MGH researchers identify key elements of cellular response to proteasome dysfunction
(Massachusetts General Hospital) Massachusetts General Hospital investigators have identified key molecules in the pathway by which cells in the C. elegans roundworm sense proteasome dysfunction, findings that may have application to treatment of several human diseases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 16, 2016 Category: Cancer & Oncology Source Type: news
Plastic manufacturing chemical BPS harms egg cells, study suggests
This study clearly illustrates the issue with the ‘whack-a-mole’ approach to chemical replacement in consumer products,” said Patrick Allard, assistant professor of environmental health sciences at the UCLA Fielding School of Public Health, and the study’s senior author. “There is a great need for the coordinated safety assessment of multiple substitutes and mixtures of chemicals before their use in product replacement. But the good news is that a number of governmental programs and academic labs are now moving in that direction”.
AUTHORS
The authors of the study are Yichang Chen, Le Shu, Zhiqun Qiu, Dong Yeon ...
Source: UCLA Newsroom: Health Sciences - August 9, 2016 Category: Universities & Medical Training Source Type: news
New research points to novel approach to tackling Ascaris roundworm
(Trinity College Dublin) Scientists have shed new light on Ascaris infection, which affects 1 billion people worldwide. Targeting specific liver proteins may offer new preventative options against an infection that kills around 60.000 people each year. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 4, 2016 Category: Infectious Diseases Source Type: news
Sex and death insights from a mutant roundworm
All at once, a roundworm overhauls an array of survival strategies, and researchers suspect multiple mutations behind it. But they ' re surprised when they trace the sweeping changes back to one tiny mutation on a single gene, and find a hint at a genetic regulator of so-called life history trade-offs. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 28, 2016 Category: Science Source Type: news
Sex and death insights from a mutant roundworm
( < i > Georgia Institute of Technology < /i > ) All at once, a roundworm overhauls an array of survival strategies, and researchers suspect multiple mutations behind it. But they're surprised when they trace the sweeping changes back to one tiny mutation on a single gene, and find a hint at a genetic regulator of so-called life history trade-offs. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 28, 2016 Category: Biology Source Type: news
Dietary restriction increases lifespan through effects on the gut
Dietary restriction, or limited food intake without malnutrition, has beneficial effects on longevity in many species, including humans. A new study represents a major advance in understanding how dietary restriction leads to these advantages. Using the small roundworm C. elegans as a model, scientists showed that autophagy in the intestine is critical for lifespan extension. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 14, 2016 Category: Science Source Type: news
Study links developmental, lipid handling pathways in C. elegans
A previously unknown interaction between metabolic pathways in two different tissues within the C.elegans roundworm triggers a key step in maturation, scientists have discovered. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 13, 2016 Category: Science Source Type: news
Pomegranate compound 'could combat' complications of ageing
Conclusion
This was a mixed animal study that aimed to investigate the effect of compounds called urolithins first in roundworms and then rodents. Urolithins are formed during the breakdown of ellagitannins, which are found in pomegranates, nuts and berries. It was not known whether urolithins were just a waste product, or if they had any beneficial effects.
The study found that one of the urolithins in particular, urolithin A, seems to improve muscle function in rodents. We do not know conclusively why, but the results suggested this was due to improving the quality of the mitochondria by increasing the rate of destructi...
Source: NHS News Feed - July 13, 2016 Category: Consumer Health News Tags: Food/diet Medication Source Type: news
Mass. General study links developmental and lipid handling pathways in C. elegans
(Massachusetts General Hospital) A Massachusetts General Hospital research team reports finding that a previously unknown interaction between metabolic pathways in two different tissues within the C.elegans roundworm triggers a key step in maturation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2016 Category: Global & Universal Source Type: news
Filarial nematodes taking a fancy to Austria
In Austria, the parasitic roundworms Dirofilaria repens and Dirofilaria immitis are usually considered to be unpleasant souvenirs from travels abroad. A preliminary study has identified indigenous mosquitoes as carriers of Dirofilaria repens, suggesting for the first time that the parasite has become endemic in Eastern Austria. Dirofilaria immitis, commonly known as heartworm, also appears to be on the verge of becoming autochthonous. The slow pace at which the parasites are establishing themselves is probably due in part to the keeping conditions of dogs in Austria. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 10, 2016 Category: Science Source Type: news
Impax Announces Availability of EMVERM(TM) (mebendazole) Chewable Tablets, 100 mg
EMVERM Provides a New Option for Patients with Pinworm, Whipworm, Roundworm and Hookworm in Single or Mixed Infections
HAYWARD, Calif., April 13, 2016 -- (Healthcare Sales & Marketing Network) -- Impax Laboratories, Inc. (IPXL)today announced that EMVE... Biopharmaceuticals, Product LaunchImpax Laboratories, EMVERM, mebendazole (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 13, 2016 Category: Pharmaceuticals Source Type: news
Discovery in roundworms may one day help humans with spinal cord injury and paralysis
A newly discovered pathway leading to the regeneration of central nervous system (CNS) brain cells (neurons) in a type of roundworm (C. elegans) sheds light on the adult human nervous system's ability to regenerate. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 12, 2016 Category: Science Source Type: news
Discovery in roundworms may one day help humans with spinal cord injury and paralysis
(Boston University Medical Center) A newly discovered pathway leading to the regeneration of central nervous system (CNS) brain cells (neurons) in a type of roundworm (C. elegans) sheds light on the adult human nervous system's ability to regenerate. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 11, 2016 Category: Global & Universal Source Type: news
For the perfect eggs, roundworms use small RNAs
All multicellular organisms that reproduce sexually rely on eggs to support early life. Researchers used the tiny roundworm C. elegans as a model to better understand how eggs enable embryonic development, using only the materials already present in them. Their study uncovers the role small RNAs and helper proteins play in fine-tuning egg development. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 24, 2016 Category: Science Source Type: news
Mating without males decreases lifespan
Roundworm species reproducing self-fertilization instead of mating with males have shorter lifespans. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 3, 2016 Category: Science Source Type: news
