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Molecules, Vol. 28, Pages 3802: Essential and Potentially Toxic Elements (PTEs) Content in European Tea (Camellia sinensis) Leaves: Risk Assessment for Consumers
ni Truzzi Tea (Camellia sinensis) is the second most consumed beverage worldwide, playing a key role in the human diet. Tea is considered a healthy drink, as its consumption has been linked to a lower risk of cardiovascular disease-related events and death, stroke, metabolic syndrome and obesity. However, several studies have shown that C. sinensis is a hyperaccumulator of Al and other elements that are considered potentially toxic. In the present study, the contents of 15 elements (both essential and toxic) were determined for the first time in tea leaves collected in tea gardens located in six different European c...
Source: Molecules - April 28, 2023 Category: Chemistry Authors: Girolametti Annibaldi Illuminati Damiani Carloni Truzzi Tags: Article Source Type: research

An undefined cystatin CsCPI1 from tea plant Camellia sinensis harbors antithrombotic activity
Biomed Pharmacother. 2023 Jan 25;159:114285. doi: 10.1016/j.biopha.2023.114285. Online ahead of print.ABSTRACTTea consumption has been linked to a decreased risk of cardiovascular disease (CVD) mortality, which imposes a heavy burden on the healthcare system; however, which components in tea cause this beneficial effect is not fully understood. Here we uncovered a cystatin (namely CsCPI1), which is a cysteine proteinase inhibitor (CPI) of the tea plant (Camellia sinensis) that promotes antithrombotic activity. Since thrombosis is a common pathogenesis of fatal CVDs, we investigated the effects of CsCPI1, which showed good ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - January 27, 2023 Category: Drugs & Pharmacology Authors: Mingqian Fang Jong-Ho Cha Hao-Ching Wang Peng Ye Bi Chen Mengrou Chen Wen-Hao Yang Xiuwen Yan Source Type: research

Drinking Black Tea May Lower Mortality Risk, Study Suggests
While green tea has a long-standing reputation for health benefits, research has been much more mixed on black tea. One problem, says Maki Inoue-Choi, an epidemiologist at the National Cancer Institute, is that large observational studies on tea and mortality have focused on countries like Japan or China—places where green tea is more popular. To fill this gap, Inoue-Choi and her colleagues analyzed data in the United Kingdom, where black tea drinking is common. After surveying about 500,000 people and following them for a median of 11 years, the results, published Aug. 29 in the journal Annals of Internal Medicine, ...
Source: TIME: Health - August 29, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized Diet & Nutrition healthscienceclimate Source Type: news

Tea consumption and cerebral hemorrhage risk: a meta-analysis
ConclusionsThis study suggests that daily tea consumption is related to a lower risk of cerebral hemorrhage among adults. Green tea consumption appears to be more beneficial in preventing cerebral hemorrhage. Physical activity, fruit/vegetables, and alcohol may affect the relationship between tea consumption and hemorrhagic stroke. Future studies should investigate the interplay of tea with these factors.
Source: Acta Neurologica Belgica - May 28, 2022 Category: Neurology Source Type: research

Tea intake and cardiovascular disease: an umbrella review
Ann Med. 2021 Dec;53(1):929-944. doi: 10.1080/07853890.2021.1933164.ABSTRACTBrewed tea (Camellia sinensis) is a major dietary source of flavonoids, in particular flavan-3-ols. Tea consumption has been suggested to be inversely associated with a decreased risk of cardiovascular disease (CVD). Several biological mechanisms support the inverse relationship between tea flavonoid intake and CVD risk. Given the recent accumulating evidence from various systematic reviews regarding the role of tea as a beverage in reducing CVD risk and severity, we conducted an umbrella review to describe and critically evaluate the totality of e...
Source: Annals of Medicine - August 16, 2021 Category: Internal Medicine Authors: Abby Keller Taylor C Wallace Source Type: research

Non-alcoholic beverages intake and risk of cardiovascular disease among Japanese men and women: the JPHC study
In conclusion, the risks of stroke and total cardiovascular disease were lower with a higher intake of non-alcoholic beverages in Japanese men and women.PMID:34284829 | DOI:10.1017/S0007114521002737
Source: The British Journal of Nutrition - July 21, 2021 Category: Nutrition Authors: Renzhe Cui Hiroyasu Iso Ehab S Eshak Koutatsu Maruyama Junko Ishihara Ribeka Takachi Norie Sawada Shoichiro Tsugane JPHC Study Group Source Type: research

Green Tea, Coffee Tied to Lower Mortality for Stroke, Myocardial Infarction Survivors Green Tea, Coffee Tied to Lower Mortality for Stroke, Myocardial Infarction Survivors
Green tea and coffee drinkers who survive a stroke or myocardial infarction have lower all-cause mortality risk than people who don ' t consume these beverages, a recent study suggests.Reuters Health Information
Source: Medscape Medical News Headlines - February 18, 2021 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Green Tea Consumption Improves Prognosis for Stroke, MI Survivors
THURSDAY, Feb. 4, 2021 -- For stroke and myocardial infarction (MI) survivors, green tea consumption is associated with improved prognosis, according to a study published online Feb. 4 in Stroke. Masayuki Teramoto, M.D., from the Osaka University...
Source: Drugs.com - Pharma News - February 4, 2021 Category: Pharmaceuticals Source Type: news

Protective Effect of Epigallocatechin Gallate on Endothelial Disorders in Atherosclerosis
Abstract: Healthy vascular endothelial cells regulate vascular tone and permeability, prevent vessel wall inflammation, enhance thromboresistance, and contribute to general vascular health. Furthermore, they perform important functions including the production of vasoactive substances such as nitric oxide (NO) and endothelium-derived hyperpolarizing factors, as well as the regulation of smooth muscle cell functions. Conversely, vascular endothelial dysfunction leads to atherosclerosis, thereby enhancing the risk of stroke, myocardial infarction, and other cardiovascular diseases (CVDs). Observational studies and randomiz...
Source: Journal of Cardiovascular Pharmacology - April 1, 2020 Category: Cardiology Tags: Review Article Source Type: research

Study: Drinking Tea May Help You Live Longer, Especially If It ’ s Green
This study strengthens the body of evidence that habitual tea drinking is associated with lower rates of atherosclerotic cardiovascular disease, though it cannot prove that it’s definitely the tea that’s responsible,” Dr. Jenna Macciochi, a lecturer in immunology at the University of Sussex, told the SMC. However, she noted that “a body of evidence in nutrition suggests that whole diet patterns are more informative of diet-disease relationships than any isolated food or nutrient.” Dr. Duane Mellor, a registered dietitian and senior teaching fellow at Aston Medical School, Aston University, sai...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 10, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN Green Tea Source Type: news

Tea consumption and risk of stroke in Chinese adults: a prospective cohort study of 0.5 million men and women.
CONCLUSIONS: Among Chinese adults, higher consumption of tea, especially green tea, was associated with a lower risk of ischemic and hemorrhagic stroke. PMID: 31711152 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - November 10, 2019 Category: Nutrition Authors: Tian T, Lv J, Jin G, Yu C, Guo Y, Bian Z, Yang L, Chen Y, Shen H, Chen Z, Hu Z, Li L, China Kadoorie Biobank Collaborative Group Tags: Am J Clin Nutr Source Type: research

Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer ’s Disease Through Activation of BDNF-TrkB Signaling Pathway
Conclusion The data in this manuscript demonstrates that apelin-13 upregulates BDNF against STZ-induced congnitive impairment by suppressing glial cell activity and inflammatory factors release. This suggests apelin signaling may be a new target in the treatment of AD. Ethics Statement All experimental protocols were carried out according to the National Institutes of Health Guide for the Care and Use of Laboratory Animals approved by the Central South University at XiangYa Animal Care and Use Committee. Author Contributions XqQ and LH conceived the study and contributed to its experimental design. HqL carried out the...
Source: Frontiers in Pharmacology - April 15, 2019 Category: Drugs & Pharmacology Source Type: research

Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases
Conclusion Activation of the Nrf2-dependent antioxidant system plays an important role in cell defense against oxidative stress damage, whereas the insufficiency of the Nrf2 system is associated with multiple aspects of the genesis and progression of metabolic diseases, posing a great risk to the cardiovascular system (Figure 1). The systemic increase of Nrf2 activity by several activators may be beneficial in the treatment of metabolic diseases. In addition, selective upregulation of Nrf2 genes may represent a potential therapy in obesity, diabetes and atherosclerosis. Looking to the future, experimental research that el...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research