Bone sarcoma incidence in the Netherlands
ConclusionsThis study provides comprehensive incidence estimates for all the main primary bone sarcomas over a 15-year time period in a Northern European country with little migration. Centralisation of bone sarcoma care improves the clinical outcome in osteosarcoma. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 22, 2019 Category: Cancer & Oncology Source Type: research

Rational targeting of population groups and residential areas for colorectal cancer screening
ConclusionsOur analytic approach provided rational support for targeted intervention when implementing CRC screening, aiming at optimizing participation in groups with low educational level. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 20, 2019 Category: Cancer & Oncology Source Type: research

Initial management of meningiomas: Analysis of the National Cancer Database
ConclusionsOver half of patients were diagnosed by imaging, suggesting a higher role of clinical determinants over histological confirmation in treatment decisions. Watchful waiting as initial management is increasing. Our survival analysis favored histological confirmation. Patients receiving radiation and surgery had an increased risk of mortality. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 16, 2019 Category: Cancer & Oncology Source Type: research

Associations of serum CRP levels with demographics, health behaviors, and risk of cancer among the Mexican American Mano A Mano Cohort
Publication date: June 2019Source: Cancer Epidemiology, Volume 60Author(s): Jie Shen, Daphne Hernandez, Lorna Haughton McNeill, Wong-Ho Chow, Hua ZhaoAbstractC-Reactive protein (CRP) is a well-known inflammatory marker, and elevated CRP levels has been reported to be associated with the risk of various cancers. To date, no study has investigated the association between elevated CRP and incidents of cancer among Mexican Americans. In the current prospective cohort study, we measured pre-diagnostic CRP levels in serum samples and evaluated their relationships with demographic characteristics and health behaviors associated w...
Source: Cancer Epidemiology - March 16, 2019 Category: Cancer & Oncology Source Type: research

Future of cancer incidence in Shanghai, China: Predicting the burden upon the ageing population
Publication date: June 2019Source: Cancer Epidemiology, Volume 60Author(s): Zhenqiu Liu, Yanfeng Jiang, Qiwen Fang, Huangbo Yuan, Ning Cai, Chen Suo, Weimin Ye, Xingdong Chen, Tiejun ZhangAbstractAimThe age-specific cancer patterns have changed significantly over the last few decades in urban Shanghai. Predicting the cancer incidence in an ageing population can help to anticipate future resource needs, evaluate primary prevention strategies, and inform further research studies.Materials and MethodsAnnual cancer cases and population data from 1988 to 2013 were collected from Shanghai Cancer Registry. A Bayesian age-period-c...
Source: Cancer Epidemiology - March 16, 2019 Category: Cancer & Oncology Source Type: research

Soft tissue sarcoma in Italy: From epidemiological data to clinical networking to improve patient care and outcomes
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Annalisa Trama, Giuseppe Badalamenti, Giacomo Giulio Baldi, Antonella Brunello, Morena Caira, Nora Drove, Andrea Marrari, Emanuela Palmerini, Bruno Vincenzi, Angelo Paolo Dei Tos, Giovanni GrignaniAbstractSarcomas are rare malignant neoplasms that develop from mesenchymal cells and include a heterogeneous and large group of histological subtypes that may occur at any anatomical site. Soft tissue sarcomas (STS), the focus of this review, account for ≈70‒80% of sarcomas and represent
Source: Cancer Epidemiology - March 12, 2019 Category: Cancer & Oncology Source Type: research

Causes of death in men with prostate cancer: Results from the Danish Prostate Cancer Registry (DAPROCAdata)
ConclusionsMore than half of the deceased men in our study cohort died of their prostate cancer disease within a mean of 2.4 years of follow up. Data from the death registry is prone to misclassification, potentially overestimating the proportion of deaths from prostate cancer. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 10, 2019 Category: Cancer & Oncology Source Type: research

Wait times to diagnosis and treatment in patients with colorectal cancer in Hungary
ConclusionsWait times to diagnosis and treatment of CRC in Hungary are similar to Western countries however the ratio of advanced cancers at diagnosis is higher. The cause of late diagnosis may be due to patient delay, indicating the need for implementation of primary and secondary prevention. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 6, 2019 Category: Cancer & Oncology Source Type: research

The impact of rheumatological disorders on lymphomas and myeloma: a report on risk and survival from the UK’s population-based Haematological Malignancy Research Network
ConclusionOur findings support the hypothesis that the chronic activation and proliferation of specific B-cell populations which characterize autoimmune disease increase the potential for the lymphomagenic events that lead to DLBCL and MZL in both males and females; but have no impact on the development of CLL, FL or MM, or on survival. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 5, 2019 Category: Cancer & Oncology Source Type: research

The future burden of cancer in Canada: Long-term cancer incidence projections 2013–2042
ConclusionThese cancer incidence projections up to 2042 can be used for planning cancer control strategies and prevention programs. Given the ongoing changes in the prevalence of risk factors and in cancer prevention policies, these estimates should be interpreted with caution. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 4, 2019 Category: Cancer & Oncology Source Type: research

Stage at diagnosis for childhood solid cancers in Australia: A population-based study
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Danny R. Youlden, A. Lindsay Frazier, Sumit Gupta, Kathy Pritchard-Jones, Maria L. Kirby, Peter D. Baade, Adèle C. Green, Patricia C. Valery, Joanne F. AitkenAbstractBackgroundStage of cancer at diagnosis is one of the strongest predictors of survival and is essential for population cancer surveillance, comparison of cancer outcomes and to guide national cancer control strategies. Our aim was to describe, for the first time, the distribution of cases by stage at diagnosis and differences in stage-specific survival on a population basis for ...
Source: Cancer Epidemiology - March 4, 2019 Category: Cancer & Oncology Source Type: research

Distribution of multiple myeloma in India: Heterogeneity in incidence across age, sex and geography
ConclusionIncidence of MM in India is presented. Marked variations in MM incidence were noted with respect to age, sex and geography. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 4, 2019 Category: Cancer & Oncology Source Type: research

Declining hysterectomy prevalence and the estimated impact on uterine cancer incidence in Scotland
ConclusionUterine cancer incidence in Scotland corrected for hysterectomy prevalence is higher than estimates using a total female population as denominator. The annual percentage increase in uterine cancer incidence was stable in both uncorrected and corrected populations despite a declining hysterectomy prevalence. The rise in uterine cancer incidence may thus be driven by other factors, including an ageing population, changing reproductive choices, and obesity. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - March 4, 2019 Category: Cancer & Oncology Source Type: research

Partial nephrectomy vs cryoablation for T1a renal cell carcinoma: A comparison of survival benefit stratified by tumour size
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Xinyang Liao, Shi Qiu, Wanyu Wang, Xiaonan Zheng, Kun Jin, Shiyu Zhang, Yige Bao, Lu Yang, Qiang WeiAbstractObjectiveWe compared the impact on survival outcomes of partial nephrectomy (PN) and cryoablation (CA) for patients diagnosed with T1a renal cell carcinoma (RCC).Patients and MethodsAmong patients diagnosed between 2004 and 2014 in the Surveillance, Epidemiology and End Results program, we identified histologically confirmed T1aN0M0 RCC treated with PN (n = 17644) or CA (n = 868). Propensity score matching (PSM) was performed. Kaplan-Meier m...
Source: Cancer Epidemiology - March 4, 2019 Category: Cancer & Oncology Source Type: research

Improving the reporting of cancer-specific mortality and survival in research using cancer registry data
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Michel D. Wissing, Zoë R. Greenwald, Eduardo L. FrancoAbstractPopulation-based registries are increasingly used in cancer research. In such studies, cancer-specific mortality or survival is frequently used as the primary outcome. To determine whether a putative cancer was part of the causal chain of events leading to death, cancer registries primarily rely on death certificates. Hence, they depend on the subjective interpretation of information available to medical examiners at the time of death. Misclassification may occur: studies report mi...
Source: Cancer Epidemiology - March 4, 2019 Category: Cancer & Oncology Source Type: research

Trends in regional cancer mortality in Taiwan 1992–2014
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Yu Rong Ho, Shang-Pin Ma, Kuan Y. ChangAbstractBackgroundAlthough the cancer mortality rate in Taiwan has been declining in recent years, no study has yet reported any regional differences in cancer mortality rates in Taiwan. We hypothesized that regional cancer mortality rates in Taiwan, an ethnically homogeneous society, exhibited no significant variations.MethodsWe investigated the trends in Taiwan regional cancer mortality between 1992 and 2014. We analyzed regional age-standardized cancer mortality rates for lung, liver, colon, stomach, oral,...
Source: Cancer Epidemiology - March 1, 2019 Category: Cancer & Oncology Source Type: research

Long-term survival of patients with prostate cancer in Martinique: Results of a population-based study
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Clarisse Joachim, Stephen Ulric-Gervaise, Moustapha Dramé, Jonathan Macni, Patrick Escarmant, Jacqueline Véronique-Baudin, Vincent Vinh-HungAbstractBackgroundMartinique has one of the highest incidences of prostate cancer (PCa) worldwide. We analysed overall survival (OS) among patients with PCa in Martinique, using data from a population-based cancer registry between 2005 and 2014.MethodsThe log-rank test was used to assess the statistical differences between survival curves according to age at diagnosis, risk of disease progression...
Source: Cancer Epidemiology - March 1, 2019 Category: Cancer & Oncology Source Type: research

Perinatal and early life risk factors for childhood brain tumors: Is instrument-assisted delivery associated with higher risk?
ConclusionsPerinatal and early-life risk factors, and specifically indicators of brain trauma, exposure to toxic agents and immune system maturation, might be involved in the pathogenesis of childhood brain tumors. Larger studies should aim to replicate our findings and examine associations with tumor subtypes. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 27, 2019 Category: Cancer & Oncology Source Type: research

Involuntary smoking and the risk of head and neck cancer in an East Asian population
ConclusionsOur study supports the association between involuntary smoking and the risk of HNC. The association may be stronger for oral cavity cancer than for other HNC subsites. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 20, 2019 Category: Cancer & Oncology Source Type: research

Parental age and the risk of childhood acute myeloid leukemia: results from the Childhood Leukemia International Consortium
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Paraskevi Panagopoulou, Alkistis Skalkidou, Erin Marcotte, Friederike Erdmann, Xiaomei Ma, Julia E. Heck, Anssi Auvinen, Beth A. Mueller, Logan G. Spector, Eve Roman, Catherine Metayer, Corrado Magnani, Maria S. Pombo-de-Oliveira, Michael E. Scheurer, Ana-Maria Mora, John D. Dockerty, Johnni Hansen, Alice Y. Kang, Rong Wang, David R. DoodyAbstractBackgroundParental age has been associated with several childhood cancers, albeit the evidence is still inconsistent.AimTo examine the associations of parental age at birth with acute myeloid leukemia (AM...
Source: Cancer Epidemiology - February 16, 2019 Category: Cancer & Oncology Source Type: research

A pilot study on clinicopathological features and intestinal microflora changes in colorectal cancer patients born over a nine-year period encompassing three years before and after the Great Chinese famine
ConclusionsLimitation of energy intake during childhood may affect the composition of gut microbiota, resulting in persistent epigenetic changes that subsequently influence the prognosis of patients with CRC. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 16, 2019 Category: Cancer & Oncology Source Type: research

Proportion of cancer cases and deaths attributable to lifestyle risk factors in Brazil
ConclusionFindings from this study may be useful to inform strategies for cancer prevention and control across Brazil. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 15, 2019 Category: Cancer & Oncology Source Type: research

Contemporary trends of pelvic lymph node dissection at radical cystectomy for urothelial carcinoma of urinary bladder and associated cancer specific mortality and complications: comparison between octogenarian versus younger patients
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Francesco A. Mistretta, Elio Mazzone, Sophie Knipper, Carlotta Palumbo, Zhe Tian, Sebastiano Nazzani, Fred Saad, Emanuele Montanari, Derya Tilki, Alberto Briganti, Shahrokh F. Shariat, Ottavio de Cobelli, Pierre I. KarakiewiczAbstractBackgroundWe analysed contemporary pelvic lymph node dissection (PLND) trend during radical cystectomy (RC) for urothelial carcinoma of urinary bladder (UCUB), as well as PLND association with cancer specific mortality (CSM) and complications after stratification according to octogenarian vs. younger age.Materials and...
Source: Cancer Epidemiology - February 14, 2019 Category: Cancer & Oncology Source Type: research

Temporal and geographical variations in colorectal cancer incidence in Northern Iran 2004–2013
Conclusions: CRC incidence rates in Golestan have been rising during the most recent decade, with a higher incidence and more rapid increases among men and the urban populations. The underlying risk factors should be assessed in the context of developing CRC prevention interventions in Golestan. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 14, 2019 Category: Cancer & Oncology Source Type: research

Evaluation of p16/Ki-67 dual staining in the detection of cervical precancer and cancer in China
Conclusion P16/Ki-67 dual staining could probably provide an optional method for China’s national cervical cancer screening, and could also be considered as an efficient method of triage for managing women with ASC-US. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 10, 2019 Category: Cancer & Oncology Source Type: research

A validated algorithm for register-based identification of patients with recurrence of breast cancer—Based on Danish Breast Cancer Group (DBCG) data
Conclusion: The developed algorithm almost perfectly identified BC recurrence and with reasonable timing compared to the gold standard. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 10, 2019 Category: Cancer & Oncology Source Type: research

Cancer diagnostic delays and travel distance to health services: A nationwide cohort study in Denmark
ConclusionTravel distance to cancer diagnostic health care services was associated with interval length in the diagnostic pathway. This association was less pronounced in the period after introducing CPPs and also strongly depending of the underlying cancer type and symptomatology. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 8, 2019 Category: Cancer & Oncology Source Type: research

A missense variant in PTPN12 associated with the risk of colorectal cancer by modifying Ras/MEK/ERK signaling
ConclusionOur study highlights that PTPN12 rs3750050 could increase CRC risk by modifying Ras/MEK/ERK signaling. This work provides a novel insight into the roles of genetic variants within PTP genes in the pathogenesis of CRC. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 6, 2019 Category: Cancer & Oncology Source Type: research

Insurance status as a modifier of the association between race and stage of prostate cancer diagnosis in Florida during 1995 and 2013
Conclusion: Insurance status may modify the effect of race on late stage prostate cancer in black patients. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - February 5, 2019 Category: Cancer & Oncology Source Type: research

The burden of cervical cancer in Vietnam: Synthesis of the evidence
This study aims to synthesize available data on the burden of disease and to project the burden of cervical cancer to 2049 if no major interventions are implemented. We reviewed published data sources on risk factors for HPV prevalence, high-grade lesions, cervical cancer incidence and mortality in Vietnam from 1990 to 2017. We then used the available data to project the number of new cervical cancer cases for the period 2013–2049. Data on cervical cancer incidence and mortality in Vietnam are limited; two Vietnamese cancer registries have been reported on by the International Agency for Research on Cancer, which cov...
Source: Cancer Epidemiology - January 31, 2019 Category: Cancer & Oncology Source Type: research

Is pleural infection associated with longer survival in mesothelioma? A population-based cohort study using data from Hospital Episode Statistics
ConclusionPleural infection occurred in 2.3% of people with mesothelioma and was associated with shorter survival. This refutes previous reports suggesting pleural infection may be associated with better outcomes in thoracic malignancy. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 31, 2019 Category: Cancer & Oncology Source Type: research

Pilot study of DNA methylation-derived neutrophil-to-lymphocyte ratio and survival in pediatric medulloblastoma
DiscussionFuture work is warranted to investigate the relationship between mdNLR outcomes in specific pediatric medulloblastoma molecular subgroups. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 30, 2019 Category: Cancer & Oncology Source Type: research

Title page / Editorial Board
Publication date: February 2019Source: Cancer Epidemiology, Volume 58Author(s): (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 29, 2019 Category: Cancer & Oncology Source Type: research

Table of contents
Publication date: February 2019Source: Cancer Epidemiology, Volume 58Author(s): (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 29, 2019 Category: Cancer & Oncology Source Type: research

Bias in survival estimates created by a requirement for consent to enter a clinical breast cancer registry
ConclusionData from a registry requiring active consent gives an upward bias in survival results, as non-consenting patients have more extensive disease, less treatment, and lower survival. To give unbiased results active consent should be not required in a clinical cancer registry. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 29, 2019 Category: Cancer & Oncology Source Type: research

Impact of variation in cancer registration practice on observed international cancer survival differences between International Cancer Benchmarking Partnership (ICBP) jurisdictions
ConclusionPopulation-based cancer survival comparisons can be subject to registration biases that may impact the reported ‘survival gap’ between populations. Efforts should be made to apply consistent registration practices internationally. In the meantime, survival comparison studies should provide acknowledgement of or adjustment for the registration biases that may affect their conclusions. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 29, 2019 Category: Cancer & Oncology Source Type: research

Risk of mycobacterial disease among cancer patients: A population-based cohort study in a TB endemic area
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Yi-Ming Chen, Ching-Heng Lin, Hsin-Hua Chen, Wen-Cheng Chao, Der-Yuan Chen, Che-Chen Lin, Tsai-Ling LiaoAbstractObjectivesTuberculosis (TB) and nontuberculous mycobacteria (NTM) disease have similar symptoms, which makes them difficult to distinguish clinically and leads to the danger of NTM disease being neglected. The aim of this study was to assess the risk of developing mycobacterial disease among cancer patients.MethodsWe conducted a retrospective cohort study using a population-based database. The multivariable Cox proportional hazards model...
Source: Cancer Epidemiology - January 29, 2019 Category: Cancer & Oncology Source Type: research

Aerobic fitness in late adolescence and the risk of cancer and cancer-associated mortality in adulthood: A prospective nationwide study of 1.2 million Swedish men
ConclusionsThese findings identify in late adolescence a potentially modifiable predictor of cancer, with higher aerobic fitness associated with a decreased risk of cancer incidence and mortality later in life. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 27, 2019 Category: Cancer & Oncology Source Type: research

Trends of incidence and survival of patients with chronic myelomonocytic leukemia between 1999 and 2014: A comparison between Swiss and American population-based cancer registries
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Sonia Benzarti, Michael Daskalakis, Anita Feller, Vera Ulrike Bacher, Annatina Schnegg-Kaufmann, Axel Rüfer, Andreas Holbro, Adrian Schmidt, Rudolf Benz, Max Solenthaler, Georg Stussi, Volker Arndt, Nicolas Bonadies, the NICER Working GroupAbstractBackgroundChronic myelomonocytic leukemia (CMML) is a rare hematopoietic malignancy. Treatment with hypomethylating agents (HMA) was introduced between 2004 and 2006 but its impact on population-based survival remains controversial. The aim of this study was to investigate epidemiological characteri...
Source: Cancer Epidemiology - January 26, 2019 Category: Cancer & Oncology Source Type: research

Cancer incidence in Cotonou (Benin), 2014–2016: First results from the cancer Registry of Cotonou
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Marcel Egue, Freddy H.R. Gnangnon, Marie-Thérèse Akele-Akpo, D. Maxwell ParkinAbstractIncidence data from the population cancer registry of Cotonou (Benin) for the three year period 2014–2016 are presented.1086 cancer cases were recorded, 608 cases (56.0%) in women (corresponding to an age standardized incidence rate (ASR) of 78.4 per 100,000) and 478 cases (44.0%) in men (ASR 91.8 per 100,000).Breast and cervical cancer accounted for 49.2% of all cancers in women. Breast cancer (ASR 22.6 per 100,000) was more common than cervi...
Source: Cancer Epidemiology - January 25, 2019 Category: Cancer & Oncology Source Type: research

Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK
This study sought to improve understanding of the intervals from first symptom recognition to diagnosis for HNC and investigate associations between patient-reported symptoms and socio-demographic factors.MethodsPeople within 3 months of diagnosis, completed a researcher-administered questionnaire and data were extracted from primary and secondary care clinical records.ResultsEighty (mean age 62.9 [SD 11.7] years; 66% men) were interviewed. The appraisal interval was longer than a month for 39% of participants and the help-seeking interval was longer than a week for 44%. The median diagnostic interval was 92 (IQR; 34-172) ...
Source: Cancer Epidemiology - January 20, 2019 Category: Cancer & Oncology Source Type: research

The diagnostic performance of current tumour markers in surveillance for recurrent testicular cancer: A diagnostic test accuracy systematic review
Publication date: April 2019Source: Cancer Epidemiology, Volume 59Author(s): Brian D. Nicholson, Nicholas R. Jones, Andrew Protheroe, Johnson Joseph, Nia W. Roberts, Ann Van den Bruel, Thomas R. FanshaweAbstractIn this diagnostic test accuracy systematic review we summarise the evidence on the diagnostic accuracy of blood α-fetoprotein (AFP), human chorionic gonadotropin (HCG) and lactate dehydrogenase (LDH) in surveillance for testicular cancer recurrence in adults. We searched four electronic databases for studies that reported the diagnostic accuracy of HCG, AFP, and/or LDH in sufficient detail for sensitivity and...
Source: Cancer Epidemiology - January 17, 2019 Category: Cancer & Oncology Source Type: research

A population-based age-period-cohort study of colorectal cancer incidence comparing Asia against the West
ConclusionOur findings imply an increasing risk of CRC in both Western and Asian populations as their younger cohorts reach older ages. These findings are consistent with the life course argument that macro-environmental changes associated with socio-economic development have specific effects that extend over the life course. Actions that pertain to altering lifestyle-related exposures over the life course are of great importance in combating young CRC risks in the future. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 17, 2019 Category: Cancer & Oncology Source Type: research

Occupational exposure to petroleum-based and oxygenated solvents and oral and oropharyngeal cancer risk in men: A population-based case-control study in France
ConclusionOur results do not provide evidence for a major role of petroleum-based and oxygenated solvents in the occurrence of oral and oropharyngeal cancers in men. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 17, 2019 Category: Cancer & Oncology Source Type: research

Examining determinants of geographic variation in colorectal cancer mortality in North Carolina: A spatial analysis approach
ConclusionOur findings depicted a spatial diffusion process of CRC mortality rates across NC counties, demonstrated intertwined effects between SES deprivation and behavioral risks in shaping CRC mortality at area-level, and identified counties with high CRC mortality that were also deprived in multiple factors. These results suggest interventions to reduce geographic variation in CRC mortality should develop multifaceted strategies and work through shared resources in neighboring areas. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 12, 2019 Category: Cancer & Oncology Source Type: research

Indoor tanning and skin cancer in Canada: A meta-analysis and attributable burden estimation
ConclusionIndoor tanning contributes to a considerable burden of skin cancer in Canada. Strategies aimed at reducing use should be increased and a total ban or restrictions on use and UV-intensity should be considered by health regulators. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 11, 2019 Category: Cancer & Oncology Source Type: research

Colorectal cancer ascertainment through cancer registries, hospital episode statistics, and self-reporting compared to confirmation by clinician: A cohort study nested within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
ConclusionsCancer and death registrations in the UK are a reliable resource for CRC ascertainment in women. Hospital episode statistics can supplement delays in cancer registration. Self-reporting seems less reliable. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 6, 2019 Category: Cancer & Oncology Source Type: research

The rising incidence of testicular cancer among young men in Canada, data from 1971–2015
ConclusionIncidence of testicular cancer has risen dramatically in Canada in recent decades and the cohort effect indicates the need to investigate exposures that have increased since 1945 and that may affect development in young men. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 6, 2019 Category: Cancer & Oncology Source Type: research

Association of rs11801299 and rs1380576 polymorphisms at MDM4 with risk, clinicopathological features and prognosis in patients with retinoblastoma
Conclusionrs11801299 was significantly associated with RB risk, pathological differentiation, tumor aggressiveness and poor prognosis. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 5, 2019 Category: Cancer & Oncology Source Type: research

Healthy lifestyle and breast cancer risk: A case-control study in Morocco
This study aimed to investigate the association between a Healthy Lifestyle Index (HLI) score and BC risk among Moroccan women.MethodsIn this case–control study, 300 incident BC cases and 300 controls, matched by age and area of residence were recruited. Cases were women newly-diagnosed with histopathologically–confirmed BC at the University Hospital in Fez, Morocco. Controls were randomly selected healthy women recruited from 6 primary health centers in Fez. HLI scores developed within this study were assigned to participants based on 11 factors (red and processed meat, white meat, cream, cheese, fish, fruit a...
Source: Cancer Epidemiology - January 5, 2019 Category: Cancer & Oncology Source Type: research