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Association between Preexisting Sarcopenia and Stroke in Patients with Type 2 Diabetes Mellitus
ConclusionPreexisting sarcopenia increased the risk of stroke in patients with type 2 diabetes mellitus.
Source: The Journal of Nutrition, Health and Aging - September 14, 2022 Category: Nutrition Source Type: research

Major adverse cardiovascular and limb events in people with diabetes treated with GLP-1 receptor agonists vs SGLT2 inhibitors
Conclusions/interpretationIn people with diabetes, GLP1RA use was associated with significantly reduced risks of MALE compared with SGLT2i within the first 2 years after initiation, especially among people with diabetic neuropathy.Graphical abstract
Source: Diabetologia - August 9, 2022 Category: Endocrinology Source Type: research

IJERPH, Vol. 19, Pages 5118: Association of Postpartum Depression with Maternal Suicide: A Nationwide Population-Based Study
Conclusion: PPD was associated with a significantly higher rate of suicide and a shorter time to suicide after childbirth. Younger age, winter, and subclinical depression and anxiety positively predicted suicide in the study cohort. To prevent maternal suicide, clinicians should be observant of subclinical depression and anxiety symptoms among patients.
Source: International Journal of Environmental Research and Public Health - April 23, 2022 Category: Environmental Health Authors: Yi-Liang Lee Yun Tien Yin-Shiuan Bai Chi-Kang Lin Chang-Sheng Yin Chi-Hsiang Chung Chien-An Sun Shi-Hao Huang Yao-Ching Huang Wu-Chien Chien Chieh-Yi Kang Gwo-Jang Wu Tags: Article Source Type: research

PPAR agonists for the treatment of cardiovascular disease in patients with Diabetes
Conclusions: According to this study, Pioglitazone treatment in type 2 diabetes patients and hypersensitive Ischemic stroke patients is linked to minor ischemic stroke which is recurrent in Asian people. Pioglitazone and the telmisartan treatment have an increasing pleiotropic effect related to the higher PPAR- gamma effects. Further research needs to be conducted with the PPAR mechanism ' s details to confirm the PPAR effect on Ischemic stroke treatment. [Ethiop. J. Health Dev. 2021; 35(3): 249-257]Keywords: PPAR agonist, Dyslipidaemia, Thiazolidinediones, Type 2 diabetes, Pioglitazone, PPAR-alpha, PPAR-gamma, Insulin resistance, Alecardio.
Source: Ethiopian Journal of Health Development - November 25, 2021 Category: African Health Authors: Zheng Xia, Guo Lixia, Zhang Zhijun Source Type: research

Major adverse cardiovascular and limb events in patients with diabetes treated with GLP-1 receptor agonists vs DPP-4 inhibitors
Conclusions/interpretationIn individuals with diabetes, the use of GLP1RAs was associated with significantly lower risks of major adverse limb events when compared with the use of DPP4is. The reduction in risk was driven largely by reduced rate of amputations. Moreover, treatment with GLP1RAs was also associated with lower risks of cardiovascular death, non-fatal stroke, non-fatal myocardial infarction and death from any cause. However, some unexplored confounding factors may exist in this observation study and future large-scale randomised controlled trials are needed.Graphical abstract
Source: Diabetologia - August 24, 2021 Category: Endocrinology Source Type: research

Telmisartan use and risk of dementia in type 2 diabetes patients with hypertension: A population-based cohort study
by Chi-Hung Liu, Pi-Shan Sung, Yan-Rong Li, Wen-Kuan Huang, Tay-Wey Lee, Chin-Chang Huang, Tsong-Hai Lee, Tien-Hsing Chen, Yi-Chia Wei BackgroundAngiotensin receptor blockers (ARBs) may have protective effects against dementia occurrence in patients with hypertension (HTN). However, whether telmisartan, an ARB with peroxisome proliferator-activated receptor γ (PPAR-γ)–modulating effects, has additional benefits compared to other ARBs remains unclear. Methods and findingsBetween 1997 and 2013, 2,166,944 type 2 diabetes mellitus (T2DM) patients were identified from the National Health Insurance Research Database of Taiwa...
Source: PLoS Medicine - July 19, 2021 Category: Internal Medicine Authors: Chi-Hung Liu Source Type: research

IJERPH, Vol. 17, Pages 8549: Migraine as a Risk Factor for Peripheral Artery Occlusive Disease: A Population-Based Cohort Study
In conclusion, the presence of migraine is a significant risk factor for the development of subsequent PAOD.
Source: International Journal of Environmental Research and Public Health - November 18, 2020 Category: Environmental Health Authors: Fu-Hsuan Kuo Chia-Yi Lee Ju-Pi Li Jui-Fu Chung Yu-Hsun Wang Ming-Ju Hsieh Shun-Fa Yang Tags: Article Source Type: research

Oral Anticoagulants and Antiplatelet Agents in Atrial Fibrillation Patients with Concomitant Critical Limb Ischemia: A nationwide cohort study
ConclusionsDOAC was associated with a significantly lower risk of composite net-clinical-benefit outcome than either warfarin or APT in AF patients with concomitant CLI. Further prospective study is necessary to validate the findings in the future.
Source: Canadian Journal of Cardiology - February 19, 2020 Category: Cardiology Source Type: research

Predicting the Risk of Ischemic Stroke among Patients with Rheumatoid Arthritis Using a Simplified RA-CHADSV Score Based on the CHA2DS2-VASc Score.
CONCLUSIONS: A simplified RA-CHADSV score, with comparable efficiency as the CHA2DS2-VASc score, but easier to use clinically was developed for predicting the risk of ischemic stroke among non-AF RA patients. PMID: 32059458 [PubMed - in process]
Source: Medicina (Kaunas) - February 11, 2020 Category: Universities & Medical Training Authors: Hsu CW, Ng KJ, Lu MC, Koo M Tags: Medicina (Kaunas) Source Type: research

Association of obstructive sleep apnea with female infertility - A 13-year nationwide population-based retrospective study
Conclusions: Our study provides a nationwide, population based, 13-year retrospective data demonstrating that OSA patients are at a higher risk of female infertility.Keywords: Obstructive sleep apnea; Female infertility; Taiwan National Health Insurance Research Database; Longitudinal Health Insurance Database
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Wang, I.-D., Tsai, P.-Y., Peng, C.-K., Chung, C.-H., Liu, F.-C., Chang, S.-Y., Chien, W.-C. Tags: Sleep and control of breathing Source Type: research

Late Breaking Abstract - Economics burden and healthcare utilization in chronic obstructive pulmonary disease patients with or without sepsis
Conclusions: COPD patients who encountered sepsis were associated with higher economics burden and healthcare utilization.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Chen, Y., Wu, H.-F., Fang, W.-F., Chen, H.-C., Lin, C.-Y., Lin, M.-C. Tags: Ethics and economics Source Type: research

IJERPH, Vol. 16, Pages 3831: Incidence of Cellulitis Following Acupuncture Treatments in Taiwan
Conclusions: A variety of chronic diseases may increase the risk of cellulitis after acupuncture. Physicians asked about past medical history before acupuncture might help to reduce cellulitis.
Source: International Journal of Environmental Research and Public Health - October 10, 2019 Category: Environmental Health Authors: Shun-Ku Lin Jui-Ming Liu Pin-Hsuan Wang Sheng-Ping Hung Ren-Jun Hsu Heng-Chang Chuang Po-Hung Lin Tags: Article Source Type: research

Prevalence of diabetic macrovascular complications and related factors from 2005 to 2014 in Taiwan: A nationwide survey
ConclusionFrom this nationwide study, we observed a decrease in the prevalence of diabetic macrovascular complications, such as stroke, CVD, and HF, but an increase in the prevalence of PVDs in the past decade in Taiwan.
Source: Journal of the Formosan Medical Association - September 19, 2019 Category: General Medicine Source Type: research

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