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Specialty: General Medicine
Condition: Pain

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Total 390 results found since Jan 2013.

A simple risk score in acute ST-elevation myocardial infarction: Modified ACEF(age, creatinine, and ejection fraction) score.
CONCLUSION: The modified ACEF score is a predictor of cardiac mortality and morbidity during 1-year follow-up. PMID: 28081310 [PubMed - in process]
Source: Turkish Journal of Medical Sciences - January 14, 2017 Category: Journals (General) Tags: Turk J Med Sci Source Type: research

Vitamin D supplementation for sickle cell disease.
CONCLUSIONS: We included only one low-quality clinical study which had a high risk of bias with regards to incomplete outcome data. Therefore, we consider that the evidence is not of sufficient quality to guide clinical practice. Until further evidence becomes available, clinicians should consider the relevant existing guidelines for vitamin D supplementation (e.g. the Endocrine Society Clinical Practice Guidelines) and dietary reference intakes for calcium and vitamin D (e.g. from the USA Institute of Medicine). Evidence of vitamin D supplementation in sickle cell disease from high quality studies is needed. Well-designed...
Source: Cochrane Database of Systematic Reviews - January 19, 2017 Category: Journals (General) Authors: Soe HH, Abas AB, Than NN, Ni H, Singh J, Said AR, Osunkwo I Tags: Cochrane Database Syst Rev Source Type: research

Wunderlich Syndrome
A 55-year-old man presented to the Emergency Department with severe abdominal pain for 1 day. He had a history of hypertension, diabetes mellitus, and ischemic stroke. The pain was severe, sharp, and constant, in his left flank; it woke him up from sleep and radiated to the mid back. On physical examination, his vital signs were stable and he had tenderness over the left flank. However, he developed hypotension, with mean arterial pressures dropping to 55  mm Hg and lactic acidosis requiring aggressive volume resuscitation.
Source: The American Journal of Medicine - January 30, 2017 Category: Journals (General) Authors: Aron Simkins, Abhishek Maiti, Sujith V. Cherian Tags: Clinical communication to the editor Source Type: research

Double the Trouble: Acute Coronary Syndrome and Ischemic Stroke in Polycythemia Vera
Vague symptoms turned out to be life-threatening conditions. A 50 year-old man with a history of polycythemia vera, presented to hospital with epigastric discomfort and clumsiness of the right hand for 5 days. Polycythemia vera was diagnosed 1 year prior with good control of hematocrit by intermittent phlebotomy. He did not have any other medical history, and was not taking any medications. He denied chest pain, shortness of breath, nausea, headache, vision change, or speech difficulty.
Source: The American Journal of Medicine - March 12, 2017 Category: Journals (General) Authors: Hitomi Hosoya, Jeffrey J. Levine, David H. Henry, Sheldon Goldberg Tags: Diagnostic Dilemma Source Type: research

Retroauricular pain caused by Eagle syndrome: A rare presentation due to compression by styloid process elongation
We present a rare case of Eagle syndrome (documented by computed tomography) with good response to clinical treatment.Resumo A s índrome de Eagle é uma condição rara na qual ocorre dor retroauricular (usualmente é o principal sintoma) associada a disfagia, cefaleia, cervicalgia durante a rotação da cabeça e, mais raramente, a AVC. Isso ocorre por conta do alongamento do processo estiloide e, às vezes, há também cal cificação do ligamento estiloide. Essas estruturas podem comprimir nervos e artérias causando os sintomas citados. O tratamento pode ser conservador com moduladores da dor, como pregabalina, ou com...
Source: Revista da Associacao Medica Brasileira - May 2, 2017 Category: Journals (General) Source Type: research

Clinical Profile of Hypertensive Emergencies in an Intensive Care Unit.
CONCLUSIONS: most common presenting complaint in patients was breathlessness seen in 17 patients (34%), followed by neurological deficit in 14 patients (28%). Thirteen patients (26%) had complaints of headache, whereas 12 (24%) patients complained of chest pain on admission. Other symptoms included vomiting, giddiness, psychomotor agitation, and decreased urine output. Out of a total of 4076 admissions during the study period in the intensive care unit we had 50 cases of hypertensive emergencies with prevalence of 1.22% in our intensive care unit. Most common organ involvement was the retina followed by cardiovascular syst...
Source: Journal of the Association of Physicians of India - June 11, 2017 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Celecoxib for rheumatoid arthritis.
CONCLUSIONS: Celecoxib may improve clinical symptoms, alleviate pain and contribute to little or no difference in physical function compared with placebo. Celecoxib was associated with fewer numbers of participant withdrawals. Results for incidence of gastroduodenal ulcers (≥ 3 mm) and short-term serious adverse events were uncertain; however, there were few reported events for either.Celecoxib may slightly improve clinical symptoms compared with tNSAIDs. Results for reduced pain and improved physical function were uncertain. Particpants taking celecoxib had lower incidence of gastroduodenal ulcers (≥ 3 mm) and there w...
Source: Cochrane Database of Systematic Reviews - June 9, 2017 Category: General Medicine Authors: Fidahic M, Jelicic Kadic A, Radic M, Puljak L Tags: Cochrane Database Syst Rev Source Type: research

Periprosthetic joint infection caused by Rhodococcus equi. Case report.
We present the first case of periprosthetic joint infection caused by Rhodococcus equi. An 88-year-old male patient was referred to our clinic with a history of fever and right hip pain. The patient had multiple hip surgeries including total joint arthroplasty and revision for aseptic loosening on the right side. He was immunocompetent, but his additional medical history was remarkable for diabetes mellitus, diabetic nephropathy and stroke with hemiplegia resulting in immobilization. Radiography showed stable components, joint aspirate yielded Rhodococcus equi. Irrigation and debridement was proposed, but the patient refus...
Source: Orvosi Hetilap - July 1, 2017 Category: General Medicine Authors: Sallai I, Péterfy N, Sanatkhani M, Bejek Z, Antal I, Prinz G, Kristóf K, Skaliczki G Tags: Orv Hetil Source Type: research

A combination of levobupivacaine and lidocaine for paravertebral block in breast cancer patients undergoing quadrantectomy causes greater hemodynamic oscillations than levobupivacaine alone.
CONCLUSION: The use of 0.5% levobupivacaine in comparison with 0.5% levobupivacaine with 2% lidocaine solution for PVB had a longer time-to-block onset, but it also reduced hemodynamic disturbances and prolonged the analgesic effect. PMID: 28857520 [PubMed - in process]
Source: Croatian Medical Journal - August 31, 2017 Category: General Medicine Authors: Župčić M, Graf Župčić S, Duzel V, Šimurina T, Šakić L, Fudurić J, Peršec J, Milošević M, Stanec Z, Korušić A, Barišin S Tags: Croat Med J Source Type: research

Extracranial Cervical Artery Dissections.
Abstract Cervical artery dissections (CeAD) include both internal carotid and vertebral artery dissections. They are rare but important causes of stroke, especially in younger patients. CeAD should be considered in patients with strokelike symptoms, a new-onset headache and/or neck pain, and/or other risk factors. Early imaging with computed tomography (CT) or magnetic resonance imaging (MRI) is key to making the diagnosis. Treatment may vary depending on the extent of the dissection, timing of the dissection, and other comorbidities. The overall prognosis is good, but does depend on the initial severity of sympto...
Source: The Medical Clinics of North America - October 12, 2017 Category: General Medicine Authors: Robertson JJ, Koyfman A Tags: Emerg Med Clin North Am Source Type: research

A case of refractary epilepsy and related pain due to dysmenorrhea solved with loading dose of lacosamide: clinical and neurophysiological correlates.
Abstract  In most cases, the etiology of epilepsy is unknown, although some individuals may develop epilepsy as a result of certain brain injuries, following a stroke, a brain tumor or because of drugs and alcohol. Even some rare genetic mutations may be related to the onset of the condition. Seizures are the result of excessive and abnormal activity of neurons in the cerebral cortex. In this case report we show a clinical case of refractory epilepsy due to pain related to uncontrolled dysmenorrhea. The patient, 43 yrs old, had a history of epilepsy of 20 years and ovarian cancer. She was treated with lamotrigine...
Source: Acta Bio-Medica : Atenei Parmensis - October 23, 2017 Category: General Medicine Authors: Marchitto N, Ceratti U, Dalmaso S, Raimondi G Tags: Acta Biomed Source Type: research

Treatment of dizziness: an interdisciplinary update.
Abstract This review provides an update on interdisciplinary treatment for dizziness. Dizziness can have various causes and the treatment offered should depend on the cause. After reading this article, the clinician will have an overview of current treatment recommendations. Recommendations are made for the most prevalent causes of dizziness including acute and chronic vestibular syndromes, vestibular neuritis, benign paroxysmal positional vertigo, endolymphatic hydrops and Menière's disease, vestibular paroxysmia and vestibular migraine, cardiac causes, transient ischaemic attacks and strokes, episodic ataxia ty...
Source: Swiss Medical Weekly - December 28, 2017 Category: General Medicine Authors: Spiegel R, Rust H, Baumann T, Friedrich H, Sutter R, Göldlin M, Rosin C, Müri R, Mantokoudis G, Bingisser R, Strupp M, Kalla R Tags: Swiss Med Wkly Source Type: research

Comment Antithrombotic therapy in peripheral artery disease
Peripheral artery disease is a systemic atherothrombotic disease in which plaque builds up in the arteries that carry blood to the limbs. If severe enough, impaired blood flow can cause critical limb ischaemia, which presents as resting pain, ulceration, or gangrene, and might require a limb amputation in the most extreme cases.1 People with peripheral artery disease often have plaque in other arterial beds, and thus are at increased risk for myocardial infarction, ischaemic stroke, and cardiovascular death.
Source: LANCET - November 10, 2017 Category: General Medicine Authors: Jeffrey S Berger Tags: Comment Source Type: research

The burden of disease in Spain: Results from the Global Burden of Disease 2016.
CONCLUSION: Low back and neck pain was the most important contributor of disability in Spain in 2016. There has seen a remarkable increase in the burden due to Alzheimer disease and other dementias. Tobacco remains the most important health issue to address in Spain. PMID: 30037695 [PubMed - as supplied by publisher]
Source: Medicina Clinica - July 26, 2018 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Alcohol and Neurology.
Abstract The nervous system is a particular target tissue for alcohol due to desired effects and numerous acute and chronic consequences. Acute consequences are due to episodes of overconsumption, withdrawal syndromes, or decompensation of nutritional deficiencies. Chronic consequences are dominated by sleep disorders, chronic pain and cognitive-behavioral disorders, stroke, and impairments of balance, peripheral nerves and muscles, resulting from direct toxicity and/or nutritional deficiencies. There is a bidirectional relationship requiring seeking: alcohol use as a causal or aggravating factor in any neurologic...
Source: Presse Medicale - July 23, 2018 Category: General Medicine Authors: Dematteis M, Pennel L Tags: Presse Med Source Type: research