side of lesion. PMID: 31985478 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - January 29, 2020 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Hyperbaric oxygen therapy in acute stroke: is it time for Justitia to open her eyes?
AbstractHypoxia is a critical component of neuronal death in patients with stroke. Therefore increasing oxygenation of brain tissue seems to be a logical therapy against cerebral ischemia. Oxygen therapy exists in two modalities: normobaric hyperoxia therapy and hyperbaric oxygen therapy (HBO). HBO is a therapeutic procedure in which pure (100%) oxygen is administered at greater than atmospheric pressure in HBO therapy chambers. In this review article, we aimed to summarize the current knowledge regarding the therapeutic use of HBO in acute stroke patients. Literature review and electronic search were performed using PubMe...
Source: Neurological Sciences - January 10, 2020 Category: Neurology Source Type: research

Hyperbaric oxygen therapy for acute ischaemic stroke.
CONCLUSIONS: We found no good evidence to show that HBOT improves clinical outcomes when applied during acute presentation of ischaemic stroke. Although evidence from the 11 RCTs is insufficient to provide clear guidelines for practice, the possibility of clinical benefit has not been excluded. Further research is required to better define the role of HBOT in this condition. PMID: 25387992 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - November 12, 2014 Category: Journals (General) Authors: Bennett MH, Weibel S, Wasiak J, Schnabel A, French C, Kranke P Tags: Cochrane Database Syst Rev Source Type: research

Osteopontin Mediates Hyperbaric Oxygen Preconditioning-Induced Neuroprotection Against Ischemic Stroke
Abstract Neurosurgical operations may result in surgical injury which would lead to postoperative neurological deficits. Hyperbaric oxygen preconditioning (HBO-PC) may be beneficial for such people. However, the exact mechanism underlying HBO-PC is not well known yet. The aim of this study is to explore the role of osteopontin (OPN) in HBO-PC-induced neuroprotection. The study consisted of two experiments. In experiment 1, Sprague Dawley (SD) rats were divided into four groups: sham group, HBO-PC sham group, stroke group, and HBO-PC group (HBO-PC + stroke). The animals in the second experiment were randomly a...
Source: Molecular Neurobiology - July 21, 2015 Category: Neurology Source Type: research

Hyperbaric oxygen in patients with ischemic stroke following cardiac surgery: a retrospective observational trial.
CONCLUSIONS: HBO2₂ therapy was associated with significant improvement in patients with acute neurological deficits due to ischemic stroke following cardiac surgery. Though this fact suggests gas embolism as the most likely cause of stroke in this collective, other underlying pathologies cannot be ruled out. Randomized studies are needed for further evaluation. PMID: 29116691 [PubMed - in process]
Source: Undersea and Hyperbaric Medicine - September 1, 2017 Category: Sports Medicine Authors: Weixler VH, Yates AE, Puchinger M, Zirngast B, Pondorfer P, Ratzenhofer-Komenda B, Amegah-Sakotnik A, Smolle-Juettner FM, Dapunt O Tags: Undersea Hyperb Med Source Type: research

Hyperbaric oxygen for neurologic indications. Action plan for multicenter trials in: stroke, traumatic brain injury, radiation encephalopathy and status migrainosus
Publication date: September–October 2012 Source:Pediatria Polska, Volume 87, Issue 5 Author(s): Harry T. Whelan , Ann K. Helms Introduction: There is great interest in using hyperbaric oxygen (HBO) to treat neurological disease. The exquisite sensitivity of neural tissue to hypoxia makes increased oxygenation attractive as a therapy for disease processes that induce ischemia, edema, and, more recently, apoptosis. Four things specifically exist as targets for future projects and clinical trials: (1) stroke (2) traumatic brain injury (3) radiation induced necrosis and (4) status migrainosus. Methods: Specific aims: Strok...
Source: Pediatria Polska - November 6, 2014 Category: Pediatrics Source Type: research

Hyperbaric oxygen and focused rehabilitation program: a feasibility study in improving upper limb motor function after stroke
Applied Physiology, Nutrition, and Metabolism, Ahead of Print. Neuroplasticity and recovery after stroke can be enhanced by a rehabilitation program pertinent to upper limb motor function exercise and mental imagery (EMI) as well as hyperbaric oxygen therapy (HBOT). We assessed feasibility and safety of the combined approach utilizing both HBOT and EMI, and to derive preliminary estimates of its efficacy. In this randomized controlled trial, 27 patients with upper extremity hemiparesis at 3 –48 months after stroke were randomized to receive either a complementary rehabilitation program of HBOT-EMI (intervention group), o...
Source: Applied Physiology, Nutrition, and Metabolism - June 23, 2020 Category: Physiology Authors: S. Schiavo D. Richardson D. Santa Mina S. Buryk-Iggers J. Uehling J. Carroll H. Clarke C. Djaiani M. Gershinsky R. Katznelson Source Type: research

Early hyperbaric oxygen therapy may improve the long term neurological consequences of diabetic patients suffering from hemorrhagic stroke
Conclusions In this study, early HBOT was found to be safe and effective with regards to the long term neurological consequences of diabetic patients suffering from ICH.
Source: Neuroscience Letters - February 27, 2017 Category: Neuroscience Source Type: research

Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD+/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats Basic Sciences
Conclusions—HBO induced activation of ATP/nicotinamide adenine dinucleotide/silent mating type information regulation 2 homolog 1 pathway and protected blood–brain barrier in hyperglycemic middle cerebral artery occlusion rats. HBO might be promising approach for treatment of acute ischemic stroke patients, especially patients with diabetes mellitus or treated with r-tPA (recombinant tissue-type plasminogen activator).
Source: Stroke - May 22, 2017 Category: Neurology Authors: Qin Hu, Anatol Manaenko, Hetao Bian, Zongduo Guo, Jun-Long Huang, Zhen-Ni Guo, Peng Yang, Jiping Tang, John H. Zhang Tags: Animal Models of Human Disease, Basic Science Research, Ischemia, Neuroprotectants Original Contributions Source Type: research

Hyperbaric oxygenation and 20 ‐hydroxyeicosatetreanoic acid inhibition reduce stroke volume in female diabetic Sprague–Dawley rats
New Findings What is the central question of this study? Is there a beneficial effect and what are the mechanisms of acute and multiple hyperbaric oxygenation (HBO2) exposures on the outcome of cerebral tissue injury induced by a transient middle cerebral artery occlusion model in diabetic female rats? Are 20‐hydroxyeicosatetreanoic acid and epoxyeicosatrienoic acids involved? What is the main finding and its importance? Equal reduction of cortical and total infarct size in rats treated with HBO2 and HET0016 (20‐hydroxyeicosatetreanoic acid production inhibitor) and significant mRNA upregulation of epoxyeicosatrienoic...
Source: Experimental Physiology - November 2, 2017 Category: Physiology Authors: Mihael Mi šir, Marija Renić, Sanja Novak, Martina Mihalj, Anita Ćosić, Monika Vesel, Ines Drenjančević Tags: Research Paper Source Type: research

The Effect of Hyperbaric Oxygen Therapy on Functional Impairments Caused by Ischemic Stroke.
Conclusions: Findings from this study support the idea of HBOT as a potential intervention following stroke. PMID: 30402285 [PubMed]
Source: Neurology Research International - November 9, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research