Beyond Expert Opinion: A Comparison of Antibiotic Regimens for Infectious Urinary Tract Pathology in Pregnancy
Conclusion Receipt of antibiotics other than nitrofurantoin or SMZ-TMP for LUTI in pregnancy was not associated with increased risk of progression to pyelonephritis, PTB, or LBW. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - October 12, 2020 Category: Perinatology & Neonatology Authors: Krischak, Madison K. Rosett, Heather A. Sachdeva, Sarika Weaver, Kristin E. Heine, Robert Phillips Denoble, Anna E. Dotters-Katz, Sarah K. Tags: Original Article Source Type: research

Inpatient Biophysical Profiles and the Effect on Clinical Decision Making
AJP Rep 2020; 10: e357-e361 DOI: 10.1055/s-0040-1717141 Objective Our primary objective was to determine whether biophysical profiles (BPP) performed on the antepartum unit result in changes in clinical decision making. Study Design A retrospective cohort chart review was performed among women who had a BPP during hospital admission. BPP status was categorized as normal (8/8 points) and abnormal (6/8 or less points). The primary outcome, clinical decision making, was the need for prolonged external fetal monitoring (defined as > 2 hours) or decision to proceed with delivery. Secondar...
Source: American Journal of Perinatology Reports - October 12, 2020 Category: Perinatology & Neonatology Authors: Racusin, Diana A. Chauhan, Suneet P. Sibai, Baha Chen, Han-Yang Adimorah, Nesochi Piro, Mica Heye, Kristen Sharp, Charlotte WHNP-BC, MSN Blackwell, Sean Refuerzo, Jerrie Tags: Case Report Source Type: research

High Blood Pressure in a Urea Cycle Disorder: Case Report
Conclusion High blood pressure has been rarely described as a lead symptom for the debut of a UCD. We must take this into consideration as an early recognition and treatment of these disorders are of the utmost importance. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - October 6, 2020 Category: Perinatology & Neonatology Authors: Sol é, Carolina Arriaga, Mar ía Ca ñedo, Elvira Tags: Case Report Source Type: research

Mesenchymal Stem Cells Attenuate Lipopolysaccharide-Induced Inflammatory Response in Human Uterine Smooth Muscle Cells
Conclusion MSCs appear to play a role in significantly attenuating LPS-mediated inflammation via alteration of down-stream MAPKs. MSCs may represent a novel, cell-based therapy in women with increased risk of inflammatory-mediated preterm birth. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Mani, Arunmani Hotra, John W. Blackwell, Sean C. Goetzl, Laura Refuerzo, Jerrie S. Tags: Case Report Source Type: research

Correlation of Obesity with External Cephalic Version Success among Women with One Previous Cesarean Delivery
Conclusion There was no correlation of BMI with the rate of successful ECV among women with one prior cesarean delivery. Given the similar success rates of ECV and adverse outcomes, obese women with one prior cesarean delivery should be offered ECV. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: McLaren, Rodney Atallah, Fouad Fisher, Nelli Minkoff, Howard Tags: Case Report Source Type: research

Debunking the Myth: Do Maternal-Fetal Medicine Fellows Negatively Impact Resident Obstetrical Skills?
AJP Rep 2020; 10: e319-e323 DOI: 10.1055/s-0040-1715168 Objective Residency applicants often express concern that fellows negatively impact surgical opportunities, especially with less common procedures. We sought to describe the impact of maternal-fetal medicine (MFM) fellows on resident surgical opportunities. Study Design Anonymous 27-question e-survey sent to obstetrics and gynecology (OBGYN) residents in the United States and Puerto Rico in March 2018. Questions included experience as primary surgeon, for fourth year residents only, comfort performing procedures postresidency, and demographics. Residen...
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Dotters-Katz, Sarah K. Grace, Matthew Heine, R Phillips Propst, Katie Tags: Case Report Source Type: research

Establishing Better Evidence on Remote Monitoring for Postpartum Hypertension: A Silver Lining of the Coronavirus Pandemic
AJP Rep 2020; 10: e315-e318 DOI: 10.1055/s-0040-1715169The transformation of our health care system in response to coronavirus disease 2019 (COVID-19) provides a unique opportunity to examine the use of telehealth for postpartum care. The postpartum period can pose significant risks and challenges, particularly for women with hypertensive disorders of pregnancy. Remote blood pressure monitoring has proven feasible and acceptable among women and providers but has not been widely implemented or researched. Early studies have identified improved outcomes with use of telehealth, including increased compliance with care and dec...
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Sawyer, Michala R. Jaffe, Elana F. Naqvi, Mariam Sarma, Amy Barth, William H. Goldfarb, Ilona T. Tags: Case Report Source Type: research

Sleep Duration during Pregnancy using an Activity Tracking Device
AJP Rep 2020; 10: e309-e314 DOI: 10.1055/s-0040-1715172 Objective The aim of this study was to describe sleep duration across gestation in women who wore an activity-tracking device (ATD) during pregnancy, and to study the association between sleep duration and adverse maternal and neonatal outcomes Study Design Women ≥ 18 years old who owned a smartphone were approached to participate in 2016 to 2017. Participants received instructions to wear and sync an ATD daily. Steps, sedentary hours, and sleep duration were wirelessly transmitted via cellular technology. We measured sleep duration for the m...
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Kominiarek, Michelle A. Yeh, Chen Balmert, Lauren C. Facco, Francesca Grobman, William Simon, Melissa Tags: Case Report Source Type: research

Interdisciplinary Approach for the Medical Management of Gestational Gigantomastia
Conclusion We highlight a successful interdisciplinary medical management approach, which helped to avoid a morbid, intrapartum breast reduction. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Cabrera, Camila Radolec, Mackenzy Prescott, Angela De La Cruz, Carolyn Beck, Stacy Tags: Case Report Source Type: research

Late Presentation of Uterine Rupture Following Vaginal Birth After Cesarean Delivery: A Case Report
Conclusion Delivery after trial of labor after cesarean delivery usually decreases acuity; however, these patients remain at risk for significant complications. Clinicians should continue to assess patients in the immediate postpartum period and proceed with surgical intervention if necessary. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Choi, Lindsey A. Chung, Ariel A. Pierce, Brian Tags: Case Report Source Type: research

Fetal Macrocephaly: A Novel Sonographic Finding in Congenital Myotonic Dystrophy
Conclusion CDM should be included in the differential diagnosis of third-trimester macrocephaly, especially in the presence of additional sonographic clues and when maternal medical history and physical examination are suggestive of DM. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Shinar, Shiri Balakumar, Parry Shah, Vibhuti Chong, Karen Uster, Tami Chitayat, David Tags: Case Report Source Type: research

Infective Endocarditis as a Complication of Intravenous Drug Use in Pregnancy: A Retrospective Case Series and Literature Review
Conclusion Management of intravenous drug use-associated infective endocarditis in pregnancy involves more than treating the acute condition. In pregnant women with opioid use disorder and infective endocarditis, addiction and chronic psychosocial conditions need to be addressed to optimize care. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Adesomo, Adebayo Gonzalez-Brown, Veronica Rood, Kara M. Tags: Case Report Source Type: research

Response of an Obstetric Unit during the Coronavirus Disease of 2019 (COVID-19) Pandemic: Experiences from a Tertiary Care Center
Conclusion The COVID-19 pandemic has posed many unique challenges. Balancing communication, risks of infection to providers, patient autonomy and rights, and resources for testing and personal protective equipment were among the valuable lessons learnt. We have shared our experiences and described our observations and challenges in Westchester County, New York. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Kumaraswami, Sangeeta Pradhan, Tana S. Vrabie-Wolf, Sorana Lodhi, Sadaf Rajendran, Geetha P. Tedjarati, Sean S. Grimes, Cara L. Tags: Case Report Source Type: research

Bayes Theorem and Protopathic Bias: Methodological Concerns When Addressing the Impact of Fetal Heart Rate Patterns on the Cesarean Section Rate
AJP Rep 2020; 10: e342-e345 DOI: 10.1055/s-0040-1713786Over the last 30 years, the caesarean section rate has reached global epidemic proportions. This trend is driven by multiple factors, an important one of which is the use and inconsistent interpretation of the electronic fetal monitoring (EFM) system. Despite its introduction in the 1960s, the EFM has not definitively improved neonatal outcomes, yet it has since significantly contributed to a seven-fold increase in the caesarean section rate. As we attempt to reduce the caesarean rates in the developed world, we should consider focusing on areas that have garnered litt...
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Balayla, Jacques Lasry, Ariane Gil, Yaron Volodarsky-Perel, Alexander Tags: Original Article Source Type: research

Duration of the Third Stage of Labor and Estimated Blood Loss in Twin Vaginal Deliveries
Conclusion Twin pregnancy is a known risk factor for postpartum hemorrhage. As the duration of the third stage prolongs, the risk for hemorrhage also increases. We recommend delivery of the placenta in twin pregnancies by 15 minutes to reduce this risk. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Whittington, Julie R. Pagan, Megan Daugherty, Kristen Cummings, Kelly Ounpraseuth, Songthip T. Eads, Lauren Magann, Everett F. Tags: Original Article Source Type: research

Associations among Discharge Opioid Prescribing and Inpatient Postpartum Opioid Usage after Delivery
Conclusion The number of opioid tablets prescribed at discharge had no association with inpatient postpartum consumption after VD or CD. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 22, 2020 Category: Perinatology & Neonatology Authors: Veade, Ashley McKinnish, Tyler Carter, Ebony Lewkowitz, Adam Tags: Original Article Source Type: research

In Utero Vertical Transmission of Coronavirus Disease 2019 in a Severely Ill 29-week Preterm Infant
We present a case of likely intrauterine transmission of COVID-19 infection in a critically ill premature infant born to a COVID-19 infected mother and describing her clinical course thus far. The clinical presentation in the infant is consistent with COVID-19 infection described so far in literature along with positive PCR, and positive COVID-19 serology: immunoglobulin G, immunoglobulin M, and immunoglobulin A. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Sourc...
Source: American Journal of Perinatology Reports - September 15, 2020 Category: Perinatology & Neonatology Authors: Gupta, Arpit Malhotra, Yogangi Patil, Uday Muradas, Ana R. Lee, William T. Krammer, Florian Amanat, Fatima Clare, Camille A. Vinod, Suja Ghaly, Emad Tags: Case Report Source Type: research

Air Leak Syndrome in Two Very Preterm Infants Born to Mothers with Coronavirus Disease 2019: An Association or a Coincidence?
We present here two very preterm infants born to mothers with COVID-19, whose respiratory course was significant for initial mild respiratory distress syndrome who developed acute onset severe air leak syndrome at approximately 24 to 36 hours of age requiring thoracentesis. Their respiratory status improved gradually with resolution of air leak and respiratory failure by 2 weeks of age. Both infants tested negative for SARS-CoV-2 by reverse transcriptase–polymerase chain reaction of multiple respiratory specimens collected beyond 24 hours after birth. As the incidence of severe air leak syndrome is rela...
Source: American Journal of Perinatology Reports - September 1, 2020 Category: Perinatology & Neonatology Authors: Reddy, Ajay Engelhardt, Krystin Jain, Deepak Tags: Case Report Source Type: research

Neonatal Cerebellar Hemorrhage and Facial Nerve Palsy: An Unusual Association
We report the uncommon case of a late preterm infant born by spontaneous delivery who showed right peripheral facial palsy at 24 hours of life. Cranial ultrasound showed lateral ventricles dilatation and a diffuse hyperechoic round lesion in the right cerebellar hemisphere. The computed tomography scan confirmed a hemorrhagic lesion in the right cerebellar hemisphere and in the vermis with midline shift and intraventricular bleeding. Ommaya reservoir was inserted and used for a few days. The facial palsy gradually recovered to a complete remission after 6 weeks. Follow-up examinations at 12 and 18 months evidenced i...
Source: American Journal of Perinatology Reports - September 1, 2020 Category: Perinatology & Neonatology Authors: Coviello, Caterina Remaschi, Giulia Becciani, Sabrina Montano, Simona Corsini, Iuri Mussa, Federico Basile, Massimo Dani, Carlo Tags: Case Report Source Type: research

Implementation of a Postpartum Hemorrhage Safety Bundle at an Urban Safety-Net Hospital
Conclusion Keys to implementation included multidisciplinary stakeholder commitment, stepwise and iterative approach, and parallel systems for monitoring and evaluation Implementation of a PPH safety bundle is feasible in a resource-constrained setting. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 1, 2020 Category: Perinatology & Neonatology Authors: Joseph, Naima T. Worrell, Nikkia H. Collins, Janice Schmidt, Melanie Sobers, Grace Hutchins, Kathlyn Chahine, E. Britton Faya, Christine Lewis, Luanne Green, Victoria L. Castellano, Penny Z. Lindsay, Michael K. Tags: Case Report Source Type: research

Nasal High Frequency Oscillatory Ventilation for Respiratory Failure due to Respiratory Syncytial Virus Bronchiolitis: Case Report
AJP Rep 2020; 10: e253-e254 DOI: 10.1055/s-0040-1715179The authors describe a case of acute respiratory failure due to severe bronchiolitis. During high-flow nasal cannula ventilation, the blood's high levels of hypercapnia had taken them to plan the sedation and the orotracheal intubation. However, before attempting intubation, a nasal high frequency oscillatory ventilation cycle was performed and it led to a marked improvement in the blood gas, avoiding in this way the invasive ventilation. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents &nbs...
Source: American Journal of Perinatology Reports - August 26, 2020 Category: Perinatology & Neonatology Authors: Liberatore, Pio Maffei, Gianfranco Tags: Case Report Source Type: research

Carbetocin versus Oxytocin for the Prevention of Postpartum Hemorrhage in Cesarean Deliveries: A Retrospective Study of Two Consecutive Periods
Conclusion Carbetocin is not superior to oxytocin in preventing PPH. However, it does provide the advantage of requiring a single injection. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - August 26, 2020 Category: Perinatology & Neonatology Authors: Delorme, Pierre Kayem, Gilles Legardeur, H élène Roux-Dessarps, Louise Anne Girard, Guillaume Meunier, Geraldine Keita, Hawa Mandelbrot, Laurent Tags: Case Report Source Type: research

Use of Placental Growth Factor for Trisomy 21 Screening in Pregnancy: A Systematic Review
Conclusion Addition of PLGF to prenatal screening using serum analytes mildly improves trisomy 21 DRs as a function of FPRs. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - August 26, 2020 Category: Perinatology & Neonatology Authors: Badeghiesh, Ahmad Volodarsky-Perel, Alexander Lasry, Ariane Hemmings, Robert Gil, Yaron Balayla, Jacques Tags: Case Report Source Type: research

Safety and Efficacy of Higher Order Multifetal Pregnancy Reduction: A Single-Center Retrospective Study
Conclusion Perinatal outcomes were significantly improved by reducing the number of fetuses in higher order multifetal pregnancies. This study involved a large, diverse sample population, and the results can be used as a reference while conducting prenatal counseling. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - August 26, 2020 Category: Perinatology & Neonatology Authors: Liu, Yan Wang, Xie Tong Li, Hong Yan Hou, Hai Yan Wang, Hong Wang, Yan Tun Tags: Case Report Source Type: research

Driving Factors of Preterm Birth Risk in Adolescents
We examined rates of spontaneous and indicated preterm births (S-PTB and I-PTB, respectively) and clinical risk factors for PTB in adolescents. Study Design This is a population-based, retrospective cohort using 2012 U.S. natality data of nulliparous women who delivered a nonanomalous singleton birth between 20 and 42 weeks' gestation. Maternal age included
Source: American Journal of Perinatology Reports - August 26, 2020 Category: Perinatology & Neonatology Authors: Perez, Marta J. Chang, Jen J. Temming, Lorene A. Carter, Ebony B. L ópez, Julia D. Tuuli, Methodius G. Macones, George A. Stout, Molly J. Tags: Original Article Source Type: research

Coronavirus Disease 2019 in a Premature Infant: Vertical Transmission and Antibody Response or Lack Thereof
We present here a preterm neonate born to a critically ill mother with SARV-CoV-2 with early evidence of infection with a positive reverse transcription polymerase chain reaction on day 1. Lack of parental contact prior to testing and strict adherence to recommended airborne precautions perinatally suggest vertical transmission of infection. Critical maternal illness and medications may have contributed to the need for extensive resuscitation at birth and highlight the importance of close fetal monitoring. Infant lacked immunoglobulin G antibody response by 3 weeks, presumably secondary to mild clinical course and prematur...
Source: American Journal of Perinatology Reports - August 19, 2020 Category: Perinatology & Neonatology Authors: Rivera-Hernandez, Pedro Nair, Jayasree Islam, Shamim Davidson, Lauren Chang, Arthur Elberson, Valerie Tags: Case Report Source Type: research

Impact of Excess Weight Gain on Risk of Postpartum Infection in Class III Obesity
AJP Rep 2020; 10: e213-e216 DOI: 10.1055/s-0040-1715165 Objective To assess the impact of gestational weight gain>20 pounds (more than Institute of Medicine [IOM] recommendations) on postpartum infectious morbidity in women with class III obesity. Methods This is a retrospective cohort of term, nonanomalous singleton pregnancies with body mass index ≥40 at a single institution from 2013 to 2017. Pregnancies with multiple gestation, late entry to care, and missing weight gain data are excluded. Primary outcome is a composite of postpartum infection (endometritis, urinary tract, respiratory, and wound i...
Source: American Journal of Perinatology Reports - August 19, 2020 Category: Perinatology & Neonatology Authors: Mitchell, Courtney J. Adkins, LaMani Tucker, Ann Brown, Haywood Siegel, Anne Dotter-Katz, Sarah Tags: Case Report Source Type: research

The Association between Glucose Levels and Adverse Pregnancy Outcomes in Nondiabetic Twin Pregnancies
Conclusion In women with twin pregnancies without GDM, elevated maternal glucose levels are not associated with preeclampsia, cesarean delivery, or neonatal hypoglycemia. The altered physiology of twin gestations may modify the effect of maternal hyperglycemia on perinatal outcomes as compared with singleton pregnancies. Current approaches to screening for and treating GDM during pregnancy might not adequately account for these unique considerations among twins. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract&nb...
Source: American Journal of Perinatology Reports - August 19, 2020 Category: Perinatology & Neonatology Authors: Cheung, Kevin Fox, Nathan S. Tags: Original Article Source Type: research

Labetalol-Induced Hepatotoxicity during Pregnancy: A Case Report
Conclusion Labetalol-induced hepatitis should be considered in the differential for transaminitis during pregnancy to prevent iatrogenic preterm delivery. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - August 3, 2020 Category: Perinatology & Neonatology Authors: Whelan, Anna Izewski, Joanna Berkelhammer, Charles Walloch, Jami Kay, Helen H. Tags: Case Report Source Type: research

Methadone for Opioid Use Treatment during Pregnancy: Trends in Postpartum Dose Adjustments
Conclusion Patients using methadone for OUT during pregnancy achieved minimal dose decreases postpartum. Patients should be counseled that postpartum dose tapers may be challenging and about alternatives to methadone for OUT. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - August 3, 2020 Category: Perinatology & Neonatology Authors: Ward, Clara Christensen, Carl W. Tags: Original Article Source Type: research

Effectiveness of Progestogens as Maintenance Tocolysis and Urogenital Cultures: Secondary Analysis of the PROTECT Trial
Conclusion Among women with negative urine culture, the rate of preterm birth
Source: American Journal of Perinatology Reports - August 3, 2020 Category: Perinatology & Neonatology Authors: Pignatti, Lucrezia D'Amico, Roberto Vergani, Patrizia Di Tommaso, Mariarosaria Acaia, Barbara Benedetto, Chiara Facchinetti, Fabio Tags: Original Article Source Type: research

Hospitalization Duration Following Uncomplicated Cesarean Delivery: Predictors, Facility Variation, and Outcomes
This study was designed to: (1) characterize stay duration following cesarean delivery, (2) ascertain whether facility variation exists, and (3) determine whether shorter stays are associated with rates of readmission or costs. Study Design The 2017 Nationwide Readmissions Database was used to identify uncomplicated cesarean deliveries. Hierarchical logistic regression was used to assess for facility variation in percentage of patients discharged within 2 days. Similar models were used to assess for associations between probability of readmission within 30 days and facility-level rates of discharge within 2 days. ...
Source: American Journal of Perinatology Reports - June 18, 2020 Category: Perinatology & Neonatology Authors: Federspiel, Jerome J. Suresh, Sunitha C. Darwin, Kristin C. Szymanski, Linda M. Tags: Case Report Source Type: research

Redefining Second Stage of Labor: Number of Pushing Contractions
AJP Rep 2020; 10: e183-e186 DOI: 10.1055/s-0040-1709982 Introduction Despite time standards for second stage labor, “delayed pushing,” uterine contraction frequency, and alternate contraction pushing may alter the effective maternal effort. We sought to quantify the number of pushing contractions needed for a spontaneous vaginal delivery (SVD) among primipara and multipara patients. Methods Deliveries at Harbor-UCLA Medical Center in 2017 were selected for SVD of singleton, term newborns. The first 100 primipara and 100 multipara deliveries were analyzed and monitor tracings quantified for pushi...
Source: American Journal of Perinatology Reports - June 18, 2020 Category: Perinatology & Neonatology Authors: Bok, Serin M. Carmona, Gabriela E. Pena Crawford, Jake Eskander, Ramy Desai, Mina Ross, Michael G. Tags: Case Report Source Type: research

COVID-19 and HELLP: Overlapping Clinical Pictures in Two Gravid Patients
Conclusion Clinicians are encouraged to consider both of these diagnoses when caring for pregnant women during the COVID-19 pandemic to assure that both maternal and fetal concerns are addressed and treated appropriately. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 17, 2020 Category: Perinatology & Neonatology Authors: Futterman, Itamar Toaff, Miriam Navi, Liel Clare, Camille A. Tags: Case Report Source Type: research

Cell-Free DNA as an Addition to Ultrasound for Screening of a Complete Hydatidiform Mole and Coexisting Normal Fetus Pregnancy: A Case Report
Conclusion In atypical cases, cell-free DNA may be useful in evaluation of molar pregnancy. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 17, 2020 Category: Perinatology & Neonatology Authors: Gabra, Martina G. Gonzalez, Maritza G. Bullock, Holly N. Hill, Meghan G. Tags: Case Report Source Type: research

Acute Respiratory Decompensation Requiring Intubation in Pregnant Women with SARS-CoV-2 (COVID-19)
AJP Rep 2020; 10: e169-e175 DOI: 10.1055/s-0040-1712925There is a current paucity of information about the obstetric and perinatal outcomes of pregnant novel coronavirus disease 2019 (COVID-19) patients in North America. Data from China suggest that pregnant women with COVID-19 have favorable maternal and neonatal outcomes, with rare cases of critical illness or respiratory compromise. However, we report two cases of pregnant women diagnosed with COVID-19 in the late preterm period admitted to tertiary care hospitals in New York City for respiratory indications. After presenting with mild symptoms, both quickly developed w...
Source: American Journal of Perinatology Reports - June 3, 2020 Category: Perinatology & Neonatology Authors: Silverstein, Jenna S. Limaye, Meghana A. Brubaker, Sara G. Roman, Ashley S. Bautista, Judita Chervenak, Judith Ratner, Adam J. Sommer, Philip M. Roselli, Nicole M. Gibson, Charlisa D. Ellenberg, David Penfield, Christina A. Tags: Case Report Source Type: research

Heart Failure with Preserved Ejection Fraction in a Postpartum Patient with Superimposed Preeclampsia and COVID-19
We present a case from March 2020 of a 25-year-old G2P2002 whose delivery was complicated by preeclampsia with severe features who presented to the emergency department 9 days after cesarean delivery with chest tightness and dyspnea on exertion. On presentation she had severe hypertension, pulmonary edema, elevated brain natriuretic peptide, and high-sensitivity troponin-I, suggesting a diagnosis of hypertensive emergency leading to heart failure with a preserved ejection fraction resulting in pulmonary edema and abnormal cardiac screening tests. However, bilateral opacities were seen on a computed tomography of the chest,...
Source: American Journal of Perinatology Reports - June 3, 2020 Category: Perinatology & Neonatology Authors: Sinkey, Rachel G. Rajapreyar, Indranee Robbins, Lindsay S. Dionne-Odom, Jodie Pogwizd, Steven M. Casey, Brian M. Tita, Alan T.N. Tags: Case Report Source Type: research

Risk Factors for Postpartum Maternal Infection Following Spontaneous Vaginal Delivery Complicated by Chorioamnionitis
AJP Rep 2020; 10: e159-e164 DOI: 10.1055/s-0040-1709983 Objective Guidelines for the management of chorioamnionitis include intrapartum antibiotics, while postpartum antibiotics after spontaneous vaginal delivery (SVD) are reserved high-risk women. Our objective is to describe the incidence of and risk factors for postpartum infection after SVD complicated by chorioamnionitis. Study Design This is a retrospective study of SVDs with clinically diagnosed chorioamnionitis at a single center. The primary outcome was a composite of postpartum infection. Women who developed the primary outcome were compared with ...
Source: American Journal of Perinatology Reports - May 14, 2020 Category: Perinatology & Neonatology Authors: Daifotis, Helen A. Smith, Megan M. Denoble, Anna E. Dotters-Katz, Sarah K. Tags: Case Report Source Type: research

The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia —A Case Series
Conclusion The Carit maneuver is an original and successful intervention in the management of shoulder dystocia unresponsive to McRobert's maneuver and suprapubic pressure. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: Gei, Alfredo F Mastache, Jorge Suarez Pacheco, Luis D. Villanueva, Mariana Tags: Original Article Source Type: research

Antibiotic Prophylaxis Trials in Obstetrics: A Call for Pediatric Collaboration
AJP Rep 2020; 10: e155-e158 DOI: 10.1055/s-0040-1709513Surgical site infections are common complications of cesarean delivery. Many recent studies, including meta-analyses, have assessed the efficacy of antibiotic prophylaxis. Those articles have demonstrated that preincision antibiotic prophylaxis reduces the incidence of surgical site infections postcesarean, and that the use of adjunctive azithromycin further reduces infection after nonelective cesarean deliveries. However, long-term effects of fetal exposure to antibiotic prophylaxis—including asthma, obesity, and alterations in microbiota—have also been de...
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: McLaren, Rodney A. Atallah, Fouad Minkoff, Howard Tags: Case Report Source Type: research

Applying a Prediction Model for Vaginal Birth after Cesarean to a Latina Inner-City Population
Conclusion Our results question whether Latina ethnicity should continue to be considered a negative predictive factor for VBAC success. Our results also suggest that Latinas with a low predicted VBAC success should not necessarily be discouraged from attempting TOLAC. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: Nguyen, Michelle T. Hayes-Bautista, Teodocia Maria Hsu, Paul Bragg, Christina Chopin, Irving Shaw, Kathryn J. Tags: Case Report Source Type: research

Perinatal Hypophosphatasia in a Premature Infant
AJP Rep 2020; 10: e139-e147 DOI: 10.1055/s-0040-1709512A premature male infant was delivered at 32 weeks' gestation due to category-2 fetal tracing after preterm labor. The physical exam showed shortened and bowed long bones, with calvarium felt in small area of the head. Serum alkaline phosphatase was very low on admission. Extensive metaphyseal abnormalities, bowing of long bones, and poor ossification of all bones were noted on skeletal survey (radiography). Based on ultrasound evidence of “bowing” and long bone fractures at 26 weeks, amniocentesis was performed that later diagnosed hypophosphatasia by genet...
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: Sankaran, Deepika Chandrasekharan, Praveen K. Rawat, Munmun Tags: Case Report Source Type: research

Peritoneovaginal Fistula and Appendicitis-Related Pelvic Abscess in Pregnancy
AJP Rep 2020; 10: e129-e132 DOI: 10.1055/s-0040-1708849Appendicitis in pregnancy is the most common nonobstetric surgical emergency. Pregnancy causes changes in anatomy, which could lead to uncertainty regarding the diagnosis of appendicitis. This case report describes a case of appendicitis presenting with peritoneovaginal fistula in a pregnant woman in the second trimester, with interesting finding of isolated appendiceal endometriosis on pathology. The importance of complete physical examination, including speculum examination, is emphasized in the pregnant patient presenting with acute-onset abdominal pain. Imaging cri...
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: Saleh, Mona Kim, Antonia Francis Gardner, Andrew Sun, Katherine Brubaker, Sara Tags: Case Report Source Type: research

Hepatitis C Virus Infection in Children and Pregnant Women: An Updated Review of the Literature on Screening and Treatments
Conclusion To improve public health, universal screening of pregnant women for HCV infection should be performed. Early identification of women and children with HCV infection is important to enable them to be included in assessment and/or treatment programs. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - March 30, 2020 Category: Perinatology & Neonatology Authors: Ragusa, Rosalia Corsaro, Liberato Simone Frazzetto, Evelise Bertino, Emanuele Bellia, Maria Alessandra Bertino, Gaetano Tags: Case Report Source Type: research

Smith –Lemli–Opitz's Syndrome as a Possible Cause of Recurrent Pregnancy Loss: A Case Report
AJP Rep 2020; 10: e118-e120 DOI: 10.1055/s-0040-1705131Based on the known carrier frequency of Smith–Lemli–Opitz's syndrome (SLOS), the prevalence of this disease should be significantly higher than what is observed in the population. This may be due to a higher rate of pregnancy loss in affected embryos. Here, we present the case of a couple who underwent expanded carrier screening (ECS) after experiencing three first trimester pregnancy losses. Both parents were found to be carriers of SLOS mutations, and DNA analysis of the fetal remains of the third loss revealed the aborted fetus had inherited both the mat...
Source: American Journal of Perinatology Reports - March 30, 2020 Category: Perinatology & Neonatology Authors: Mitra, Anjali Dolitsky, Shelley Yadava, Stacy Ashkinadze, Elena Tags: Case Report Source Type: research

Unique Clinical and Histological Features of Placental Mesenchymal Dysplasia Complicated by Severe Preeclampsia in the Midtrimester
AJP Rep 2020; 10: e113-e117 DOI: 10.1055/s-0040-1709186Detailed clinical and pathological features of placental mesenchymal dysplasia (PMD) complicated by preeclampsia (PE) are unknown. A 39-year-old nulliparous woman was referred at 19 weeks gestation. Ultrasound examination identified a fetus with severe growth restriction (−2.8 SD) and a markedly thickened placenta with many cystic structures suggestive of PMD. At 21 weeks, the patient developed severe hypertension (180/95 mm Hg) with marked proteinuria and an elevated serum soluble fms-like tyrosine-kinase-1 (sFlt-1) level (47,000 pg/L). The pregnancy was ...
Source: American Journal of Perinatology Reports - March 27, 2020 Category: Perinatology & Neonatology Authors: Kuwabara, Yoshimitsu Yonezawa, Mirei Kubota, Yumene Ichikawa, Tomoko Ohashi, Ryuji Takeshita, Toshiyuki Tags: Case Report Source Type: research

Efficacy of Prophylactic Antibiotics in Bakri Intrauterine Balloon Placement: A Single-Center Retrospective Analysis and Literature Review
Conclusion Our protocol might be effective and sufficient in preventing postpartum BIUB placement-related endometritis. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - March 18, 2020 Category: Perinatology & Neonatology Authors: Nagase, Yoshikazu Matsuzaki, Shinya Kawanishi, Yoko Nakagawa, Satoshi Kakigano, Aiko Takiuchi, Tsuyoshi Mimura, Kazuya Tomimatsu, Takuji Endo, Masayuki Kimura, Tadashi Tags: Original Article Source Type: research

How Reliable Is a Statewide Prescription Monitoring Program for Identifying Post-Cesarean Opioid Use?
Conclusion Nearly half of women who underwent a cesarean section and who were administered opioids 24 hours prior to discharge did not have a detectable postpartum opioid prescription in the PMP. While identification of prescription filling improved with time, many of women were not detectable in the PMP system. These data call into question the accuracy of PMPs in identifying prescription opioid filling patterns in the postpartum setting. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  | ...
Source: American Journal of Perinatology Reports - March 18, 2020 Category: Perinatology & Neonatology Authors: Premkumar, Ashish Speedy, Sedona E. Miller, Emily S. Tags: Original Article Source Type: research

Abortion for Fetal Genetic Abnormalities: Type of Abnormality and Gestational Age at Diagnosis
Conclusion Most abortions were for abnormalities that can be suspected early in pregnancy. As many structural abnormalities associated with rare conditions are not identifiable until the mid-trimester, prenatal diagnosis and abortion occurred significantly later. Physicians and patients should be aware of the limitations of genetic screening. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - March 15, 2020 Category: Perinatology & Neonatology Authors: Grossman, Tracy B. Chasen, Stephen T. Tags: Original Article Source Type: research

Electronic Fetal Monitoring Credentialing Examination: The First 4000
Conclusion The PQF FMC exam is a reliable, valid assessment of both Electronic Fetal Monitoring (EFM) knowledge and judgment. It evaluates essential EFM skills for the establishment of practical credentialing. It also reports modest correlation between knowledge and judgment scores, suggesting that knowledge alone does not assure clinical competency. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - March 15, 2020 Category: Perinatology & Neonatology Authors: Tomlinson, Mark W. Brumbaugh, Sara A. O'Keeffe, Marin Berkowitz, Richard L. D'Alton, Mary Nageotte, Michael Tags: Case Report Source Type: research