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Total 7365 results found since Jan 2013.

Post-stroke depression: different characteristics based on follow-up stage and gender-a cohort perspective study from Mainland China.
CONCLUSION: PSD is common in stroke survivors, and female patients have higher prevalence of PSD. Risk factors for PSD in the acute phase are different from that in the chronic phase of stroke. Female gender is an independent risk factor for PSD in the acute stage of stroke. Smoking, frontal lobe lesion, and living alone are predictive factors for PSD in the chronic stage of stroke. NIHSS score is a risk factor for PSD both in the acute and in the chronic stage of stroke. Further studies are needed to understand the mechanisms underlying the elevated prevalence of PSD in female. PMID: 28828931 [PubMed - as supplied by publisher]
Source: Neurological Research - August 24, 2017 Category: Neurology Tags: Neurol Res Source Type: research

The associations of stroke, transient ischemic attack, and/or stroke-related recurrent vascular events with Lipoprotein-associated phospholipase A2: A systematic review and meta-analysis
Conclusions:In patients with TIA and first ischemic stroke, elevated Lp-PLA2 activity levels were associated with recurrent vascular events. And in the general population elevated Lp-PLA2 levels were associated with the risk of stroke, although the association between Lp-PLA2 activity levels and the risk of stroke was less profound compared with the corresponding association of stroke risk with the Lp-PLA2 mass levels. Background: Studies on stroke and lipoprotein-associated phospholipase A2 (Lp-PLA2) have produced conflicting results. Objective: The aim of the study was to assess the associations of Lp-PLA2 levels ...
Source: Medicine - December 1, 2017 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Association between Serum Copeptin and Stroke in Rural Areas of Northern China: A Matched Case-Control Study.
Conclusions: Elevated serum copeptin levels were positively associated with ischemic stroke and adversely associated with hemorrhagic stroke. Additional prospective studies with larger sample size are needed to confirm the present findings. PMID: 30402171 [PubMed - in process]
Source: Disease Markers - November 9, 2018 Category: Laboratory Medicine Tags: Dis Markers Source Type: research

Understandings stroke in rural Malaysia: ethnographic insights.
Conclusion: Lack of knowledge about stroke and its symptoms was evident in participants' account. Findings emphasize the importance of knowledge based health interventions, especially in health education strategies for stroke survivors to reduce delays to diagnosis and potentially improve health outcomes post-stroke. Implications for rehabilitation Stroke survivors often form explanatory models of stroke that draw from both biomedical and traditional explanations of stroke. Understanding how people derive lay understandings of stroke can contribute towards developing the goals and activities that facilitate recovery and re...
Source: Disability and Rehabilitation - June 5, 2019 Category: Rehabilitation Authors: Yap KH, Warren N, Allotey P, Reidpath DD Tags: Disabil Rehabil Source Type: research

Stroke History is an Independent Risk Factor for Poor Prognosis in Ischemic Stroke patients: Results from a Large Nationwide Stroke Registry.
CONCLUSION: After adjusting for the potential confounders, stroke history was still an independent risk factor for poor prognosis of ischemic stroke, which further emphasizes the importance of secondary prevention of ischemic stroke. The specific causes of poor prognosis in patients with history of stroke need to be furtherly investigated. PMID: 32807054 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - August 16, 2020 Category: Neurology Authors: Qin H, Wang P, Zhang R, Yu M, Zhang G, Liu G, Wang Y Tags: Curr Neurovasc Res Source Type: research

Perceived challenges in delivering comprehensive care for patients following stroke: a qualitative study of stroke care providers in Guangdong Province, China.
Conclusions: While comprehensive stroke care has become a priority in China, our study highlights some important gaps in the current provision of stroke care.IMPLICATIONS FOR REHABILITATIONComprehensive integrated stroke care is essential to maximize the effectiveness of stroke services and in China it needs to be further improved.Multidisciplinary stroke care systems should strengthen collaborations across all relevant disciplines and should include a clear role for registered nurses.Follow-up care after discharge needs more engagement with family caregivers. PMID: 32343635 [PubMed - as supplied by publisher]
Source: Disability and Rehabilitation - April 27, 2020 Category: Rehabilitation Authors: Wu C, Zou G, Chen M, Wan L, Kielmann K, McCormack B Tags: Disabil Rehabil Source Type: research

Persistence of drug therapy is associated with ischemic stroke and other vascular events in high-risk stroke population
The high-risk stroke populations are significantly associated with an increased risk of stroke or other vascular events. Although proven primary and secondary stroke prevention medications are available, persistent use is required to be effective. However, the persistence of drug therapy and its association with outcomes in the high-risk stroke population have received limited study in China. Hence, according to the China National Stroke Screening Survey (CNSSS) program in 2015, we performed this multicenter population-based cross-sectional survey and prospective cohort study in Sichuan of southwestern China. The residents...
Source: Frontiers in Neurology - July 25, 2022 Category: Neurology Source Type: research

Association of Homocysteine with Acute Stroke and Its Subtypes in the Chinese Population
CONCLUSION: Plasma Hcy levels were found to be positively correlated with the risk of stroke, particularly in the context of LAA, SAO stroke, and HICH. Additionally, Hcy levels demonstrated a positive correlation with stroke severity in patients presenting with SAO stroke. These findings suggest potential clinical implications in stroke prevention, particularly for ischemic stroke (LAA, SAO subtypes) and HICH by employing homocysteine-lowering therapies. Future investigations are warranted to fully elucidate these associations.PMID:37342757 | PMC:PMC10278861 | DOI:10.2147/NDT.S409591
Source: Atherosclerosis - June 21, 2023 Category: Cardiology Authors: Panpan Zhang Yurong Zhang Source Type: research

Prevalence, Incidence and Mortality of Stroke in China: Results from a Nationwide Population-Based Survey of 480,687 Adults.
CONCLUSIONS: -Stroke burden in China has increased over the last 30 years, and remains particularly high in rural areas. There is a north-to-south gradient in stroke in China, with the greatest stroke burden observed in the northern and central regions. PMID: 28052979 [PubMed - as supplied by publisher]
Source: Circulation - January 3, 2017 Category: Cardiology Authors: Wang W, Jiang B, Sun H, Ru X, Sun D, Wang L, Wang L, Jiang Y, Li Y, Wang Y, Chen Z, Wu S, Zhang Y, Wang D, Wang Y, Feigin VL, NESS-China investigators Tags: Circulation Source Type: research

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack.
CONCLUSIONS: Peroxisome proliferator-activated receptor gamma agonists probably reduce recurrent stroke and total events of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke, and may improve insulin sensitivity and the stabilisation of carotid plaques. Their effects on adverse events are uncertain. Our conclusions should be interpreted with caution considering the small number and the quality of the included studies. Further well-designed, double-blind RCTs with large samples are required to assess the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular...
Source: Cochrane Database of Systematic Reviews - December 2, 2017 Category: General Medicine Authors: Liu J, Wang LN Tags: Cochrane Database Syst Rev Source Type: research

The associations of lipids and lipid ratios with stroke: A prospective cohort study
In conclusion, TC/HDL‐C ratio may better predict stroke risk in men, whereas TG was more valuable in predicting stroke risk in women. TC/HDL‐C and TG may help to discriminate high stroke risk individuals and serve as potential targets for stroke prevention.
Source: The Journal of Clinical Hypertension - November 21, 2018 Category: Cardiology Authors: Xiaojuan Liu, Ling Yan, Fuzhong Xue Tags: ORIGINAL PAPER Source Type: research

Trends in the incidence of recurrent stroke at 5 years after the first-ever stroke in rural China: a population-based stroke surveillance from 1992 to 2017.
Abstract Recent data on the incidence and trends for recurrent strokes in China are scarce. We assessed the temporal trends in recurrent stroke incidence using in rural China. The age-standardized incidences of recurrent stroke, within 5 years of the incident stroke event, were estimated for 3 time periods: 1992-1998, 1999-2005, and 2006-2012. Among the 768 documented incident stroke cases, 26.3% of the patients experienced recurrent stroke within 5 years. The overall age-adjusted recurrent stroke incidence was 43.93 per 100,000 person-years (1992-2012). During the 2006-2012 period, the recurrent stroke incidence ...
Source: Aging - March 18, 2019 Category: Biomedical Science Authors: Zhao W, Wu J, Liu J, Wu Y, Ni J, Gu H, Tu J, Wang J, An Z, Ning X Tags: Aging (Albany NY) Source Type: research

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack.
CONCLUSIONS: Peroxisome proliferator-activated receptor gamma agonists probably reduce recurrent stroke and total events of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke, and may improve insulin sensitivity and the stabilisation of carotid plaques. Their effects on adverse events are uncertain. Our conclusions should be interpreted with caution considering the small number and the quality of the included studies. Further well-designed, double-blind RCTs with large samples are required to assess the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular...
Source: Cochrane Database of Systematic Reviews - October 8, 2019 Category: General Medicine Authors: Liu J, Wang LN Tags: Cochrane Database Syst Rev Source Type: research

Rate and Determinants of Recurrence at 1 Year and 5 Years After Stroke in a Low-Income Population in Rural China
Recurrent stroke is becoming an increasingly important public health issue owing to the increased risk of disability and death. However, population-based studies investigating the rate of recurrent stroke in China are rare. We explored the rate and determinants of recurrent stroke within 1 and 5 years after the initial stroke in a rural population in China. Data for stroke events were obtained from the Tianjin Brain Study, conducted between 1992 and 2016. The age-standardized rates of recurrent stroke within the first year and the first 5 years after the initial stroke were calculated for this period. Determinants of recur...
Source: Frontiers in Neurology - January 22, 2020 Category: Neurology Source Type: research

Predictive Value of Cystatin C for Stroke Recurrence in Patients With Acute Ischemic Stroke.
CONCLUSIONS: In ischemic stroke patients with high hsCRP concentrations, higher CysC concentrations increased the risk of stroke recurrence and vascular events. This indicates that the predictive value of CysC on stroke recurrence may depend on the inflammation status of patients. PMID: 33208593 [PubMed - as supplied by publisher]
Source: Circulation Journal - November 19, 2020 Category: Cardiology Authors: Liu H, Qian S, Zhong C, Wang A, Peng Y, Peng H, Xu T, Bu X, Xu T, Geng D, Zhang Y Tags: Circ J Source Type: research