Brain Aneurysm Risk Examined in Polycystic Kidney Disease
THURSDAY, Aug. 1, 2019 -- Intracranial aneurysms are detected in 9 percent of patients with autosomal dominant polycystic kidney disease (ADPKD) undergoing magnetic resonance angiography (MRA) screening, according to a study published online July 30... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 1, 2019 Category: Pharmaceuticals Source Type: news
Autosomal-dominant Polycystic Kidney Disease: 3 Studies in Brief
Three new studies on ADPKD treatment project long-term impact of tolvaptan; reveal potential in an existing drug class; and, report success in slowing comorbid hepatic disease. (Source: ConsultantLive)
Source: ConsultantLive - July 8, 2019 Category: Internal Medicine Authors: Andrew D. Bowser Tags: Kidney Disease Source Type: news
KC charity will invest $5M to fund research into a cure for PKD
The PKD Foundation will invest nearly $5 million on research over the next two years to fund treatment studies and research polycystic kidney disease.
"For the past 36 years, our goal has been to support PKD patients from care to cure. With the support of generous donations, we have the ability to stand beside PKD patients until there is a cure, supporting research for new treatments and to support researchers," PKD Foundation CEO Andy Betts sai d in a news release.
The foundation announced that… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - June 25, 2019 Category: American Health Authors: Lily Lieberman Source Type: news
KC charity will invest $5M to fund research into a cure for PKD
The PKD Foundation will invest nearly $5 million on research over the next two years to fund treatment studies and research polycystic kidney disease.
"For the past 36 years, our goal has been to support PKD patients from care to cure. With the support of generous donations, we have the ability to stand beside PKD patients until there is a cure, supporting research for new treatments and to support researchers," PKD Foundation CEO Andy Betts sai d in a news release.
The foundation announced that… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - June 25, 2019 Category: Biotechnology Authors: Lily Lieberman Source Type: news
Polycystic Kidney Disease (PKD)
Title: Polycystic Kidney Disease (PKD)Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 6/17/2019 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - June 17, 2019 Category: Nutrition Source Type: news
Too close not to encyst: Polycystic kidney disease and interorganellar contact sites
Mitofusin 2 (MFN2) tethers mitochondria to the endoplasmic reticulum (ER). In the 7 May 2019 issue of Science Signaling, Kuo et al. report that polycystin 2 (PC2), encoded by a gene mutated in type 2 autosomal dominant polycystic kidney disease (ADPKD), contributes to cystogenesis by affecting MFN2, thus extending the role of mitochondria-ER contact sites to a common genetic disorder. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - May 27, 2019 Category: Science Authors: Lorenzi, I., Scorrano, L. Tags: STKE Focus Source Type: news
Polycystic Kidney Disease: Studies on Obesity, Pain, Screening
Find summaries here of 3 recent studies conducted to shed light on difficult issues in the management of autosomal dominant polycystic kidney disease: (Source: ConsultantLive)
Source: ConsultantLive - May 10, 2019 Category: Internal Medicine Authors: Andrew Bowser Tags: Kidney Disease Source Type: news
New strategy for untreatable kidney disease: targeting cell energy
By targeting a protein called Polycystin 2, Yale researchers have identified a promising approach for treating autosomal dominant polycystic kidney disease. (Source: Yale Science and Health News)
Source: Yale Science and Health News - May 7, 2019 Category: Universities & Medical Training Source Type: news
Polycystic Kidney Disease: What & #039;s Your ADPKD IQ?
Autosomal dominant polycystic kidney disease is the most common form of polycystic renal disease. Find out what you know about ADPKD with this 7-question quiz on epidemiology, diagnosis, and more. (Source: ConsultantLive)
Source: ConsultantLive - May 6, 2019 Category: Internal Medicine Authors: Andrew D. Bowser Tags: Kidney Disease Source Type: news
Polycystic Kidney Disease: How Much Do You Know?
Autosomal dominant polycystic kidney disease us the most common form of polycystic renal disease. Find out what you know about ADPKD with this 7-question quiz on epidemiology, diagnosis, and more. (Source: ConsultantLive)
Source: ConsultantLive - May 6, 2019 Category: Internal Medicine Authors: Andrew D. Bowser Tags: Kidney Disease Source Type: news
Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2
Mitochondria and the endoplasmic reticulum (ER) have an intimate functional relationship due to tethering proteins that bring their membranes in close (~30 nm) apposition. One function of this interorganellar junction is to increase the efficiency of Ca2+ transfer into mitochondria, thus stimulating mitochondrial respiration. Here, we showed that the ER cation-permeant channel polycystin 2 (PC2) functions to reduce mitochondria-ER contacts. In cell culture models, PC2 knockdown led to a 50% increase in mitofusin 2 (MFN2) expression, an outer mitochondrial membrane GTPase. Live-cell super-resolution and electron microscopy ...
Source: Signal Transduction Knowledge Environment - May 6, 2019 Category: Science Authors: Kuo, I. Y., Brill, A. L., Lemos, F. O., Jiang, J. Y., Falcone, J. L., Kimmerling, E. P., Cai, Y., Dong, K., Kaplan, D. L., Wallace, D. P., Hofer, A. M., Ehrlich, B. E. Tags: STKE Research Articles Source Type: news
An international prize honors Bradley Yoder for research in polycystic kidney disease
(University of Alabama at Birmingham) Bradley K. Yoder, Ph.D., professor and chair of the Department of Cell, Developmental and Integrative Biology at the University of Alabama at Birmingham, has been awarded with a Lillian Jean Kaplan International Prize for Advancement for his significant research in the polycystic kidney field. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 29, 2019 Category: Biology Source Type: news
Infographic: Polycystic kidney disease (PKD)
Learn more about polycystic kidney disease. Other health tip infographics: mayohealthhighlights.startribune.com? (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - February 6, 2019 Category: Databases & Libraries Source Type: news
Tolvaptan listed for polycystic kidney disease in Australia
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - January 1, 2019 Category: Drugs & Pharmacology Source Type: news
Seeing is believing: Monitoring real time changes during cell division
(Lancaster University) Scientist have cast new light on the behaviour of tiny hair-like structures called cilia found on almost every cell in the body. Cilia play important roles in human development and disease. Akin to tiny antennae, they act as cell timers keeping the brakes on cell division until the right growth cues are received. Malfunction of cilia leads to many human diseases such as polycystic kidney disease and cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 19, 2018 Category: Cancer & Oncology Source Type: news
