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Condition: Atrial Fibrillation
Therapy: Statin Therapy
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Total 237 results found since Jan 2013.
Association between cardiovascular disease, cardiovascular drug therapy, and in-hospital outcomes in patients with COVID-19: data from a large single-center registry in Poland
CONCLUSION: Among cardiovascular risk factors and diseases, HF and DM appeared to increase in-hospital COVID-19 mortality, whereas the use of cardiovascular drugs was associated with lower mortality.PMID:33926173 | DOI:10.33963/KP.15990
Source: Kardiologia Polska - April 30, 2021 Category: Cardiology Authors: Micha ł Terlecki Wiktoria Wojciechowska Marek Klocek Agnieszka Olszanecka Katarzyna Stolarz-Skrzypek Tomasz Grodzicki Maciej Ma łecki Barbara Katra Aleksander Garlicki Monika Boci ąga-Jasik Krzysztof S ładek Andrzej Matyja Jerzy Wordliczek Agnieszka S Source Type: research
Prestroke Statins Improve Prognosis of Atrial Fibrillation-Associated Stroke through Increasing Suppressor of Cytokine Signaling-3 Levels
Conclusion: Our data suggested that the prestroke use of statins improved the clinical outcomes in AIS patients with AF by upregulating the level of SOCS-3 and reducing the plasma MMP-9 level.Eur Neurol
Source: European Neurology - March 8, 2021 Category: Neurology Source Type: research
Accelerated FEV1 decline and risk of cardiovascular disease and mortality in a primary care population of COPD patients
Accelerated lung function decline has been associated with increased risk of cardiovascular disease (CVD) in a general population, but little is known about this association in chronic obstructive pulmonary disease (COPD). We investigated the association between accelerated lung function decline and CVD outcomes and mortality in a primary care COPD population.
COPD patients without a history of CVD were identified in the Clinical Practice Research Datalink (CPRD)-GOLD primary care dataset (n=36 382). Accelerated decline in forced expiratory volume in 1 s (FEV1) was defined using the fastest quartile of the COPD popula...
Source: European Respiratory Journal - March 4, 2021 Category: Respiratory Medicine Authors: Whittaker, H. R., Bloom, C., Morgan, A., Jarvis, D., Kiddle, S. J., Quint, J. K. Tags: COPD and smoking Original Articles: COPD Source Type: research
Prevalence of Guideline-Directed Medical Therapy for Cardiovascular Disease Among Baltimore City Adults in the Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) Study
ConclusionsAmong an urban-dwelling population of adults, the use of secondary prevention of CVD was low, with lower aspirin and combination GDMT for Black participants with CAD. Efforts to improve GDMT use at the patient and provider levels may be needed to improve morbidity and mortality and reduce disparities in CVD.
Source: Journal of Racial and Ethnic Health Disparities - February 16, 2021 Category: International Medicine & Public Health Source Type: research
Commentary: Untangling the Mystery of Statin Therapy in Treating Postoperative Atrial Fibrillation: Does the Underlying Cardiac Pathology Matter?
Atrial fibrillation (AF) is an important and common complication following cardiac surgery and is associated prolonged hospital stay, and increased perioperative and long term risk of stroke and mortality.1 Its adverse impact carries across all types of cardiac surgical procedures including surgical septal myectomy for hypertrophic cardiomyopathy with left ventricular outflow tract obstruction.2 The cause of perioperative AF is incompletely understood, but pre-existing structural changes to the heart, particularly increased left atrial volume, sympathetic activation, and perioperative inflammation are considered important contributors.
Source: Seminars in Thoracic and Cardiovascular Surgery - February 15, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Francis D. Pagani Tags: ADULT – Commentary Source Type: research
The REDUCE-IT verdict on eicosapentaenoic acid and cardiovascular outcome challenged with STRENGTH
Key pointsSTRENGTH,1 an industry-sponsored, double-blind, randomized, controlled trial investigated the effects of a carboxylic acid (CA) formulation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (omega-3 CA) vs. corn oil in 13 078 participants with high cardiovascular (CV) risk, hypertriglyceridaemia, and low levels of high-density lipoprotein cholesterol.Eligible patients were randomized to receive 4 g/day of omega-3 CA or corn oil in addition to standard preventive therapies, including statins (high-intensity in 50%), renin-angiotensin-aldosterone system (RAAS) blockers (in 81%), and antiplatelet agents ...
Source: European Heart Journal - February 1, 2021 Category: Cardiology Source Type: research
Study: Fish Oil Doesn ’ t Seem To Prevent Heart Problems
This study is consistent with earlier trials.
The US Food and Drug Administration approved the fish oil-based drug Vascepa for heart attack and stroke prevention in 2019.
Nissen hopes the FDA will take a look at these studies and reconsider that decision.
“But it’s hard to get something undone once the genie gets out of the bottle,” he said.
An editorial in the journal that accompanies the study written by Dr. Gregory Curfman, assistant professor of medicine at Harvard Medical School, also suggested the FDA should require a postmarketing clinical trial of a high-dose of fish oil, such as Vascepa, vs. corn...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 16, 2020 Category: Consumer Health News Authors: CBS Boston Tags: Boston News Health Syndicated CBSN Boston CNN fish oil Source Type: news
Stroke in cardiac sarcoidosis: Need to worry?
CONCLUSIONS: Ischemic stroke in patients with CS can be attributed to a cardioembolic phenomenon. A high index of clinical suspicion is needed for early diagnosis and management of these patients.PMID:33189209 | PMC:PMC7670250 | DOI:10.1016/j.ihj.2020.07.015
Source: Indian Heart J - November 15, 2020 Category: Cardiology Authors: Muthiah Subramanian Sachin Yalagudri Daljeet Saggu Jugal Kishore Muralidhar Reddy Calambur Narasimhan Source Type: research
Multimorbidity in Patients With Acute Coronary Syndrome Is Associated With Greater Mortality, Higher Readmission Rates, and Increased Length of Stay: A Systematic Review
Conclusions
Multimorbid patients with ACS are at a greater risk for worse outcomes than their nonmultimorbid counterparts. Lack of consistent measurement makes interpretation of the impact of multimorbidity challenging and emphasizes the need for more research on multimorbidity's effects on postdischarge healthcare utilization.
Source: Journal of Cardiovascular Nursing - October 21, 2020 Category: Nursing Tags: Feature Article/Online Only Source Type: research
Statin Effects in Atrial Fibrillation-Related Stroke: A Systematic Review and Meta-Analysis
Conclusions: Statin therapy for AF-related stroke may reduce all-cause mortality and improve functional outcomes. Randomized controlled studies are warranted to confirm the effects of statins on the outcomes of AF-related stroke.
Source: Frontiers in Neurology - October 9, 2020 Category: Neurology Source Type: research
Statins Use and Outcome of Acute Ischemic Stroke Patients after Systemic Thrombolysis
Conclusion: Our study does not show any significant association between risk of sICH and poor outcome after IVT for patients on prior statin therapy. We also did not find significant association between the risk of sICH and poor outcome after IVT and the intensity of the stain used.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 14, 2020 Category: Neurology Source Type: research
Multimorbidity in Patients With Acute Coronary Syndrome Is Associated With Greater Mortality, Higher Readmission Rates, and Increased Length of Stay: A Systematic Review.
CONCLUSIONS: Multimorbid patients with ACS are at a greater risk for worse outcomes than their nonmultimorbid counterparts. Lack of consistent measurement makes interpretation of the impact of multimorbidity challenging and emphasizes the need for more research on multimorbidity's effects on postdischarge healthcare utilization.
PMID: 32925234 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Nursing - September 8, 2020 Category: Nursing Authors: Breen K, Finnegan L, Vuckovic K, Fink A, Rosamond W, DeVon HA Tags: J Cardiovasc Nurs Source Type: research
Stroke in cardiac sarcoidosis: Need to worry?
CONCLUSIONS: Ischemic stroke in patients with CS can be attributed to a cardioembolic phenomenon. A high index of clinical suspicion is needed for early diagnosis and management of these patients.
PMID: 33189209 [PubMed - in process]
Source: Indian Heart J - September 1, 2020 Category: Cardiology Authors: Subramanian M, Yalagudri S, Saggu D, Kishore J, Reddy M, Narasimhan C Tags: Indian Heart J Source Type: research
Multi-proteomic approach to predict specific cardiovascular events in patients with diabetes and myocardial infarction: findings from the EXAMINE trial
ConclusionsThe addition of multi-proteomic biomarkers to a clinical model in this population with diabetes and a recent MI allowed a better risk prediction and event reclassification, potentially helping for better risk assessment and targeted treatment decisions.Graphic abstractT2D type 2 diabetes,MI myocardial infarction,CV cardiovascular,HFH heart failure hospitalization,Δ delta,cNRI continuous net reclassification index,BNP brain natriuretic peptide,TRAILR2 trail receptor 2 (or death receptor 5),Gal-9 galectin-9,FGF23 fibroblast growth factor 23.
Source: Clinical Research in Cardiology - August 12, 2020 Category: Cardiology Source Type: research
Acute ischemic stroke management in Lebanon: obstacles and solutions.
This study assesses the current practices of physicians in Lebanon routinely involved in ischemic stroke (IS) management. We conducted a prospective observational study of patients hospitalized at 8 different Lebanese hospitals in the period August 1, 2015 to July 31, 2016, with a diagnosis of acute stroke. Baseline characteristics and data on diagnostic studies, as well as treatments received during hospitalization and at discharge, were collected and analyzed. Two hundred and three strokes/transient ischemic attacks (TIAs) were recorded but only 173 patients (85%) with ischemic events were included in the study. The pati...
Source: Functional Neurology - May 27, 2020 Category: Neurology Tags: Funct Neurol Source Type: research
