First Complete Wiring Diagram of an Animal's Nervous System
July 3, 2019—(BRONX, NY)—In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism. The study includes adults of both sexes and reveals substantial differences between them. (Source: Einstein News)
Source: Einstein News - July 3, 2019 Category: Universities & Medical Training Source Type: news
Perfect timing: Making the 'switch' from juvenile to adult
(University of Rochester Medical Center) Very little is known about how the onset of puberty is controlled in humans, but the discovery of a new gene in the roundworm C. elegans could be the 'missing link' that determines when it's time to make this juvenile-to-adult transition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 3, 2019 Category: International Medicine & Public Health Source Type: news
Gruesome footage shows a 1ft WORM being pulled from a woman's bowels
The woman, known only as Ms Yang, 41, had been battling abdominal pain for a decade. After multiple trips to hospital, doctors in East China's Zhejiang Province discovered the roundworm on June 14. (Source: the Mail online | Health)
Source: the Mail online | Health - June 18, 2019 Category: Consumer Health News Source Type: news
Long-lived roundworms helped identify new anti-aging compounds among FDA approved drugs
(Gero) Researchers from Gero, Skolkovo Institute of Science and Technology (Skoltech), Moscow Institute of Physics and Technology (MIPT), and University of Arkansas for Medical Sciences (UAMS) collaborated to derive a transcriptomic signature of aging, which they confirmed using large transcriptomic databases. They discovered that aging in nematodes is partially programmed and can be therapeutically reversed by a number of FDA-approved drugs. The study is published in Scientific Reports. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 22, 2019 Category: International Medicine & Public Health Source Type: news
Long-lived roundworms help identify new anti-aging compounds among the FDA approved drugs
(Moscow Institute of Physics and Technology) Researchers from Gero, Skolkovo Institute of Science and Technology (Skoltech), Moscow Institute of Physics and Technology (MIPT), and University of Arkansas for Medical Sciences (UAMS) collaborated to derive a transcriptomic signature of aging, which they confirmed using large transcriptomic databases. They discovered that aging in nematodes is partially programmed and can be therapeutically reversed by a number of FDA-approved drugs. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 22, 2019 Category: International Medicine & Public Health Source Type: news
C. elegans roundworms 'harvest' an essential coenzyme from the bacteria they consume
(Massachusetts General Hospital) A study conducted in C.elegans nematode roundworms may lead to improved treatment of a rare human genetic disorder that causes severe neurological symptoms leading to death in early childhood. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 26, 2019 Category: International Medicine & Public Health Source Type: news
Discovery of life-extension pathway in worms demonstrates new way to study aging
(Scripps Research Institute) An enzyme-blocking molecule can extend the lifespan of Caenorhabditis elegans roundworms by as much as 45 percent, largely by modulating a cannabinoid biological pathway, according to a study from scientists at Scripps Research. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 25, 2019 Category: International Medicine & Public Health Source Type: news
Experiments with roundworms suggest alternatives for the treatment of schizophrenia
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Researchers used C. elegans as an animal model to investigate the importance of certain human genes for the treatment of schizophrenia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 19, 2019 Category: International Medicine & Public Health Source Type: news
Rice U. study highlights danger of vitamin B12 deficiency
(Rice University) Using roundworms, one of Earth's simplest animals, Rice University bioscientists have found the first direct link between a diet containing too little vitamin B12 and an increased risk of infection by two potentially deadly pathogens. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 13, 2019 Category: Cancer & Oncology Source Type: news
Long-lived parents produce better quality offspring
(University of East Anglia) New research shows that long-lived parents produce better quality offspring.Researchers studied a gene associated with ageing in roundworms. They found that by reducing this gene's expression, they could not only more than double the worm's lifespan - but also improve the fitness of its offspring.The findings support an emerging new theory that we have genes that age us, and that shutting down these genes in later life could one day help us stay younger and healthier for longer. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 4, 2019 Category: International Medicine & Public Health Source Type: news
Inside the brains of hungry worms, researchers find clues about how they hunt
(Rockefeller University) When looking for food, the roundworm C. elegans searches the same area for up to 20 minutes before trying its luck at more distant locales. New research on the worm's brain explains how this behavior arises at the level of molecules and cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2019 Category: International Medicine & Public Health Source Type: news
The smell of food controls cellular recycling and affects life expectancy
(University of Cologne) The smell of food affects physiology and aging. That is the result of research conducted on the model organism of the roundworm by a research team led by Professor Thorsten Hoppe at the Cluster of Excellence for Aging Research (CECAD). Surprisingly, this relationship is due to a single pair of olfactory neurons. The results have now been published in Nature Metabolism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2019 Category: International Medicine & Public Health Source Type: news
University of Konstanz develops first genetic switch for C. elegans
(University of Konstanz) With their first ever RNA-based inducible system for switching on genes in the roundworm Caenorhabditis elegans, two researchers from the University of Konstanz have closed a significant gap in the research on and usage of genetic switches. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 30, 2019 Category: International Medicine & Public Health Source Type: news
New findings on genes that drive male-female brain differences, timing of puberty
(Columbia University) Columbia University researchers have discovered a group of genes in roundworms that control the onset of puberty and induce sex differences in neural structures that raise new questions of whether differences in male and female behavior are hardwired in our brains. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 2, 2019 Category: International Medicine & Public Health Source Type: news
