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Condition: Depression
Drug: Insulin

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Total 69 results found since Jan 2013.

Towards a multi protein and mRNA expression of biological predictive and distinguish model for post stroke depression.
Authors: Yue Y, Jiang H, Liu R, Yin Y, Zhang Y, Liang J, Li S, Wang J, Lu J, Geng D, Wu A, Yuan Y Abstract Previous studies suggest that neurotrophic factors participate in the development of stroke and depression. So we investigated the utility of these biomarkers as predictive and distinguish model for post stroke depression (PSD). 159 individuals including PSD, stroke without depression (Non-PSD), major depressive disorder (MDD) and normal control groups were recruited and examined the protein and mRNA expression levels of vascular endothelial growth factor (VEGF), vascular endothelial growth factor receptors (V...
Source: Oncotarget - August 18, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

The relation between insulin ‐like growth factor 1 levels and risk of depression in ischemic stroke
ConclusionThe data showed that low serum IGF‐1 levels at admission are associated with a high risk of developing PSD, suggesting that these alterations might be involved in the pathophysiology of depression symptoms in stroke patients.
Source: International Journal of Geriatric Psychiatry - August 23, 2017 Category: Geriatrics Authors: Wei Zhang, Wo Wang, Li Kuang Tags: RESEARCH ARTICLE Source Type: research

The Relationship between Glucose Control & Cognitive Function in People with Diabetes after a Lacunar Stroke.
CONCLUSION: This analysis of lacunar stroke patients with diabetes demonstrates a relationship between A1C and change in cognitive scores over time. Intervention studies are needed in order to delineate if better glucose control could slow the rate of cognitive decline in this high risk population. PMID: 33481011 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - January 22, 2021 Category: Endocrinology Authors: Cukierman-Yaffe T, McClure LA, Thomas R, Bosch J, Sharma M, Gerstein HC, Benavente O Tags: J Clin Endocrinol Metab Source Type: research

Insulin resistance as estimated by homeostasis model assessment predicts incident post-stroke depression in Chinese subjects from ischemic stroke
Previous studies suggested that insulin resistance (IR) may be a significant causal risk factor for cardiovascular events and depression independent of other risk factors. In this prospective, we assess the value of Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) at admission to predict post-stroke depression (PSD) later developed at 3 months follow-up.
Source: Journal of Affective Disorders - February 2, 2018 Category: Neurology Authors: Han-Cheng Qiu, Hui-Zhen Liu, Xuemei Li, Xianwei Zeng, Ji-Zong Zhao Tags: Research paper Source Type: research

Sex differences in the association between stroke risk factors and pre-clinical predictors of stroke in the childhood determinants of Adult Health study
CONCLUSIONS: Smoking, SBP and glucose affect carotid structure and function more in women than men with some of this risk due to co-occurring risk factors.PMID:37391336 | DOI:10.1016/j.atherosclerosis.2023.06.077
Source: Atherosclerosis - June 30, 2023 Category: Cardiology Authors: Mohammad Shah Marie-Jeanne Buscot Jing Tian Hoang T Phan Thomas H Marwick Terence Dwyer Alison Venn Seana Gall Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Oversleeping: The Effects and Health Risks of Sleeping Too Much
This article originally appeared on the Amerisleep blog. Rosie Osmun is the Creative Content Manager at Amerisleep, a progressive memory foam mattress brand focused on eco-friendly sleep solutions. Rosie writes more posts on the Amerisleep blog about the science of sleep, eco-friendly living, leading a healthy lifestyle and more. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - January 29, 2016 Category: Consumer Health News Source Type: news

Role of TREK-1 in Health and Disease, Focus on the Central Nervous System
Conclusion and Perspectives Since their cloning 20 years ago, the physiological importance of TREK-1 channels has continued to grow (Figure 3). Today, TREK-1 channels have been shown to be important and their presence is essential in a number of physiopathological processes. Their involvement in these different processes demonstrate the necessity to design pharmacological modulators, activators or inhibitors, of these channels to correct any TREK-1-related dysfunctions. Despites a number of studies and many molecule screenings, only few putative new drugs were identified. The activators belonging to the ML and BL series ...
Source: Frontiers in Pharmacology - April 10, 2019 Category: Drugs & Pharmacology Source Type: research

Can sleeping too much cause chronic diseases?
Conclusion This 2010 survey data from middle aged and older adults from 14 US states suggests an association between shorter and longer than optimal sleep duration and three chronic diseases. The optimal amount of sleep recommended varies by different organisations, but tends to be either seven to eight or seven to nine hours a night for an adult. However, though the study benefits from its large sample size of over 50,000 adults it has significant limitations. Cross sectional study design Most importantly, the cross sectional study design which has assessed sleep duration and disease presence at the same time cannot prov...
Source: NHS News Feed - October 4, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Diabetes Source Type: news

How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you… Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China. I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1 We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004. Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

Sleep Apnea and the Effects on Your Health
Sleep is not always a benign state. Snoring may not be harmless. In fact, a related condition that affects breathing during sleep may have important consequences. This disorder, sleep apnea, can have significant effects on your overall health. There are certain symptoms and signs associated with obstructive sleep apnea that can affect day-to-day life. Excessive daytime sleepiness, mood complaints like anxiety or depression, or difficulty with thinking may undermine concentration or memory. However, untreated sleep apnea can have other unwanted side effects. Sleep apnea may increase blood pressure, lead to insulin resista...
Source: About Sleep Disorders - March 21, 2014 Category: Sleep Medicine Source Type: news

Depression in the Context of Medical Disorders: New Pharmacological Pathways Revisited
In conclusion a hypothetic model for the implication of actual findings in everyday clinical practice is proposed. In this context personalized treatment could be used to tailor treatment to specific individuals according to their clinical endophenotypes. Moreover a potential target for the development of novel intervention strategies might be used.Neurosignals 2017;25:54 –73
Source: Neurosignals - October 17, 2017 Category: Neurology Source Type: research

Depression in the Context of Medical Disorders: New Pharmacological Pathways Revisited.
In conclusion a hypothetic model for the implication of actual findings in everyday clinical practice is proposed. In this context personalized treatment could be used to tailor treatment to specific individuals according to their clinical endophenotypes. Moreover a potential target for the development of novel intervention strategies might be used. PMID: 29041003 [PubMed - as supplied by publisher]
Source: Neuro-Signals - October 17, 2017 Category: Neurology Authors: Lang UE, Walter M Tags: Neurosignals Source Type: research

Depression in the Context of Medical Disorders: New Pharmacological Pathways Revisited
In conclusion a hypothetic model for the implication of actual findings in everyday clinical practice is proposed. In this context personalized treatment could be used to tailor treatment to specific individuals according to their clinical endophenotypes. Moreover a potential target for the development of novel intervention strategies might be used.Neurosignals 2017;25:54 –73
Source: Neurosignals - October 25, 2017 Category: Neurology Source Type: research

Depression Is More than a Stigma
Manoj K. Pandey is Lecturer in Economics, Australian National University; Vani S. Kulkarni is Lecturer in Sociology, University of Pennsylvania; and Raghav Gaiha is (Hon. ) Professorial Research Fellow, Global Development Institute, University of ManchesterBy Manoj K. Pandey, Vani S. Kulkarni and Raghav GaihaCanberra, Philadelphia and Manchester, Mar 20 2019 (IPS) Depression is often distinguished from other non-communicable diseases or NCDs (e.g., cancer, diabetes, cardio-vascular diseases, hypertension) because of the stigma attached to it. Among other consequences, those suffering from depression are often denied access...
Source: IPS Inter Press Service - Health - March 20, 2019 Category: International Medicine & Public Health Authors: Manoj K. Pandey - and Raghav Gaiha Tags: Featured Global Headlines Health Human Rights TerraViva United Nations Women's Health Source Type: news