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Condition: Heart Disease
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Total 119 results found since Jan 2013.

Blood Flow Restriction Exercise Attenuates the Exercise-Induced Endothelial Progenitor Cell Response in Healthy, Young Men
Conclusion In summary, this is the first study to show that BFR exercise did not augment EPC response to exercise, and in fact blunted the EPC response to low load unilateral KE exercise in young, healthy males. Ethics Statement This study was carried out in accordance with the recommendations of Edinburgh Napier University Research and Ethics Governance Committee. The study was ethically approved by Edinburgh Napier University Research and Ethics Governance Committee. All participants gave written informed consent in accordance with the Declaration of Helsinki. Author Contributions MR, RM, AP, CW, GF-J designed the s...
Source: Frontiers in Physiology - April 16, 2019 Category: Physiology Source Type: research

10 Biggest Myths About Sleeping, According To Researchers
(CNN) — Hey, sleepyheads. What you believe about sleep may be nothing but a pipe dream. Many of us have notions about sleep that have little basis in fact and may even be harmful to our health, according to researchers at NYU Langone Health’s School of Medicine, who conducted a study published Tuesday in the journal Sleep Health. “There’s such a link between good sleep and our waking success,” said lead study investigator Rebecca Robbins, a postdoctoral research fellow in the Department of Population Health at NYU Langone Health. “And yet we often find ourselves debunking myths, whether ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 16, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Healthwatch News CNN Sleep Source Type: news

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Contemporary prevalence of carotid stenosis in patients presenting with ischaemic stroke.
CONCLUSION: Carotid stenosis is common, affecting one in five patients presenting with stroke or TIA. Careful MDT discussion may avoid unnecessary intervention and should be the standard of care. PMID: 30938840 [PubMed - as supplied by publisher]
Source: The British Journal of Surgery - April 1, 2019 Category: Surgery Authors: Cheng SF, Brown MM, Simister RJ, Richards T Tags: Br J Surg Source Type: research

Prediction Model for the Efficacy of Folic Acid Therapy on Hyperhomocysteinaemia based on genetic risk score methods.
Abstract No risk assessment tools for the efficacy of folic acid treatment for hyperhomocysteinaemia (HHcy) have been developed. We aimed to use two common genetic risk score (GRS) methods to construct prediction models for the efficacy of folic acid therapy on HHcy, and the best gene-environment prediction model was screened out. A prospective cohort study enrolling 638 HHcy patients was performed. We used logistic regression model to estimate the associations of two GRS methods with the efficacy. Performances were compared using area under the receiver operating characteristic curve (AUC). The simple count genet...
Source: The British Journal of Nutrition - April 1, 2019 Category: Nutrition Authors: Du B, Zhang C, Yue L, Ren B, Zhao Q, Li D, He Y, Zhang W Tags: Br J Nutr Source Type: research

Study: 3+ Eggs A Day Increases Risk Of Heart Disease, Early Death
(CNN) — It’s been debated for years: Are eggs good or bad for you? People who eat three or four eggs a day — or any equivalent of 300 mg of dietary cholesterol — have a higher risk of both heart disease and early death compared to those who eat fewer eggs, new research finds. “Eggs, especially the yolk, are a major source of dietary cholesterol,” wrote Victor Zhong, lead author and a postdoctoral fellow in the Department of Preventive Medicine at Northwestern University Feinberg School of Medicine in Chicago. In a study published Friday in the medical journal JAMA, he and his colleagues ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 15, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Eggs Source Type: news

Substantial Cardiovascular Morbidity in Adults with Lower-Complexity Congenital Heart Disease.
CONCLUSIONS: Individuals with lower-complexity ACHD had higher burden of adverse cardiovascular events relative to the general population that was unaccounted for by conventional cardiovascular risk factors. These findings highlight the need for closer surveillance of patients with mild to moderate ACHD and further investigation into management and mechanisms of cardiovascular risk unique to this growing population of high-risk adults. PMID: 30813762 [PubMed - as supplied by publisher]
Source: Circulation - February 27, 2019 Category: Cardiology Authors: Saha P, Potiny P, Rigdon J, Morello M, Tcheandjieu C, Romfh A, Fernandes SM, McElhinney DB, Bernstein D, Lui GK, Shaw GM, Ingelsson E, Priest JR Tags: Circulation Source Type: research

Is Brexit a Health Hazard?
FRIDAY, Feb. 1, 2019 -- Thousands more deaths from heart disease and stroke could occur in England if Brexit goes ahead, researchers warn. Fruits and vegetables play an important role in heart health, and the United Kingdom is highly dependent on...
Source: Drugs.com - Daily MedNews - February 1, 2019 Category: General Medicine Source Type: news

BMI and Mortality in UK Biobank: Revised Estimates Using Mendelian Randomization.
CONCLUSIONS: Results support a causal role of higher BMI in increasing the risk of all-cause mortality and mortality from several specific causes. PMID: 30358150 [PubMed - in process]
Source: Obesity - October 27, 2018 Category: Eating Disorders & Weight Management Authors: Wade KH, Carslake D, Sattar N, Davey Smith G, Timpson NJ Tags: Obesity (Silver Spring) Source Type: research

The 2017 hormone therapy position statement of The North American Menopause Society
The 2017 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the 2012 Hormone Therapy Position Statement of The North American Menopause Society and identifies future research needs. An Advisory Panel of clinicians and researchers expert in the field of women's health and menopause was recruited by NAMS to review the 2012 Position Statement, evaluate new literature, assess the evidence, and reach consensus on recommendations, using the level of evidence to identify the strength of recommendations and the quality of the evidence. The Panel's recommendations were reviewed and approved by...
Source: Menopause - October 25, 2018 Category: OBGYN Tags: Commemorative Papers Source Type: research

Clinical Impact of 5  Years of Liraglutide Treatment on Cardiovascular Risk Factors in Patients with Type 2 Diabetes Mellitus in a Real-Life Setting in Italy: An Observational Study
ConclusionIn patients prolonging treatment with liraglutide for 5  years, the benefits in relation to metabolic control and CV risk factors are maintained. The UKPDS risk scores suggest that liraglutide is associated with a reduced CHD risk, but not with a reduced stroke risk.
Source: Diabetes Therapy - September 20, 2018 Category: Endocrinology Source Type: research

Studies: Low-Dose Aspirin May Not Prevent Initial Heart Attack, Stroke
Taking a low-dose aspirin every day has long been known to cut the chances of another heart attack, stroke or other heart problem in people who already have had one, but the risks don’t outweigh the benefits for most other folks, major new research finds. Although it’s been used for more than a century, aspirin’s value in many situations is still unclear. The latest studies are some of the largest and longest to test this pennies-a-day blood thinner in people who don’t yet have heart disease or a blood vessel-related problem. One found that aspirin did not help prevent first strokes or heart attacks...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 27, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch aspirin Source Type: news

Scientific expert reaction to Cochrane Review on omega-3 fatty acids
This study provides no evidence to suggest that this dietary advice should change.”Read the press releaseSee the media coverageDeclared interestsProf Tim Chico: “No conflicts.”Dr Ian Johnson: “Ian Johnson has previously held honorary academic appointments in the medical school at the University of East Anglia.”Prof Tom Sanders: “Scientific governor of British Nutrition Foundation, Honorary Director of Nutrition HEART UK.”The Science Media CentreThe Science Media Centre is an independent venture working to promote the voices, stories and views from the scientific community to the news media when science is in ...
Source: Cochrane News and Events - July 17, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Large-Scale Phenome-Wide Association Study of PCSK9 Variants Demonstrates Protection Against Ischemic Stroke Original Articles
Conclusions: This result represents the first genetic evidence in a large cohort for the protective effect of PCSK9 inhibition on ischemic stroke and corroborates exploratory evidence from clinical trials. PCSK9 inhibition was not associated with variables other than those related to LDL (low-density lipoprotein) cholesterol, atherosclerosis, and type 2 diabetes mellitus, suggesting that other effects are either small or absent.
Source: Circulation: Cardiovascular Genetics - July 11, 2018 Category: Cardiology Authors: Rao, A. S., Lindholm, D., Rivas, M. A., Knowles, J. W., Montgomery, S. B., Ingelsson, E. Tags: Cardiovascular Disease, Diabetes, Type 2, Genetic, Association Studies, Ischemic Stroke Original Articles Source Type: research

Age-specific association between blood pressure and vascular and non-vascular chronic diseases in 0·5 million adults in China: a prospective cohort study
Publication date: June 2018Source: The Lancet Global Health, Volume 6, Issue 6Author(s): Ben Lacey, Sarah Lewington, Robert Clarke, Xiang Ling Kong, Yiping Chen, Yu Guo, Ling Yang, Derrick Bennett, Fiona Bragg, Zheng Bian, Shaojie Wang, Hua Zhang, Junshi Chen, Robin G Walters, Rory Collins, Richard Peto, Liming Li, Zhengming Chen, Junshi Chen, Zhengming ChenSummaryBackgroundThe age-specific association between blood pressure and vascular disease has been studied mostly in high-income countries, and before the widespread use of brain imaging for diagnosis of the main stroke types (ischaemic stroke and intracerebral haemorrh...
Source: The Lancet Global Health - July 10, 2018 Category: International Medicine & Public Health Source Type: research