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Total 388 results found since Jan 2013.

Immunological and molecular study in children with combined immunodeficiency
Conclusions. To evaluate SCID patients completely; mutation gene analysis is highly required and recommended.PMID:36786340 | DOI:10.23822/EurAnnACI.1764-1489.286
Source: European Annals of Allergy and Clinical Immunology - February 14, 2023 Category: Allergy & Immunology Authors: S Kholoussi A Ramadan N Kholoussi E A Ashaat A G Fayez H A Raouf I Helwa N N Esmaiel R Ghorab A M Abo-Shanab Source Type: research

Marginal Zone
Cartootorial: In 1930, LA Wadell reported that Pharaoh Menes of Egypt died in 2641 BCE of insect sting anaphylaxis, a fact that has oft been repeated in the Allergy literature.1,2 While intriguing, this isn't supported by other historians.1 –3 Wadell's claim was based on his own interpretation of hieroglyphs from a purported burial site for Menes, which he said depicted wasps.1,2 In contrast, Manetho, a 3rd century BCE priest and Egyptian historian, wrote extensively about Menes, stating he “was carried off by a hippopotamus and pe rished.”2,3 Modern historians have noted similarities in hieroglyphs used to depict wa...
Source: Annals of Allergy, Asthma and Immunology - August 1, 2023 Category: Allergy & Immunology Authors: Erin L. Reigh Tags: Marginal Zone Source Type: research

The Gut-Immune-Brain Axis in Autism Spectrum Disorders; A Focus on Amino Acids
Conclusion In Table 1, an overview is presented of the complex roles of AAs described in this review regarding the microbiome-gut-immune-brain axis in ASD. Besides behavioral deficits, people with ASD are characterized by systemic inflammation, gastrointestinal immune-related disturbances and changes in the gut microbiota composition. Moreover, differences in levels of specific AAs in various body compartments, including the intestinal tract, blood, urine and brain have been reported in patients with ASD, as well as in rodent models for ASD. This review described that specific AAs can modulate the intestinal epithelial im...
Source: Frontiers in Endocrinology - April 15, 2019 Category: Endocrinology Source Type: research

Food sensitization in preschool Egyptian children with recurrent wheezing.
CONCLUSIONS: Food sensitization is common in preschool Egyptian children with recurrent wheezing. IMPACT: Food sensitization is common in children with prevalence up to 10%, and in atopic children up to 30%.Sensitization to fish was the most common type of sensitization observed among preschool children with recurrent wheezing, followed by milk, eggs, and wheat, respectively.SPT aided by history is a good screening tool to determine whether patients need to avoid some foods that can cause allergy in order to help in controlling their symptoms. PMID: 32485730 [PubMed - as supplied by publisher]
Source: Pediatric Research - June 1, 2020 Category: Pediatrics Authors: Abdallah AM, Osman NS, Mohammad HA, Metwalley KA, Embaby M, ElMelegy TT Tags: Pediatr Res Source Type: research

Pollen Sensitization in Association with Allergic Rhinitis in preschool asthmatic Children
ConclusionIt is concluded from our results that sensitization to timothy grass pollen (TGP) is common in allergic rhinitis. The findings are limited by the sample size and consecutive manner of sampling. Wider scale studies are needed to accurately evaluate the frequency of timothy grass pollen (TGP) sensitization in our country.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

The hidden impact of different Blastocystis genotypes on C-3 and IgE serum levels: a matter of debate in asthmatic Egyptian children
In conclusion,B. hominis possess a hidden allergy triggering impact that can be obscured by simultaneous high (total and specific) IgE levels towards specific common intestinal allergens. Blastocystosis induces allergy by increasing C-3 serum levels in a genotype-dependent manner being higher in genotype-3. Virulence of genotype-3 seems to stand beyond increased parasite intensity and wide absorption of intestinal allergens that indirectly elevate IgE serum levels.
Source: Journal of Parasitic Diseases - March 29, 2019 Category: Parasitology Source Type: research

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry
Discussion Tibroviruses are highly undercharacterized rhabdoviruses with unknown pathogenic potential. All isolated tibroviruses (BAV, BHV, CPV, SWBV, and TIBV) have only been found in biting midge vectors or in various, apparently healthy non-human mammals (Cybinski et al., 1980; Standfast et al., 1984; Cybinski and Gard, 1986; Gibbs et al., 1989). The discovery of BASV, EKV-1, and EKV-2 genomes in human sera (Grard et al., 2012; Stremlau et al., 2015) suggests that at least some tibroviruses could infect humans. Because BASV was discovered in the serum of a severely ill individual, tibroviruses should be considered pote...
Source: Frontiers in Microbiology - April 25, 2019 Category: Microbiology Source Type: research

Combining Understanding of Immunological Mechanisms and Genetic Variants Toward Development of Personalized Medicine for Psoriasis Patients
Conclusion Although GWAS contributed insight into the utility of the genotype biomarker to treatment selection, adequately powered prospective studies will be required before clinical application of pharmacogenomics can become a reality. Genotype and phenotype assessment should be facilitated by the availability of detailed molecular analyses and data integration. Careful assessment of prospective GWAS data is essential to integrate findings into the clinical decision-making process, and thereby optimizing the treatment of patients with psoriasis in the future. Author Contributions BY, NG, and WY performed the project. ...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

The prevalence of keratoconus in children with allergic eye disease in an Egyptian population.
CONCLUSION: The overall prevalence of KC was 34%. Risk factors for the development of KC in patients with ocular allergy were age, duration of symptoms specially eye rubbing, systemic atopy and VKC. Tomographic diagnosis of KC can be present in absence of clinical signs. PMID: 32659124 [PubMed - as supplied by publisher]
Source: European Journal of Ophthalmology - July 12, 2020 Category: Opthalmology Authors: Ahmed AS, El-Agha MH, Khaled MO, Shousha SM Tags: Eur J Ophthalmol Source Type: research

Effects of body weight and posture on pulmonary functions in asthmatic children
Conclusion: There was no effect of weight on standing spirometric data. Weight showed significant negative correlation with asthma control level. We concluded that in overweight/obese asthmatic childr en, spirometric position might affect the results.Keywords: Body weight; posture; asthmatic children.
Source: African Health Sciences - December 16, 2020 Category: African Health Authors: Ghobrial Emad Emil, El Baz Mohamed Saad, Abdel Fattah Mohammed, Haroun Manar Mohamed Source Type: research

Immunoproteomic identification of allergenic proteins in pecan (Carya illinoinensis) pollen
This study has identified 17 IgE binding proteins from pecan pollen including proteins widely recognized as allergens and panallergens. These findings will contribute to develop specific diagnosis and treatment of pecan pollen allergy. SIGNIFICANCE: Pecan is a tree highly valued for its fruits that have a great commercial value. To date three pecan seed storage proteins have been officially recognized by the WHO/IUIS allergen nomenclature subcommittee as food allergens (Car i 1, Car i 2 and Car i 4). Pecan tree pollen is highly allergenic and a clinically relevant cause of allergies in North America (USA and Mexico) and re...
Source: Journal of Proteomics - August 15, 2021 Category: Biochemistry Authors: Martha Beatriz Morales-Amparano Alejandra Valenzuela-Corral Gabriela Ramos-Clamont Montfort Luz V ázquez-Moreno Abraham Escobedo-Moratilla Guillermo Pastor-Palacios Cesar é Ovando-Vázquez Luis M Teran Jos é Ángel Huerta-Ocampo Source Type: research