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Condition: Heart Failure
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Total 65730 results found since Jan 2013.
RBM25 regulates hypoxic cardiomyocyte apoptosis through CHOP-associated endoplasmic reticulum stress
Cell Stress Chaperones. 2023 Sep 22. doi: 10.1007/s12192-023-01380-7. Online ahead of print.ABSTRACTIschemic heart failure (HF) is one of the leading causes of global morbidity and mortality; blocking the apoptotic cascade could help improve adverse outcomes of it. RNA-binding motif protein 25 (RBM25) is an RNA-binding protein related to apoptosis; however, its role remains unknown in ischemic HF. The main purpose of this study is to explore the mechanism of RBM25 in ischemic HF. Establishing an ischemic HF model and oxygen-glucose deprivation (OGD) model. ELISA was performed to evaluate the BNP level in the ischemic HF mo...
Source: Cell Stress and Chaperones - September 22, 2023 Category: Cytology Authors: Ziwei Zhu Jie Pu Yongnan Li Jianshu Chen Hong Ding Anyu Zhou XiaoWei Zhang Source Type: research
WVU Heart and Vascular Institute Partners with Story Health to Improve Access to Specialty Care
The WVU Heart and Vascular Institute and Story Health, a health technology and services company building specialty care models for the future, today announced a new collaboration to improve access to specialty care for patients with heart failure. The partnership combines the WVU Heart...
Source: PRWeb: Medical Pharmaceuticals - September 21, 2023 Category: Pharmaceuticals Tags: PDT LIC Source Type: news
NT-proBNP and High Intensity Care for Acute Heart Failure NT-proBNP and High Intensity Care for Acute Heart Failure
This study assessed the role of NT-proBNP in patients receiving rapid up-titration of guideline-recommended medical therapy for acute heart failure.European Heart Journal
Source: Medscape Today Headlines - September 21, 2023 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Testosterone Replacement Therapy and Cardiovascular Disease: Balancing Safety and Risks in Hypogonadal Men
Curr Cardiol Rep. 2023 Sep 21. doi: 10.1007/s11886-023-01935-1. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: The purpose of this review is to analyze the link between testosterone replacement therapy (TRT) and adverse cardiovascular (CV) events. RECENT FINDINGS: A few published studies suggest a link between TRT and CV events. These studies contained flaws, and many other studies reveal a reduction in CV events. Hypogonadism is associated with increased mortality in men with CVD. TRT in hypogonadal men can improve many CVD risk factors, reduce QT interval prolongation, lead to better outcomes in heart failure patients,...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Kelli Blackwell Michele Blackwell Thomas Blackwell Source Type: research
Inflammation, mitochondrial dysfunction and physical performance: a possible association in older patients with persistent atrial fibrillation-the results of a preliminary study
CONCLUSIONS: In older AF patients, IL-6 correlated with acylcarnitines and lower physical performance. Alterations in energy production, reduced physical function and inflammation could contribute to frailty development.PMID:37733227 | DOI:10.1007/s40520-023-02558-w
Source: Aging Clinical and Experimental Research - September 21, 2023 Category: Geriatrics Authors: Stefano Fumagalli Giulia Ricciardi Claudia Di Serio Giancarlo La Marca Giuseppe Pieraccini Riccardo Franci Montorzi Emanuele Santamaria Giulia Spanalatte Francesca Marchetti Ginevra Corti Laura Pinton Niccol ò Marchionni Source Type: research
Comparing Cardiovascular Outcomes and Costs of Perindopril-, Enalapril- or Losartan-Based Antihypertensive Regimens in South Africa: Real-World Medical Claims Database Analysis
CONCLUSION: In South African individuals with private health insurance, a perindopril-based antihypertensive regimen provided better clinical and cost outcomes compared with other regimens.PMID:37730949 | DOI:10.1007/s12325-023-02641-8
Source: Adv Data - September 21, 2023 Category: Epidemiology Authors: Jacques R Snyman Freedom Gumedze Erika S W Jones Olufunke A Alaba Nqoba Tsabedze Alykhan Vira Ntobeko A B Ntusi Source Type: research
AI diagnosis of heart sounds differentiated with super StethoScope
J Cardiol. 2023 Sep 19:S0914-5087(23)00229-0. doi: 10.1016/j.jjcc.2023.09.007. Online ahead of print.ABSTRACTIn the aging global society, heart failure and valvular heart diseases, including aortic stenosis, are affecting millions of people and healthcare systems worldwide. Although the number of effective treatment options has increased in recent years, the lack of effective screening methods is provoking continued high mortality and rehospitalization rates. Appropriately, auscultation has been the primary option for screening such patients, however, challenges arise due to the variability in auscultation skills, the obje...
Source: Journal of Cardiology - September 21, 2023 Category: Cardiology Authors: Shimpei Ogawa Fuminori Namino Tomoyo Mori Ginga Sato Toshitaka Yamakawa Shumpei Saito Source Type: research
Administration of Milrinone Following Tetralogy of Fallot Repair Increases Postoperative Volume Administration Without Improving Cardiac Output
CONCLUSIONS: The use of milrinone within the first 72 hours following TOF repair is associated with more frequent administration of volume, a positive association between a higher total dose of postoperative milrinone and the amount of postoperative volume administered, a higher heart rate, and a lower blood pressure, but is not associated with improved cardiac output.PMID:37733944 | DOI:10.1213/ANE.0000000000006662
Source: Anesthesia and Analgesia - September 21, 2023 Category: Anesthesiology Authors: Kwannapas Saengsin Francesca Sperotto Minmin Lu Julia Garcia Mancebo Elizabeth Sacco Manasee Godsay James A DiNardo John N Kheir Source Type: research
Revising the roles of aldosterone in vascular physiology and pathophysiology: from electocortin to baxdrostat
Can J Cardiol. 2023 Sep 19:S0828-282X(23)01732-4. doi: 10.1016/j.cjca.2023.08.035. Online ahead of print.ABSTRACTAldosterone was initially identified as a hormone primarily related to regulation of fluid and electrolyte homeostasis. However, over the past twenty years there has been an increasing appreciation of its role in regulation of vascular function and pathophysiology in the setting of hypertension, atherosclerosis, and heart failure. The purpose of this review is to highlight recent advances in our understanding the biology of aldosterone as it relates to the pathophysiology and the management of vascular disease-e...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Ross D Feldman Rohan Sanjanwala Raj Padwal Alexander A Leung Source Type: research
Testosterone Replacement Therapy and Cardiovascular Disease: Balancing Safety and Risks in Hypogonadal Men
Curr Cardiol Rep. 2023 Sep 21. doi: 10.1007/s11886-023-01935-1. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: The purpose of this review is to analyze the link between testosterone replacement therapy (TRT) and adverse cardiovascular (CV) events. RECENT FINDINGS: A few published studies suggest a link between TRT and CV events. These studies contained flaws, and many other studies reveal a reduction in CV events. Hypogonadism is associated with increased mortality in men with CVD. TRT in hypogonadal men can improve many CVD risk factors, reduce QT interval prolongation, lead to better outcomes in heart failure patients,...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Kelli Blackwell Michele Blackwell Thomas Blackwell Source Type: research
The characteristic large ‐scale annual analysis by gender and age in heart failure patients: cohort for 10 years in Korea
ConclusionsThe prevalence and incidence of HF are gradually increasing. It increased rapidly in their 50s and older. It showed an increased incidence of HF especially in men between their 50s and 70s, and more observation and caution for the management of the risk factors may be needed to prevent HF in the male group.
Source: ESC Heart Failure - September 21, 2023 Category: Cardiology Authors: Kyeong ‐Hyeon Chun,
Haeyong Pak,
Hyeongsoo Kim,
Ji‐Yong Jang,
Hancheol Lee,
Jong‐Kwan Park,
Seungjin Oh,
Se‐Jung Yoon Tags: Original Article Source Type: research
Noncardiac comorbidities and intensive up ‐titration of oral treatment in patients recently hospitalized for heart failure: insights from the STRONG‐HF trial
ConclusionsIn the STRONG-HF trial, non-cardiac comorbidities neither limited the rapid up-titration of HF-therapies, nor attenuated the benefit of HIC on primary endpoint.In the context of a clinical trial, the benefit-risk ratio favors the rapid up-titration of HF-therapies even in patients with multiple NCCsThis article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - September 21, 2023 Category: Cardiology Authors: Ovidiu Chioncel,
Beth Davison,
Marianna Adamo,
Laura E Antohi,
Mattia Arrigo,
Marianela Barros,
Jan Biegus,
Kamil ė Čerlinskaitė‐Bajorė,
Jelena Celutkiene,
Alain Cohen‐Solal,
Albertino Damasceno,
Rafael Diaz,
Christopher Edwards,
Gera Tags: Research Article Source Type: research
Stem cell-based therapies for heart failure management: a narrative review of current evidence and future perspectives
AbstractHeart failure (HF) is a prevalent and debilitating global cardiovascular condition affecting around 64 million individuals, placing significant strain on healthcare systems and diminishing patients ’ quality of life. The escalating prevalence of HF underscores the urgent need for innovative therapeutic approaches that target the root causes and aim to restore normal cardiac function. Stem cell-based therapies have emerged as promising candidates, representing a fundamental departure from con ventional treatments focused primarily on symptom management. This review explores the evolving landscape of stem cell-base...
Source: Heart Failure Reviews - September 21, 2023 Category: Cardiology Source Type: research
Estimated plasma volume status adds prognostic value to hemodynamic parameters in advanced heart failure
ConclusionePVS could additionally add prognostic value to hemodynamic parameters in advanced heart failure, although not correlated with hemodynamic parameters.Graphical Abstract
Source: Internal and Emergency Medicine - September 21, 2023 Category: Emergency Medicine Source Type: research
A Vascular Surgery Perspective on Baroreflex Activation Therapy
Baroreflex activation therapy is an emerging device-based treatment for patients suffering from heart failure with reduced ejection fraction (HFrEF) refractory to maximally tolerated goal-directed medical therapy. There is sparse literature on the critical role that vascular surgeons serve in the management of these challenging patients.
Source: Journal of Vascular Surgery - September 20, 2023 Category: Surgery Authors: Christopher Chow, Luanda Grazette, Omaida Velazquez, Tony Shao Tags: Other Source Type: research
