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Influence of dietary patterns on the risk of acute myocardial infarction in China population: the INTERHEART China study.
CONCLUSIONS: Unhealthy dietary intake can increase the AMI risk. Improving intake of vegetables, fruits and tofu have the potential to partially prevent the rising epidemic of cardiovascular disease in China. PMID: 23422108 [PubMed - in process]
Source: Chinese Medical Journal - February 1, 2013 Category: Journals (General) Authors: Guo J, Li W, Wang Y, Chen T, Teo K, Liu LS, Yusuf S, INTERHEART China study investigators Tags: Chin Med J (Engl) Source Type: research

Republished: Mainstreaming HIV services for men who have sex with men: the role of general practitioners
Mainstreaming HIV services for men who have sex with men: The role of general practitioners General practitioners (GPs) and other primary care doctors around the world have a strong potential for providing quality HIV prevention, testing and treatment for men who have sex with men, as advocated by the recent WHO guideline.1 As the HIV epidemic becomes more focused on chronic disease care in many parts of the world, a number of primary care issues come to the forefront of clinical HIV service delivery. GPs have advantages in providing HIV services because of their position as trusted, community-based, long-term advocates fo...
Source: Postgraduate Medical Journal - March 12, 2013 Category: Journals (General) Authors: Wong, W. C. W., Kidd, M. R., Tucker, J. D. Tags: Liver disease, Sexual transmitted infections (viral), General practice / family medicine, Immunology (including allergy), Drugs: infectious diseases, HIV/AIDS, Stroke, Hypertension, Communication, Ethics, Legal and forensic medicine Republished editoria Source Type: research

Association of obesity with socio-economic factors and obesity-related chronic diseases in rural southwest China
Conclusions: In order to reduce the obesity epidemic in rural southwest China, effective interventions must address socio-economic factors. Reducing obesity has a profound impact on the reduction of morbidity associated with cardiovascular diseases and diabetes.
Source: Public Health - February 22, 2013 Category: Global & Universal Authors: L. Cai, J. He, Y. Song, K. Zhao, W. Cui Tags: Original Research Source Type: research

Insulin Resistance, Small LDL Particles, and Risk for Atherosclerotic Disease.
Abstract There is a global epidemic of obesity, metabolic syndrome, and diabetes mellitus. Insulin resistance (IR) is etiologic for both metabolic syndrome and diabetes mellitus. IR induces a broad range of toxic systemic effects, including dyslipidemia, hypertension, hyperglycemia, increased production of advanced glycosylation end products, increased inflammatory tone, as well as a prothrombotic and pro-oxidative state. Patients with IR are highly vulnerable to the development of accelerated atherosclerosis as well its clinical sequelae, including coronary artery disease and myocardial infarction, carotid artery...
Source: Current Vascular Pharmacology - April 25, 2013 Category: Drugs & Pharmacology Authors: Toth PP Tags: Curr Vasc Pharmacol Source Type: research

Pharmacotherapy of obesity: clinical treatments and considerations.
Abstract Obesity is a world-wide epidemic associated with significant morbidity and mortality which costs billions of dollars per year. The associated related conditions are many and include heart disease, stroke, type II diabetes mellitus, sleep apnea and certain types of cancer. Given that it is a multifactorial problem, the treatments must also address the numerous causes associated with the development of obesity. The neurohormonal regulation of feeding and energy is a complex system often necessitating modification through more than 1 pathway to achieve weight loss. Therefore, in addition to lifestyle changes...
Source: The American Journal of the Medical Sciences - April 1, 2013 Category: Journals (General) Authors: Holes-Lewis KA, Malcolm R, O'Neil PM Tags: Am J Med Sci Source Type: research

MicroRNAs In Arterial Hypertension.
Abstract Arterial hypertension is an epidemic currently affecting almost a billion people worldwide. The consequences from high blood pressure vary, from peripheral arterial disease and chronic kidney failure to acute myocardial infarction and stroke. MicroRNAs (miRNAs) are small non-coding RNA molecules comprised of 22-26 nucleotides and provide post-transcriptional protein expression regulation. The many biological processes in which they are implicated, such as cell proliferation, apoptosis, metabolism, cell differentiation and morphogenesis confirms the functional significance of miRNAs. It has been found that...
Source: Current Topics in Medicinal Chemistry - May 31, 2013 Category: Chemistry Authors: Synetos A, Toutouzas K, Stathogiannis K, Latsios G, Tsiamis E, Tousoulis D, Stefanadis C Tags: Curr Top Med Chem Source Type: research

If you could propose one idea to help improve health care delivery in the United States, what would it be?
Thumbnail: Tags: conversationsphrma conversationslarry hausnermyrl weinbergchris hansennancy brownContributors: 11621161115911631173Contributions: Read Larry Hausner's bio Despite the rapid development of innovative technologies in the health care field, we have yet to discover a panacea that will easily transform our health care system into one that provides high-quality and cost-effective care.  What we have discovered and come to agree on over the last decade is that our sick care system must be reconfigured to a health care system that emphasizes wellness and prevention.  For that reason, I offer ...
Source: PHRMA - June 24, 2013 Category: Pharmaceuticals Authors: rlowe Source Type: news

Hypertension-related diseases as a common cause of hospital mortality in Tanzania: a 3-year prospective study
Conclusion: NCDs account for half of all deaths, admissions and hospital days at our Tanzanian hospital and hypertension-related diseases were the most common NCD. Hypertension accounted for 34% of NCD deaths and 15% of all deaths. Hypertension was the second most common cause of death overall and the leading cause of death in patients more than 50 years old. More than half of hypertension-related deaths occurred before retirement age. These findings have important implications for public health and medical education in sub-Saharan Africa, wherein hypertension and related diseases have not traditionally been given a high priority.
Source: Journal of Hypertension - August 16, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research

Population-based study of cardiovascular health in Atahualpa, a rural village of coastal Ecuador
The American Heart Association (AHA) recently defined the metrics needed to categorize cardiovascular health (CVH), to implement strategies directed to reduce vascular deaths among US populations . The same could be applied to developing countries, where stroke and cardiovascular diseases will be the next health epidemics due to changes in lifestyle and increased life expectancy . Indeed, the rate of vascular deaths in Latin America is higher than in the developed world; this excess mortality fraction could be related to modifiable factors, including: inadequate access to medical care, increasing obesity and diabetes melli...
Source: International Journal of Cardiology - February 13, 2013 Category: Cardiology Authors: Oscar H. Del Brutto, Milton Santamaría, Elio Ochoa, Ernesto Peñaherrera, Rocío Santibáñez, Freddy Pow-Chon-Long, Mauricio Zambrano, Victor J. Del Brutto Tags: Letters to the Editor Source Type: research

Ceruloplasmin dysfunction: a key factor in the pathophysiology of atrial fibrillation?
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - November 5, 2013 Category: Internal Medicine Authors: Jamie Y Jeremy, Nilima Shukla Tags: Editorial Comment Source Type: research

The effect of continuous positive airway pressure therapy on vascular function in obstructive sleep apnea: how much is enough?
Over the last two decades, obstructive sleep apnea (OSA) has emerged as a considerable public health burden. Due to the ongoing epidemic of obesity, which is strongly linked to OSA, the prevalence of the disease has been steadily rising. According to recent data from the Wisconsin Sleep Cohort, the combination of sleep-disordered breathing as indicated by an apnea–hypopnea index of>5 events per hour and excessive daytime sleepiness occurs in approximately 14% of men and 5% of women between the ages of 30 and 70years . Cardiovascular diseases (CVDs) represent the principal morbidity and mortality in OSA and large-scale ep...
Source: Sleep Medicine - November 8, 2013 Category: Sleep Medicine Authors: Silke Ryan Tags: Editorials Source Type: research

Committee opinion no. 591: challenges for overweight and obese women.
Authors: Abstract Overweight and obesity are epidemic in the United States. Obesity is a risk factor for numerous conditions, including diabetes, hypertension, high cholesterol, stroke, heart disease, certain types of cancer, and arthritis. The prevalence of obesity is high, exceeding 30% in adult women and men. Many women, irrespective of demographic characteristics or income, are vulnerable to becoming overweight or obese because of limited resources for physical activity and healthy food choices, work commitments, and family demands. Clinicians and public health officials should address not only individual beh...
Source: Obstetrics and Gynecology - February 23, 2014 Category: OBGYN Tags: Obstet Gynecol Source Type: research

Obesity: The New Epidemic
Over the past decade, obesity has become recognized as a national health threat and a major public health challenge. Approximately 72.5 million adults in the United States are obese. Obese adults are at increased risk for many serious health conditions, including coronary heart disease, hypertension, stroke, type 2 diabetes, certain types of cancer, and premature death. Adult obesity also is associated with a reduced quality of life, social stigmatization, and discrimination. Diseases associated with obesity are responsible for 27% of the increases in US medical costs. Medical costs associated with obesity have been estima...
Source: The Journal for Nurse Practitioners - March 20, 2014 Category: Nursing Authors: Laurel Halloran Tags: Hot Topics in Primary Care Source Type: research

Comment: Intracerebral hemorrhage incidence declines, but it is still highly fatal
Overall stroke mortality has declined over the last decades—a welcome trend.1 However, recent trends in intracerebral hemorrhage (ICH) incidence are not as clear. On the one hand, there has been increasingly good population control of hypertension; on the other hand, there is increasing use of anticoagulants and antithrombotic drugs, an epidemic of obesity and diabetes, and changing racial and ethnic demographics.
Source: Neurology - June 16, 2014 Category: Neurology Authors: Smith, E. E. Tags: Cohort studies, Incidence studies, Natural history studies (prognosis), Intracerebral hemorrhage ARTICLE Source Type: research

Watch less TV to prevent obesity, says NICE
“Take TV-free days to combat obesity, health experts urge,” The Guardian reports. This is one of a range of new recommendations from National Institute of Health and Care Excellence (NICE) draft guidelines that are designed to help adults and children maintain a healthy weight.Although the headlines have largely focused on TV (as well as other types of screen time, such as smartphones), the recommendations cover a range of health-related behaviours, such as walking to work and avoiding fizzy drinks.This draft guidance is mainly aimed at people in organisations who set up, pay for, or put into practice programmes that ...
Source: NHS News Feed - September 23, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Food/diet Obesity Source Type: news

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