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Total 1846 results found since Jan 2013.

Abstract P452: Evaluation of Pathological Basis of a Shrsp-based Congenic Strain Characterized by Early Stroke Occurrence Session Title: Hypertension and Aging and Cerebrovascular Disease and Stroke
Objectives: The stroke-prone spontaneously hypertensive rat (SHRSP) is a well-known model for essential hypertension and cerebral stroke. In the previous studies, we have identified a major blood pressure (BP) QTL on chromosome (chr) 1 of SHRSP and have explored gene(s) on the BP QTL responsible for hypertensive phenotypes of this strain through physiological analyses using reciprocal congenic strains between SHRSP and a normotensive control (Wistar-Kyoto rat, WKY). In a recent observation, we unexpectedly found that a SHRSP-based congenic strain, harboring a 0.3-Mbp fragment of the chr1 QTL, has developed stroke earlier t...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Hiroki Ohara, Davis L Ngarashi, Toru Nabika Tags: Poster Abstract Presentations Source Type: research

Attenuation of Myeloid Specific TGF β Signaling Induces Inflammatory Cerebrovascular Disease and Stroke.
Conclusions: Our studies show that TGFβ signaling in myeloid cells is required for maintenance of vascular health, and provide insight into inflammation-mediated cerebrovascular disease and stroke. PMID: 29051340 [PubMed - as supplied by publisher]
Source: Circulation Research - October 19, 2017 Category: Cardiology Authors: Hollander MC, Latour LL, Yang D, Ishii H, Xiao Z, Min Y, Ray-Choudhury A, Munasinghe J, Merchant AS, Lin PC, Hallenbeck J, Boehm M, Yang L Tags: Circ Res Source Type: research

Adipose tissue fatty acids present in dairy fat and risk of stroke: the Danish Diet, Cancer and Health cohort
ConclusionsOur results suggest that a larger percentage in adipose tissue of fatty acids for which dairy products are a major source is associated with a lower rate of ischemic stroke.
Source: European Journal of Nutrition - January 12, 2018 Category: Nutrition Source Type: research

Cluster Enrollment: A Screening Tool for Stroke Risk Factors in Minority Women Caregivers.
CONCLUSIONS: Using cluster enrollment, we discovered minority female caregivers were more likely to have unknown or poorly controlled vascular risk factors compared to stroke patients. Innovative health screening tools may benefit the extended family of minority patients participating in clinical trials. PMID: 30442422 [PubMed - as supplied by publisher]
Source: Journal of the National Medical Association - November 19, 2018 Category: General Medicine Tags: J Natl Med Assoc Source Type: research

Fluid and energy intake in stroke patients during acute hospitalization in a stroke unit
Publication date: Available online 14 January 2019Source: Journal of Clinical NeuroscienceAuthor(s): Alex Buoite Stella, Marina Gaio, Giovanni Furlanis, Pauline Douglas, Marcello Naccarato, Paolo ManganottiAbstractProper hydration and nutrition have been found to be contributing factors to a better recovery in patients after stroke. A better knowledge of factors influencing fluid and energy intake may contribute to a better care of the acute stroke patient. Aim of this study was to describe hydration status, fluid intake, and energy intake of stroke patients during acute hospitalization in a stroke unit. A retrospective de...
Source: Journal of Clinical Neuroscience - January 15, 2019 Category: Neuroscience Source Type: research

A New Study Suggests Vegetarians and Vegans Are at Higher Risk of Stroke. But Don ’t Reach for That Steak Just Yet
Vegetarians and vegans are likely to be concerned by the results of a new study with a surprising finding: those following meat-free diets, which are typically associated with better cardiovascular health, may actually have a higher risk of stroke than those who eat meat. But it’s too soon to run out and order a steak. The paper, published in the BMJ, found only a small increase in the risk of stroke, while confirming findings in other studies that vegetarians and vegans may have a lower risk of heart disease than meat-eaters. “It’s important to emphasize that we’ve looked at two outcomes here,R...
Source: TIME: Health - September 5, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition onetime Source Type: news

Characteristics of Cerebral Stroke in the Tibet Autonomous Region of China.
This article focuses on epidemiology features, risk factors, and pathogenesis of stroke in the TAR in an effort to generate a better understanding of the characteristics of stroke in this region. The special plateau-related factors such as its high elevation, limited oxygen, the high incidence of hypertension, smoking, and the unique dietary habits of the region are correlated with the high incidence of stroke. In addition to these factors, the pathogenesis of stroke in this high-altitude area is also unique. However, there is no established explanation for the unique occurrence and high incidence of stroke in the TAR. Our...
Source: Medical Science Monitor - January 11, 2020 Category: Research Tags: Med Sci Monit Source Type: research

Substitutions between potatoes and other vegetables and risk of ischemic stroke
ConclusionReplacing potatoes with fruiting vegetables was associated with a lower risk of ischemic stroke.
Source: European Journal of Nutrition - April 8, 2020 Category: Nutrition Source Type: research

The experiences of Indian people living in New Zealand with stroke.
CONCLUSION: All participants felt well looked after within the New Zealand healthcare context but highlighted the need for long term support. Self-management strategies participants considered important included changes to their diet, acceptance by oneself and society, returning to work, the role of family, and the use of technology and social media. Health professionals should consider these factors when providing self-management support to individuals of Indian ethnicity. IMPLICATIONS FOR REHABILITATION Advice and help around diet, lifestyle, and return to work were important priorities identified by our Indian stroke su...
Source: Disability and Rehabilitation - February 4, 2021 Category: Rehabilitation Authors: Singh P, Jayakaran P, Mani R, Hale L Tags: Disabil Rehabil Source Type: research

The endogenous and exogenous brain-derived neurotrophic factor plays pivotal roles in the pathogenesis of stroke onset in high salt-loaded hypertensive rats.
Abstract Brain-derived neurotrophic factor (BDNF) is known to have neuroprotective effects on multiple neurovascular diseases especially poststroke recovery. On the other hand, BDNF reported to increase blood pressure (BP) which is one of the major risk factor for stroke onset. To clarify the conflicting effects on stroke onset, we examined the expression of endogenous BDNF in relation to stroke onset. In addition, we explored the effect of exogenous central BDNF against stroke onset and all-cause mortality as the primary endpoint and BP as the secondary object in hypertensive rats with high-salt diet. In experime...
Source: Experimental Gerontology - February 17, 2021 Category: Geriatrics Authors: Hasegawa Y, Takemoto Y, Hayashi K, Kameno K, Kim-Mitsuyama S Tags: Exp Gerontol Source Type: research

NmFGF1-Regulated Glucolipid Metabolism and Angiogenesis Improves Functional Recovery in a Mouse Model of Diabetic Stroke and Acts via the AMPK Signaling Pathway
Diabetes increases the risk of stroke, exacerbates neurological deficits, and increases mortality. Non-mitogenic fibroblast growth factor 1 (nmFGF1) is a powerful neuroprotective factor that is also regarded as a metabolic regulator. The present study aimed to investigate the effect of nmFGF1 on the improvement of functional recovery in a mouse model of type 2 diabetic (T2D) stroke. We established a mouse model of T2D stroke by photothrombosis in mice that were fed a high-fat diet and injected with streptozotocin (STZ). We found that nmFGF1 reduced the size of the infarct and attenuated neurobehavioral deficits in our mous...
Source: Frontiers in Pharmacology - May 7, 2021 Category: Drugs & Pharmacology Source Type: research

Urinary cadmium and stroke - a case-cohort study in Danish never-smokers
CONCLUSIONS: Our results do not support that low levels of cadmium exposure among never-smokers are strongly associated with risk of stroke, although results varied somewhat by sex and method of accounting for urinary dilution.PMID:34062200 | DOI:10.1016/j.envres.2021.111394
Source: Environmental Research - June 1, 2021 Category: Environmental Health Authors: Aslak Harbo Poulsen Clara G Sears James Harrington Chanelle J Howe Katherine A James Nina Roswall Kim Overvad Anne Tj ønneland Gregory A Wellenius Jaymie Meliker Ole Raaschou-Nielsen Source Type: research

Correlation between dietary selenium intake and stroke in the National Health and Nutrition Examination Survey 2003-2018
CONCLUSIONS: Dietary selenium had a negative and non-linear correlation with the risk of stroke in adults. The correlation varied across different population subgroups.KEY MESSAGESDietary selenium had a negative and non-linear correlation with the risk of stroke in adults.Non-linear negative correlation trends were observed in subpopulations of females, age <60 years, poverty-income ratio <2.14, overweight and obesity, hypertension, non-diabetes, and non-anaemia.Dietary selenium intake of approximately 105 μg per day has an optimum effect on stroke.PMID:35594240 | DOI:10.1080/07853890.2022.2058079
Source: Annals of Medicine - May 20, 2022 Category: Internal Medicine Authors: Wenrui Shi Liang Su Jian Wang Fangze Wang Xu Liu Jianxin Dou Source Type: research