Childhood cancer in India
Publication date: Available online 6 February 2020Source: Cancer EpidemiologyAuthor(s): Shuvadeep Ganguly, Sally Kinsey, Sameer BakhshiAbstractIndia has made significant improvement in childhood cancer services in last few decades. However, the outcome still remains modest as compared to global standards due to significant barriers in recognition, diagnosis and cure.Data regarding comprehensive childhood cancer burden in country is lacking due to low and urban predominant coverage of population-based cancer registry programs. The available data shows lower incidence of childhood cancer incidence especially in leukaemia and...
Source: Cancer Epidemiology - February 6, 2020 Category: Cancer & Oncology Source Type: research

Title page / Editorial Board
Publication date: February 2020Source: Cancer Epidemiology, Volume 64Author(s): (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 22, 2020 Category: Cancer & Oncology Source Type: research

Table of contents
Publication date: February 2020Source: Cancer Epidemiology, Volume 64Author(s): (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 22, 2020 Category: Cancer & Oncology Source Type: research

Childhood cancer: Estimating regional and global incidence
Publication date: Available online 8 January 2020Source: Cancer EpidemiologyAuthor(s): W.T. Johnston, Friederike Erdmann, Robert Newton, Eva Steliarova-Foucher, Joachim Schüz, Eve RomanAbstractBackgroundMost of the world’s population is not covered by cancer surveillance systems or vital registration, and worldwide/UN-regional cancer incidence is estimated using a variety of methods. Quantifying the cancer burden in children (
Source: Cancer Epidemiology - January 9, 2020 Category: Cancer & Oncology Source Type: research

Breast and colorectal cancer recurrence and progression captured by five U.S. population-based registries: Findings from National Program of Cancer Registries patient-centered outcome research
ConclusionsThis study demonstrated that population-based registries given intense support and resources can capture recurrence and offer a generalizable picture of cancer outcomes. Further work on refining definitions, sampling strategies, and novel approaches to capture recurrence could advance the ability of a national cancer surveillance system to contribute to patient-centered outcomes research. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 7, 2020 Category: Cancer & Oncology Source Type: research

Different androgen deprivation therapies might have a differential impact on cognition - An analysis from a population-based study using time-dependent exposure model
ConclusionsVarious ADT therapies may have disparate impacts on cognitive function. Prospective studies exploring pertinent clinical characteristics more fully are needed to confirm these findings. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 7, 2020 Category: Cancer & Oncology Source Type: research

Prevalence and associations of larger burden of intra-anal high-grade squamous intraepithelial lesions at baseline in an Australian cohort of gay and bisexual men: The Study of the Prevention of Anal Cancer
ConclusionThe observation that men with a larger burden of HSIL also had more risk factors for anal cancer suggests this group may warrant closer observation to ensure earlier detection, and thus improved prognosis, of individuals whose HSIL may progress to anal cancer. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 7, 2020 Category: Cancer & Oncology Source Type: research

Combining tumour response and progression free survival as surrogate endpoints for overall survival in advanced colorectal cancer
ConclusionThe joint use of two surrogate endpoints did not lead to marked improvement in the association between treatment effects on surrogate and final endpoints in advanced colorectal cancer. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - January 6, 2020 Category: Cancer & Oncology Source Type: research

Do neighborhood characteristics contribute beyond individual demographics to cancer control behaviors among African American adults?
This study evaluated the unique contribution of neighborhood characteristics (e.g., racial/ethnic diversity, income) beyond individual demographics, to cancer control behaviors in African American men and women.MethodsIndividual-level data were drawn from a national survey (N = 2,222). Participants’ home addresses were geocoded and merged with neighborhood data from the American Community Survey. Multi-level regressions examined the unique contribution of neighborhood characteristics beyond individual demographics, to a variety of cancer risk, prevention, and screening behaviors.ResultsNeighborhood racial/ethnic dive...
Source: Cancer Epidemiology - December 31, 2019 Category: Cancer & Oncology Source Type: research

Anti-diabetic medications and the risk for colorectal cancer: A population-based nested case-control study
Publication date: February 2020Source: Cancer Epidemiology, Volume 64Author(s): Cheol Min Shin, Nayoung Kim, Kyungdo Han, Bongseong Kim, Jin Hyung Jung, Tae Jung Oh, Dong Ho LeeAbstractBackgroundTo evaluate whether anti-diabetic medications are related to colorectal cancer (CRC) risk in type 2 diabetes patients.MethodsThe study was performed from a population-based prospective cohort provided by the National Health Insurance Corporation (2007–2014). Among the 2,084,602 patients newly diagnosed as type 2 diabetes in this period, the cases had incident CRC identified at least 3 years after the diagnosis, and the contro...
Source: Cancer Epidemiology - December 28, 2019 Category: Cancer & Oncology Source Type: research

Risk of second primary papillary thyroid cancer among adult cancer survivors in the United States, 2000-2015
ConclusionsPTC risk was elevated after a range of first primary adult cancers but was not clearly related to treatment. Although surveillance may contribute to elevated short-term risks of PTC, longer-term elevations in regional/distant PTC may be attributable to shared risk factors. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 28, 2019 Category: Cancer & Oncology Source Type: research

Recent cancer incidence trends in Ukraine and short-term predictions to 2022
ConclusionThe anticipated increase in the number of cancer patients in Ukraine clearly has knock-on effects on a healthcare system undergoing reforms. Tobacco control appears to be the only functioning aspect of cancer prevention in the country, and there is a need for a broader national cancer control plan. The continued monitoring and evaluation of implemented cancer control measures by the NCRU will help prioritize targets and allocate future resources to cancer services. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 25, 2019 Category: Cancer & Oncology Source Type: research

Association of cervical and breast cancer mortality with socioeconomic indicators and availability of health services
ConclusionThe importance of organization and equity in the access to health services is highlighted herein, enabling the reorientation of public policies aimed at the minimization of health disparities. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 24, 2019 Category: Cancer & Oncology Source Type: research

History of screening by BreastScreen New South Wales of women with invasive breast cancer
Publication date: February 2020Source: Cancer Epidemiology, Volume 64Author(s): Ming Li, Matthew Warner-Smith, Sarah McGill, David Roder, David CurrowAbstractBackgroundThe principal target age for Australian BreastScreen services was 50–69 years in 1991–2013 and 50–74 years from 2014. History of BreastScreen NSW screening participation of NSW women diagnosed with breast cancer in 2005–2014 was examined using linked BreastScreen and Cancer Registry data.MethodsDifferences in BreastScreen participation were investigated by sociodemographic and tumour characteristics, and diagnostic period, using the P...
Source: Cancer Epidemiology - December 18, 2019 Category: Cancer & Oncology Source Type: research

Associations between area-level deprivation, rural residence, physician density, screening policy and late-stage colorectal cancer in Canada
Publication date: February 2020Source: Cancer Epidemiology, Volume 64Author(s): Alexandra Blair, Geetanjali D. DattaAbstractBackgroundImportant social disparities in colorectal screening exist in Canada. Few studies have assessed disparities further along the cancer control continuum. Here we assess the associations between social and material deprivation, physician density, rural residence, and the absence of provincial mail-based screening programs and colorectal cancer (CRC) stage at diagnosis.MethodsColorectal cancer cases and stage data (“local or regional” if stage 0, I, or II, “late” if stage...
Source: Cancer Epidemiology - December 12, 2019 Category: Cancer & Oncology Source Type: research

Risk factors for ductal carcinoma in situ of the breast in the UK Biobank cohort study
This study was conducted in 263,788 women aged 40–69 years at enrolment into the UK Biobank population-based cohort. Information on demographic, reproductive and health factors was collected at baseline using computerized questionnaires, while incident DCIS was ascertained through linkage to UK cancer registries. Age-adjusted and multivariable hazard ratios were estimated using Cox proportional hazards models in the total sample and by menopausal status. During an average of 7 years of follow-up, 1,016 women developed DCIS. Multivariable analysis indicated that age, physical activity, height, family history of breast...
Source: Cancer Epidemiology - December 12, 2019 Category: Cancer & Oncology Source Type: research

Vitamin D status may help explain survival disparities among racial/ethnic groups of women with ovarian cancer
Publication date: Available online 10 December 2019Source: Cancer EpidemiologyAuthor(s): William B. Grant (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 12, 2019 Category: Cancer & Oncology Source Type: research

Tattoo inks and cancer
Publication date: Available online 11 December 2019Source: Cancer EpidemiologyAuthor(s): Milena Foerster, Ines Schreiver, Andreas Luch, Joachim Schüz (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 12, 2019 Category: Cancer & Oncology Source Type: research

Gender of offspring and risk of ovarian cancer: The HOPE study
ConclusionFetal sex, which influences maternal hormonal milieu, may impact EOC risk. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 10, 2019 Category: Cancer & Oncology Source Type: research

Risk of subsequent malignant neoplasms after an index potentially-human papillomavirus (HPV)-associated cancers
ConclusionsP-HPV-AC survivors experienced excess risk of SPMN. These findings have the potential to affect future surveillance practices and improve preventive healthcare for survivors of P-HPV-ACs. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 7, 2019 Category: Cancer & Oncology Source Type: research

Acute pancreatitis as an early marker of pancreatic cancer and cancer stage, treatment, and prognosis
ConclusionsPancreatic cancer patients with acute pancreatitis diagnosed up to 90 days before cancer diagnosis had earlier stage at diagnosis and better survival than patients without acute pancreatitis. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 5, 2019 Category: Cancer & Oncology Source Type: research

Validity of state cancer registry treatment information for adolescent and young adult women
ConclusionsIn this cohort of young women, population-based cancer registry data on chemotherapy receipt was reasonably accurate and complete in comparison with insurance claims. Radiation and hormone therapy appeared to be less complete. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 5, 2019 Category: Cancer & Oncology Source Type: research

The frequency, nature and impact of GP-assessed avoidable delays in a population-based cohort of cancer patients
ConclusionWe have shown that GP-identified instances of avoidable delay have construct validity. Whilst the causes of avoidable diagnostic delays are multi-factorial and occur in different settings and phases of the diagnostic process, their analysis can guide improvement initiatives and enable the examination of any prognostic implications. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 4, 2019 Category: Cancer & Oncology Source Type: research

A response to: Vitamin D status may help explain survival disparities among racial/ethnic groups of women with ovarian cancer
Publication date: Available online 4 December 2019Source: Cancer EpidemiologyAuthor(s): Ashley E. Stenzel, Kirsten B. Moysich (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - December 4, 2019 Category: Cancer & Oncology Source Type: research

Access to diagnostic facilities in children with cancer in Colombia: Spotting opportunity and distance from a sample
ConclusionsThis study identified clear shortcomings in the Colombian Health System related to the quality of childhood cancer-related health care in terms of timeliness, cancer networks, and geographic access. These inequities not only depend on sociodemographic-characteristics and should be intervened upon. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 29, 2019 Category: Cancer & Oncology Source Type: research

Title page / Editorial Board
Publication date: December 2019Source: Cancer Epidemiology, Volume 63Author(s): (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 27, 2019 Category: Cancer & Oncology Source Type: research

Table of contents
Publication date: December 2019Source: Cancer Epidemiology, Volume 63Author(s): (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 27, 2019 Category: Cancer & Oncology Source Type: research

Racial/ethnic and socioeconomic survival disparities for children and adolescents with central nervous system tumours in the United States, 2000–2015
Publication date: February 2020Source: Cancer Epidemiology, Volume 64Author(s): Hannah K. Mitchell, Melanie Morris, Libby Ellis, Renata Abrahão, Audrey BonaventureAbstractBackground and objectivesCentral nervous system (CNS) malignancy is the commonest cause of cancer death in children and adolescents (0–19 years) in high-income settings. There is limited data on survival inequalities by race/ethnicity and socioeconomic position (SEP), for young patients, we aim to analyse their influence on survival from childhood CNS tumour.Methods9577 children and adolescents diagnosed with primary malignant CNS tumours dur...
Source: Cancer Epidemiology - November 26, 2019 Category: Cancer & Oncology Source Type: research

Vasectomy and the risk of prostate cancer in a Finnish nationwide population-based cohort
ConclusionWe found a small statistically significant increase in PCa incidence after vasectomy, but in contrast the mortality of vasectomized men was significantly reduced. This may be due to higher likelihood of vasectomized men to undergo prostate-specific antigen testing, having healthier general lifestyle and other biological factors e.g. high reproductive fitness. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 23, 2019 Category: Cancer & Oncology Source Type: research

Patient-reported outcome measures after treatment for prostate cancer: Results from the Danish Prostate Cancer Registry (DAPROCAdata)
ConclusionClinical interventions for improving symptoms should focus particularly on the first year after prostate cancer diagnosis. Greater emphasis on improving sexual function should be practiced in clinical and rehabilitative care, since this area has the single greatest impact on symptom-specific QoL after primary treatment for prostate cancer. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 23, 2019 Category: Cancer & Oncology Source Type: research

Risk factors for gastric precancerous and cancers lesions in Latin American counties with difference gastric cancer risk
ConclusionThe present study in Latin American countries confirmed that similar environmental factors such as smoking and grain/cereal consumption were associated with H. pylori infection and its induced gastric lesions as reported in other regions where dominant H. pylori strains differ. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 20, 2019 Category: Cancer & Oncology Source Type: research

Adherence to the 2018 WCRF/AICR cancer prevention guidelines and chronic lymphocytic leukemia in the MCC-Spain study
ConclusionOverall, our results do not support an association between the WCRF/AICR score and CLL, yet we might have been limited by statistical power and study design to detect modest associations. Further research, ideally with a prospective design, long follow-up, and including additional lymphoma subtypes, is warranted to confirm the impact of composite healthy lifestyle behaviors on lymphoma risk. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 20, 2019 Category: Cancer & Oncology Source Type: research

Response to Letter to the Editor: Metformin in colorectal cancer: A match ruled by MiR26b?
Publication date: Available online 16 November 2019Source: Cancer EpidemiologyAuthor(s): Donata Linkeviciute-Ulinskiene, Audrius Dulskas, Ausvydas Patasius, Lina Zabuliene, Vincas Urbonas, Giedre Smailyte (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 17, 2019 Category: Cancer & Oncology Source Type: research

Identifying skeletal-related events for prostate cancer patients in routinely collected hospital data
ConclusionThe comparison of the cumulative incidence of SREs identified in routinely collected hospital data, based on a specific coding definition in patients diagnosed with different prostate cancer stage, supports their validity as a clinically important marker of cancer progression. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 9, 2019 Category: Cancer & Oncology Source Type: research

Metformin in colorectal cancer: A match ruled by MiR26b?
Publication date: Available online 6 November 2019Source: Cancer EpidemiologyAuthor(s): Raffaella Mormile (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 8, 2019 Category: Cancer & Oncology Source Type: research

Seven years prevalence and distribution of high and low risk HPV genotypes in women living in the metropolitan area of Naples
The objective of this work was to provide an update information on HPV age/genotype distribution by retrospectively analyzing a cohort of women living in the metropolitan area of Naples.MethodsFrom January 2011 to December 2017, cervical scrape specimens from 1265 women, with abnormal cytological indication, were tested for HPV DNA. The presence and the viral genotypes were assessed by the Linear Array HPV genotyping test for the detection of 37 anogenital HPV-DNA genotypes.ResultsThe overall prevalence of HPV infections was of 44.5% (95% CI 41.77–47.24). Among HR-HPV types, HPV-16 was the most common identified geno...
Source: Cancer Epidemiology - November 7, 2019 Category: Cancer & Oncology Source Type: research

Breast cancer staging by subtype in the Lower Mississippi Delta region States
ConclusionsBlack women in the Delta had higher rates of late-stage cancers across subtypes. Culturally competent interventions targeting risk-appropriate screening modalities should be scaled up in the Delta to improve early detection. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - November 2, 2019 Category: Cancer & Oncology Source Type: research

Population trends in emergency cancer diagnoses: The role of changing patient case-mix
ConclusionChanges in case-mix (particularly that of cancer sites) account for about a fifth of the overall reduction in emergency presentations. This would support the use of adjustment/standardisation of reported statistics to support their interpretation and help appreciate the influence of case-mix, particularly regarding cancer sites with changing incidence. However, most of the reduction in emergency presentations remains unaccounted for, and likely reflects genuine changes during the study period in how patients were being diagnosed. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - October 24, 2019 Category: Cancer & Oncology Source Type: research

Effect of body-mass index on the risk of gastric cancer: A population-based cohort study in A Japanese population
ConclusionOur result suggests that gastric cancer risk increases for men with BMI ≥ 27 kg/m2. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - October 24, 2019 Category: Cancer & Oncology Source Type: research

Variations in prostate biopsy recommendation and acceptance confound evaluation of risk factors for prostate cancer: Examining race and BMI
ConclusionsDifferential disease classification among men who may be recommended to undergo and then consider whether to accept a prostate biopsy leads to inaccurate identification of prostate cancer risk factors. Imputing a man’s prostate cancer status reduces detection bias. Covariate adjustment does not address the problem of outcome misclassification. Cohorts evaluating incident prostate cancer should collect longitudinal screening and biopsy data to adjust for this potential bias. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - October 20, 2019 Category: Cancer & Oncology Source Type: research

Hospitalization outcomes and racial disparities in cervical cancer patients: An analysis of the national inpatient sample data from 2002 to 2014
We examined racial differences in hospitalization outcomes; length of stay (LOS) in hospital, mortality in hospital, post-operative complications in patients who underwent hysterectomy and discharge disposition. Patients were matched on age at primary diagnosis, insurance status, residential region, and median income of residential area, modified Deyo comorbidity index, stage of disease and treatment. Categorical outcomes were analyzed by conditional logistic regression accounting for matched study design and odds ratios (95%CI) were reported. LOS was analyzed using t-test and beta estimate for difference in means was repo...
Source: Cancer Epidemiology - October 19, 2019 Category: Cancer & Oncology Source Type: research

Is colorectal cancer a more aggressive disease in young patients? A population-based study from the Czech Republic
ConclusionThe better prognosis in young patients is presumably due to their better physiological reserve and lower incidence of comorbidities. Efforts should be made in younger patients to diagnose early and treat aggressively. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - October 19, 2019 Category: Cancer & Oncology Source Type: research

Assisted reproductive technology and the risk of pediatric cancer: A population based study and a systematic review and meta analysis
ConclusionsBased on very large numbers, ART in general, and IVF in particular, are not associated with overall increased risk of pediatric cancer. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - October 12, 2019 Category: Cancer & Oncology Source Type: research

Analysis of racial disparities in the treatment and outcomes of colorectal cancer in young adults
Publication date: December 2019Source: Cancer Epidemiology, Volume 63Author(s): Olatunji B. Alese, Renjian Jiang, Katerina M. Zakka, Christina Wu, Walid Shaib, Mehmet Akce, Madhusmita Behera, Bassel F. El-RayesAbstractBackgroundThe incidence of colorectal cancer (CRC) in young adults is increasing. Minority populations with CRC are known to have worse survival outcomes. The aim of this study is to evaluate adults under age 50 years with CRC by race and ethnicity.MethodsData were obtained from all US hospitals that contributed to the National Cancer Database (NCDB) between 2004 and 2013. Univariate and multivariable testing...
Source: Cancer Epidemiology - October 9, 2019 Category: Cancer & Oncology Source Type: research

Population risk factors for late-stage presentation of cervical cancer in sub-Saharan Africa. Stewart et al Cancer Epidemiol. 2018 Apr; 53:81-92
Publication date: Available online 5 October 2019Source: Cancer EpidemiologyAuthor(s): Donald Maxwell Parkin (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - October 5, 2019 Category: Cancer & Oncology Source Type: research

Trends in cancer incidence in the Republic of Mauritius, 1991–2015
ConclusionThe most common cancers were those associated with 'westernisation' of lifestyle. Our figures contrast with other Sub-Saharan Africa countries where infection related cancers are most predominant. The MNCR has also improved its data quality over time. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - October 5, 2019 Category: Cancer & Oncology Source Type: research

Age at start of using tobacco on the risk of head and neck cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium (INHANCE)
Publication date: December 2019Source: Cancer Epidemiology, Volume 63Author(s): Chun-Pin Chang, Shen-Chih Chang, Shu-Chun Chuang, Julien Berthiller, Gilles Ferro, Keitaro Matsuo, Victor Wünsch-Filho, Tatiana N. Toporcov, Marcos Brasilino de Carvalho, Carlo La Vecchia, Andrew F. Olshan, Jose P. Zevallos, Diego Serraino, Joshua Muscat, Erich M. Sturgis, Guojun Li, Hal Morgenstern, Fabio Levi, Luigino Dal Maso, Elaine SmithAbstractBackgroundTobacco use is a well-established risk factor for head and neck cancer (HNC). However, less is known about the potential impact of exposure to tobacco at an early age on HNC risk.Meth...
Source: Cancer Epidemiology - October 5, 2019 Category: Cancer & Oncology Source Type: research

Treatment trajectory of tobacco-related cancer patients: A study in Assam, India
ConclusionsThe study suggests addressing the beliefs and practices associated with cancer care (both modern and traditional) by engaging mass awareness. Need for designing cancer-education programmes for the general population was also advocated. (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - October 2, 2019 Category: Cancer & Oncology Source Type: research

Title page / Editorial Board
Publication date: October 2019Source: Cancer Epidemiology, Volume 62Author(s): (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - September 28, 2019 Category: Cancer & Oncology Source Type: research

Table of contents
Publication date: October 2019Source: Cancer Epidemiology, Volume 62Author(s): (Source: Cancer Epidemiology)
Source: Cancer Epidemiology - September 28, 2019 Category: Cancer & Oncology Source Type: research