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Infectious Disease: Gastroenteritis
Vaccination: Rotavirus Vaccine

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Total 210 results found since Jan 2013.

National rotavirus vaccination programme implementation and gastroenteritis presentations: the paediatric emergency medicine perspective
ConclusionA reduction in PED presentations with AGE is demonstrated post-rotavirus vaccine introduction into the Irish National Immunisation Schedule. No significant change in paediatric hospital admissions was demonstrated.
Source: Irish Journal of Medical Science - June 12, 2019 Category: General Medicine Source Type: research

Molecular epidemiology of human bocavirus in children with acute gastroenteritis from North Region of Brazil.
CONCLUSION: Our findings provide evidence for the circulation of most HBoV genotypes (except HBoV-4) in the North Region of Brazil at a considerable rate and further investigations are necessary to improve our knowledge in the context of HBoV infections and their role in gastrointestinal diseases. PMID: 31215861 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - June 18, 2019 Category: Microbiology Authors: Soares LS, Lima ABF, Pantoja KC, Lobo PS, Cruz JF, Guerra SFS, Bezerra DAM, Bandeira RS, Mascarenhas JDP Tags: J Med Microbiol Source Type: research

Evaluation of non-specific effects of human rotavirus vaccination in medical risk infants
CONCLUSION: The results suggest no, or minimal non-specific effects from rotavirus vaccination on acute hospitalization, acute respiratory illness or eczema in medical risk infants.TRIAL REGISTRATION: as NTR5361 in the Dutch trial registry, www.trialregister.nl.PMID:34507856 | DOI:10.1016/j.vaccine.2021.08.067
Source: Vaccine - September 11, 2021 Category: Allergy & Immunology Authors: Josephine A P van Dongen Elsbeth D M Rouers Marc J M Bonten Patricia C J Bruijning-Verhagen RIVAR study team Source Type: research

Evidence of Herd Immunity and Sustained Impact of Rotavirus Vaccination on the Reduction of Rotavirus-Related Medical Encounters Among Infants from 2006 through 2011 in the United States
Conclusions: Analysis of a national medical claims database indicates a sustained and substantial decrease in the seasonal RV medical claims pattern after the introduction of RVV. This analysis also reveals evidence of herd immunity, although unvaccinated infants continue to be at risk and contribute to smaller seasonal peaks in RV disease activity.
Source: The Pediatric Infectious Disease Journal - May 16, 2015 Category: Infectious Diseases Tags: Vaccine Reports Source Type: research

Changes in the numbers of patients with acute gastroenteritis after voluntary introduction of the rotavirus vaccine in a Japanese children ’s primary emergency medical center
ConclusionsThe estimated rotavirus vaccine coverage in our area increased from 1% in 2011 to 49% in 2014; this coverage may have resulted in a reduction in AGE patients, both directly and indirectly, in our Japanese children ’s primary emergency medical center.
Source: Environmental Health and Preventive Medicine - March 31, 2017 Category: Environmental Health Source Type: research

Rotavirus Vaccine Safety and Effectiveness in Infants With High-Risk Medical Conditions
CONCLUSIONSIn contrast to previous findings among healthy term infants, in routine use, HRV offered limited protection to vulnerable medical risk infants. HRV is generally well tolerated in this group in single administration, but when coadministered with routine vaccines, it is associated with higher risk of (mostly gastrointestinal) AE. Our study highlights the importance of studying vaccine performance in subgroups of medically vulnerable infants.
Source: PEDIATRICS - December 1, 2021 Category: Pediatrics Source Type: research

Epidemiology and medical cost of hospitalization due to rotavirus gastroenteritis among children under 5 years of age in the central-east of Tunisia.
This study aimed to describe the epidemiological profile of rotavirus disease in central-east Tunisia and to estimate its hospital cost. In the first stage - the prospective collection of epidemiological data - we enrolled all patients < 5 years old who were hospitalized for acute diarrhoea at 5 university paediatric departments in central-east Tunisia during the period 2009-2011. Rotavirus was responsible for 65 (23.3%) of the 279 cases enrolled. In the second stage, cost data were collected retrospectively using an activity-based costing method from the medical records of the children who were positively diagnosed wit...
Source: Eastern Mediterranean Health Journal - November 20, 2015 Category: Middle East Health Tags: East Mediterr Health J Source Type: research

Detection of Rotavirus Genotypes in Korea 5 Years after the Introduction of Rotavirus Vaccines.
This study documented RV genotypes in a Korean population of children with AGE 5 yr after the introduction of RVV and assessed potential genotype differences based on vaccination status or vaccine type. Children less than 5-yr-old diagnosed with AGE between October 2012 and September 2013 admitted to 9 medical institutions from 8 provinces in Korea were prospectively enrolled. Stool samples were tested for RV by enzyme immunoassay and genotyped by multiplex reverse-transcription polymerase chain reaction. In 346 patients, 114 (32.9%) were RV-positive. Among them, 87 (76.3%) patients were infected with RV alone. Eighty-six ...
Source: Journal of Korean Medical Science - October 2, 2015 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Prevalence and characterization of rotaviruses in children hospitalized for diarrheal disease in a tertiary care hospital, Pune
Conclusion: Genotypes found in circulation are not present in the currently used vaccine. Thus, an emergence of newer genotypes over a period calls for the continued surveillance and genomic characterisation of rotaviruses to improve the vaccine efficacy.
Source: Indian Journal of Medical Microbiology - March 15, 2017 Category: Microbiology Authors: Sae Satish Pol Ashwini Kacharu Dedwal Sujata Sudhir Ranshing Shobha Dattatray Chitambar Sushma Narayan Pednekar Renu Satish Bharadwaj Source Type: research

Long-term impact of suboptimal rotavirus vaccines on acute gastroenteritis in hospitalized children in Northern Taiwan
Conclusion In Taiwan, under a suboptimal rotavirus vaccination policy, there was a marked decrease in the rate of rotavirus AGE of hospitalized young children. Significantly increased norovirus infection has replaced rotavirus as the leading cause. Expansion of rotavirus vaccine coverage, development of a norovirus prevention strategy, and sustained bacterial infection control are important for AGE containment in children in Taiwan.
Source: Journal of the Formosan Medical Association - October 12, 2017 Category: General Medicine Source Type: research

Full genomic analysis of G1P8 rotavirus strains recovered from rotavirus vaccinated and non ‐vaccinated children hospitalized for acute gastroenteritis in Pune, western India
Journal of Medical Virology,Volume 90, Issue 4, Page 772-778, April 2018.
Source: Journal of Medical Virology - December 15, 2017 Category: Virology Source Type: research

Molecular epidemiology of rotavirus gastroenteritis in Japan during 2014 ‐2015: Characterization of re‐emerging G2P4 after rotavirus vaccine introduction
Journal of Medical Virology, EarlyView.
Source: Journal of Medical Virology - March 13, 2018 Category: Virology Source Type: research

Long-term impact of suboptimal rotavirus vaccines on acute gastroenteritis in hospitalized children in Northern Taiwan
ConclusionIn Taiwan, under a suboptimal rotavirus vaccination policy, there was a marked decrease in the rate of rotavirus AGE of hospitalized young children. Significantly increased norovirus infection has replaced rotavirus as the leading cause. Expansion of rotavirus vaccine coverage, development of a norovirus prevention strategy, and sustained bacterial infection control are important for AGE containment in children in Taiwan.
Source: Journal of the Formosan Medical Association - July 20, 2018 Category: General Medicine Source Type: research

Acute Gastroenteritis in Children of the World: What Needs to Be Done?
The incidence of gastroenteritis has greatly reduced due to improved hygiene conditions in developing countries and the use of rotavirus vaccine. Still thousands of children, however, die from gastroenteritis, most of them in poor countries. Yet gastroenteritis management is simple, inexpensive, and effective and is largely the same all over the world. Universal guidelines for gastroenteritis guide the management and include simple interventions put forward early in the course of the disease. Treatment includes rehydration, continuing oral feeding, and anti-infective drugs in selected clinical conditions related to the sym...
Source: Journal of Pediatric Gastroenterology and Nutrition - April 27, 2020 Category: Gastroenterology Tags: Society Papers Source Type: research