Welsh man's kidneys swell up after being diagnosed with polycystic kidney disease
Rob Thomas, 44, from Pembroke Dock, Wales, was diagnosed with polycystic kidney disease - an illness which causes cysts to develop in the organs - six years ago (Source: the Mail online | Health)
Source: the Mail online | Health - October 4, 2016 Category: Consumer Health News Source Type: news

Polycystic Kidney Disease Tied to Increased Risk for Kidney, Gastric Cancers (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH Adults with polycystic kidneys may have increased risk for multiple cancers, regardless of kidney function, suggests a Lancet Oncology study.Using a Taiwanese health insurance database, researchers … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 21, 2016 Category: Primary Care Source Type: news

Donate a Kidney Now; Get a Voucher for One Later
Howard Broadman, a lawyer and retired judge from California, knows his grandson, Quinn, will probably one day require a kidney transplant. By the time Quinn needs his help, however, Broadman said he may be dead or too old to donate a healthy organ. "I approached UCLA and asked, 'Why don't I give a kidney to someone who needs it now, then get a voucher for my grandson to use when he needs a transplant in the future?' And that's just what we did," Broadman said in a statement. How the program works Broadman worked with Dr. Jeffrey Veale, a transplant surgeon who helped initiate the program at the Ronald Reagan UCLA Medic...
Source: Healthy Living - The Huffington Post - July 19, 2016 Category: Consumer Health News Source Type: news

Virtual tissue technology reveals new drug target in polycystic kidney disease
Using virtual tissue technology, researchers have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA-approved treatment that affects 200,000 people per year in the United States. The study reveals that errors in how cells stick together give rise to two forms of kidney cysts. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 27, 2016 Category: Science Source Type: news

IU study: Virtual tissue technology reveals new drug target in polycystic kidney disease
(Indiana University) Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA-approved treatment that affects 200,000 people per year in the United States. The study, which reveals that errors in how cells stick together give rise to two forms of kidney cysts, appears in the journal Molecular Biology of the Cell. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 27, 2016 Category: Global & Universal Source Type: news

Discovery's Edge: Tackling Polycystic Kidney Disease
The term “teamwork” is widely used when talking about scientific research, but when it comes to the Mayo Clinic version, it means cross-disciplinary teams with complementary members. Some teams form to pursue special problems for limited periods, while others form alliances that last for years, with prolific results. The latter is the case with a [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 2, 2016 Category: Databases & Libraries Source Type: news

Signed, sealed, undelivered: Mechanisms underlying polycystic kidney disease
(Medical University of South Carolina) Zebrafish help investigators at the Medical University of South Carolina shed light on the mechanisms underlying cilia dysfunction in polycystic kidney disease and other ciliopathies (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 17, 2016 Category: Global & Universal Source Type: news

Shaping lumens by force
(National University of Singapore) Scientists from Singapore and France have revealed the underlying mechanism for the formation and growth of a fundamental type of tissue -- epithelial tubes. Defects in the architecture of epithelial tubes lead to diseases such as cholestasis, atherosclerosis and polycystic kidney disease. The study suggests that the shape and size of some types of epithelial tubes are governed by the mechanical forces that arise from the interaction of cells with the supportive extracellular matrix that surrounds them (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 23, 2016 Category: Biology Source Type: news

A diet dividend: Reducing food intake in mice diminishes the growth of their polycystic kidneys
What if polycystic kidney disease (PKD) could be combatted with a strategy as simple as dieting? Such a finding would surely be welcome news to the 12 million people worldwide with the genetic disease. Now researchers say that reducing food intake in mice diminishes the growth of their polycystic kidneys. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 29, 2016 Category: Science Source Type: news

A diet dividend
(University of California - Santa Barbara) Members of the Thomas Weimbs Lab demonstrate that reducing food intake in mice diminishes the growth of their polycystic kidneys (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 28, 2016 Category: Biology Source Type: news

SMC issues positive advice for first ever treatment for ADPKD
JINARC® (tolvaptan) is accepted for use in Scotland for the treatment of autosomal dominant polycystic kidney disease (ADPKD) (Source: Pharmacy Europe)
Source: Pharmacy Europe - January 11, 2016 Category: Drugs & Pharmacology Authors: Annabel De Coster Tags: *** Editor's Pick Practical therapeutics Legislation & regulation Nephrology Patient care adpkd jinarc Latest News smc tolvaptan Source Type: news

When Ayden met Aubrey: Kidney transplant creates a powerful bond between toddlers
Photos by Katherine C. Cohen Theirs is a friendship nurtured by coloring books, built on board games and mad dashes down corridors — but also silently strengthened by nature of a mutual struggle. Three-year-old Ayden Mosher of New York and 2-year-old Aubrey Ferrell of Tennessee met this fall in a lab at Boston Children’s Hospital. It was friendship at first sight. “They were just drawn to each other, and they have been inseparable ever since,” says Aubrey’s mom Janna Ferrell. Aubrey’s story Aubrey was diagnosed with congenital nephrotic syndrome at 4 months old. By 18 months, both kidneys were removed and she ...
Source: Thrive, Children's Hospital Boston - January 7, 2016 Category: Pediatrics Authors: Emily Williams Tags: Diseases & Conditions Our Patients’ Stories kidney kidney transplant Pediatric Transplant Center (PTC) Source Type: news

In their own words: Six families share the impact of organ donation
This is the season for gratitude and giving, a time to celebrate friends, family, the end of one year and the beginning of a new one. But for a select group, it also is a time to celebrate one of the greatest gifts — the gift of life through organ donation. Mickey was born with a unique combination of congenital heart defects and spent most of his early life at Boston Children’s. He was one day shy of 6 months old when he received his heart transplant, and his family is grateful for every day since. “Mickey has shown us what courage and resiliency look like, and his transplant has taught us the true meaning of givin...
Source: Thrive, Children's Hospital Boston - January 5, 2016 Category: Pediatrics Authors: Michelle Higginson Tags: Diseases & Conditions Our Patients’ Stories double lung transplant heart transplant hepatoblastoma kidney transplant Liver transplant multivisceral transplant Pediatric Transplant Center (PTC) Source Type: news

Linking Cancer and Polycystic Kidney Disease
Polycystic kidney disease (PKD) is one of the most common inherited diseases—a parent with PKD has a 50 percent chance of passing the disease on to their child.12/15/2015 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - December 15, 2015 Category: Urology & Nephrology Source Type: news

At ASCB 2015: CRISPR/Cas9 + HPSC = human PKD lab model
(American Society for Cell Biology) By linking up CRISPR/Cas9 with another cutting edge technology, human pluripotent stem cells (hPSCs), Benjamin Freedman, now at the University of Washington, and his colleagues in Joseph Bonventre's lab at Harvard Medical School, have used CRISPR/Cas9 to guide hPSCs into becoming a human cell-based lab model system for polycystic kidney disease (PKD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2015 Category: Global & Universal Source Type: news