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Total 61 results found since Jan 2013.

New bird flu strain requires vigilance researchers warn
Conclusion This is important research tracking the origins of the new H7N9 bird flu virus, which gives some clues about how it might behave in the future. Scientists are particularly concerned that a future mutation could mean it is transmitted between humans, which increases the risk of a pandemic (an epidemic of infection across countries or continents). For travellers to China and other countries affected by bird flu, it's important to observe the following precautions: avoid visiting live animal markets and poultry farms avoid contact with surfaces that are contaminated with animal faeces don't eat or handle u...
Source: NHS News Feed - May 2, 2013 Category: Consumer Health News Tags: Genetics/stem cells Medical practice Source Type: news

HIV 's efficiency makes it a formidable foe
Although antiretroviral drug therapy suppresses the virus, it cannot get rid of it or end the epidemicAntiretroviral drugs have been an astounding success story, reprieving people with HIV from the brink of death and allowing them to live a full and healthy life. But although the roll-out across the world has saved lives and removed the distressing pictures of wasted Aids victims from our TV screens, experts know the drugs will not end the epidemic. The hunt is on for a cure, but it is proving tough.Antiretroviral drug therapy suppresses the virus to such low levels that people with HIV are no longer infectious, but it can...
Source: Guardian Unlimited Science - March 6, 2014 Category: Science Authors: Sarah Boseley Tags: The Guardian United States World news Health Medical research UK news Aids and HIV Science Society Source Type: news

Can you smell the perfect partner?
Is Tim Dowling married to the right woman? A new book suggests that we unconsciously select the perfect partner by sniffing out their 'compatibility genes'. He talks to the author about MHC genetics and alleles – then nervously asks his wife to take a DNA testAt first, I'm not even sure how best to frame the question in order to secure my wife's participation."Would you mind taking a quick DNA test," I say, "to determine our genetic compatibility?""Am I going to be told I have a fatal disease?" she asks."No," I say. "It's just to find out whether or not we were meant to be together.""Oh," she says. "Fine. Whatever."On th...
Source: Guardian Unlimited Science - September 9, 2013 Category: Science Authors: Tim Dowling Tags: The Guardian Genetics Biology Features Life and style Relationships Science Source Type: news

Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic
Conclusions In conclusion, since there are now numerous animal and epidemiological studies indicating that environmental pollutants could contribute to the global obesity epidemic, there is an urgent need to reduce the burden of environmental contaminants so that obesity does not become the normal outlook in the future. The workshop attendees concluded that public health efforts should focus on the importance of early obesity prevention by means of reducing chemical exposures, rather than only treating the established disease. Just as a bad start can last a lifetime and beyond, a good start can last a lifetime as well. Re...
Source: EHP Research - May 2, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication May 2016 Source Type: research

Impact of Influenza Infection Among Adult and Pediatric Populations With Hematologic Malignancy and hematopoietic Stem Cell Transplant: A Systematic Review and Meta-Analysis
This study systematically reviewed and summarized the outcomes of influenza infection as to in-hospital influenza-related mortality, development of lower respiratory tract infection and acute respiratory distress syndrome, need for hospitalization, intensive care unit admission, and mechanical ventilation.METHODS: We conducted a systematic search of literature using the PubMed and EMBASE databases for articles published from January 1989 through January 19, 2020, reporting laboratory-confirmed influenza in patients of any age with hematologic malignancies and HSCT. Time from transplantation was not included in the search c...
Source: Clinical Therapeutics - April 4, 2021 Category: Drugs & Pharmacology Authors: Eleftheria Atalla Markos Kalligeros Evangelia K Mylona Maria Tsikala-Vafea Fadi Shehadeh Joanna Georgakas Eleftherios Mylonakis Source Type: research

Shortage Of Organs For Transplantation -- Is More Research on Human-Animal Chimeras the Right Approach?
This piece was originally published on Bionews and co-authored with Giulia Cavaliere. You can read the original piece here. It is time to discuss, once again, the lifting of a moratorium on research. We are not talking about the CRISPR genome-editing moratorium, but about the 20 August announcement by the US National Institutes of Health (NIH) to lift the moratorium on research involving chimeric human/non-human embryos. The use of federal funds for this kind of research had been previously banned by the NIH in September 2015. Although it does not state it explicitly, the NIH announcement seems to have been triggered by ...
Source: Science - The Huffington Post - September 15, 2016 Category: Science Source Type: news

OBK-17-0008 Does Zika Virus Cause Microcephaly – Applying the Bradford Hill Viewpoints
This study included more recent evidence compared to the previous one. The Bradford-Hill Viewpoints are used in public health to determine causation of diseases.11 Systematic application of the viewpoints can assist with analysing a possible causal relationship. Additional studies to assess the risk of microcephaly in affected pregnant mothers are ongoing.12 In this study we applied the Bradford-Hill viewpoints to investigate the association between Zika virus and Microcephaly. Method Using the Bradford Hills nine viewpoints we analysed data from a 2013 outbreak in French Polynesia and the 2015 Brazilian outbreak to esta...
Source: PLOS Currents Outbreaks - February 22, 2017 Category: Epidemiology Authors: asma Source Type: research

Does Zika Virus Cause Microcephaly – Applying the Bradford Hill Viewpoints
This study included more recent evidence compared to the previous one. The Bradford-Hill Viewpoints are used in public health to determine causation of diseases.11 Systematic application of the viewpoints can assist with analysing a possible causal relationship. Additional studies to assess the risk of microcephaly in affected pregnant mothers are ongoing.12 In this study we applied the Bradford-Hill viewpoints to investigate the association between Zika virus and Microcephaly. Method Using the Bradford Hills nine viewpoints we analysed data from a 2013 outbreak in French Polynesia and the 2015 Brazilian outbreak to esta...
Source: PLOS Currents Outbreaks - February 22, 2017 Category: Epidemiology Authors: asma Source Type: research

The Role of Fat Grafting in Alleviating Neuropathic Pain: A Critical Review of the Literature
Conclusions: Fat grafting is an emerging therapy for chronic neuropathic pain of various etiologies. Although promising results have been reported, sample size and level of evidence of current studies are low. The encouraging results, however, are worthy of further clinical and scientific study. The minimally invasive nature of fat grafting and favorable risk profile make this an attractive therapy for neuropathic pain.
Source: Plastic and Reconstructive Surgery – Global Open - May 1, 2019 Category: Cosmetic Surgery Tags: Experimental Source Type: research

NIDCR's Spring 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Spring 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   Grantee News   NIDCR News NIDCR & NIH Stand Against Structural Racism NIDCR Director Rena D’Souza, DDS, MS, PhD, said in a statement that there is no place for structural racism in biomedical research, echoing remarks from NIH Director Francis Collins, MD, PhD, in his announcement of a new NIH initiative—called UNIT...
Source: NIDCR Science News - April 7, 2021 Category: Dentistry Source Type: news

Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development
Conclusions HAND2 methylation is a common and crucial molecular alteration in endometrial cancer that could potentially be employed as a biomarker for early detection of endometrial cancer and as a predictor of treatment response. The true clinical utility of HAND2 DNA methylation, however, requires further validation in prospective studies.Please see later in the article for the Editors' Summary
Source: PLoS Medicine - November 12, 2013 Category: Internal Medicine Authors: Allison Jones et al. Source Type: research

Ptr/CTL0175 Is Required for the Efficient Recovery of Chlamydia trachomatis From Stress Induced by Gamma-Interferon
In this study, we carried out a screen to identify C. trachomatis genes important for recovery from IFNγ- and/or penicillin-induced stress. We found that ptr, encoding a poorly characterized secreted protease, is required for rapid recovery from IFNγ- but not penicillin-induced stress. Materials and Methods Cell Culture, Infection and C. trachomatis Strains HeLa (CCL-2, ATCC) and Vero cells (CCL-81, ATCC) were cultured in high glucose Dulbecco’s modified Eagle’s medium (Gibco) supplemented with 10% FBS (Natocor) without antibiotics in 5% CO2 at 37°C in a humidified atmosphere. Cells we...
Source: Frontiers in Microbiology - April 9, 2019 Category: Microbiology Source Type: research

Stem cell injections for axial back pain: a systematic review of associated risks and complications with a case illustration of diffuse hyperplastic gliosis resulting in cauda equina syndrome.
CONCLUSIONS: There are still insufficient data to support stem cell injections for back pain. Additional RCTs with long-term follow-up are necessary before statements can be made regarding the efficacy and safety. PMID: 31491761 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery.Spine - September 5, 2019 Category: Neurosurgery Authors: Aoun SG, Peinado Reyes V, El Ahmadieh TY, Davies M, Patel AR, Ban VS, Plitt A, El Tecle NE, Moreno JR, Raisanen J, Bagley CA Tags: J Neurosurg Spine Source Type: research

A Debate On The Pros And Cons Of Aging And Death
At age 74, I have already experienced many of the indignities of aging and before very long will also confront the inevitability of death. Although neither prospect is particularly pleasant, I strongly believe in the normality and necessity of both. Claims that science will soon prevent aging and dramatically prolong life strike me as irresponsible hype and false hope. I am all for efforts to expand our healthspan, but see little value in prolonging our lifespan, and little possibility that we will soon discover a fountain of youth.  My grandson, home from college for Christmas break, disagrees with what he regards as ...
Source: Science - The Huffington Post - December 24, 2016 Category: Science Source Type: news