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Total 543 results found since Jan 2013.

Modafinil for the Improvement of Patient Outcomes Following Traumatic Brain Injury
Conclusion. Modafinil is a central nervous system stimulant with well-established effectiveness in the treatment of narcolepsy and shift-work sleep disorder. There is conflicting evidence about the benefits of modafinil in the treatment of fatigue and EDS secondary to TBI. One randomized, controlled study states that modafinil does not significantly improve patient wakefulness, while another concludes that modafinil corrects EDS but not fatigue. An observational study provides evidence that modafinil increases alertness in fatigued patients with past medical history of brainstem diencephalic stroke or multiple sclerosis. ...
Source: Innovations in Clinical Neuroscience - April 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review excessive daytime sleep fatigue head injury modafinil stroke TBI traumatic brain injury Source Type: research

Assessment of Stroke Risk Factors in Southern Arizona (P02.054)
CONCLUSIONS: Despite a higher incidence of stroke, Hispanic concern regarding stroke risk factors is much lower than non-Hispanics. This suggests that knowledge linking risk factors for stroke and incident stroke may be lacking in Hispanic communities. Lessened concern regarding stroke risk factors may contribute to an increase incidence in stroke and to a worse outcome in this population. Hispanics increased interest in health promotion programs may afford one approach to addressing this problem. This data suggest that despite historically worse stroke outcomes, preventative efforts may be beneficial in raising stroke ris...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Nokes, B., Sim, Y., Byreddy, S., Chong, J., Drake, K., Labiner, D., Coull, B. Tags: P02 Cerebrovascular Disease II Source Type: research

MyRisk_Stroke Calculator: A Personalized Stroke Risk Assessment Tool for the General Population.
CONCLUSIONS: The MyRisk_Stroke Calculator is a simple method of disseminating information to the general population about their stroke risk. PMID: 24465256 [PubMed]
Source: Journal of Clinical Neurology - December 2, 2014 Category: Neurology Tags: J Clin Neurol Source Type: research

The Impact of Vascular Risk Factors on Post-stroke Cognitive Impairment: The Nor-COAST Study
Discussion: Our findings indicate that a focal stroke lesion might be related to pathophysiological processes leading to global cognitive impairment. The poorer prognosis of PSCI in patients with vascular risk factors emphasizes the need for further research on complex vascular risk factor interventions to prevent PSCI.
Source: Frontiers in Neurology - August 5, 2021 Category: Neurology Source Type: research

Application of Machine Learning Techniques to Identify Data Reliability and Factors Affecting Outcome After Stroke Using Electronic Administrative Records
Conclusion: Electronic administrative records from this cohort produced reliable outcome prediction and identified clinically appropriate factors negatively impacting most outcome variables following hospital admission with stroke. This presents a means of future identification of modifiable factors associated with patient discharge destination. This may potentially aid in patient selection for certain interventions and aid in better patient and clinician education regarding expected discharge outcomes.
Source: Frontiers in Neurology - September 27, 2021 Category: Neurology Source Type: research

Purpose in life and reduced incidence of stroke in older adults: 'The Health and Retirement Study'
Conclusion: Among older American adults, greater purpose in life is linked with a lower risk of stroke.
Source: Journal of Psychosomatic Research - March 1, 2013 Category: Psychiatry & Psychology Authors: Eric S. Kim, Jennifer K. Sun, Nansook Park, Christopher Peterson Tags: Original Articles Source Type: research

Stroke incidence and risk factors in Havana and Matanzas, Cuba
Conclusions Stroke incidence was similar to rates reported in developed countries and lower than that in low- to middle-income countries. Given that diabetes mellitus, heart disease, arterial hypertension, smoking, APOE4, etc. are associated with higher mortality rates, they will require separate analysis in a study of stroke risk factors.
Source: Neurologia - September 12, 2015 Category: Neurology Source Type: research

The Risk Stratification and Stroke Prevention Therapy Care Gap in Canadian Atrial Fibrillation Patients
Conclusions In a large Canadian AF population, primary care physicians did not provide a stroke or bleeding risk in a substantial proportion of their AF patients. When estimates were provided, they were on the basis of a predictive stroke and bleeding risk index in less than half of the patients. Furthermore, there was under- and overestimation of stroke and bleeding risk in a substantial proportion of patients. As many as 1 in 3 patients receiving warfarin have their TTR < 60%. These findings suggest an opportunity to enhance knowledge translation to primary care physicians.
Source: Canadian Journal of Cardiology - October 23, 2015 Category: Cardiology Source Type: research

Molecular mechanisms of cognitive impairment associated with stroke
AbstractStroke is the second leading cause of death after coronary heart disease in developed countries and is the greatest cause of disability and cognitive impairment. Risk factors for cognitive impairment and dementia after stroke are multifactorial including older age, family history, hypertension, arterial fibrillation, diabetes, genetic variants, low educational status, vascular comorbidities, prior transient ischaemic attack or recurrent stroke, depressive illness duration of a stroke, location, volume, intensity, and degree of neuronal degeneration, location and size of infarction after stroke, time interval after ...
Source: Metabolic Brain Disease - January 14, 2022 Category: Neurology Source Type: research

Educational and homeownership inequalities in stroke incidence: a population-based longitudinal study of mid-aged women
Conclusions: Lower education level is associated with increased stroke risk in mid-aged women, and is partially mediated by known risk factors, particularly lifestyle and biological factors. Non-homeownership is associated with increased stroke risk, but the underlying mechanism is unclear.
Source: The European Journal of Public Health - March 26, 2014 Category: Journals (General) Authors: Jackson, C. A., Jones, M., Mishra, G. D. Tags: Cardiovascular disease Source Type: research

Estimation of 10-Year Risk of Death from Coronary Heart Disease, Stroke, and Cardiovascular Disease in a Pooled Analysis of Japanese Cohorts: EPOCH-JAPAN.
CONCLUSIONS: Risk equations in the present study can adequately estimate the absolute 10-year risk of death from CHD, stroke, and CVD. Future work will evaluate the system as an education and risk communication tool for primary prevention of CHD and stroke. PMID: 33041313 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - October 14, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Epidemiology of classical risk factors in stroke patients in the Middle East
The Middle East (ME) is an ethnically and economically diverse region. A systematic review of all stroke studies conducted in the ME was carried out, with the aim of determining the prevalence of classic vascular risk factors (CRFs) across this region. Additionally, the prevalence of CRFs in the ME was compared to that of a US cohort. Prospective and retrospective ME stroke studies published from 1994 to 2014 were searched for that specifically reported on the prevalence of CRFs. The Z test for proportions was used to determine the significance of differences in CRF rates between the ME and non‐ME studies. A total of 21...
Source: European Journal of Neurology - June 4, 2015 Category: Neurology Authors: R. Behrouz, C. J. Powers Tags: Review Article Source Type: research

Elucidating the Association Between Depressive Symptoms, Coronary Heart Disease, and Stroke in Black and White Adults: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study Epidemiology
Conclusions Proximal depressive symptoms were associated with incident fatal and nonfatal stroke and CVD death even after controlling for multiple explanatory factors, further supporting the urgent need for timely management of depressive symptoms.
Source: JAHA:Journal of the American Heart Association - August 11, 2016 Category: Cardiology Authors: Moise, N., Khodneva, Y., Richman, J., Shimbo, D., Kronish, I., Safford, M. M. Tags: Quality and Outcomes Epidemiology Source Type: research