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Cancer: Brain Cancers
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Total 26098 results found since Jan 2013.
In search of the stroke detector
Up to 50% of stroke diagnoses are inaccurate. What if a small biosensor could do the job precisely? Robert McCrum, who survived a ‘brain attack’ 22 years ago, traces one team’s long journey to a breakthroughStroke, or “brain attack”, is the third biggest killer in the western world, after cancer and heart failure. The life-changing effects associated with this simple, Anglo-Saxon word are readily explained: a stroke occurs when the blood supply to the brain is disrupted by a blood vessel either bursting or blocking, so that the part of the brain supplied by this blood vessel dies.The brain is a much more com...
Source: Guardian Unlimited Science - January 22, 2017 Category: Science Authors: Robert McCrum Tags: Medical research Health NHS Biochemistry and molecular biology Neuroscience Society Source Type: news
Clinical outcome and molecular characterization of brain metastases from esophageal and gastric cancer: a systematic review
AbstractThe aim of the study was to collect the available data on central nervous system (CNS) metastases from esophageal and gastric cancer. A PubMed, EMBASE, SCOPUS, Web of Science, LILACS, Ovid and Cochrane Library search was performed. Thirty-seven studies including 779 patients were considered. Among the data extracted, treatment of tumor and brain metastases (BMs), time to BMs development, number and subsite, extracerebral metastases rate, median overall survival (OS) and prognostic factors were included. For esophageal cancer, the median OS from diagnosis of BMs was 4.2 months. Prognostic factors for OS included: ...
Source: Medical Oncology - March 17, 2017 Category: Cancer & Oncology Source Type: research
A novel germline TP53 mutation p.Pro190Arg detected in a patient with lung and bilateral breast cancers.
CONCLUSION: We identified novel germline mutation of TP53.
PMID: 28499267 [PubMed - as supplied by publisher]
Source: Advances in Medical Sciences - May 9, 2017 Category: Biomedical Science Authors: Krześniak M, Butkiewicz D, Rachtan J, Matuszczyk I, Grzybowska E, Rusin M Tags: Adv Med Sci Source Type: research
Inequalities in Cancer Deaths by Age, Gender and Education.
CONCLUSIONS: The results can be useful for economists to define the health priorities in each country, make the financial decisions in economics, and thus contribute to better health, economic growth, as well as effective spending of health expenditures.
PMID: 29524371 [PubMed - in process]
Source: Central European Journal of Public Health - March 12, 2018 Category: International Medicine & Public Health Tags: Cent Eur J Public Health Source Type: research
Longitudinal investigation of cognitive deficits in breast cancer patients and their gray matter correlates: impact of education level
AbstractCognitive deficits are a major complaint in breast cancer patients, even before chemotherapy. Comprehension of the cerebral mechanisms related to cognitive impairment in breast cancer patients remains difficult due to the scarcity of studies investigating both cognitive and anatomical imaging changes. Furthermore, only some of the patients experienced cognitive decline following chemotherapy, yet few studies have identified risk factors for cognitive deficits in these patients. It has been shown that education level could impact cognitive abilities during the recovery phase following chemotherapy. Our main aim was ...
Source: Brain Imaging and Behavior - November 7, 2018 Category: Neurology Source Type: research
Contemporary practice patterns of stereotactic radiosurgery for brain metastasis: A review of published Australian literature
SummaryThere has been a shift in the management of brain metastasis (BM), with increasing use of stereotactic radiosurgery (SRS) and delaying/avoiding whole ‐brain radiotherapy (WBRT), given the concern regarding the long‐term neurocognitive effect and quality of life impact of WBRT. It is, however, unclear as to the contemporary practice pattern and outcomes of SRS in Australia. We conducted a literature search in PubMed and MEDLINE using a series of keywords: ‘stereotactic’, ‘radiosurgery’ and ‘brain metastases’, limiting to Australian studies, which report on clinical outcomes following SRS. Eight studie...
Source: Journal of Medical Imaging and Radiation Oncology - August 27, 2019 Category: Radiology Authors: Wee Loon Ong,
Morikatsu Wada,
Jeremy Ruben,
Farshad Foroudi,
Jeremy Millar Tags: Radiation Oncology —Review Article Source Type: research
How Does Gaucher Disease Present?
Discussion
Gaucher disease (GD) was first described by Philippe Gaucher in 1882. It was the first lysosomal storage disease (LSD) described and is the comparison prototype for many variations and their treatment. There are about 50 LSD and more well-known ones include Fabry, Niemann-Pick and Pompe diseases. LSDs currently have more than 300 different enzymes or membrane proteins affected which cause central nervous system and visceral disease. Overall the frequency of LSDs in aggregate is 1:3000 – 7000 live births. GD has an estimated prevalence of 1:57,000 – 111,000. It is higher within the Ashkenazi Jewish po...
Source: PediatricEducation.org - December 9, 2019 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Who Gets Pott ’ s Puffy Tumor?
Discussion
Pott’s puffy tumor (PPT) was first described by Sir Percivall Pott in 1775 and who also described other orthopaedic and oncological diseases subsequently named for him. “It is a subperiosteal abscess of the anterior wall of the frontal sinus associated with underlying frontal osteomyelitis.” The tender edema and swelling of the forehead is the sign of PPT. Associated fever, headache, and rhinorrhea along with similar problems such as postnasal drip or nasal congestion are common. Associated ophthalmological problems include peri-orbital or eyelid edema and/or preseptal cellulitis. Ptosis and di...
Source: PediatricEducation.org - March 1, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Cancers, Vol. 13, Pages 3028: Co-Deregulated miRNA Signatures in Childhood Central Nervous System Tumors: In Search for Common Tumor miRNA-Related Mechanics
Conclusions: Our approach could prove significant in the search for global miRNA targets for tumor diagnosis and therapy. To the best of our knowledge, there are no previous reports concerning the present approach.
Source: Cancers - June 17, 2021 Category: Cancer & Oncology Authors: George I. Lambrou Apostolos Zaravinos Maria Braoudaki Tags: Article Source Type: research
What Causes Irritability?
Discussion
Child abuse or non-accidental trauma is a clinical diagnosis. It is the constellation of history, physical examination, radiographic evaluation, laboratory testing and investigation that determines if child abuse has occurred. Irritability caused by fractures or other trauma can be a presenting symptom of abuse. Fractures can be a presentation but they are also common problems not associated with abuse. Femoral shaft fractures are estimated to account for only 1.6% of all fractures in children, therefore they are potentially more suspicious for child abuse. A review of femur fractures can be found here. A review...
Source: PediatricEducation.org - October 18, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Multimodal Medical Image Fusion of Positron Emission Tomography and Magnetic Resonance Imaging Using Generative Adversarial Networks
Behav Neurol. 2022 Apr 14;2022:6878783. doi: 10.1155/2022/6878783. eCollection 2022.ABSTRACTMultimodal medical image fusion is a current technique applied in the applications related to medical field to combine images from the same modality or different modalities to improve the visual content of the image to perform further operations like image segmentation. Biomedical research and medical image analysis highly demand medical image fusion to perform higher level of medical analysis. Multimodal medical fusion assists medical practitioners to visualize the internal organs and tissues. Multimodal medical fusion of brain ima...
Source: Behavioural Neurology - April 25, 2022 Category: Neurology Authors: R Nandhini Abirami P M Durai Raj Vincent Kathiravan Srinivasan K Suresh Manic Chuan-Yu Chang Source Type: research
The global prevalence of primary central nervous system tumors: a systematic review and meta-analysis
ConclusionAs a result, it can be stated that brain tumors are the most common type of primary CNS tumors. It was also observed that tumors involving neuroepithelial cells are more common in patients than other types of tumors.
Source: European Journal of Medical Research - January 20, 2023 Category: Research Source Type: research
Do animal models of brain tumors replicate human peritumoral edema? a systematic literature search
ConclusionNo animal model currently exists that enable the investigation of novel candidates for the treatment of peritumoral brain edema. With current interest in alternative treatments for peritumoral brain edema, there is an unmet need for clinically relevant animal models.
Source: Journal of Neuro-Oncology - February 9, 2023 Category: Cancer & Oncology Source Type: research
The trend of opioid prescriptions among cancer patients in a tertiary hospital: A multimethod quantitative study
ConclusionOpioid use in cancer patients in this study is lower than the average global usage. Promoting opioid prescriptions for pain management through medical education can help doctors overcome opiophobia.
Source: Frontiers in Oncology - April 11, 2023 Category: Cancer & Oncology Source Type: research
