Evidence of Coronavirus (CoV) Pathogenesis and Emerging Pathogen SARS-CoV-2 in the Nervous System: A Review on Neurological Impairments and Manifestations
AbstractThe coronavirus disease 2019 (COVID-19) pandemic is an issue of global significance that has taken the lives of many across the world. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for its pathogenesis. The pulmonary manifestations of COVID-19 have been well described in the literature. Initially, it was thought to be limited to the respiratory system; however, we now recognize that COVID-19 also affects several other organs, including the nervous system. Two similar human coronaviruses (CoV) that cause severe acute respiratory syndrome (SARS-CoV-1) and Middle East respiratory syndrome (MERS-CoV) are also known to cause disease in the nervous system. The neurological manifestations of SARS-CoV-2 infection are growing rapidly, as evidenced by several reports. There are several mechanisms responsible for such manifestations in the nervous system. For instance, post-infectious immune-mediated processes, direct virus infection of the central nervous system (CNS), and virus-induced hyperinflammatory and hypercoagulable states are commonly involved. Guillain-Barr é syndrome (GBS) and its variants, dysfunction of taste and smell, and muscle injury are numerous examples of COVID-19 PNS (peripheral nervous system) disease. Likewise, hemorrhagic and ischemic stroke, encephalitis, meningitis, encephalopathy acute disseminated encephalomyelitis, endothelialitis, and venous sinus thrombosis are some instances of COVID-19 CNS dise...
Prevalences, nuances of presentation, and likely clinical course of myocarditis after use of some vaccines against SARS-CoV-2 are in sharper view after additions to the literature this week.Medscape Medical News
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Mariana Rodriguez-Hakim, Linard R äz, Jan Vermant Some contagious diseases, such as COVID-19, spread through the transmission of aerosols and droplets. Aerosol and droplet formation occurs inside and outside of the respiratory tract, the latter being observed... The content of this RSS Feed (c) The Royal Society of Chemistry
Abbott Laboratories has distributed more than 1.4 billion Covid-19 tests globally since the start of the pandemic, including around 300 million in the fourth quarter of 2021. Its global Covid-19 testing-related sales were $2.3 billion in the fourth quarter and $7.7 billion for the full year in 2021.
A deep molecular dive into COVID-19 patients found that the presence of autoantibodies in peripheral blood at initial diagnosis was the chief of four risk factors predicting if a patient would experience long COVID.Medscape Medical News
NIH-sponsored study assessed dose in adults fully vaccinated with any EUA or approved COVID-19 vaccine
ConclusionsThe risk of perioperative thrombosis in UC patients was considered similar to that in CRC, so active thromboprophylaxis should be administered to UC patients while paying attention to bleeding.Trial registrationThis study was registered with the Japanese Clinical Trials Registry as UMIN000042004 (http://www.umin.ac.jp/ctr/index.htm).
ConclusionsDespite advances in perioperative care, VTE after esophagectomy still represents a source of morbidity for about 4% of patients. Low molecular weight heparin is suggested as the routine standard prophylactic regimen after esophageal cancer surgery.
AbstractPurposesThe spread of coronavirus disease 2019 (COVID-19) has affected socioeconomic and healthcare systems in many countries. Accordingly, many individuals may have canceled their annual health-check programs, including esophagogastroduodenoscopy, which would have resulted in lower numbers of newly diagnosed patients with gastric cancer in comparison to other times.MethodsQuestionnaires were distributed to 62 hospitals every week from May 2020 to August 2020 (total 744) through mailing lists of the Stomach Cancer Study Group of the Japan Clinical Oncology Group. The number of patients with gastric cancer and hospi...
Hi everyone. I'm new to SDN so please be nice A little background: I'm a first year MSW student focusing on psychodynamic clinical social work. During the pandemic I realized that I wanted to go back to school to become a psychotherapist and began the process of looking into gradate school options. Truthfully, I really wanted to do my doctorate in clinical psychology but as this was a slightly later in life realization (I'm in my late 20s) and wasn't a psych undergrad with any... Read more
Despite declining national numbers, Americans should not lose sight of the ongoing public health crisis as hospitals remain overwhelmed with COVID-19 patients, many of whom are unvaccinated.WebMD Health News