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Total 42 results found since Jan 2013.

Finding Power in My Panic Attacks
Trouble started in the form of rivulets of sweat dampening the waistband of my underwear. It was a bluebird afternoon in Phoenix in December of 2020, mid 60s, desert dry, and my heart was jackhammering against my ribcage. Breathing felt like I was sucking air through a stir straw. A small ABC News crew was arrayed before me, ready to broadcast the report I’d written that day, but with my vision narrowed to a needle’s eye, I could barely see them. I tried to swallow away the sandiness in my mouth but realized I’d forgotten how. [time-brightcove not-tgx=”true”] “I can’t swallow!...
Source: TIME: Health - September 12, 2023 Category: Consumer Health News Authors: Matt Gutman Tags: Uncategorized freelance Source Type: news

P124/272 Initial encounter with a cutting-edge mobile head CT scanner (Somatom On.site) in a neuro-intensive care unit
ConclusionThe study demonstrates the clinical effectiveness of modern mobile CT scanners in neurointensive care units. The Somatom On.site provides sufficient image quality, saves time and supports timely decision making. The integration of mobile CT scanners in NICUs improves patient care and workflow. Prospective studies are needed to validate these findings and assess the long-term impact in NICUs and other units, such as stroke units.Disclosure of InterestCK serves as consultants for Acandis GmbH (Pforzheim, Germany) and proctor for MicroVention Inc./Sequent Medical (Aliso Viejo, CA, USA).
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Goertz, L., Al-Sewaidi, Y., Habib, M., Ranft, A., Kabbasch, C. Tags: 3.1 OTHER - Innovation Source Type: research

MRI for all: Cheap portable scanners aim to revolutionize medical imaging
.news-article__hero--featured .parallax__element{ object-position: 47% 50%; -o-object-position: 47% 50%; } The patient, a man in his 70s with a shock of silver hair, lies in the neuro intensive care unit (neuro ICU) at Yale New Haven Hospital. Looking at him, you’d never know that a few days earlier a tumor was removed from his pituitary gland. The operation didn’t leave a mark because, as is standard, surgeons reached the tumor through his nose. He chats cheerfully with a pair of research associates who have come to check his progress with a new and potentially revolutionary device they are testing. The cylind...
Source: Science of Aging Knowledge Environment - February 23, 2023 Category: Geriatrics Source Type: research

Carotid artery direct access for mechanical thrombectomy: the Carotid Artery Puncture Evaluation (CARE) study
Conclusion In this large multicentric study, DCP was scantly performed for vascular access to perform MT (0.39%) in patients with AIS-LVO and had a high rate of complications (18.5%). Our results provide arguments for not closing the cervical access by manual compression after MT.
Source: Journal of NeuroInterventional Surgery - November 14, 2022 Category: Neurosurgery Authors: Dumas, V., Kaesmacher, J., Ognard, J., Forestier, G., Dargazanli, C., Janot, K., Behme, D., Shotar, E., Chabert, E., Velasco, S., Bricout, N., Ben Hassen, W., Veunac, L., Geismar, M., Eugene, F., Detraz, L., Darcourt, J., L'Allinec, V., Eker, O. F., Conso Tags: Ischemic stroke Source Type: research

E-205 In vitro evaluation of full-length, mr-safe interventional passive catheter markers at 3T
ConclusionAlthough worst-case artifacts were observed at 90°, they remained acceptable for use in guide catheters. Additionally, 20-mm marker separation could provide distinct artifacts down the length of a catheter during MRI-guided interventions, despite anatomic tortuosity. The phantom used in this study was shallow, which limited the ability to distinguish between real artifacts and those arising from the solution-air interface. Hence, accuracy of the degree of increased artifact may warrant further investigation. This study simulated worst-case orientations in vitro; more data should be collected in vivo using rea...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Kilbride, B., Jordan, C., Ahn, S., Mueller, K., Chu, A., Barry, D., Moore, T., Martin, A., Wilson, M., Hetts, S. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Correlation of DTI-Derived Measures to Therapy-Mediated Recovery after Stroke: Preliminary Findings
Conclusion: Clinical and functional recovery after stroke is well-correlated with the DTI and BOLD parameters i.e., rFA ratios, CST involvement fiber numbers, and % signal intensity of the ipsilesional cortex.
Source: Neurology India - October 30, 2021 Category: Neurology Authors: Ashu Bhasin Padma Srivastava Senthil S Kumaran Source Type: research

Diagnostic reference levels and median doses for common clinical indications of CT: findings from an international registry
ConclusionsDRLs for CTDIvol and DLP for EUCLID clinical indications from diverse organizations were established and can contribute to dose optimization. These values were usually significantly higher in the US than in Europe.Key Points•Registry data were used to create benchmarks for 10 common indications for CT identified by the European Society of Radiology.•Observed US radiation doses were higher than European for 9 of 10 indications (except chronic sinusitis).•The presented diagnostic reference levels and median doses highlight potentially unnecessary variation in radiation dose.
Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research

Bedside point-of-care MRI appears convenient and accurate
Bedside use of point-of-care MRI is feasible and safe for neurological intensiv...Read more on AuntMinnie.comRelated Reading: Portable MRI is feasible for ICU neuroimaging German startup targets low-cost, portable MRI Hyperfine touts stroke study for portable MRI scanner Video from J.P. Morgan: Portable MRI takes to the streets
Source: AuntMinnie.com Headlines - May 17, 2021 Category: Radiology Source Type: news

Portable MRI is feasible for ICU neuroimaging
Use of a portable low-field MRI scanner is feasible for neuroimaging patients...Read more on AuntMinnie.comRelated Reading: Hyperfine gets clearance for point-of-care MRI German startup targets low-cost, portable MRI Hyperfine touts stroke study for portable MRI scanner Video from J.P. Morgan: Portable MRI takes to the streets Hyperfine partners with Nvidia, Penn Medicine on portable MRI system
Source: AuntMinnie.com Headlines - September 8, 2020 Category: Radiology Source Type: news

“Accent issue”: foreign accent syndrome following ischemic stroke
In conclusion, FAS is a rare motor speech disorder, often related to cerebrovascular accidents involving critical regions in the dominant hemisphere. In addition, the present case adds further evidence to the role of the left primary motor cortex in modulation of prosody. In rare cases FAS can be the only sign of stroke or can appear after recovery from post-stroke aphasia.
Source: Neurological Sciences - October 28, 2019 Category: Neurology Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota
Conclusion Collectively, pharmacokinetic and pharmacodynamic association studies provide evidence that the gut microbiota plays a vital role in the fate of crocin and crocetin in the gastrointestinal tract. In addition, the cross-interaction between gut microbiota and crocin might mediate the activation of the cerebral-protective effect of orally administered crocin. Ethics Statement This study was carried out in accordance with the recommendations of ‘Institutional Animal Research Committee guidelines, Animal Ethics Committee of China Pharmaceutical University.’ The protocol was approved by the ‘An...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Challenge to the Intestinal Mucosa During Sepsis
Conclusion The impact of sepsis on the gut is manifold, e.g., sepsis mediated alteration of the gut-blood barrier and increase in the intestinal permeability, which may correlate with the phenomena of bacterial translocation and lymphatic activation (“toxic-lymph”). Systemic consequences of sepsis are widespread and concern to the coagulative system, the microbiome as well as enzymes, such as pancreatic proteases, MMPs and IAPs. Nevertheless, the therapeutic approaches for modulating the mucosal immune system are still rarely effective in daily routine. Recent published studies showing that treatment with ...
Source: Frontiers in Immunology - April 29, 2019 Category: Allergy & Immunology Source Type: research

Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats
Conclusion Principal findings of this work are that abnormal Ca2+ transient amplitude, contractile dysfunction; and impaired relaxation of MetS cardiomyocytes underlies intrinsic dysfunctional RyR2 and SERCA pump. Abnormal activity of RyRs was evidenced by its decreased ability to bind [3H]-ryanodine. Although the MetS condition does not modify RyR2 protein expression, its phosphorylation at Ser2814 is decreased, which impairs its capacity for activation during ECC. The dysfunctional RyRs, together with a decreased activity of SERCA pump due to decreased Thr17-PLN phosphorylation suggest a downregulation of CaMKII in MetS...
Source: Frontiers in Physiology - April 29, 2019 Category: Physiology Source Type: research

Modulating Applied Task Performance via Transcranial Electrical Stimulation
Conclusion tES may prove valuable for modulating applied task performance, though research in this area warrants careful consideration of several individual-, context-, and task-related factors that may predict the robustness and directionality of tES effects. Whereas most applied research with tES has administered tDCS, tACS and tRNS have also shown potential to modulate cortical activity and behavior. Even in highly applied and dynamic tasks, such as navigation and driving, tES appears to carry some performance benefits. This is compelling because as tES is slowly incorporated into highly complex real-world environments...
Source: Frontiers in Human Neuroscience - April 29, 2019 Category: Neuroscience Source Type: research