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IJERPH, Vol. 15, Pages 25: Endocrine Disrupting Chemicals Mediated through Binding Androgen Receptor Are Associated with Diabetes Mellitus
Huixiao Hong Endocrine disrupting chemicals (EDCs) can mimic natural hormone to interact with receptors in the endocrine system and thus disrupt the functions of the endocrine system, raising concerns on the public health. In addition to disruption of the endocrine system, some EDCs have been found associated with many diseases such as breast cancer, prostate cancer, infertility, asthma, stroke, Alzheimer’s disease, obesity, and diabetes mellitus. EDCs that binding androgen receptor have been reported associated with diabetes mellitus in in vitro, animal, and clinical studies. In this review, we summarize the struct...
Source: International Journal of Environmental Research and Public Health - December 23, 2017 Category: Environmental Health Authors: Sugunadevi Sakkiah Tony Wang Wen Zou Yuping Wang Bohu Pan Weida Tong Huixiao Hong Tags: Review Source Type: research

Mortality of Shift Workers
This study strengthens the evidence of a connection between shift work and all-cause mortality. It also provides support for an association between shift work and mortality of cardiovascular disease. The mechanisms responsible for the association between shift work and disease are probably co mplex and influenced by genetics, lifestyle, sleep, social stress, and disturbed circadian rhythms (7). Further epidemiological studies and experimental studies are needed to explain the causal pathways. One issue would be to find a better variable measuring the circadian phase. Shift work is not a valid proxy since previous studies...
Source: Scandinavian Journal of Work, Environment and Health - January 25, 2017 Category: Occupational Health Tags: Editorial Source Type: research

Nine Easy Ways to Gain Control of Your Health in Your Forties
What lifestyle changes should you make to stay healthy through your 40s? originally appeared on Quora - the knowledge sharing network where compelling questions are answered by people with unique insights. Answer by Keck Medicine of USC, 500+ internationally renowned doctors at a leading academic medical center, on Quora: Getting older has its perks. Chances are you're more confident, have more direction and a defined sense of self. While your health is likely not a primary concern, it's important to take steps now to stop subtle changes before they become major health issues. Your 40s is the decade that your habits sta...
Source: Healthy Living - The Huffington Post - January 9, 2017 Category: Consumer Health News Source Type: news

Behind the Headlines 2016 Quiz of the Year
In 2014, Behind the Headlines has covered more than 500 health stories that made it into the mainstream media. If you've been paying attention you should find this quiz easy and fun. Why not test your knowledge of 2014's health news with our month-by-month quiz? Answers are at the foot of the page (no peeking!).   In January 2016's health news... In a controversial study, monkeys were genetically engineered to develop what disorder? 1) Sex addiction 2) Bi-polar disorder 3) Autism In a similarly controversial study, what psychological condition was dismissed as a "myth" 1) Seasonal affective disorder...
Source: NHS News Feed - December 5, 2016 Category: Consumer Health News Tags: Special reports Source Type: news

Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence.
CONCLUSION: The totality of available scientific evidence supports that intake of milk and dairy products contribute to meet nutrient recommendations, and may protect against the most prevalent chronic diseases, whereas very few adverse effects have been reported. PMID: 27882862 [PubMed - in process]
Source: Food and Nutrition Research - November 26, 2016 Category: Nutrition Authors: Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A Tags: Food Nutr Res Source Type: research

Expensive New Diabetes Drugs Add Nothing But Cost And Complications
This is the fourth in an ongoing series of blogs exposing the rampant misuse of the medications so aggressively promoted by greedy drug companies. I am very lucky in having the perfect partner in this truth-vs-power effort to contradict Pharma propaganda with evidence based fact. Dick Bijl is President of the International Society of Drug Bulletins (ISDB), an impressive association of 53 national drug bulletins from all around the world, each of which publishes the best available data on the pluses and minuses of different medications. Drug bulletins help patients and doctors see through the misleading misinformation ge...
Source: Science - The Huffington Post - November 17, 2016 Category: Science Source Type: news

A Perfect Match: health, Hippocrates and lifestyle medicine
Amid the frustration and despair associated with rising premiums, healthcare costs and obesity prevalence, is a trend that is slowly infiltrating the healthcare industry. Although some of the most notable trends (in fitness and nutrition) tend to come and go as quickly as a fastball (World Series, anyone?), this particular trend has an immense amount of staying power based on current scientific research. This immense power has little to do with pharmacological interventions and prescription refills and much more to do with our feet, forks, fingers and minds. This trend, as written in a recent article by the influential and...
Source: Healthy Living - The Huffington Post - November 3, 2016 Category: Consumer Health News Source Type: news

Lifestyle factors and prostate-specific antigen (PSA) testing in UK Biobank: Implications for epidemiological research
Conclusions A variety of sociodemographic, lifestyle and health-related characteristics are associated with PSA testing, suggesting that observed associations of some of these traits with risk for prostate cancer in epidemiological studies may be, at least partially, due to detection bias.
Source: Cancer Epidemiology - September 29, 2016 Category: Cancer & Oncology Source Type: research

Potential health hazards of eating red meat
Abstract Red meat (beef, veal, pork, lamb and mutton) consumption contributes several important nutrients to the diet, for example essential amino acids, vitamins (including B12) and minerals (including iron and zinc). Processed red meat (ham, sausages, bacon, frankfurters, salami, etc.) undergoes treatment (curing, smoking, salting or the use of chemical preservatives and additives) to improve its shelf life and/or taste. During recent decades, consumption of red meat has been increasing globally, especially in developing countries. At the same time, there has been growing evidence that high consumption of red meat, espec...
Source: Journal of Internal Medicine - August 31, 2016 Category: Internal Medicine Authors: A. Wolk Tags: Review Source Type: research

Prostate size, nocturia and the digital rectal examination: a cohort study of 30 500 men
ConclusionsDigital rectal examination is a modestly accurate tool for measuring prostate volume. While DRE posterior surface area represents a statistically significant predictor of nocturia, the magnitude of effect suggests it has limited clinical utility for assessing this condition, particularly in the presence of cardiovascular risk factors.
Source: BJU International - August 22, 2016 Category: Urology & Nephrology Authors: Benjamin V. Stone, Jonathan Shoag, Joshua A. Halpern, Sameer Mittal, Patrick Lewicki, David M. Golombos, Dina Bedretdinova, Bilal Chughtai, Christopher E. Barbieri, Richard K. Lee Tags: Original Article Source Type: research

Safety of long-term exposure to abiraterone acetate in patients with castration-resistant prostate cancer and concomitant cardiovascular risk factors
Conclusions: Long-term abiraterone treatment was well tolerated in mCRPC patients with controlled cardiovascular comorbidities/risk factors, with no apparent worsening of cardiovascular conditions from baseline over an extended observation period.
Source: Therapeutic Advances in Medical Oncology - August 7, 2016 Category: Cancer & Oncology Authors: Verzoni, E., Grassi, P., Ratta, R., Niger, M., De Braud, F., Valdagni, R., Procopio, G. Tags: Original Research Source Type: research

Prostate size, nocturia, and the digital rectal exam: a cohort study of 30,500 men
ConclusionsDRE is a modestly accurate tool for measuring prostate volume. While DRE posterior surface area represents a statistically significant predictor of nocturia, the magnitude of effect suggests it has limited clinical utility for assessing this condition, particularly in the presence of cardiovascular risk factors.This article is protected by copyright. All rights reserved.
Source: BJU International - July 31, 2016 Category: Urology & Nephrology Authors: Benjamin V. Stone, Jonathan Shoag, Joshua A. Halpern, Sameer Mittal, Patrick Lewicki, David M. Golombos, Dina Bedretdinova, Bilal Chughtai, Christopher E. Barbieri, Richard K. Lee Tags: Original Article Source Type: research

EPMA-World Congress 2015
Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of ...
Source: EPMA Journal - May 8, 2016 Category: Global & Universal Source Type: research

Survival and cardiovascular events in men treated with testosterone replacement therapy: an intention-to-treat observational cohort study
Publication date: Available online 7 May 2016 Source:The Lancet Diabetes & Endocrinology Author(s): Christopher J D Wallis, Kirk Lo, Yuna Lee, Yonah Krakowsky, Alaina Garbens, Raj Satkunasivam, Sender Herschorn, Ronald T Kodama, Patrick Cheung, Steven A Narod, Robert K Nam Background Conflicting evidence exists for the association between testosterone replacement therapy and mortality and cardiovascular events. The US Food and Drug Administration recently cautioned that testosterone replacement therapy might increase risk of heart attack and stroke, based on evidence from studies with short treatment d...
Source: The Lancet Diabetes and Endocrinology - May 7, 2016 Category: Endocrinology Source Type: research

Emerging trends in non-communicable disease mortality in South Africa, 1997 - 2010.
CONCLUSIONS: NCDs contribute to premature mortality in SA, threatening socioeconomic development. While NCD mortality rates have decreased slightly, it is necessary to strengthen prevention and healthcare provision and monitor emerging trends in cause-specific mortality to inform these strategies if the target of 2% annual decline is to be achieved. PMID: 27138667 [PubMed - as supplied by publisher]
Source: South African Medical Journal - May 5, 2016 Category: African Health Tags: S Afr Med J Source Type: research

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