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Infectious Disease: Outbreaks

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Saving lives, preventing health risks and restoring health care services in the aftermath of ...
Tripoli, Libya, 22 September 2023 – In the wake of catastrophic floods that had a devastating impact on Libya's east coast, the World Health Organization (WHO) is taking swift action to assist affected communities. WHO is supporting urgent efforts to restore access to health care and control the spread of infectious diseases, especially among the tens of thousands of people who have been displaced and are now living in shelters. “The magnitude of this catastrophe is staggering,” said Dr Ahmed Zouiten, WHO Representative in Libya. “The need for swift, unified action cannot be overstated. We are collaborating closel...
Source: WHO EMRO News - September 22, 2023 Category: Middle East Health Source Type: news

Gender Differences in Psychosocial Stress During the COVID-19 Pandemic: A Population-based Study in South Korea
CONCLUSIONS: The COVID-19 pandemic has exerted differential impacts on psychosocial stress among working-age individuals in South Korea, with women, particularly those in urban areas, experiencing a heightened risk. The findings highlight the importance of addressing gender-specific needs and implementing appropriate interventions to mitigate the psychosocial consequences of the pandemic.PMID:37735833 | DOI:10.3961/jpmph.23.170
Source: Journal of Preventive Medicine and Public Health - September 22, 2023 Category: International Medicine & Public Health Authors: Minku Kang Sarah Yu Seung-Ah Choe Daseul Moon Myung Ki Byung Chul Chun Source Type: research

Viruses, Vol. 15, Pages 1980: Animal Models for Henipavirus Research
olsey Hendra virus (HeV) and Nipah virus (NiV) are zoonotic paramyxoviruses in the genus Henipavirus (HNV) that emerged nearly thirty years ago. Outbreaks of HeV and NiV have led to severe respiratory disease and encephalitis in humans and animals characterized by a high mortality rate. Despite the grave threat HNVs pose to public health and global biosecurity, no approved medical countermeasures for human use currently exist against HeV or NiV. To develop candidate vaccines and therapeutics and advance the field’s understanding of HNV pathogenesis, animal models of HeV and NiV have been instrumental and ...
Source: Viruses - September 22, 2023 Category: Virology Authors: Declan D. Pigeaud Thomas W. Geisbert Courtney Woolsey Tags: Review Source Type: research

IJERPH, Vol. 20, Pages 6803: Demographic and Clinical Characteristics of Mpox Patients Attending an STD Clinic in Lisbon
ândida Fernandes Mpox is a viral disease caused by the monkeypox virus, which marked the year of 2022 with a global outbreak. While previously considered to be a zoonosis of almost exclusive animal-to-human transmission, the current outbreak has been attributed to human-to-human transmission, particularly sexual transmission. As a new sexually transmissible disease, we studied the epidemiological and clinical features, as well as the concomitant occurrence of other sexually transmissible diseases, treatment approach, and outcome of our 291 patients, in the current outbreak. We found a total of 169 concomitant sexually...
Source: International Journal of Environmental Research and Public Health - September 22, 2023 Category: Environmental Health Authors: Margarida Brito Caldeira Jos é Miguel Neves Mafalda Pestana Rita Corte-Real Maria Jos é Borrego Rita Cordeiro Jorge Machado Ana Pelerito Isabel Lopes De Carvalho Maria Sofia N úncio C ândida Fernandes Tags: Article Source Type: research

Impact of COVID-19 on the supply chain of essential health commodities: a mixed method study, in Dar es Salaam, Tanzania
ConclusionsCOVID-19 led to shortage, increased prices and delayed delivery of essential health commodities. This might happen in the future whenever unexpected crises causing disruption in the supply chain occur underscoring the need for the country preparedness measures.
Source: Journal of Pharmaceutical Policy and Practice - September 22, 2023 Category: Pharmaceuticals Source Type: research

News at a glance: Diphtheria vaccine shortage, prisoner release, and iNaturalist ’s growth
CONSERVATION Popular biodiversity app to expand The nonprofit that runs iNaturalist, a popular app and website for identifying species, has received a $10 million grant to expand. The funding from the Gordon and Betty Moore Foundation, announced last week, will allow iNaturalist—whose website is one of the largest generators of crowd-sourced species-occurrence data—to add users, technology, and observations to inform conservation. iNaturalist hopes to grow in nature-rich parts of the world, such as Asia and South America, which have fewer users uploading data. Since iNaturalist’s founding in 2008, the ...
Source: Science of Aging Knowledge Environment - September 21, 2023 Category: Geriatrics Source Type: research

News at a glance: Diphtheria treatment shortage, prisoner release, and iNaturalist ’s growth
CONSERVATION Popular biodiversity app to expand The nonprofit that runs iNaturalist, a popular app and website for identifying species, has received a $10 million grant to expand. The funding from the Gordon and Betty Moore Foundation, announced last week, will allow iNaturalist—whose website is one of the largest generators of crowd-sourced species-occurrence data—to add users, technology, and observations to inform conservation. iNaturalist hopes to grow in nature-rich parts of the world, such as Asia and South America, which have fewer users uploading data. Since iNaturalist’s founding in 2008, the ...
Source: ScienceNOW - September 21, 2023 Category: Science Source Type: news

How Wastewater Testing Can Help Tackle America ’ s Opioid Crisis
Among the many lasting legacies of COVID-19 may be a newfound appreciation for the value of what we flush down the toilet and wash down the drain. Wastewater can be a rich source of information about infectious diseases, like COVID-19, as well as flu, respiratory syncytial virus (RSV), mpox and polio, since pathogens like viruses are shed in feces, urine and saliva, all of which is drained into sewage treatment plants. Sampling that water is a good way to screen for certain viruses, and, as more people bypass the medical system and labs in favor of testing themselves at home for things like COVID-19, health agencies lik...
Source: TIME: Health - September 21, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Mucormycosis: update on clinical presentation, diagnosis, and treatment
Curr Opin Infect Dis. 2023 Sep 22. doi: 10.1097/QCO.0000000000000976. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Mucormycosis (MCR) is a common opportunistic mold infection, and Mucorales were recently designated by WHO as priority pathogens. The interest in this infection has risen significantly since the major outbreak of MCR in the context of the COVID-19 pandemic, particularly in India. Herein, we summarize recently (last 24 months) published information regarding clinical aspects of MCR.RECENT FINDINGS: The disease remains protean in its clinical presentation, difficult to diagnose, and challenging to treat. In ...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Natalie J M Dailey Garnes Dimitrios P Kontoyiannis Source Type: research

Cross-jurisdictional pandemic management: providers speaking on the experience of Nunavut Inuit accessing services in Manitoba during the COVID-19 pandemic
Int J Circumpolar Health. 2023 Dec;82(1):2259122. doi: 10.1080/22423982.2023.2259122. Epub 2023 Sep 20.ABSTRACTAcross Canada, the COVID-19 pandemic placed considerable stress on territorial and provincial healthcare systems. For Nunavut, the need to continue to provide access to critical care to its citizens meant that medical travel to provincial points of care (Edmonton, Winnipeg and Ottawa) had to continue through the pandemic. This complexity created challenges related to the need to keep Nunavut residents safe while accessing care, and to manage the risk of outbreaks in Nunavut resultant from patients returning home. ...
Source: International Journal of Circumpolar Health - September 21, 2023 Category: International Medicine & Public Health Authors: Jos ée G Lavoie Wayne Clark Leah McDonnell Nathan Nickel Rachel Dutton Janet Kanayok Melinda Fowler-Woods Jac Anawak Nuqaalaq Brown Grace Voisey Clark Tagaak Evaluardjuk-Palmer Sabrina T Wong Julianne Sanguins Adriana Mudryj Nastania Mullins Marti Ford J Source Type: research

Countering Mpox Vaccination Disparities in Los Angeles County, California, May-December 2022
Am J Public Health. 2023 Sep 21:e1-e5. doi: 10.2105/AJPH.2023.307409. Online ahead of print.ABSTRACTProviding equitable access to vaccines for individuals at risk for mpox was critical for containing the 2022 mpox outbreak in Los Angeles County, California. Eligible non-Hispanic Black/African American and Latinx individuals had lower vaccine uptake than did non-Hispanic White individuals, despite having higher mpox case rates. Strategies to address disparities in vaccine uptake included using familiar messaging technology to reach individuals at risk for mpox, using partnerships with community-based organizations to raise ...
Source: Am J Public Health - September 21, 2023 Category: International Medicine & Public Health Authors: Auguste Brihn Nava Yeganeh Sonali Kulkarni Olivia Moir Saloniki Madrid Mario Perez Rita Singhal Andrea A Kim Source Type: research

pH-dependent conformational change within the Lassa virus transmembrane domain elicits efficient membrane fusion
Biochim Biophys Acta Biomembr. 2023 Sep 19:184233. doi: 10.1016/j.bbamem.2023.184233. Online ahead of print.ABSTRACTLassa virus (LASV) is the most prevalent member of the arenavirus family and the causative agent of Lassa fever, a viral hemorrhagic fever. Although there are annual outbreaks in West Africa, and recently isolated cases worldwide, there are no current therapeutics or vaccines, which poses LASV as a significant global public health threat. One of the key steps in LASV infection is the delivery of its genetic material by fusing its viral membrane with the host cell membrane. This process is facilitated by signi...
Source: Biochimica et Biophysica Acta - September 21, 2023 Category: Biochemistry Authors: Patrick M Keating Nicholas P Schifano Xinrui Wei Matthew Y Kong Jinwoo Lee Source Type: research

Task Force for a rapid response to an outbreak of severe acute hepatitis of unknown aetiology in children in Portugal in 2022
Euro Surveill. 2023 Sep;28(38). doi: 10.2807/1560-7917.ES.2023.28.38.2300171.ABSTRACTOn 5 April 2022, the United Kingdom reported an increase of cases of severe acute hepatitis of unknown aetiology in children, several needing hospitalisation and some required liver transplant or died. Thereafter, 35 countries reported probable cases, almost half of them in Europe. Facing the alert, on 28 April, Portugal created a multidisciplinary Task Force (TF) for rapid detection of probable cases and response. The experts of the TF came from various disciplines: clinicians, laboratory experts, epidemiologists, public health experts an...
Source: Euro Surveill - September 21, 2023 Category: Infectious Diseases Authors: Berta Grau-Pujol Jo ão Vieira Martins Isabel Goncalves Fernanda Rodrigues Rita de Sousa Dina Oliveira Joana Bettencourt Diana Mendes In ês Mateus de Cunha Sara Pocinho Ana Firme Benvinda Estela Dos Santos Andr é Peralta Santos Maria Jo ão Albuquerque Source Type: research

Countering Mpox Vaccination Disparities in Los Angeles County, California, May-December 2022
Am J Public Health. 2023 Sep 21:e1-e5. doi: 10.2105/AJPH.2023.307409. Online ahead of print.ABSTRACTProviding equitable access to vaccines for individuals at risk for mpox was critical for containing the 2022 mpox outbreak in Los Angeles County, California. Eligible non-Hispanic Black/African American and Latinx individuals had lower vaccine uptake than did non-Hispanic White individuals, despite having higher mpox case rates. Strategies to address disparities in vaccine uptake included using familiar messaging technology to reach individuals at risk for mpox, using partnerships with community-based organizations to raise ...
Source: American Journal of Public Health - September 21, 2023 Category: International Medicine & Public Health Authors: Auguste Brihn Nava Yeganeh Sonali Kulkarni Olivia Moir Saloniki Madrid Mario Perez Rita Singhal Andrea A Kim Source Type: research

Prevalence of Type III Secretion System (T3SS) and Biofilm Development in Genetically Heterogeneous Clinical Isolates of Pseudomonas aeruginosa from Nigeria
This study examined 430 clinical isolates from our previous work, comprising 181 MDR (multidrug-resistant) and 249 non-MDR isolates. Biofilm production and type III secretion toxins were determined using colorimetric microtiter plate assay and polymerase chain reaction, respectively. Carbapenem-resistant isolates were typed using REP-PCR and BOX-PCR. Biofilm production was detected in 386/430 (89.8%) of the isolates. Out of 386 biofilm producers, 167 (43.3%) were multidrug-resistant isolates. PCR identified four T3SS virulence types among 430 isolates, including 78 (18.1%) exoU+/exoS- isolates, 343 (79.8%) exoU-/exoS + iso...
Source: Current Microbiology - September 21, 2023 Category: Microbiology Authors: Oluwatoyin B Olaniran Ahmed Donia Olufemi E Adeleke Habib Bokhari Source Type: research