Insomnia: the enemy feeding the literary genius of Franz Kafka
We read the wonderful paper by Iranzo et  al., about Kafka's insomnia [1]. To complete their accurate analysis, we will shortly discuss the complex relationship of Kafka with sleep, as well as insomnia affecting his creativity. (Source: Sleep Medicine)
Source: Sleep Medicine - October 17, 2018 Category: Sleep Medicine Authors: A. Perciaccante, A. Coralli Tags: Letter to the Editor Source Type: research

Response to comment on "A narrative review of interventions for improving sleep and reducing circadian disruption in medical inpatients ”
We thank our colleagues for their interest in our recently published review article [1]. In our narrative review, we discussed how patient characteristics, hospital routines, and hospital environment may all contribute to sleep and circadian disruption in hospitalized patients. In their letter, Mortazavi et al., discussed the use of electronic devices, such as smartphones and e-tablets, as an additional factor that may disrupt inpatients ’ sleep and circadian rhythm [2]. Smartphones and e-tablets emit light in the blue range, and experimental studies have linked the use of blue light emitting devices during evening h...
Source: Sleep Medicine - October 17, 2018 Category: Sleep Medicine Authors: Xiao Tan, Lieve van Egmond, Markku Partinen, Tanja Lange, Christian Benedict Source Type: research

Association between sleep quality and bone mineral density in Chinese women vary by age and menopausal status
This study aimed to examine the association between sleep quality and BMD in Chinese women vary by age groups and menopausal status. (Source: Sleep Medicine)
Source: Sleep Medicine - October 16, 2018 Category: Sleep Medicine Authors: Jie Lin, Lijin Chen, Saili Ni, Yuan Ru, Sunyue Ye, Xiaohua Fu, Da Gan, Jiayu Li, Liang Zhang, Shuang Han, Shankuan Zhu Tags: Original Article Source Type: research

Disease-specific attention impairment in disorders of chronic excessive daytime sleepiness
Patients with chronic excessive daytime sleepiness (EDS) complain of substantial attention deficits. However, their underlying neuronal dysfunction is largely unknown. Previous studies showed similar attention performances in central disorders of hypersomnolence suggesting that EDS-related cognitive impairment is independent of its cause. The aim of the current study was to further explore attentional profiles in disorders of chronic EDS. (Source: Sleep Medicine)
Source: Sleep Medicine - October 15, 2018 Category: Sleep Medicine Authors: Markus Ramm, Matthias Boentert, Nelly Lojewsky, Arsalan Jafarpour, Peter Young, Anna Heidbreder Tags: Original Article Source Type: research

Prothrombotic state in children with obstructive sleep apnea
Increased blood coagulation might be one important mechanism linking obstructive sleep apnea (OSA) with cardiovascular diseases. We tested the association between several hemostatic parameters and sleep breathing-related variables in a representative pediatric population with a clinical suspicion of OSA. (Source: Sleep Medicine)
Source: Sleep Medicine - October 13, 2018 Category: Sleep Medicine Authors: Antonia Barcel ó, Daniel Morell-Garcia, Pilar Sanchís, José Antonio Peña-Zarza, Josep Miquel Bauça, Javier Piérola, Mónica de la Peña, Nuria Toledo-Pons, Paloma Giménez, Caterina Ribot, Alberto Alonso-Fernández Source Type: research

Melatonin receptor 1B −1193T > C polymorphism is associated with diurnal preference and sleep habits
Melatonin modulates the master circadian clock through the activation of G-protein-coupled receptors MT1 and MT2. It is presumed, therefore, that genetic variations in melatonin receptors can affect both sleep and circadian phase. We investigated whether the −1193T>C (rs4753426) polymorphism in the promoter of MT2 receptor gene (MTNR1B) is associated with diurnal preference and sleep habits. This polymorphism was previously associated with sunshine duration, suggesting a role in circadian entrainment. (Source: Sleep Medicine)
Source: Sleep Medicine - October 13, 2018 Category: Sleep Medicine Authors: Aline Cristine Pereira e Silva, Maria Jos é dos Santos, Bruna Del Vechio Koike, Magna Suzana Alexandre Moreira, Daniel Leite Goes Gitai, Jorge Artur Peçanha de Miranda Coelho, Tiago Gomes de Andrade Source Type: research

Nocturnal gastroesophageal reflux increases the risk of daytime sleepiness in women
Daytime sleepiness is common in women and has negative health effects. Nocturnal gastroesophageal reflux (nGER) and snoring are risk factors for daytime sleepiness, but the effect of their interaction remains unknown. The aim of this study was to examine how nGER and snoring combined affected daytime sleepiness and involuntary falling asleep in women. (Source: Sleep Medicine)
Source: Sleep Medicine - October 13, 2018 Category: Sleep Medicine Authors: Shadi Amid H ägg, Össur I. Emilsson, Karl Franklin, Christer Janson, Eva Lindberg Tags: Original Article Source Type: research

School start time changes in the COMPASS study: associations with youth sleep duration, physical activity, and screen time
To date, no longitudinal population-based studies of school start times have been conducted within Canada. School schedule changes provided an opportunity to examine start times in association with youth sleep, physical activity, and screen time over time. (Source: Sleep Medicine)
Source: Sleep Medicine - October 12, 2018 Category: Sleep Medicine Authors: Karen A. Patte, Wei Qian, Adam G. Cole, Guy Faulkner, Jean-Philippe Chaput, Valerie Carson, Scott T. Leatherdale Source Type: research

Obstructive sleep apnea as a predictor of reduced heart rate variability
This study aimed to analyze the relationship between the occurrence of obstructive sleep apnea (OSA) and heart rate variability (HRV) in a group of patients with clinical suggestion of OSA. (Source: Sleep Medicine)
Source: Sleep Medicine - October 11, 2018 Category: Sleep Medicine Authors: Dominika Urbanik, Pawe ł Gać, Helena Martynowicz, Małgorzata Poręba, Maciej Podgórski, Marta Negrusz-Kawecka, Grzegorz Mazur, Małgorzata Sobieszczańska, Rafał Poręba Tags: Original Article Source Type: research

Suicidal Thought and Behavior in Individuals With Restless Legs Syndrome
Restless legs syndrome (RLS) is associated with an unrelenting urge to move at night, which can cause chronic sleeplessness, depression, and despondency, increasing risk of suicide. We aimed to determine frequency of suicidal ideation and behavior in RLS. (Source: Sleep Medicine)
Source: Sleep Medicine - October 11, 2018 Category: Sleep Medicine Authors: Kiran Sai Para, Christopher A. Chow, Keerthana Nalamada, Vikramjeet M. Kakade, Priyanka Chilakamarri, Elan D. Louis, Brian B. Koo Tags: Original Article Source Type: research

Efficacy of parent training incorporated in behavioral sleep interventions for children with autism spectrum disorder and/or intellectual disabilities: A systematic review
This article aims to systematically review the evidence on the efficacy of parent training that is incorporated within recent sleep interventions for children with ASD and/or ID. (Source: Sleep Medicine)
Source: Sleep Medicine - October 11, 2018 Category: Sleep Medicine Authors: Bernadette Kirkpatrick, Julia S. Louw, Geraldine Leader Source Type: research

Correlates of nocturnal sleep duration, nocturnal sleep variability, and nocturnal sleep problems in toddlers: Results from the GET UP! Study
To explore the correlates of nocturnal sleep duration, nocturnal sleep variability, and nocturnal sleep problems in a sample of Australian toddlers. (Source: Sleep Medicine)
Source: Sleep Medicine - October 11, 2018 Category: Sleep Medicine Authors: Zhiguang Zhang, Eduarda Sousa-S á, João Pereira, Jean-Philippe Chaput, Anthony Okely, Xiaoqi Feng, Rute Santos Tags: Original Article Source Type: research

Efficacy of bilevel ventilatory support in the treatment of stable patients with obesity hypoventilation syndrome: systematic review and meta-analysis
To systematically review the effects of bilevel ventilatory support (BVS) in patients with Obesity Hypoventilation Syndrome (OHS). (Source: Sleep Medicine)
Source: Sleep Medicine - October 10, 2018 Category: Sleep Medicine Authors: Caroline Persch Royer, Cl áudia Schweiger, Denise Manica, Luisi Rabaioli, Vinicius Guerra, Graciele Sbruzzi Tags: Original Article Source Type: research

Cord-blood vitamin D level and night sleep duration in preschoolers in the EDEN mother-child birth cohort
25-hydroxyvitamin D (25OHD) deficiency has been associated with sleep disorders in adults. Only three cross-sectional studies were performed in children; they showed an association between 25OHD deficiency and both obstructive sleep apnea syndrome and primary snoring. No longitudinal study has been performed in children from the general population. We analyzed the association between cord-blood vitamin D levels at birth and night-sleep duration trajectories for children between 2 and 5-6 years old in a non-clinical cohort. (Source: Sleep Medicine)
Source: Sleep Medicine - October 10, 2018 Category: Sleep Medicine Authors: Chu Yan Yong, Eve Reynaud, Anne Forhan, Patricia Dargent-Molina, Barbara Heude, Marie-Aline Charles, Sabine Plancoulaine, EDEN study group Tags: Original Article Source Type: research

Sleep deprivation: Prevalence and associated factors among adolescents in Saudi Arabia
This study estimates SD prevalence and associated factors within a nationally representative sample of adolescents in Saudi Arabia. (Source: Sleep Medicine)
Source: Sleep Medicine - October 10, 2018 Category: Sleep Medicine Authors: Maliha Nasim, Maissa Saade, Fadia AlBuhairan Tags: Original Article Source Type: research

Snoring and breathing pauses during sleep: interview survey of a United Kingdom population sample reveals a significant increase in the rates of sleep apnoea and obesity over the last 20 years - data from the UK Sleep Survey
(1) To determine the prevalence of snoring, breathing pauses during sleep, and obstructive sleep apnoea syndrome in the United Kingdom (UK) and determine the relation between these events and obesity and other sociodemographic variables. (2) To compare and integrate this data with published UK population data. (Source: Sleep Medicine)
Source: Sleep Medicine - October 9, 2018 Category: Sleep Medicine Authors: Matt Lechner, Charles E. Breeze, Maurice M. Ohayon, Bhik Kotecha Tags: Original Article Source Type: research

Withdrawal symptoms following dopaminergic treatment of RLS
The use of dopaminergic treatments in restless legs syndrome/Willis-Ekbom disease (RLS/WED) has been generally well known over the last decades, with three dopamine (DA) receptor agonists having been approved for the first-line treatment of RLS in most developed countries. The approval of these three drugs by the regulatory agencies was based on placebo-controlled studies, which showed therapeutic efficacy over the short-term with relatively minor toxicity [1]. (Source: Sleep Medicine)
Source: Sleep Medicine - October 9, 2018 Category: Sleep Medicine Authors: Diego Garcia-Borreguero Source Type: research

Response to “Prospective memory impairment in idiopathic REM sleep behavior disorder.”
iRBD is thought to be an intermediate state between normal and PD as the prodromal stage of synucleinopathy. We tried to observe the tendency for prospective memory (PM) impairments among three states. Although PD patients have been found to perform worse on PM tasks, there were different conclusions, which perhaps contribute to different PM methods. CAMPROMPT is a valid and reliable measure in clinical settings [1]; the Chinese version of CAMPROMPT whose reliability and validity have been established [2], has also been used in evaluating schizophrenia [3]. (Source: Sleep Medicine)
Source: Sleep Medicine - October 8, 2018 Category: Sleep Medicine Authors: Xudong Li Tags: Response Source Type: research

Evidence of Actigraphic and Subjective Sleep Disruption Following Mild Traumatic Brain Injury
Mild traumatic brain injuries (mTBI) are frequently associated with long-term, self-reported sleep disruption. Objective corroboration of these self-reports is sparse and limited by small sample sizes. The purpose of this study was to report on actigraphically-measured sleep outcomes in individuals with and without a history of recent mTBI in two U.S. cities (Boston, MA and Tucson, AZ). (Source: Sleep Medicine)
Source: Sleep Medicine - October 8, 2018 Category: Sleep Medicine Authors: Adam C. Raikes, Brieann C. Satterfield, William D.S. Killgore Tags: Original Article Source Type: research

Objective sleep alterations and long-term use of short or intermediate half-life benzodiazepine receptor agonists are risk factors for high blood pressure in individuals with insomnia: A study in 1272 individuals referred for sleep examinations
Given conflicting data in the literature, the aim of this study was to examine the risk of high blood pressure (HBP) associated with sleep alterations, measured during polysomnography, and long-term use of benzodiazepine receptor agonists in a large sample of individuals with insomnia. (Source: Sleep Medicine)
Source: Sleep Medicine - October 4, 2018 Category: Sleep Medicine Authors: Matthieu Hein, Jean-Pol Lanquart, Gw énolé Loas, Philippe Hubain, Paul Linkowski Source Type: research

Translation, cross-cultural adaptation and psychometric properties of the Sleep-Related Breathing Disordered −Pediatric Sleep Questionnaire for obese Thai children with obstructive sleep apnea
This study aimed to translate and cross-culturally adapt, from English to Thai, the Sleep-Related Breathing Disordered−Pediatric Sleep Questionnaire (SRBD-PSQ) and to determine its ps ychometric properties. (Source: Sleep Medicine)
Source: Sleep Medicine - October 4, 2018 Category: Sleep Medicine Authors: Khomkrip Longlalerng, Nuntigar Sonsuwan, Sureeporn Uthaikhup, Warunee Kumsaiyai, Patraporn Sitilertpisan, Patrinee Traisathit, Sainatee Pratanaphon Tags: Original Article Source Type: research

Evaluation of the efficacy of a dedicated table to improve CPAP adherence in children: A pilot study
Only a few studies have addressed strategies to improve continuous positive airway pressure (CPAP) adherence in children with obstructive sleep apnea. The aim of our study was to assess the efficacy of a table based on token economy to improve CPAP adherence. (Source: Sleep Medicine)
Source: Sleep Medicine - October 3, 2018 Category: Sleep Medicine Authors: Alexis Mendoza-Ruiz, Suela Dylgjeri, Florence Bour, Fr édéric Damagnez, Karl Leroux, Sonia Khirani Tags: Original Article Source Type: research

Effects of Suvorexant on the Insomnia Severity Index in Patients with Insomnia: Analysis of Pooled Phase 3 Data
Suvorexant is an orexin receptor antagonist that is approved in the US, Japan and Australia for the treatment of insomnia. Using outcomes from the Insomnia Severity Index (ISI) in the core registration studies, we explored suvorexant effects on sleep problems and their impact on daytime function. (Source: Sleep Medicine)
Source: Sleep Medicine - October 1, 2018 Category: Sleep Medicine Authors: W. Joseph Herring, Kathryn M. Connor, Ellen Snyder, Duane B. Snavely, Charles M. Morin, Christopher Lines, David Michelson Tags: Original Article Source Type: research

Endoscopically-Assisted Surgical Expansion (EASE) for the Treatment of Obstructive Sleep Apnea
The aim of this retrospective study was to evaluate the results of an outpatient surgical procedure named endoscopically-assisted surgical expansion (EASE) in expanding the maxilla to treat obstructive sleep apnea (OSA) in adolescent and adults. (Source: Sleep Medicine)
Source: Sleep Medicine - September 29, 2018 Category: Sleep Medicine Authors: Kasey Li, Stacey Quo, Christian Guilleminault Tags: Original Article Source Type: research

Slow Wave Sleep and Steroid Hormones
Since Jouvet and Dement ’s pioneering work in the 1950’-60’s, we know that sleep is not a single, inactive state but rather a complex, structured duality between rapid eye movement (REM) sleep and non-rapid eye movement (NREM) sleep [1, 2]. Using total, selective, acute and chronic sleep deprivation, the functional r ole of each sleep stage has been studied for decades. (Source: Sleep Medicine)
Source: Sleep Medicine - September 29, 2018 Category: Sleep Medicine Authors: Pierrick J. Arnal Tags: Editorial Source Type: research

Neutral supporting mandibular advancement device with tongue bead for passive myofunctional therapy: A long term follow-up study
s: Myofunctional therapy has been reported to be a valid adjunct treatment to OSA, but compliance was mentioned as an issue. We performed a prospective study on age matched randomized children submitted to myofunctional therapy (MFT) or to a functional device used during sleep (passive MFT). (Source: Sleep Medicine)
Source: Sleep Medicine - September 29, 2018 Category: Sleep Medicine Authors: Yu-Shu Huang, Li-Chuan Chuang, Miche`le Hervy-Auboiron, Teresa Paiva, Cheng-Hui Lin, Christian Guilleminault Tags: Original Article Source Type: research

Child Sleep Problems and Adult Mental Health in those Born at Term or Extremely Low Birth Weight
To examine associations between parent-reported child sleep walking or talking, nightmares, and trouble sleeping at age 8 and psychiatric problems in adulthood (age 30-35) in extremely low birth weight (ELBW;2500 g) control participants. (Source: Sleep Medicine)
Source: Sleep Medicine - September 29, 2018 Category: Sleep Medicine Authors: Jacob Young, Calan Savoy, Louis A. Schmidt, Saroj Saigal, Ryan J. Van Lieshout Tags: Original Article Source Type: research

White Matter Structural Differences in OSA Patients Experiencing Residual Daytime Sleepiness with High CPAP Use: A Non-Gaussian Diffusion MRI Study
To investigate factors associated with residual sleepiness in patients who were highly adherent to continuous positive airway pressure (CPAP). Nocturnal inactivity, comorbidities, concomitant medications, and, in particular, white matter (WM) differences using diffusion magnetic resonance imaging (MRI) were explored using a continuous-time random-walk (CTRW) model. (Source: Sleep Medicine)
Source: Sleep Medicine - September 28, 2018 Category: Sleep Medicine Authors: Jiaxuan Zhang, Terri E. Weaver, Zheng Zhong, Robyn A. Nisi, Kelly R. Martin, Alana D. Steffen, M. Muge Karaman, Xiaohong Joe Zhou Tags: Original Article Source Type: research

Sleep apnea screening is uncommon after stroke
To assess (1) pre and post-stroke screening for sleep apnea (SA) within a population-based study without an academic medical center, and (2) ethnic differences in post-stroke sleep apnea screening among Mexican Americans (MAs) and non-Hispanic whites (NHWs). (Source: Sleep Medicine)
Source: Sleep Medicine - September 26, 2018 Category: Sleep Medicine Authors: Devin L. Brown, Xiaqing Jiang, Chengwei Li, Erin Case, Cemal B. Sozener, Ronald D. Chervin, Lynda D. Lisabeth Tags: Brief Communication Source Type: research

Kafkas ’ Insomnia And Narrative Works
We thank Perciaccante and Coralli for their letter, highlighting the influence that insomnia had on the literary creativity of Franz Kafka [1, 2]. While we agree with the authors that Kafka considered insomnia to be his enemy, his lack of sleep also allowed him to work on his novels and stories at night; ie, the only time of the day when he could get the quietness he needed to write. In addition to the accurate examples given by Perciaccante and Coralli, we would like to add that this sentiment is reflected in a passage from a letter that Kafka wrote to Max Brod in 1922 (Perhaps there are other forms of writing, but I know...
Source: Sleep Medicine - September 26, 2018 Category: Sleep Medicine Authors: A. Iranzo, A. Stefani, B. H ögl, Joan Santamaria, SINBAR Tags: Letter to the Editor Source Type: research

Objectively confirmed prevalence of sleep-related rhythmic movement disorder in pre-school children
Childhood sleep-related rhythmic movement disorder (RMD) – sleep-related repetitive movements involving large muscle groups -can impair sleep quality, cause local injury and disturb household members. Previous parental reports indicate prevalence rates in children under 3 years of age between 5.5 and 67%. We studied the prevalence of RMD with objective home videosomnography. (Source: Sleep Medicine)
Source: Sleep Medicine - September 24, 2018 Category: Sleep Medicine Authors: Emily Gogo, Rachel M. van Sluijs, Trevor Cheung, Chloe Gaskell, Liam Jones, Nisreen A. Alwan, Catherine M. Hill Tags: Original Article Source Type: research

Excessive daytime sleepiness among children and adolescents: prevalence, correlates, and pubertal effects
To examine the prevalence and correlates of excessive daytime sleepiness (EDS) among Hong Kong children and adolescents. We investigated the potential roles of sex and puberty in modulating the occurrence of EDS. (Source: Sleep Medicine)
Source: Sleep Medicine - September 24, 2018 Category: Sleep Medicine Authors: Yaping Liu, Jihui Zhang, Shirley Xin Li, Ngan Yin Chan, Mandy Wai Man Yu, Siu Ping Lam, Joey Wing Yan Chan, Albert Martin Li, Yun Kwok Wing Tags: Original Article Source Type: research

Pediatric pulse oximetry-based OSA screening at different thresholds of the apnea-hypopnea index with an expression of uncertainty for inconclusive classifications
Assessments of pediatric obstructive sleep apnea (OSA) are underutilized across Canada due to a lack of resources. Polysomnography (PSG) measures OSA severity through the average number of apnea/hypopnea events per hour (AHI), but is resource intensive and requires a specialized sleep laboratory, which results in long waitlists and delays in OSA detection. Prompt diagnosis and treatment of OSA are crucial for children, as untreated OSA is linked to behavioral deficits, growth failure and negative cardiovascular consequences. (Source: Sleep Medicine)
Source: Sleep Medicine - September 22, 2018 Category: Sleep Medicine Authors: Ainara Garde, Xenia Hoppenbrouwer, Parastoo Dehkordi, Guohai Zhou, Aryannah Umedaly Rollinson, David Wensley, Guy A. Dumont, J Mark Ansermino Tags: Original Article Source Type: research

Insufficient sleep and suicidal ideation: A survey of 12,046 female adolescents
Adolescence is a time of adaptation to social, hormonal, and physical changes. During this critical time, adolescents develop self-identity and can experience mental instability. Emotional development during this period often affects adulthood. Depression that begins during adolescence has been reported to be more severe and long-lasting1. Also, external factors, such as the use of multimedia devices, playing video games, drinking alcohol, smoking, and consuming caffeine, have become threats to the mental health of adolescents2. (Source: Sleep Medicine)
Source: Sleep Medicine - September 21, 2018 Category: Sleep Medicine Authors: Woong-Sub Park, Kwang Ik Yang, Hyeyun Kim Tags: Original Article Source Type: research

A Study for the Mechanism of Sensory Disorder in Restless legs Syndrome based on Magnetoencephalography
In spite of the relatively high incidence rate, the etiology and pathogenesis of restless legs syndrome (RLS) are still unclear. Long-term drug treatments fail to achieve satisfying curative effects, which is reflected by rebound and augmentation of related symptoms. An electrophysiological endophenotype experiment was done to investigate the mechanism of somatosensory disorder among RLS patients. Together with 15 normal subjects as the control group, with comparable ages and genders to the RLS patients, 15 primitive RLS patients were scanned by Magnetoencephalography (MEG) under natural conditions, and the somatosensory e...
Source: Sleep Medicine - September 21, 2018 Category: Sleep Medicine Authors: Haoxiang Yang, Li Wang, Xin Li, Kun Wang, Yue Hou, Xiating Zhang, Zheng Chen, Chunyan Liu, Chunli Yin, Siqi Wu, Qian Huang, Yicong Lin, Yan Bao, Yuanyuan Chen, Yuping Wang Tags: Original Article Source Type: research

Sleep Phenotypes in Attention Deficit Hyperactivity Disorder
A case-control study was performed to test the hypothesis that children with attention deficit hyperactivity disorder (ADHD) have chronic sleep deprivation and may be classified into specific sleep-related phenotypes. (Source: Sleep Medicine)
Source: Sleep Medicine - September 20, 2018 Category: Sleep Medicine Authors: Silvia Miano, Ninfa Amato, Giuseppe Foderaro, Valdo Pezzoli, Gian Paolo Ramelli, Lorenzo Toffolet, Mauro Manconi Tags: Original Article Source Type: research

Mild Cognitive Impairment: Associations with sleep disturbance, Apolipoprotein e4, and sleep medications
This study examined: 1) if sleep disturbance increased the hazard of MCI; 2) if APOE e4 carriers with a sleep disturbance experience an increased risk of MCI; and, 3) if prescription sleep medications provide a protective effect against MCI. We hypothesized that sleep disturbance increases the hazard of MCI, and this relationship is stronger among APOE e4 carriers reporting a sleep disturbance, and we hypothesized that sleep medications decrease the hazard of MCI. (Source: Sleep Medicine)
Source: Sleep Medicine - September 20, 2018 Category: Sleep Medicine Authors: Shanna L. Burke, Tianyan Hu, Christine E. Spadola, Tan Li, Mitra Naseh, Aaron Burgess, Tamara Cadet Tags: Original Article Source Type: research

Sleep architecture in adults with epilepsy: a systematic review
To assess whether sleep architecture differs in subgroups of adults with epilepsy or in adults with epilepsy compared to control populations. (Source: Sleep Medicine)
Source: Sleep Medicine - September 20, 2018 Category: Sleep Medicine Authors: Pedro Sudbrack-Oliveira, Lucas Lima Najar, Nancy Foldvary-Schaefer, Marleide da Mota Gomes Tags: Review Article Source Type: research

Sleep and libido in men with obstructive sleep apnea syndrome
The objectives of this study were to investigate the relationship between a low libido and objective sleep parameters as well as mood disturbances in patients with obstructive sleep apnea syndrome (OSA). (Source: Sleep Medicine)
Source: Sleep Medicine - September 20, 2018 Category: Sleep Medicine Authors: Jun Kyu Mun, Su Jung Choi, Mi-Ri Kang, Seung Bong Hong, Eun Yeon Joo Tags: Original Article Source Type: research

Correlation between HLA-DQB1*06:02 and narcolepsy with and without cataplexy: approving a safe and sensitive genetic test in four major ethnic groups. A Systematic Meta-analysis
we performed a meta-analysis to assess the usefulness of HLA testing for Narcolepsy diagnosis in four major ethnical groups: Asians, Afro-Americans, Amerindians, Caucasians. (Source: Sleep Medicine)
Source: Sleep Medicine - September 20, 2018 Category: Sleep Medicine Authors: C. Capittini, A. De Silvestri, M. Terzaghi, V. Scotti, C. Rebuffi, A. Pasi, R. Manni, M. Martinetti, C. Tinelli Tags: Review Article Source Type: research

The Spectrum of Sleep Disordered Breathing in Joubert Syndrome
10-year-old male and 8-year-old female siblings presented for developmental evaluation and insomnia. Both were term babies with no prenatal or post-natal complications. In early infancy daytime abnormal respiratory patterns existed with episodes of rapid breathing and apnea. These resolved in the brother only. Frequent nighttime awakenings occurred with no snoring. On examination, they had normal BMI, dysmorphic features including hypertelorism, small earlobes, broad mouth, intermittent tongue protrusion and anteverted nostrils. (Source: Sleep Medicine)
Source: Sleep Medicine - September 19, 2018 Category: Sleep Medicine Authors: Mandeep Rana, Mugdha Mohanty Tags: Images in Sleep Medicine Source Type: research

Near-total absence of REM sleep co-occurring with normal cognition: an update of the 1984 paper
REM sleep (REMS) is considered vital for supporting well-being and normal cognition. However, it remains unclear if and how decreases in REMS impair cognitive abilities. Rare case studies of patients with REMS abolishment due to pontine lesions remain sporadic, and formal evaluation of cognitive status is lacking. In 1984, Lavie and colleagues described the case of Y.C. – a man with a pontine lesion and near-total absence of REMS who led a normal life. Here, we set out to re-evaluate this individual’s REMS status 30 years after the original report, and formally assess his cognitive abilities. (Source: Sleep Medicine)
Source: Sleep Medicine - September 18, 2018 Category: Sleep Medicine Authors: Efrat Magidov, Hanna Hayat, Omer Sharon, Fani Andelman, Shlomit Katzav, Peretz Lavie, Riva Tauman, Yuval Nir Tags: Brief Communication Source Type: research

Response to “Smoking, co-morbidities and narcolepsy”
We thank Dr. Dhillon and colleagues for their interest in our recent paper and their important consideration of the impact of smoking on comorbidities associated with narcolepsy [1]. Their report that patients with narcolepsy with cataplexy who currently smoke tobacco experience more severe and frequent cataplexy is certainly concerning and is a noteworthy issue that warrants further attention. Concurrently, it will also be necessary to consider the effects of nicotine on excessive daytime sleepiness (EDS), given the reported perception among patients with narcolepsy that nicotine reduces EDS [2]. (Source: Sleep Medicine)
Source: Sleep Medicine - September 18, 2018 Category: Sleep Medicine Authors: Alexander Cohen, Jay Mandrekar, Erik K. St. Louis, Michael H. Silber, Suresh Kotagal Tags: Response Source Type: research

Larks and owls and disease manifestation
Clocks are ubiquitous and allow the synchronization of biological functions at the cellular, organ and behavioral level to the immutable light and dark cycle of daily existence. The oscillation of core body temperature and the inexorable cycle of waking and sleep are familiar and obvious examples of circadian rhythms. It is less obvious than than the knowledge about how biological clocks are interwoven into virtually every aspect of physiological functioning from the cellular to organ level. These oscillations in single cells and organs are regulated by the environmental light/dark cycle and social cues which serve to link...
Source: Sleep Medicine - September 18, 2018 Category: Sleep Medicine Authors: William C. Orr Tags: Editorial Source Type: research

Differences in diffusion tensor imaging changes between narcolepsy with and without cataplexy
In this study, we aimed to clarify the white matter changes in narcolepsy patients both with and without cataplexy and compared them with healthy adults to evaluate microstructural differences in the brain. (Source: Sleep Medicine)
Source: Sleep Medicine - September 18, 2018 Category: Sleep Medicine Authors: F. Irsel Tezer, Abidin Erdal, Sadiye Gumusyayla, Arzu Ceylan Has, Rahsan Gocmen, Kader K. Oguzv Tags: Original Article Source Type: research

Perinatal risk factors for obstructive sleep apnea syndrome in children
The aim of this study was to determine whether specific perinatal factors are associated with obstructive sleep apnea syndrome (OSAS) in children. (Source: Sleep Medicine)
Source: Sleep Medicine - September 17, 2018 Category: Sleep Medicine Authors: Yafei Tan, Dan Zhang, Hui Mei, Hong Mei, Zhengmin Qian, Katherine A. Stamatakis, Savannah S. Jordan, Yan Yang, Shaoping Yang, Bin Zhang Tags: Original Article Source Type: research

Sleep habits in infants: the role of maternal education
The objective of this study was to assess the impact of maternal education on the development of infants ’ sleep habits (SHs). (Source: Sleep Medicine)
Source: Sleep Medicine - September 17, 2018 Category: Sleep Medicine Authors: Rosa M.A. Martins, Joana R.A. Oliveira, Catarina C.G. Salgado, B árbara L.S. Marques, Lia C.F. Oliveira, Graça R. Oliveira, Teresa S. Rodrigues, Rosário T. Ferreira Source Type: research

Daytime autonomic activity in idiopathic rapid eye movement sleep behavior disorder: a preliminary study
To investigate cardiovascular and sudomotor autonomic functions in patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) during wakefulness compared to patients with Parkinson ’s disease (PD) and healthy subjects. (Source: Sleep Medicine)
Source: Sleep Medicine - September 17, 2018 Category: Sleep Medicine Authors: Camilla Rocchi, Fabio Placidi, Claudio Liguori, Chiara Del Bianco, Benedetta Lauretti, Marina Diomedi, Antonio Pisani, Nicola B. Mercuri, Francesca Izzi Tags: Original Article Source Type: research

Editorial Board
(Source: Sleep Medicine)
Source: Sleep Medicine - September 16, 2018 Category: Sleep Medicine Source Type: research

Nocturnal motor behaviors with unexpected EEG and brain MRI findings
Arousal Disorders (DOA) are usually childhood parasomnias. When DOA persist during adulthood they can be difficult to distinguish from other nocturnal behaviors, particularly sleep-related hypermotor epilepsy (SHE). We observed a patient with nocturnal behaviors clinically suggestive of DOA in which EEG and brain MRI features unexpectedly posed a challenge in the differential diagnosis with SHE. A 28-year-old woman complained of abrupt nocturnal awakenings followed by sleepwalking and sometimes running out of the room. (Source: Sleep Medicine)
Source: Sleep Medicine - September 6, 2018 Category: Sleep Medicine Authors: Tommaso Baldini, Giuseppe Loddo, Francesco Mignani, Laura Licchetta, Francesca Bisulli, Paolo Tinuper, Federica Provini Tags: Letter to the Editor Source Type: research