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Condition: Hypertension
Procedure: MRI Scan

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Total 404 results found since Jan 2013.

Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study Clinical Sciences
Conclusions— Among young healthy adults, higher aortic stiffness was associated with measures of reduced white matter and GM integrity in areas implicated in cognitive decline and Alzheimer’s disease. Greater aortic stiffness may result in subclinical vascular brain injury at ages much younger than previously described.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Maillard, P., Mitchell, G. F., Himali, J. J., Beiser, A., Tsao, C. W., Pase, M. P., Satizabal, C. L., Vasan, R. S., Seshadri, S., DeCarli, C. Tags: Aging, High Blood Pressure, Magnetic Resonance Imaging (MRI) Clinical Sciences Source Type: research

Microalbuminuria and the Combination of MRI Markers of Cerebral Small Vessel Disease
Conclusions: A significant proportion of stroke-free hypertensives present at least one imaging marker of CSVD. UACR but not creatinine-based glomerular filtration rate is associated with the combination of markers of CSVD.Cerebrovasc Dis 2016;42:66-72
Source: Cerebrovascular Diseases - March 31, 2016 Category: Neurology Source Type: research

Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study Epidemiology
Conclusions Cumulative vascular risk factor exposure may increase the risk of CMB, especially in deep regions. The apparent paradoxical association of carotid intima–media thickness progression with lower risk of CMB may reflect benefits of intensive vascular risk factor treatment among persons with higher cardiovascular risk and deserves further investigation. If replicated, the results may have potential implications for assessment of preventive and therapeutic interventions for subclinical cerebral hemorrhage.
Source: JAHA:Journal of the American Heart Association - March 17, 2016 Category: Cardiology Authors: Romero, J. R., Preis, S. R., Beiser, A., DeCarli, C., D'Agostino, R. B., Wolf, P. A., Vasan, R. S., Polak, J. F., Seshadri, S. Tags: Epidemiology, Magnetic Resonance Imaging (MRI), Ultrasound, Cerebrovascular Disease/Stroke, Atherosclerosis Source Type: research

Balloon Pulmonary Angioplasty Improves Biventricular Functions and Pulmonary Flow in Chronic Thromboembolic Pulmonary Hypertension.
CONCLUSIONS: BPA improves biventricular functions and pulmonary flow in patients with inoperable CTEPH. PMID: 27097557 [PubMed - as supplied by publisher]
Source: Circulation Journal - April 19, 2016 Category: Cardiology Authors: Sato H, Ota H, Sugimura K, Aoki T, Tatebe S, Miura M, Yamamoto S, Yaoita N, Suzuki H, Satoh K, Takase K, Shimokawa H Tags: Circ J Source Type: research

Cerebral Microbleeds, Cognition and Therapeutic Implications
A recent major clinical advance in magnetic resonance imaging (MRI) of the brain is the development of paramagnetic-sensitive sequences such as T2-weighted gradient-recalled echo and susceptibility-weighted images for the detection of cerebral microbleeds (CMBs). On brain MRI, CMBs are small (≤5 to 10 mm in diameter), round, dark-signaled lesions that consist of extravasation of blood components through fragile microvascular walls that neuropathologically represent hemosiderin-laden macrophages. Magnetic resonance imaging–detected CMBs are common in elderly individuals, coexist with ischemic stroke and intracerebral he...
Source: JAMA Neurology - June 6, 2016 Category: Neurology Source Type: research

New insights into coupling and uncoupling of cerebral blood flow and metabolism in the brain.
Abstract The brain has high metabolic and energy needs and requires continuous cerebral blood flow (CBF), which is facilitated by a tight coupling between neuronal activity, CBF, and metabolism. Upon neuronal activation, there is an increase in energy demand, which is then met by a hemodynamic response that increases CBF. Such regional CBF increase in response to neuronal activation is observed using neuroimaging techniques such as functional magnetic resonance imaging and positron emission tomography. The mechanisms and mediators (eg, nitric oxide, astrocytes, and ion channels) that regulate CBF-metabolism coupli...
Source: Croatian Medical Journal - June 29, 2016 Category: Journals (General) Authors: Venkat P, Chopp M, Chen J Tags: Croat Med J Source Type: research

Early neurological and cognitive impairments in subclinical cerebrovascular disease
Conclusions: Our results have contributed to the hypothesis that it is possible to identify, by noninvasive methods, subjects at age at risk who have mild degree of cognitive impairment and to establish the significant relationship of this impairment with existing CVRFs, nonspecific symptoms and subclinical abnormal brain Doppler/MRI findings. We created a combined neuropsychological predictor that was able to clearly distinguish between the presence and absence of abnormal Doppler/MRI findings. This pilot prognostic model showed a relatively high accuracy of >80%; therefore, the predictors may serve as bioma...
Source: Neurology India - July 4, 2016 Category: Neurology Authors: Penka A AtanassovaRadka I MassaldjievaBorislav D DimitrovAleksandar S AleksandrovMaria A SemerdjievaSilvia B TsvetkovaNedka T ChalakovaKostadin A Chompalov Source Type: research

Scimitar Syndrome Repair in Adults: Intermediate-Term Results Using an Extracardiac Conduit
Conclusions Correction of scimitar syndrome with an extracardiac conduit can be easily and safely performed in adults, with excellent intermediate-term durability, without graft thrombi or stenosis. This technique avoids deep hypothermic circulatory arrest when the SV is short or enters the IVC in an unusually caudad location.
Source: The Annals of Thoracic Surgery - July 15, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Scimitar Syndrome Repair in Adults: Intermediate-Term Results Using an Extracardiac Conduit.
CONCLUSIONS: Correction of scimitar syndrome with an extracardiac conduit can be easily and safely performed in adults, with excellent intermediate-term durability, without graft thrombi or stenosis. This technique avoids deep hypothermic circulatory arrest when the SV is short or enters the IVC in an unusually caudad location. PMID: 27424466 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 13, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Guerra NC, Pernot M, Nesseris G, Al-Yamani M, Roques X, Thambo JB, Kreitmann B, Roubertie F Tags: Ann Thorac Surg Source Type: research

Evaluation of the pharmacoDYNAMIC effects of riociguat in subjects with pulmonary hypertension and heart failure with preserved ejection fraction : Study protocol for a  randomized controlled trial.
Evaluation of the pharmacoDYNAMIC effects of riociguat in subjects with pulmonary hypertension and heart failure with preserved ejection fraction : Study protocol for a randomized controlled trial. Wien Klin Wochenschr. 2016 Sep 2; Authors: Mascherbauer J, Grünig E, Halank M, Hohenforst-Schmidt W, Kammerlander AA, Pretsch I, Steringer-Mascherbauer R, Ulrich S, Lang IM, Wargenau M, Frey R, Bonderman D Abstract BACKGROUND: The presence of pulmonary hypertension (PH) severely aggravates the clinical course of heart failure with preserved ejection fraction (HFPEF) resulting in substantial morbidity and ...
Source: Wiener Klinische Wochenschrift - September 1, 2016 Category: Journals (General) Authors: Mascherbauer J, Grünig E, Halank M, Hohenforst-Schmidt W, Kammerlander AA, Pretsch I, Steringer-Mascherbauer R, Ulrich S, Lang IM, Wargenau M, Frey R, Bonderman D Tags: Wien Klin Wochenschr Source Type: research

Cerebral venous thrombosis.
Abstract Cerebral venous thrombosis (CVT) has an incidence of 1.32/100,000/years in high-income countries, and higher in middle- and low-income countries. CVT is more frequent in infants and children young adults and females, especially during pregnancy/puerperium. CVT are now being diagnosed with increasing frequency because of the increased awareness and higher use of magnetic resonance imaging (MR) for investigating patients with acute and subacute headaches and new onset seizures. CVT rarely present as a stroke syndrome. Their most frequent presentations are isolated headache, intracranial hypertension syndrom...
Source: Presse Medicale - November 1, 2016 Category: Journals (General) Authors: Ferro JM, Canhão P, Aguiar de Sousa D Tags: Presse Med Source Type: research

A Case of Hypertensive Encephalopathy with Enlarged Optic Nerve Sheath Measured by Transorbital Sonography
This case report describes our experience in using transorbital sonography to evaluate pathological changes in the central nervous system in hypertensive encephalopathy. A 49-year-old man with nausea, headache, and mild confusion was diagnosed with hypertensive encephalopathy by brain magnetic resonance imaging (MRI), which revealed vasogenic edema in the bilateral thalamus and the brain stem. Lumbar puncture showed no severe intracranial hypertension. Transorbital sonography showed an increase in the optic nerve sheath diameter (ONSD).
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2016 Category: Neurology Authors: Takaya Kitano, Tomohisa Nezu, Tomoya Mukai, Jyunichi Uemura, Yuko Wada, Yoshiki Yagita Tags: Case Studies Source Type: research

Response to treatment assessment in patients with PAH by MRI based computational modelling
Conclusion: The non-invasive proposed metrics have the potential to assess the response to PAH therapy, reducing the RHC interventions at follow-up.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Lungu, A., Hose, R., Capener, D., Kiely, D., Wild, J., Swift, A. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease
Discussion: Advancing age is independently associated with pulmonary arterial compliance in health and disease. In contrast to younger patients, pulmonary arterial compliance does not increase in response to PAH therapy in older patients.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Swift, A., Lungu, A., Capener, D., Hammerton, C., Rothman, A., Lawrie, A., Elliot, C., Condliffe, R., Kiely, D., Wild, J. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Contrast ‐induced encephalopathy following cardiac catheterization
ConclusionsCIE is an important clinical entity to consider in the differential diagnosis of stroke following cardiac catheterization. Given that prognosis is excellent with supportive management only, physicians should be aware of it, and consider it prior to initiating thrombolysis. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - November 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Roberto Spina, Neil Simon, Romesh Markus, David WM Muller, Krishna Kathir Tags: Coronary Artery Disease Source Type: research