Gore Takes on Abbott with New PFO Stroke Indication

W.L. Gore &Associates has received FDA approval to expand the indication of the Gore Cardioform Septal Occluder to reduce the risk of recurrent ischemic stroke in patients. The device treats patients through the closure of patent foramen ovale (PFO). Cardioform’s previous indication was for the closure of atrial septal defects that are up to 17mm in size. Gore’s Structural Heart Leader, Jake Goble said Cardioform has the potential to redefine stroke prevention. Goble began working for Gore in 2007. It was around that time the company began to explore the possibility of having the Cardioform focus on stroke prevention. “One of the things we noticed in the literature early on was the connection between PFO and stroke reduction,” Goble, told MD+DI. "We thought this would be ideal for applying into this space of PFO closure.” Here’s the premise behind the device. In a portion of patients there is a conduit between the right and left side of the heart that doesn’t close after birth. In a subset of these patients there could be clots that could form and break free. The clots could pass from the right to  left side of the heart. These clots aren’t necessarily filtered by the body. The unfiltered clots have an open highway to go anywhere on the arterial side and could potentially end up affecting the blood vessels of the brain causing a stroke. “Our device is designed to close that door betwe...
Source: MDDI - Category: Medical Devices Authors: Tags: Cardiovascular Source Type: news

Related Links:

CONCLUSION: The results support the validity of a 4-factor structure of the LSEQ with 9-items with adequate internal consistency and divergent validity. PMID: 32601644 [PubMed - in process]
Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
CONCLUSION: A clinical assessment of female patients with FM requires a multidisciplinary approach, and patients with excessive daytime sleepiness in particular are recommended to undergo polysomnography. The authors believe that the early detection and treatment of accompanying OSA will contribute not only to the quality of life, but also to the survival of patients with FM. PMID: 32601643 [PubMed - in process]
Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
I'm still waiting on my biology quiz scores to make a final decision, but I am taking summer biology for the sole reason of being premed. However, I have realized that I am likely not doing very well in the class (or at least not as well as I would like) and that it is taking a serious toll on my mental health and sleep schedule (possibly because I am not studying very efficiently or consistently, or because I am just **** at biology). Heck, I took biology honors at the high school level in... Seeking Advice on How To Cope with Dropping Pre-Med
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pre-Medical - MD Source Type: forums
DEMENTIA has no cure but research suggests the choices you make in life may influence your risk of brain decline later on. To that end, certain dietary items have been shown to increase your risk of Alzheimer's disease.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
Authors: Matsushita S, Wong B, Kanumalla R, Goldstein L Abstract Dysmenorrhea, or painful menstruation, is a common cause of acute pelvic pain that affects approximately two-thirds of women who are postmenarchal in the United States. Dysmenorrhea pain is frequently severe enough to disrupt daily activities and often accompanied by other symptoms, such as diarrhea, nausea, vomiting, headache, and dizziness. Primary dysmenorrhea is likely due to an excess of prostaglandins and is traditionally treated with nonsteroidal anti-inflammatory drugs and hormonal therapy. Secondary dysmenorrhea can have multiple origins and ...
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research
We report the case of a 22 year-old male with a clinical picture of 4 months onset of headaches, deafness, and a decrease of vision in the left eye. His mother mentioned he also had changes in behaviour and mood. The magnetic resonance scan of the brain showed multiple hyper-intense lesions in the knee of the corpus callosum. The hearing test reported a neurosensory deafness. In the ophthalmoscopy, a retinal infarction was observed in the nerve fibre layer in the left eye, which was confirmed using optical coherence tomography. The fluorescein angiography showed multiple foci of hyperfluorescence of the arteriole walls, ar...
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
The authors summarize the most important anatomic and physiologic substrates of Fontan circulation. Common anatomic substrates include hypoplastic left heart syndrome, tricuspid atresia, double inlet left ventricle, and unbalanced atrioventricular septal defects. After the Fontan operation exercise capacity is limited and the key hemodynamic drivers is limited preload due to a relatively fixed pulmonary vascular resistance. The authors provide contemporary data on survival, morbidity, and need for reintervention. Operative morality is now expected to be less than 1% and 30 year survival approximately 89%. The authors delin...
Source: Cardiology Clinics - Category: Cardiology Authors: Source Type: research
Authors: Biniwale N, Kibe R, Biniwale A Abstract Neuro-Behcet's disease (NBD) is a rare neurological manifestation of the systemic small vessel vasculitis called Behcet's disease. It can present in various ways with predilection for the brain stem, thalamo- hypothalamic regions, cerebellum and basal ganglia. In this case, we describe a case of young stroke that was later attributed to NBD. PMID: 32602687 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: The varied spectra of COVID-19 presentation included fever, cough, shortness of breath, sore throat etc. Diabetes mellitus, hypertension, COPD/K-Chest and CAD were found as major comorbid conditions. Symptomatic presentation of COVID-19 was observed to be higher in patients with co morbid disease, especially if multiple. HRCT chest in COVID-19 patients had a major diagnostic and prognostic importance as positive CT findings were more prominent in symptomatic patients and co-morbid patients. Clinical symptoms of patients directly correlated with CT severity index. CT imaging was found to be useful in predicting ...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
More News: Atrial Septal Defect | Brain | Cardiology | Cardiovascular | Conferences | Dementia | Headache | Heart | Hole in the Heart | Ischemic Stroke | Migraine | Neurology | Patent Foramen Ovale | Sleep Apnea | Sleep Disorders | Sleep Medicine | Stroke | Study