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Condition: Headache
Infectious Disease: SARS
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Total 172 results found since Jan 2013.
Pharmacotherapy for SARS-CoV-2 and Seizures for drug repurposing presumed on Mechanistic Targets
CONCLUSION: These findings would hopefully provide the basis for initiating further studies on the pathogenesis and drug targeting strategies for this emerging infection accompanied with seizures or in people with epilepsy.PMID:34645381 | DOI:10.2174/1874467214666211013122528
Source: Epilepsy Curr - October 14, 2021 Category: Neurology Authors: Divya Goel Ankit Srivastava Ángel Aledo-Serrano Anuja Krishnan Divya Vohora Source Type: research
Ischemic stroke revealing COVID-19 infection: Case report
CONCLUSION: SARS-COV 2 infection can spread from the respiratory system to the central nervous system, resulting in an inflammatory response and excessive secretion of inflammatory markers, leading to ischemic stroke.PMID:34631044 | PMC:PMC8492013 | DOI:10.1016/j.amsu.2021.102912
Source: Annals of Medicine - October 11, 2021 Category: Internal Medicine Authors: Alkouh Rajae Merbouh Manal El Aidouni Ghizlane Bouabdlaoui Amine None I Zaid Bkiyar Houssam Mabrouk Yassine Housni Brahim Source Type: research
Neuro ‐COVID‐19
AbstractNeuromuscular manifestations of new coronavirus infection (COVID-19) are frequent and include dizziness, headache, myopathy, and olfactory and gustatory disturbances. Patients with acute central nervous system (CNS) disorders, such as delirium, impaired consciousness, stroke, and convulsive seizures, have a high mortality rate. The encephalitis/encephalopathy that causes consciousness disturbance and seizures can be classified into three conditions, including direct infection with the SARS-CoV-2 virus, encephalopathy caused by CNS damage secondary to systemic hypercytokinemia (cytokine storm), and autoimmune-mediat...
Source: Clinical and Experimental Neuroimmunology - September 12, 2021 Category: Neurology Authors: Takayoshi Shimohata Tags: REVIEW ARTICLE Source Type: research
A mini-review on the impact of COVID 19 on vital organs
Biomed Pharmacother. 2021 Sep 4;143:112158. doi: 10.1016/j.biopha.2021.112158. Online ahead of print.ABSTRACTCOVID-19 (Corona Virus Disease-2019) is an infectious disease caused by a novel coronavirus, known as the acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This is a highly contagious disease that has already affected more than 220 countries globally, infecting more than 212 million people and resulting in the death of over 4.4 million people. This review aims to highlight the pertinent documentary evidence upon the adverse effects of the SARS-CoV-2 infection on several vital human organs. SARS-CoV-2 primarily ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 10, 2021 Category: Drugs & Pharmacology Authors: Muhammad Dawood Shah Aini Simon Sumeh Muhammad Sheraz Muthu Subash Kavitha Balu Alagar Venmathi Maran Kenneth Francis Rodrigues Source Type: research
Cerebrovascular Accident and SARS-CoV-19 (COVID-19): A Systematic Review
Discussion: The data suggest SARS-CoV-2 is a risk factor for developing stroke, particularly in patients with hypertension and diabetes. Furthermore, the younger average age of stroke in patients with SARS-CoV-2, particularly those patients with zero identifiable preexisting conditions, creates high suspicion that SARS-CoV-2 is an independent risk factor for development of stroke; however, this cannot yet be proven without comparable control population. The data suggest the risk of developing CVA in the setting of COVID-19 infection is not dependent upon severity of illness. Continued studies must be done to understand the...
Source: European Neurology - August 5, 2021 Category: Neurology Source Type: research
SARS-CoV-2 Poorly Replicates in Cells of the Human Blood-Brain Barrier Without Associated Deleterious Effects
Various neurological symptoms have been associated to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection including headache, fever, anosmia, ageusia, but also, encephalitis, Guillain-Barre syndrome and ischemic stroke. Responsible for the current coronavirus disease (COVID-19) pandemic, SARS-CoV-2 may access and affect the central nervous system (CNS) by several pathways such as axonal retrograde transport or through interaction with the blood-brain barrier (BBB) or blood-cerebrospinal fluid (CSF) barrier. Here, we explored the molecular and cellular effects of direct SARS-CoV-2 infection of human BBB c...
Source: Frontiers in Immunology - July 27, 2021 Category: Allergy & Immunology Source Type: research
Emerging neurotropic features of SARS-CoV-2
J Mol Cell Biol. 2021 Jul 21:mjab044. doi: 10.1093/jmcb/mjab044. Online ahead of print.ABSTRACTThe prevailing coronavirus disease (COVID-19) caused by a novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has presented some neurological manifestations including hyposmia, hypogeusia, headache, stroke, encephalitis, Guillain‒Barre syndrome, and some neuropsychiatric disorders. Although several cell types in the brain express angiotensin converting enzyme-2 (ACE2), the main SARS-CoV-2 receptor, and other related proteins, it remains unclear whether the observed neurological manifestations are attributed to viru...
Source: Mol Biol Cell - July 21, 2021 Category: Molecular Biology Authors: Wen-Rong Zhan Jing Huang Peng-Ming Zeng Wei-Ya Tian Zhen-Ge Luo Source Type: research
COVID-19 Has Numerous Neuropsychiatric Consequences, Report Finds
Anarticle appearing today in theJournal of Neuropsychiatry and Clinical Neurosciences provides a comprehensive overview of the neurological and psychiatric impact of the COVID-19 pandemic.“Although best known for its severe effects on respiratory function, SARS-CoV-2 produces a broad range of acute and chronic neurological and neuropsychiatric problems,” wrote Theodora Manolis, M.D., of Red Cross Hospital in Athens, Greece, and colleagues. “The COVID-19 pandemic has also had an important impact on the mental health of many individuals in the general population as a result of loss of loved ones, fear of calamity or de...
Source: Psychiatr News - July 20, 2021 Category: Psychiatry Tags: COVID-19 delirium depression headache hypoxia Journal of Neuropsychiatry and Clinical Neurosciences muscle pain neurological problems psychiatric problems psychosis stroke Source Type: research
Neurological manifestations of patients infected with the SARS-CoV-2: a systematic review of the literature
ConclusionThis updated review of literature, shows that headache, skeletal muscle injury, psychiatric disorders, impaired consciousness, and gustatory/olfactory dysfunction were the most common neurological symptoms of COVID-19 patients. Impaired consciousness and acute cerebrovascular events were significantly higher among patients with a severe infection. AIS patients required ICU admission in 63% of cases, while intra-hospital mortality rate was close to 23%.
Source: Journal of Neurology - July 19, 2021 Category: Neurology Source Type: research
COVID-19 and the Pediatric Nervous System: Global Collaboration to Meet a Global Need
AbstractThe coronavirus disease 2019 (COVID-19) pandemic has affected mortality and morbidity across all ages, including children. It is now known that neurological manifestations of COVID-19, ranging from headaches to stroke, may involve the central and/or peripheral nervous system at any age. Neurologic involvement is also noted in the multisystem inflammatory syndrome in children, a pediatric condition that occurs weeks after infection with the causative virus of COVID-19, severe acute respiratory syndrome coronavirus 2. Knowledge about mechanisms of neurologic disease is scarce but rapidly growing. COVID-19 neurologic ...
Source: Neurocritical Care - June 28, 2021 Category: Neurology Source Type: research
Focal cerebral arteriopathy in a young adult following SARS-CoV2 reinfection
Ten days after SARS-Cov2 reinfection with mild gastrointestinal symptoms and headache that occurred 2 months after an initial infection, a previously healthy 37-year-old woman developed fluctuating facial and upper limb paresthesia and weakness. Diffusion-weighted magnetic resonance imaging revealed ischemic lesions in the right parietal region of different stages within the same vascular territory. A cerebral angiography demonstrated an isolated focal arteriopathy with no other arterial involvement.
Source: Journal of Stroke and Cerebrovascular Diseases - June 12, 2021 Category: Neurology Authors: Carla Zanferrari, Simona Fanucchi, Maria Teresa Sollazzo, Michela Ranieri, Daniel Volterra, Luca Valvassori Source Type: research
SARS-CoV-2 Infection: Symptoms of the Nervous System and Implications for Therapy in Neurological Disorders
AbstractIn this paper, the neurological aspects of COVID-19 are presented, which may be of significance for physicians. Knowledge about the neurological symptoms of COVID-19 infection should help physicians in diagnoses and in taking appropriate precautions, as some manifestations can appear before typical pulmonary symptoms. Various mechanisms of SARS-CoV-2 neuroinvasion are discussed and symptoms are described, which can be subdivided into manifestations of the central nervous system (CNS) (headache, dizziness, stroke, impaired consciousness, encephalitis, meningitis, seizures) and peripheral nervous system (PNS) (charac...
Source: Neurology and Therapy - May 22, 2021 Category: Neurology Source Type: research
