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Total 33 results found since Jan 2013.

Significance of Periclot MMP-9 in Ischemic Stroke Patients Undergoing Intra-arterial Interventions (P4.303)
CONCLUSIONS: Decreased periclot MMP-9 may be predictive of HT after ischemic stroke, contrasting with previous work demonstrating elevated peripheral MMP-9 as predictive of HT. Increased periclot MCP-4 and angiogenin expression, as well as decreased numbers of circulating monocytes, may serve as additional predictive markers of HT. Future work should measure the activity of periclot MMP-9. Study Supported by: Shimojani, LLC and NIH (DJ).Disclosure: Dr. Song has nothing to disclose. Dr. Prager has nothing to disclose. Dr. Brennan has nothing to disclose. Dr. Uchino has nothing to disclose. Dr. Hussain has nothing to disclos...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Song, A., Prager, B., Brennan, C., Uchino, K., Hussain, M., Rasmussen, P., Janigro, D. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Interventional Treatment for Ischemic Stroke Source Type: research

Quality Improvement Project: Improving the Time To Treatment in Inpatient Acute Ischemic Stroke (P7.130)
Conclusion/Proposal: In the inpatient setting there was a significant delay in the time to CT-scan and to t-PA; the main source of delay was time to CT-scan. There are many possible reasons for the delay: location of the CT-scanner, unfamiliarity with strokes by non-neurology staff, ready availability of t-PA. We proposed to target house staff education and t-PA availability. We developed a "stroke-code" checklist to be distributed to house staff from different services after a small explanatory lecture. We also developed an order form to create a zero wait time for t-PA, allowing the RN/PCA to be the first one served in t...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Liang, J., Garcia Santibanez, R., Walker, A., Boniece, I. Tags: Cerebrovascular Disease and Interventional Neurology: Barriers and Opportunities in Acute Stroke Treatment Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis
Conclusion Our data suggest that women who suffer from IS present with a poorer functional outcome than men at 3-months, regardless of other preclinical and clinical factors during the acute phase. These relationships seem to be mediated by atrial dysfunction and inflammation. The inflammatory response is slightly higher in women; however, there are no sex differences in their functional behavior. There is a probable relationship between the molecular marker of atrial dysfunction NT-proBNP and worse functional outcome in women, and the connection seems to be more important in cardioembolic stroke patients. In patients wi...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

A Genetic Variant of miR-34a Contributes to Susceptibility of Ischemic Stroke Among Chinese Population
This study was supported by National Natural Science Foundation of China (Nos. 81560552, 81260234), Natural Science Foundation of Guangxi Zhuang Autonomous Region (CN) (2017JJA180826), Innovation Project of Guangxi Graduate Education (CN) (201601009) and Key Laboratory Open Project Fund of Guangxi Zhuang Autonomous Region (CN) (kfkt20160064). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be fou...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Status epilepticus mimicking stroke recurrence.
CONCLUSION: Status epilepticus is not infrequent in patients with previous stroke and may present with negative neurological symptoms, thus mimicking a stroke recurrence. EEG should be considered as a potential diagnostic tool in the acute stroke setting, at least in patients with previous stroke. This article is part of the Special Issue "Seizures & Stroke". PMID: 31629647 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - October 15, 2019 Category: Neurology Authors: Pauletto G, Bax F, Gigli GL, Lorenzut S, Verriello L, Corazza E, Valente M Tags: Epilepsy Behav Source Type: research

Status epilepticus mimicking stroke recurrence
This article is part of the Special Issue “Seizures & Stroke”
Source: Epilepsy and Behavior - October 17, 2019 Category: Neurology Source Type: research

I Never Thought Stroke Would Happen to Me
by Myra Wilson, Stroke Survivor On November 3, 2014, I was in nursing school working as a student nurse at a hospital in Seattle. My first sign that something was not quite right was when I was walking through the nursing station and both of my eyes went blurry. I could still see color but I couldn't see letters. It was blurry for about 30 seconds before clearing up again. I was going to lunch and went to give a report to another nurse. The nurse noticed while I was speaking that I slurred my speech. I didn't notice my speech was slurred at all. It was at that time that I experienced a sudden sharp pain on the right s...
Source: Healthy Living - The Huffington Post - May 13, 2016 Category: Consumer Health News Source Type: news

Assessment of healthcare personnel knowledge of stroke care at a large referral hospital in sub-Saharan Africa – A survey based approach
Publication date: August 2017 Source:Journal of Clinical Neuroscience, Volume 42 Author(s): Chen Lin, Ravi Vakani, Peter Kussin, Mary Guhwe, Alfredo E. Farjat, Kingshuk Choudhury, David Renner, Chrispine Oduor, Carmelo Graffagnino There is no published literature regarding sub-Saharan health-care providers’ understanding of stroke management patterns. Understanding current stroke management knowledge is important in formulating future education opportunities for providers to optimize patient outcomes. A cross-sectional survey of acute stroke diagnosis, hospital management, and secondary prevention questions was administ...
Source: Journal of Clinical Neuroscience - June 29, 2017 Category: Neuroscience Source Type: research

Endovascular Stroke Therapy Results Improve over Time: The ‘Learning Curve' at a New Comprehensive Stoke Center
Conclusions: At a new community-based CSC, improved outcome occurred from year 1 to year 2, and trends towards decreased mortality, fewer complications, and improved revascularization were observed. Furthermore, the data shows that improvement in NIHSS score after EST is associated with decreased mortality following stroke in this setting, implying a net benefit.Cerebrovasc Dis Extra 2014;4:235-242
Source: Cerebrovascular Diseases Extra - January 13, 2015 Category: Neurology Source Type: research

Risk factors for perioperative ischemic stroke in cardiac surgery
Conclusion:Risk factors for ischemic stroke were carotid stenosis of 70% or more, diabetes on insulin and peripheral arteriopathy.ResumoObjetivo:O objetivo do presente trabalho foi avaliar os fatores de risco para acidente vascular encefálico isquêmico em pacientes submetidos à cirurgia cardíaca.Métodos:Entre janeiro de 2010 e dezembro de 2012, foram analisados prospectivamente 519 pacientes consecutivos submetidos à cirurgia cardíaca. A amostra foi dividida em dois grupos: os pacientes com acidente vascular encefálico isquêmico (AVEi) trans e pós-operatório foram alocados no grupo GAVEi (n=22) e os demais pacie...
Source: Revista Brasileira de Cirurgia Cardiovascular - August 25, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Variability in the use of neuroimaging techniques for diagnosis and follow-up of stroke patients
Publication date: Available online 14 January 2019Source: Neurología (English Edition)Author(s): C. Valcárcel-Nazco, D. Alonso-Modino, F. Montón-Álvarez, R. Sabatel-Hernández, M.S. Pastor-Santoveña, P. Mesa-Blanco, J.C. López-Fernández, P. Serrano-AguilarAbstractIntroduction and objectiveImaging diagnosis is essential for treatment planning in stroke patients. However, use of these techniques varies due to uncertainty about their effectiveness. Our purpose was to describe the use of CT and MRI in stroke and transient ischaemic attack (TIA) over 5 years in hospitals belonging to the Canary Islands Health Service and...
Source: Neurologia - January 15, 2019 Category: Neurology Source Type: research

O-007 Recanalization and Outcome Comparisons in Acute Ischemic Stroke Patients Treated with Mechanical Thrombectomy Selected by CT/MR Perfusion Imaging Versus CT Angiography
ConclusionsMechanical thrombectomy patients selected by CTA or perfusion imaging demonstrated no difference in successful recanalization rate, but higher level of recanalization/reperfusion and a trend of improved outcomes with CTA selection that may be attributed to improved treatment times.DisclosuresA. Honarmand: None. A. Shaibani: None. M. Hurley: None. P. Golnari: None. M. Potts: None. B. Jahromi: None. S. Ansari: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Honarmand, A., Shaibani, A., Hurley, M., Golnari, P., Potts, M., Jahromi, B., Ansari, S. Tags: Oral abstracts Source Type: research

Combination of Dexmedetomidine and Ketamine for Magnetic Resonance Imaging Sedation
Conclusions: The efficacy of DEX–KET sedation was comparable to that of midazolam for MRI examination. DEX–KET was related to shorter scan time and lower occurrence of complications compared to midazolam. Introduction Neurocritically ill patients often require brain magnetic resonance imaging (MRI) in addition to conventional neurological evaluations. Brain MRI can reveal structural lesions with a high sensitivity due to its excellent spatial resolution and enhanced soft tissue contrast (1–3). To acquire MRI images, patients' cooperation is imperative. However, keeping patients with ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Sex Differences in Sex Hormone Profiles and Prediction of Consciousness Recovery After Severe Traumatic Brain Injury
Conclusion: These findings indicate that TBI differentially affects the levels of sex-steroid hormones in men and women patients. Plasma levels of testosterone could be a good candidate blood marker to predict recovery from unconsciousness after sTBI for male patients. Introduction Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is increasing in incidence (1). Patients with acute severe TBI (sTBI) often develop severe disorders of consciousness, i.e., coma, minimally conscious state or vegetative state. Although many patients may regain consciousness during the 1-month post-TBI p...
Source: Frontiers in Endocrinology - April 25, 2019 Category: Endocrinology Source Type: research