Filtered By:
Procedure: Transplants
Nutrition: Organic

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 246 results found since Jan 2013.

Is fecal microbiota transplantation a useful therapeutic intervention for psychiatric disorders? A narrative review of clinical and preclinical evidence
Curr Med Res Opin. 2022 Sep 12:1-32. doi: 10.1080/03007995.2022.2124071. Online ahead of print.ABSTRACTThe therapeutic management of psychiatric disorders is currently confronted with a critical need to find new therapeutic interventions due to the high rates of non-responsivity or low responsivity in the key pathologies, e.g., schizophrenia spectrum disorders, alcohol use disorders, or major depressive disorder. The modulation of intestinal microbiota has been explored in various organic and psychiatric dysfunctions, with different degrees of success. However, this type of intervention may represent a helpful add-on at a ...
Source: Current Medical Research and Opinion - September 12, 2022 Category: Research Authors: Octavian Vasiliu Source Type: research

Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

The Impact of DNA Extraction Methods on Stool Bacterial and Fungal Microbiota Community Recovery
Conclusion Our understanding of the human gut microbiome role in health and disease depends on obtaining reliable and comparable microbial data of both bacterial and fungal communities. To achieve this goal, using an appropriate methodology is an important step. Previous efforts in standardizing methodology for bacterial microbiome research lead to the recommendation of using the IHMS protocol Q worldwide, to ensure data reproducibility and comparability. In this study, we evaluated and compared the impact of five different DNA extraction methods including the IHMS protocol Q, on the representation of fecal bacterial and ...
Source: Frontiers in Microbiology - April 16, 2019 Category: Microbiology Source Type: research

Trazodone for Insomnia: A Systematic Review
Conclusion. A review of the literature suggests that there are adequate data supporting the efficacy and general safety of the low-dose use of trazodone for the treatment of insomnia. keywords: insomnia, hypnotics, treatment, trazodone, sedative Keywords: insomnia, hypnotics, treatment, trazodone, sedative Innov Clin Neurosci. 2017;14(9–10):24–34 Introduction Insomnia is characterized by difficulty falling asleep, difficulty staying asleep, or waking too early1 and is associated with significant impairments in daytime activities, which might occur despite adequate opportunities for sleep.2–6 Primary insomnia is an or...
Source: Innovations in Clinical Neuroscience - July 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review hypnotics insomnia sedative trazodone treatment Source Type: research

In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine
Conclusion: Overall, this study provides a high accurate approach to predict HILI and an in silico perspective into understanding the hepatotoxicity mechanism of TCM, which might facilitate the discovery and development of new drugs. Introduction Liver injury induced by drug, novel foods or phytotherapy, also known as hepatotoxicity, is still a major clinical and pharmaceutical concern (Amadi and Orisakwe, 2018; Hammann et al., 2018; Kyawzaw et al., 2018; Real et al., 2018). According to the data from United States National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), hepatotoxicity accounts for...
Source: Frontiers in Pharmacology - May 2, 2019 Category: Drugs & Pharmacology Source Type: research

Clinical Controversy in Transplantation: Tacrolimus Versus Cyclosporine in Statin Drug Interactions.
Conclusions: Clinicians need to be aware that tacrolimus and cyclosporine are not the same with regard to causing drug interactions with statins. Tacrolimus can be used with statins without the need for dose adjustments because of lack of an interaction. PMID: 31441337 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - August 22, 2019 Category: Drugs & Pharmacology Authors: Migliozzi DR, Asal NJ Tags: Ann Pharmacother Source Type: research

Hyponatremia in Children With Bacterial Meningitis
Conclusion: Hyponatremia occurred in 66.4% of the assessed pediatric bacterial meningitis patients. Moderate and severe hyponatremia affected the severity of pediatric bacterial meningitis. Only severe hyponatremia affected the short-term prognosis of patients with pediatric bacterial meningitis. We recommend that patients with pediatric bacterial meningitis who exhibit convulsions and increased blood glucose levels should be checked for severe hyponatremia. Further studies are needed to evaluate the effectiveness of treatment of hyponatremia. Introduction Hyponatremia, defined as a serum sodium concentration of �...
Source: Frontiers in Neurology - April 29, 2019 Category: Neurology Source Type: research

The Saliva Exposome for Monitoring of Individuals ’ Health Trajectories
Conclusions: Saliva contains molecular information worthy of interrogation via EWAS. The simplicity of specimen collection suggests that saliva offers a practical alternative to blood for measurements that can be used to characterize individual exposomes. https://doi.org/10.1289/EHP1011 Received: 23 August 2016 Revised: 08 November 2016 Accepted: 18 November 2016 Published: 20 July 2017 Address correspondence to V. Bessonneau, Silent Spring Institute, 320 Nevada St., Suite 302, Newton, Massachusetts 02460 USA. Telephone: (617) 332-4288. Email: vincent.bessonneau@gmail.com The authors declare they have no actual or po...
Source: EHP Research - July 20, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Source Type: research

Thermal disturbance of fertile soils to search for new biological control options in strawberry crops affected by yield decline
Publication date: Available online 29 July 2018Source: Biological ControlAuthor(s): L.M. Manici, F. Caputo, A. Rossi, A.R. Topp, M. Zago, M. KeldererAbstractA study aiming at investigating biological control agents for protecting strawberry during the post-transplant period was performed. For this purpose, a series of fertile soils, rich in organic matter, which had been subjected to intensive strawberry cultivation, were selected. Soil samples taken from those soils were subjected to thermal treatment (up to 80 °C) for a short time to induce microbial changes aiming at improving soil suppressiveness. A greenhouse growth ...
Source: Biological Control - July 29, 2018 Category: Biology Source Type: research

Adverse reactions on day zero of hematopoietic stem cell transplantation: integrative review.
CONCLUSION: The main adverse reactions identified in the studies were nausea and emesis. Those classified as mild and moderate were the most frequent in the studies that used the severity classification; and the cardiovascular, respiratory and gastrointestinal systems were the most affected in those that used the classification by organic systems. PMID: 30517435 [PubMed - in process]
Source: Revista gaucha de enfermagem EENFUFRGS - December 7, 2018 Category: Nursing Tags: Rev Gaucha Enferm Source Type: research

Manure and Doxycycline Affect the Bacterial Community and Its Resistome in Lettuce Rhizosphere and Bulk Soil
Conclusion The study revealed that the application of manure and manure spiked with doxycycline had a strong impact on the abundance and diversity of ARGs, MGEs, and the prokaryotic community structure, which was more pronounced in the bulk soil than in the rhizosphere of lettuce. This implies that the plant has an important role in modulating the effects and fate of manure-derived antibiotics and ARB, likely via the microbes selected in its rhizosphere by root exudation. Manure application led to a decreased relative abundance of Proteobacteria and Actinobacteria in bulk soil and rhizosphere, while that of Firmicutes inc...
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

CYC1, SDHA, UQCRC1, UQCRQ, and SDHB might be important biomarkers in kidney transplant rejection.
CONCLUSIONS: We reported several potential genes may be associated with the kidney transplant rejection, which should provide novel biomarkers for kidney transplant surveillance. PMID: 32302684 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Chemistry - April 13, 2020 Category: Chemistry Authors: Fan P, Zhang W, Liu Y Tags: Clin Chim Acta Source Type: research

Janssen Highlights Commitment to Advancing Transformative Innovations in Oncology with Scientific Updates from Deep, Diverse Pipeline and Portfolio at ASCO and EHA Virtual Scientific Programs
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 30 company-sponsored studies, including six oral presentations, will be featured during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, June 4-8. Janssen presentations will include new data and updates for both approved and investigational therapeutics that are being studied for the treatment of various solid tumors and blood cancers. Immediately following ASCO, additional data will be featured during the European Hematology Association (EHA) Virtual Congress, June 9-17. A comp...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Therapeutic oxygen delivery by perfluorocarbon-based colloids
Adv Colloid Interface Sci. 2021 May 1;294:102407. doi: 10.1016/j.cis.2021.102407. Online ahead of print.ABSTRACTAfter the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed untoward effects to the product, the development of perfluorocarbon (PFC)-based O2 nanoemulsions ("blood substitutes") has come to a low. Yet, significant further demonstrations of PFC O2-delivery efficacy have continuously been reported, such as relief of hypoxia after myocardial infarction or stroke; protection of vital organs during surg...
Source: Advances in Colloid and Interface Science - June 13, 2021 Category: Chemistry Authors: Marie Pierre Krafft Jean G Riess Source Type: research