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Total 2124 results found since Jan 2013.

Delabeling Penicillin Allergy in Pregnancy Using Innovation and Patient Education
Ten percent of patients report a penicillin (PCN) allergy although
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Rosemary Moak, Caroline Nassab, Emily Campbell, Maria Streck, Gweneth Lazenby, Corinne Corrigan, Kelli Williams Source Type: research

Improving Access To Penicillin Allergy Testing Among Pregnant Patients In An Obstetrics Clinic
Beta-lactam antibiotics are first-line for most infections during pregnancy and delivery. We assessed outcomes of proactive screening and referral from an obstetrics (OB) clinic for penicillin allergy evaluation.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Lauren Franzblau, Yetunde Awosemusi, James Sanders, James Cutrell, David Khan Source Type: research

Early exposure to peanuts 'cuts allergy risk in children'
Conclusion This was a follow-up study of a well-designed randomised controlled trial. The original study found the early introduction of regular small amounts of peanut protein to infants at high risk of having peanut allergy reduced the proportion that developed a peanut allergy by the age of five, compared with avoiding peanuts completely. The latest study found that even if the children who had been exposed to peanuts then avoided them for 12 months, this did not significantly increase their likelihood of developing a peanut allergy. Strengths of the study include the use of objective tests to determine how well th...
Source: NHS News Feed - March 7, 2016 Category: Consumer Health News Tags: Food/diet Pregnancy/child Source Type: news

Pregnancy and peanuts: the end of the avoidance theory
Pregnant women often avoid (or at least limit) some of the foods they’d normally like to eat because of the chance those menu items could hurt the health of their baby. In many cases it’s the right thing to do, but women who fear that eating peanuts during pregnancy could cause their child to one day develop a peanut allergy needn’t worry, according to a Boston Children’s Hospital study. “Our study showed that increased peanut consumption by pregnant mothers who weren’t themselves nut-allergic was associated with lower risk of peanut allergy in their children,” says senior author Michael Y...
Source: Thrive, Children's Hospital Boston - December 24, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Food allergies Allergy and Immunology Division peanut allergies peanut allergy pregnancy Source Type: news

Peanut allergy therapy shows promise
Conclusion This well-conducted study has shown that children with peanut allergy can be treated successfully with immunotherapy. The main aim of these treatments is to avoid severe allergic reactions if the child accidentally eats peanuts. An important issue not addressed by the study is how long the effects of the immunotherapy might last, and whether the positive effects might lead to a false sense of security. Studies are needed to determine how long and how frequently maintenance immunotherapy doses need to continue to be given to maintain peanut tolerance in these children. Studies will also be needed to determine ...
Source: NHS News Feed - January 30, 2014 Category: Consumer Health News Tags: Medical practice Pregnancy/child Source Type: news

Survey of Obstetric Providers to Assess the Knowledge and Management of a Reported Penicillin Allergy in Pregnant Women
Conclusions Knowledge gaps related to penicillin allergy exist among obstetric providers. Educational initiatives may improve provider knowledge, help in the identification of patients requiring penicillin allergy evaluation, and reduce referral barriers. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: American Journal of Perinatology - September 12, 2022 Category: Perinatology & Neonatology Authors: Cate, Jennifer J. M. Burn, Martina Kwah, Jason Liao, Jane Illuzzi, Jessica Reddy, Uma Son, Moeun Tags: SMFM Fellows Research Series Source Type: research

Low-grade disease activity in early life precedes childhood asthma and allergy.
In conclusion, the series of papers presented in this thesis (I-VII) evidence the presence of a pre-symptomatic disease process measurable in several body compartments, which supports the notion of low-grade disease activity in early life as a generic trait among neonates developing asthma and allergy. This hypothesis piggybacking on single biomarker assessments could be enforced and refined by applying novel global omics approaches. In particular, metabolomic analyses of serum, urine, and airway lining fluid from neonates as well as neonatal VOC profiling of exhaled breath may facilitate a broader understanding of the ear...
Source: Danish Medical Journal - August 2, 2016 Category: Journals (General) Tags: Dan Med J Source Type: research

Outpatient Penicillin Allergy Testing in Pregnant Women Who Report an Allergy.
CONCLUSION: Outpatient penicillin allergy testing is acceptable and feasible in pregnancy. PMID: 33278285 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - December 3, 2020 Category: OBGYN Authors: Desravines N, Waldron J, Venkatesh KK, Kwan M, Boggess KA Tags: Obstet Gynecol Source Type: research

Pregnant Patients with a Documented History of Penicillin Allergy and Associated Maternal and Neonatal Outcomes at a Tertiary Care Center
Conclusion Pregnant patients who are labeled as having a penicillin allergy are more likely to have postpartum endometritis, and neonates born to mothers who are labeled as having a penicillin allergy are more likely to have a postnatal hospital stay lasting more than 72 hours. There were no other significant differences seen in pregnant patients and their newborns whether they were labeled as having a penicillin allergy history or not. However, pregnant individuals with a penicillin allergy documented in their medical record were significantly more likely to receive alternative non-β lactam antibiotics, and may have ...
Source: American Journal of Perinatology - June 19, 2023 Category: Perinatology & Neonatology Authors: Azmy, Veronica Lundsberg, Lisbet S. Culhane, Jennifer Kwah, Jason Partridge, Caitlin Son, Moeun Tags: Original Article Source Type: research

Time Has Come for Routine Penicillin Allergy Testing in Obstetrics
Conclusion Most women who report a penicillin allergy during pregnancy would be candidates for penicillin allergy testing. With the high rate of antibiotic interventions in pregnant women who report a penicillin allergy, consideration should be given for penicillin allergy assessment. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: American Journal of Perinatology Reports - February 3, 2020 Category: Perinatology & Neonatology Authors: Cook, Elizabeth Ramirez, Mildred Turrentine, Mark Tags: Original Article Source Type: research

Relationship between maternal –infant gut microbiota and infant food allergy
The gut microbiota plays a crucial role in food allergies. We sought to identify characteristics of the maternal gut microbiota in the third trimester and the infant gut microbiota in early life and the association of these microbiotas with infant food allergy. A total of 68 healthy pregnant women and their full-term newborns were selected from a cohort of 202 mother–infant pairs; among them, 24 infants had been diagnosed with food allergy within 1 year of age, whereas 44 infants were healthy without allergic symptoms. We collected 65 maternal fecal samples before delivery and 253 infant fecal samples at five time points...
Source: Frontiers in Microbiology - November 7, 2022 Category: Microbiology Source Type: research

Screening for the risk of allergy and prevention in French maternity units: A survey.
Abstract Allergy has been on the rise for half a century and concerns nearly 30% of children; it has now become a real public health problem. The guidelines on prevention of allergy set up by the French Society of Paediatrics (SFP) and the European Society of Paediatric Allergology and Clinical Immunology (ESPACI) are based on screening children at risk through a systematic search of the family history and recommend, for children at risk, exclusive breastfeeding whenever possible or otherwise utilization of hypoallergenic infant formula, which has demonstrated efficacy. The AllerNaiss practice survey assessed the ...
Source: Archives de Pediatrie - August 3, 2015 Category: Pediatrics Authors: Chouraqui JP, Simeoni U, Tohier C, Nguyen F, Kempf C, Beck L, Lachambre E Tags: Arch Pediatr Source Type: research

Relationship between respiratory and food allergy and evaluation of preventive measures.
e of Spanish Society of Allergology, Clinical Immunology (SEAIC) 2010 Abstract Food allergy and respiratory allergy are two frequently associated diseases and with an increasing prevalence. Several reports show the presence of respiratory symptoms in patients with food allergy, while certain foods may be related to the development or exacerbation of allergic rhinitis and asthma. The present update focuses on this relationship, revealing a pathogenic and clinical association between food and respiratory allergy. This association is even more intense when the food hypersensitivity is persistent or starts in the earl...
Source: Allergologia et Immunopathologia - August 24, 2015 Category: Allergy & Immunology Authors: Vega F, Panizo C, Dordal MT, González ML, Velázquez E, Valero A, Sánchez MC, Rondón C, Montoro J, Matheu V, Lluch-Bernal M, González R, Fernández-Parra B, Del Cuvillo A, Dávila I, Colás C, Campo P, Antón E, Navarro AM, Rhinoconjunctivitis Committ Tags: Allergol Immunopathol (Madr) Source Type: research

Taking the leap earlier: the timing of tolerance
Purpose of review: The paradigm for the primary prevention of peanut allergy was, until recently, strict avoidance of peanut during pregnancy, infancy, and early childhood. However, in countries that had these dietary guidelines, the prevalence of peanut allergy greatly increased in contrast to low prevalence rates of peanut allergy in countries where infant diets included peanut at an early age, suggesting the hypothesis that early introduction of peanut is superior to delayed introduction of peanut as a strategy for the primary prevention of food allergy. This review examines recent high-quality studies that support this...
Source: Current Opinion in Pediatrics - November 10, 2015 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Talal Chatila Source Type: research

Update on Early Nutrition and Food Allergy in Children.
Abstract With growing evidence of an increase in the prevalence, food allergy has been emerged as a new public health problem. As treatment and management of food allergy remain challenging, more attention has been paid to the importance of prevention of food allergy. Although the exact mechanism of recent epidemic is not fully understood, it is suggested that nutritional exposure in early life may play an important role in food allergy development. The underlying hypothesis is that nutritional status or food exposure in the critical period of fetal development can affect the programming of immune system and modif...
Source: Yonsei Medical Journal - March 23, 2016 Category: Universities & Medical Training Authors: Lee SE, Kim H Tags: Yonsei Med J Source Type: research