Filtered By:
Specialty: Neuroscience
Condition: Thrombosis

This page shows you your search results in order of relevance. This is page number 11.

Order by Relevance | Date

Total 164 results found since Jan 2013.

Neurologic complications in children under five years with Sickle Cell Disease
ConclusionNeurologic complications in children under five years of age with SCD may be more frequent than currently reported, among which Silent cerebral infarct and cognitive impairment are the most common.
Source: Neuroscience Letters - April 28, 2019 Category: Neuroscience Source Type: research

The diagnostic utility of routine clot analysis after endovascular thrombectomy in a patient with systemic lupus erythematosus and antiphospholipid syndrome
We present a case demonstrating histopathological clot findings after endovascular thrombectomy for acute ischaemic stroke in a 38 year-old male with systemic lupus erythematosus and antiphospholipid syndrome (APS). The differential diagnosis was embolism of a suspected Libman-Sacks vegetation or less likely an in-situ thrombosis. Clot analysis provided guidance with patient management and anticoagulation was commenced. The utility of clot analysis in this case provides support for routine clot analysis, which has been standard practice at our institution, and is likely to evolve as endovascular thrombectomy becomes more widely accessible.
Source: Journal of Clinical Neuroscience - September 18, 2019 Category: Neuroscience Source Type: research

Role of pericyte-derived SENP1 in neuronal injury after brain ischemia.
CONCLUSIONS: Our findings revealed that targeting SENP1 in pericytes may represent a novel therapeutic strategy for neurovascular protection in stroke. PMID: 32495523 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - June 3, 2020 Category: Neuroscience Authors: Sun M, Chen X, Yin YX, Gao Y, Zhang L, Chen B, Ji Y, Fukunaga K, Han F, Lu YM Tags: CNS Neurosci Ther Source Type: research

Occludin degradation makes brain microvascular endothelial cells more vulnerable to reperfusion injury in vitro
AbstractIntracerebral hemorrhage is the most dangerous complication in tPA thrombolytic therapy for ischemic stroke, which occurs as a consequence of endothelial cell death at the blood brain barrier (BBB) during thrombolytic reperfusion. We have previously shown that cerebral ischemia induced rapid occludin degradation and BBB disruption. Here we demonstrated an important role of occludin degradation in facilitating the evolution of ischemic endothelial cells towards death. Cultured brain microvascular endothelial cells (bEnd.3 cells) were exposed to oxygen ‐glucose deprivation (OGD) or incubated with occludin siRNA or ...
Source: Journal of Neurochemistry - June 11, 2020 Category: Neuroscience Authors: Yuan Zhang, Xiaofeng Li, Shanshan Qiao, Dexin Yang, Zongyang Li, Ji Xu, Weiping Li, Li Su, Wenlan Liu Tags: ORIGINAL ARTICLE Source Type: research

Inhibition of PI3Kγ by AS605240 plus low-dose tissue plasminogen activator (tPA) combination improves thrombolytic therapy in a rat model of embolic stroke
Publication date: Available online 31 August 2020Source: Neuroscience LettersAuthor(s): Rong Jin, Wei Zhong, Shan Liu, Min Wang, Guohong Li
Source: Neuroscience Letters - September 1, 2020 Category: Neuroscience Source Type: research

The potential role of microvascular pathology in the neurological manifestations of coronavirus infection
We present the hypothesis that pre-existing vascular damage (due to aging, cardiovascular disease, diabetes, hypertension or other conditions) facilitates infiltration of the virus into the central nervous system (CNS), increasing neuro-inflammation and the likelihood o f neurological symptoms. We also discuss the role of a neuroinflammatory cytokine profile in both blood–brain barrier dysfunction and macrovascular disease (e.g. ischemic stroke and thromboembolism). Future studies are needed to better understand the involvement of the microvasculature in coronavi rus neuropathology, and to test the diagnostic potential o...
Source: Fluids and Barriers of the CNS - September 9, 2020 Category: Neuroscience Source Type: research

Endovascular strategies for stroke management after subacute in-stent thrombosis
Publication date: November 2020Source: Journal of Clinical Neuroscience, Volume 81Author(s): Giancarlo Saal-Zapata, Walter Durand, Basavaraj V. Ghodke, Melanie Walker
Source: Journal of Clinical Neuroscience - September 26, 2020 Category: Neuroscience Source Type: research

Intra-arterial thrombolytic therapy for acute anterior spinal artery stroke
Publication date: Available online 24 December 2020Source: Journal of Clinical NeuroscienceAuthor(s): Joseph Haynes, Maksim Shapiro, Eytan Raz, Barry Czeisler, Erez Nossek
Source: Journal of Clinical Neuroscience - December 25, 2020 Category: Neuroscience Source Type: research

Cerebral venous sinus thrombosis in children: A study from a tertiary care hospital of eastern India
Conclusion: CVST is an underdiagnosed but important cause of stroke in childhood, occurring most often in the neonatal period. Mortality and morbidity are significant. Infections hyper coagulative disorders are the two primary associations. Magnetic resonance venography is the investigation of choice. Early diagnosis with management along with plan for secondary prevention can save from catastrophic consequences.
Source: Journal of Pediatric Neurosciences - January 19, 2021 Category: Neuroscience Authors: Shubhankar Mishra Ashok K Mallick Geeta Mohanty Priyabrata Nayak Source Type: research

Neuropsychiatric Symptoms of COVID-19 Explained by SARS-CoV-2 Proteins ’ Mimicry of Human Protein Interactions
Conclusion: SARS-CoV-2-human protein interactions may lead to the development of delirium, psychosis, seizures, encephalitis, stroke, sensory impairments, peripheral nerve diseases, and autoimmune disorders. Our findings are also supported by the previous in vivo and in vitro studies from other viruses. Further in vivo and in vitro studies using the proteins that are pointed here, could pave new targets both for avoiding and reversing neuropsychiatric presentations.
Source: Frontiers in Human Neuroscience - March 23, 2021 Category: Neuroscience Source Type: research

Evidence of Coronavirus (CoV) Pathogenesis and Emerging Pathogen SARS-CoV-2 in the Nervous System: A Review on Neurological Impairments and Manifestations
AbstractThe coronavirus disease 2019 (COVID-19) pandemic is an issue of global significance that has taken the lives of many across the world. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for its pathogenesis. The pulmonary manifestations of COVID-19 have been well described in the literature. Initially, it was thought to be limited to the respiratory system; however, we now recognize that COVID-19 also affects several other organs, including the nervous system. Two similar human coronaviruses (CoV) that cause severe acute respiratory syndrome (SARS-CoV-1) and Middle East respirator...
Source: Journal of Molecular Neuroscience - November 1, 2021 Category: Neuroscience Source Type: research

Evaluation of mean platelet volume and platelet count in ischemic stroke and its subtypes: focus on degree of disability and thrombus formation
.
Source: International Journal of Neuroscience - September 5, 2022 Category: Neuroscience Authors: Abhilash Ludhiadch Pooja Yadav Sunil Kumar Singh Sulena   Anjana Munshi Source Type: research

Carvedilol reduces the Neuronal apoptosis after ischemic stroke by modulating ATF3 expression in vitro
In conclusion, Carvedilol may be a key compound targeting ATF3 in OGD/R-PC12 cells.
Source: Developmental Neuroscience - October 11, 2022 Category: Neuroscience Source Type: research