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Total 209 results found since Jan 2013.

Ischemic Stroke in Children and Young Adults With Congenital Heart Disease Congenital Heart Disease
Conclusions The risk of developing ischemic stroke was almost 11 times higher in young patients with CHD than in the general population, although absolute risk is low. Cardiovascular comorbidities were strongly associated with the development of ischemic stroke in young CHD patients.
Source: JAHA:Journal of the American Heart Association - February 23, 2016 Category: Cardiology Authors: Mandalenakis, Z., Rosengren, A., Lappas, G., Eriksson, P., Hansson, P.-O., Dellborg, M. Tags: Epidemiology, Congenital Heart Disease, Ischemic Stroke Source Type: research

Causes of ischemic stroke in young adults versus non-young adults: A multicenter hospital-based observational study
CONCLUSIONS: Certain embolic sources and uncommon causes may be etiologically important causes of ischemic stroke in young adults. However, the contribution of conventional vascular risk factors and lifestyle-related risk factors is not negligible with advancing age, even in young adults.PMID:35830430 | DOI:10.1371/journal.pone.0268481
Source: Atherosclerosis - July 13, 2022 Category: Cardiology Authors: Yuichiro Ohya Ryu Matsuo Noriko Sato Fumi Irie Kuniyuki Nakamura Yoshinobu Wakisaka Tetsuro Ago Masahiro Kamouchi Takanari Kitazono Investigators for Fukuoka Stroke Registry Source Type: research

Toward a better understanding of PFO and stroke risk
A patent foramen ovale (PFO) is a remnant of the fetal circulation and may be found in approximately 25% of adults.1 Multiple case-control studies have demonstrated an association between PFO and cryptogenic ischemic stroke, particularly in younger patients.2 The mechanism for the association is presumed to be venous thromboembolism through the PFO and into the cerebral circulation (i.e., paradoxical embolization).3 Randomized studies of percutaneous PFO closure devices for secondary stroke prevention have been in progress for years with slow enrollment because of off-label use of atrial septal defect closure devices.4,5 T...
Source: Neurology - August 12, 2013 Category: Neurology Authors: Messe, S. R., Kernan, W. N. Tags: Stroke in young adults, Stroke prevention, Prognosis, Embolism EDITORIALS Source Type: research

Recent Nationwide Trends in Transcranial Doppler Utilization During Acute Ischemic Stroke Hospitalizations (P4.296)
Conclusions:Over the last decade there has been a slight but steady decrease in the use of TCD during AIS hospitalizations in the US. Future studies should examine the cost-utility of TCD, especially with the advent of endovascular stroke treatment systems.Disclosure: Dr. Liu has nothing to disclose. Dr. Lunagariya has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Ovbiagele has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Liu, Y., Lunagariya, A., Patel, U., Patel, A., Feng, W., Ovbiagele, B. Tags: In-Hospital Stroke Care Source Type: research

Percutaneous atrial shunt closure and the risk of recurrent ischemic stroke: A register-based, nationwide cohort study
Patent foramen ovale may cause paradoxical emboli1. Cryptogenic ischemic cerebrovascular events (stroke or transient ischemic attack) (CVE) accounts for about 25% of ischemic strokes.2,3 Transcatheter closure of atrial shunts, including atrial septal defects (ASD) and patent foramen ovale (PFO), was introduced in 1996.4-6 Initially,randomized studies failed7-9 but more recent randomized studies have shown superiority of interventional treatment, with 68 % reduction of recurrent stroke after transcatheter closure of PFO compared with medical treatment in patients with cryptogenic CVE.
Source: Journal of Stroke and Cerebrovascular Diseases - March 23, 2023 Category: Neurology Authors: Alexia Karagianni, Zacharias Mandalenakis, Savvas Papadopoulos, Mikael Dellborg, Peter Eriksson Source Type: research

Cardiovascular diseases in patients 65 years and younger with non-cardiogenic stroke.
CONCLUSIONS: Aetiologically heterogeneous stroke and cardiogenic stroke are the most commonly observed among young stroke patients. Cardiomyopathy and atrial fibrillation are the most common sources of cerebral embolism in young patients with cardiogenic stroke. Nearly 1/5 of patients with a non-cardiogenic stroke have congenital or acquired structural changes in the heart. PMID: 27279848 [PubMed]
Source: Archives of Medical Science - June 10, 2016 Category: Journals (General) Tags: Arch Med Sci Source Type: research

Device used to close small hole in heart may protect against recurrent stroke
A device used to close a small hole in the heart may benefit certain stroke patients by providing an extra layer of protection for those facing years of ongoing stroke risk, according to the results of a large clinical trial led by UCLA researchers.“It is a major new treatment option for some people,” said Dr. Jeffrey Saver, director of theUCLA Comprehensive Stroke Center and lead author of the study. However, he added, “Using the device is going to have to be a considered clinical decision between the doctor and the patient about who’s the right person to get it.”Thefindings appear in the Sept. 14 New England Jo...
Source: UCLA Newsroom: Health Sciences - September 14, 2017 Category: Universities & Medical Training Source Type: news

Gore Takes on Abbott with New PFO Stroke Indication
W.L. Gore & Associates has received FDA approval to expand the indication of the Gore Cardioform Septal Occluder to reduce the risk of recurrent ischemic stroke in patients. The device treats patients through the closure of patent foramen ovale (PFO). Cardioform’s previous indication was for the closure of atrial septal defects that are up to 17mm in size. Gore’s Structural Heart Leader, Jake Goble said Cardioform has the potential to redefine stroke prevention. Goble began working for Gore in 2007. It was around that time the company began to explore the possibility of having the Cardioform focus on stroke prevent...
Source: MDDI - April 3, 2018 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Source Type: news

Airplane stroke syndrome
We describe the patient, stroke, and flight characteristics. Over the study period, 131 million passengers arrived at Melbourne airport. Our centre admitted 5727 stroke patients, of whom 42 (0.73%) had flight-related strokes. Flight-related stroke patients were younger (median age 65 versus 73, p<0.001), had similar stroke severity, and received intravenous thrombolysis more often than non-flight-related stroke patients. Seven patients had flight-related intracerebral haemorrhage. The aetiology of the ischaemic strokes was cardioembolic in 14/35 (40%), including seven patients with confirmed PFO, one with atrial sep...
Source: Journal of Clinical Neuroscience - February 20, 2016 Category: Neuroscience Source Type: research

ESOC 2017 Roundup: Gore touts lowered ischemic stroke, new brain infarcts in PFO Occluder test
W.L. Gore & Associates yesterday released results from the Reduce study of its Cardioform Septal Occluder devices used to close patent foramen ovale, touting a reduction in recurrent ischemic strokes and new brain infarcts. The Gore Cardioform Septal Occluder is designed to be inserted via catheter and is currently cleared by the FDA for closure of atrial septal defects. “It is of the utmost importance to us to be transparent and share clinical data as quickly as possible. We completed our two-year primary endpoint follow-up with patients in March and have worked diligently to release these important data to the ...
Source: Mass Device - May 17, 2017 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Catheters Clinical Trials Stryker W.L. Gore & Associates Source Type: news

Does Atrial Septal Defect Increase the Risk of Stroke Following Total Hip and Knee Arthroplasty?
CONCLUSIONS: Patients with ASD undergoing THA and TKA are predisposed to stroke in the postoperative period. Orthopaedic surgeons indicating patients for surgery and internists performing preoperative medical clearance should be aware of these risks and discuss them prior to surgery. The efficacy of pharmacological and surgical measures to reduce postoperative stroke within this patient population should be topics of future investigation. PMID: 29310146 [PubMed - as supplied by publisher]
Source: Surgical Technology International - January 9, 2018 Category: Surgery Tags: Surg Technol Int Source Type: research

Atrial fibrillation and stroke in adult patients with atrial septal defect and the long-term effect of closure
Conclusions Patients with ASD had a higher risk of first-time AF after closure than the comparison cohort. There was no effect of closure on the use of AF-related medicine in patients with prevalent AF.
Source: Heart - April 9, 2015 Category: Cardiology Authors: Nyboe, C., Olsen, M. S., Nielsen-Kudsk, J. E., Hjortdal, V. E. Tags: Congenital heart disease in adult patients, Congenital heart disease, Drugs: cardiovascular system, Epidemiology Source Type: research

Risk of Recurrent Neurologic Stroke or Transient Ischemic Attack in Patients with Cryptogenic Stroke and Intrapulmonary Shunt
ConclusionsPatients with IPS and cryptogenic stroke or TIA did not have a higher recurrence of ischemic cerebral events. Warfarin was significantly higher at follow‐up in the IPS compared to the non‐IPS group, which may explain these findings. A study randomizing patients with IPS and cryptogenic stroke or TIA to warfarin or no warfarin would be of great interest.
Source: Echocardiography - July 22, 2015 Category: Cardiology Authors: Rahul S. Sinha, Zeeshan Hussain, Nirmanmoh Bhatia, Marcus F. Stoddard Tags: Original Investigation Source Type: research

Ischemic Stroke Occurring During Intercourse in Young Women on Oral Contraceptives
We present 2 cases of young women taking oral contraceptives, each presenting with an ischemic stroke. Transthoracic echocardiography revealed a patent foramen ovale in one patient and an atrial septal defect in the other. The most likely cause of stroke in both patients is embolic. Despite conflicting evidence, young patients presenting with ischemic stroke and found to have a patent foramen ovale or atrial septal defect should be considered for possible device-based closure.
Source: The American Journal of Cardiology - May 19, 2014 Category: Cardiology Authors: P. Elliott Miller, Lorrel Brown, Paras Khandheria, Jon R. Resar Tags: Case Report Source Type: research