Neurologic complications in children under five years with Sickle Cell Disease

ConclusionNeurologic complications in children under five years of age with SCD may be more frequent than currently reported, among which Silent cerebral infarct and cognitive impairment are the most common.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research

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Objectives: To determine the feasibility and impact of real-time anti-factor Xa (aFXa) level monitoring and enoxaparin dose adjustment in orthopaedic trauma. To examine the adequacy of standard fixed-dose enoxaparin chemoprophylaxis and to examine whether patient-specific factors influence enoxaparin metabolism. Design: Prospective cohort. Setting: Academic Level-I trauma center. Patients: Postoperative adult orthopaedic trauma patients undergoing acute fracture or nonunion surgery of the pelvis, acetabulum, or lower extremity placed on 30 mg of enoxaparin twice daily. Intervention: Peak steady-state aFXa lev...
Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
We report the psychiatric, behavioral, and cognitive profiles over the course of disease from a large, prospectively-enrolled, longitudinal cohort of children with CECTS. We further characterize the detailed seizure course and test the relationship between several proposed risk factors and neuropsychiatric and seizure outcomes in these children.MethodsPatients diagnosed with CECTS were enrolled as part of a community-based study and followed from diagnosis through disease resolution (16.0 ± 3.1 years, N = 60). Twenty sibling controls were also recruited. We report the natural history of premorbid neuropsyc...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
In conclusion, CWE seem to benefit from interventions and behavior modification techniques first developed for children with ADHD.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
ConclusionsDiffuse lesions may help to predict the poor neurological outcomes in patients with TSC.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
We present the first quantitative comparison of simultaneously acquired clinical and mobile consumer-grade EEG for a clinical use-case.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
This study was conducted with 210 hospital staff working at Van Regional Educational and Training Hospital in Van, Turkey. Data regarding the demographics and familiarity with epilepsy were obtained. Epilepsy knowledge scale and epilepsy attitude scale were used to evaluate the level of knowledge and attitudes regarding epilepsy, respectively.ResultsThe mean score of epilepsy knowledge scale was 11.3 ± 3.8 and the mean score of epilepsy attitude scale was 58.2 ± 6.3. The level of knowledge was positively associated with being familiar with epilepsy. Positive attitudes regarding epilepsy correlated wit...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
ConclusionThis study suggests a lower search interest over time in epilepsy surgery, and various associated terms, with increased interest in vagus nerve stimulation and laser ablation procedures over time. There is no clear indication from these data regarding the apparent shift from mesial temporal cases to an increase in extratemporal case workload.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
This article is part of the Special Issue “NEWroscience 2018”
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
AbstractEpilepsy self-management practices enhance a patient ’s competence and confidence in managing their chronic condition, which is assumed to lead to an improved quality of life (QoL). We analyzed the relationship between the Epilepsy Self-Management Scale (ESMS) responses and the Quality of Life in Epilepsy (QOLIE-31) scores. Baseline questionnaires f rom HOBSCOTCH, a self-management program for cognitive problems, were administered in four New England epilepsy centers on adults (n = 100) with epilepsy and subjective memory complaints. There was no correlation between overall self-management score...
Source: Journal of Neurology - Category: Neurology Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
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