Which Factors Predict Rapid Decline in Polycystic Kidney Disease?
(MedPage Today) -- There are six specific clinical variables that can accurately predict rapid decline among patients with autosomal dominant polycystic kidney disease (ADPKD), a researcher reported.
In a study that used real-world data on 1,744... (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - April 8, 2022 Category: Urology & Nephrology Source Type: news
Polyuria, Polydipsia and Possible Diabetes Insipidus?
Discussion
The body is smart. It has mechanisms for maintaining balances within the body in a closely controlled manner but allows for a variety of states. This is very true for fluid balance in the body which is highly controlled between almost all of the major body organ systems. When fluid is low, the sensor sends signals for us to drink, and conserves fluid until we can. When the fluid is high, the kidneys excrete the excess and sends signals not to drink. Usually it works very well. While there are many pathological states that can cause polyuria and/or polydipsia, the most common reason is excessive fluid intake beca...
Source: PediatricEducation.org - March 7, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Mayo Classification by US Useful for Rare Kidney Disease Mayo Classification by US Useful for Rare Kidney Disease
The Mayo classification of autosomal dominant polycystic kidney disease based on ultrasound rather than MRI findings performs well, report clinicians from Spain.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - January 11, 2022 Category: Radiology Tags: Nephrology News Source Type: news
What Are the Advantages and Disadvantages of Different Renal Replacement Therapies?
Discussion
Kidneys are amazing in that they filter the blood, eliminate toxins, balance fluids and electrolytes plus have a lot of reserve to do the job they need to do even when injured. Therefore, depending on the problem, chronic renal disease (CRD) often allows time before renal replacement therapy (RRT) is needed. RRT currently is dialysis (peritoneal or hemodialysis) or renal transplant. In general, the patient’s own kidneys do the best job for them but there is always a balance between the problems of CRD and its management, versus the potentially improved renal function with RRT. RRT itself though has a diffe...
Source: PediatricEducation.org - September 13, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Prolonged Antibiotics Cut Risk of Recurrence in Polycystic Kidney Disease Prolonged Antibiotics Cut Risk of Recurrence in Polycystic Kidney Disease
A prolonged course of antibiotic therapy lasting at least 28 days dramatically reduces the risk of recurrent cyst infection in patients with autosomal dominant polycystic kidney disease.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 11, 2021 Category: Consumer Health News Tags: Nephrology News Source Type: news
Polycystic Kidney Disease (PKD), ARPKD, and ADPKD
Title: Polycystic Kidney Disease (PKD), ARPKD, and ADPKDCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 5/5/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - May 5, 2021 Category: Nutrition Source Type: news
Chemical modification of RNA could play key role in polycystic kidney disease
(UT Southwestern Medical Center) A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the US, UT Southwestern researchers report in a new study. The findings, published online today in Cell Metabolism, suggest new ways to treat this incurable condition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2021 Category: International Medicine & Public Health Source Type: news
How Common are Aortic Aneurysms?
Discussion
Aortic root dilatation or thoracic aortic aneurysm occurs in 6:100,000 individuals > 50 years of age. It is due to aging, hypertension, hypercholesterolemia, and smoking. Tertiary syphilis was a cause in the preantibiotic era.
Pediatric aneurysms are very uncommon but the exact prevalence is different due to the various causes. Aneurysms are due to genetic disorders, congenital anomalies or post-surgical repair. In pediatric patients with sudden cardiac deaths, 5.4% are due to ruptured thoracic aortic aneurysms.
Learning Point
Some causes of pediatric aneurysms include:
Familial thoracic aneurysm and dissect...
Source: PediatricEducation.org - February 22, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Concordia researchers find melatonin is effective against polycystic kidney disease
(Concordia University) Melatonin, a hormone commonly associated with sleep-wake regulation, has been found to reduce cysts in fruit flies, according to Concordia researchers. It's a finding that may affect the way we treat some kidney diseases and reduce the need for kidney transplants. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 26, 2021 Category: International Medicine & Public Health Source Type: news
Removal Plus Transplant Surgery Feasible in Polycystic Kidney Disease
THURSDAY, Oct. 15, 2020 -- Patients with large polycystic kidneys can have their diseased kidneys safely removed laparoscopically at the same time as their kidney transplant (KT) surgery, according to a study published online Sept. 16 in the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 15, 2020 Category: Pharmaceuticals Source Type: news
Pioneering dual surgery a safe option for patients with polycystic kidney disease
(Mayo Clinic) Patients with large polycystic kidneys in need of a kidney transplant can have their diseased kidneys safely removed laparoscopically at the same time as their transplant surgery. That is the finding of a Mayo Clinic study recently published in the American Journal of Transplantation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 29, 2020 Category: International Medicine & Public Health Source Type: news
Reproducing the pathophysiology of polycystic kidney disease from human iPS cells
(Kumamoto University) A joint research project has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. Although cysts derived from renal tubules have been previously documented, this is the first derivation of cysts from collecting ducts, which is more closely related to the pathogenesis of the disease. This research is expected to lead to a better understanding of disease states and the development of new treatment methods. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 21, 2020 Category: Biology Source Type: news
Polycystic Kidney Disease Affect the Kidneys
How Does Polycystic Kidney Disease Affect the Kidneys? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - April 16, 2020 Category: General Medicine Source Type: news
Qualification of Biomarker Total Kidney Volume in Studies for Treatment of Autosomal Dominant Polycystic Kidney Disease Draft Guidance for Industry
Drug Development Tools (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - April 15, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Surgeons remove 'the largest ever KIDNEY' weighing 16lbs from a 56-year-old man in India
Medical staff at the Sir Ganga Ram Hospital in New Delhi, India, removed the giant kidney from a man who was preparing to have a transplant. He has a condition called polycystic kidney disease. (Source: the Mail online | Health)
Source: the Mail online | Health - November 26, 2019 Category: Consumer Health News Source Type: news
