Could grapefruit be good for your kidneys?
A natural product found in grapefruit can prevent kidney cysts from forming, new research indicates. Naringenin, which is also present in other citrus fruits, has been found to successfully block the formation of kidney cysts, an effect that occurs in polycystic kidney disease, by regulating the PKD2 protein responsible for the condition. With few treatments currently available, symptoms include high blood pressure and loss of kidney function, and lead to the need for dialysis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 12, 2014 Category: Science Source Type: news
Critical protein discovered for healthy cell growth in mammals
A protein that is required for the growth of tiny, but critical, hair-like structures called cilia on cell surfaces has been discovered. The research has important implications for human health because lack of cilia can lead to serious diseases such as polycystic kidney disease, blindness and neurological disorders. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 27, 2014 Category: Science Source Type: news
Critical protein discovered for healthy cell growth in mammals
(Penn State) A protein that is required for the growth of tiny, but critical, hair-like structures called cilia on cell surfaces has been discovered. The research has important implications for human health because lack of cilia can lead to serious diseases such as polycystic kidney disease, blindness and neurological disorders. A paper describing the research will be published sometime this week in the online early edition of the Proceedings of the National Academy of Sciences. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 27, 2014 Category: Biology Source Type: news
FASEB announces 2014 SRC: Polycystic Kidney Disease -- From Molecular Mechanism to Therapy
(Federation of American Societies for Experimental Biology) This 2014 FASEB Science Research Conference focuses on recent advances in our understanding of the pathogenic mechanisms underlying the cystic renal diseases and the development of therapies to slow down their progression. The polycystic kidney diseases are a group of inherited disorders that result not only in cyst development in the kidney, but also produce a range of extra-renal phenotypic manifestations. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 22, 2014 Category: Biology Source Type: news
European Medicines Agency (EMA) Accepts Otsuka's Marketing Authorisation Application (MAA) for Tolvaptan, an Investigational Compound for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Tolvaptan was discovered by Otsuka in Japan and, if approved by the EMA, would become the first pharmaceutical therapy in Europe for patients with ADPKD
ADPKD is an inherited genetic disease that causes cyst growth in the kidneys, which gradually impair... Biopharmaceuticals, RegulatoryOtsuka Pharmaceutical, ADPKD, tolvaptan, polycystic kidney disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 27, 2013 Category: Pharmaceuticals Source Type: news
Family sets British transplant record with ELEVEN members getting new kidneys as result of genetic condition
A full 11 members of a UK family have received a kidney donation as all suffer a genetic condition called Polycystic Kidney Disease (PKD). (Source: the Mail online | Health)
Source: the Mail online | Health - December 14, 2013 Category: Consumer Health News Source Type: news
Little boy with rare kidney condition can eat chocolate for the first time after getting a donated organ from his father
William Balestrini, three, from Crawley, has autosomal recessive polycystic kidney disease which causes cysts to develop in the kidneys, damaging the tissue. (Source: the Mail online | Health)
Source: the Mail online | Health - December 6, 2013 Category: Consumer Health News Source Type: news
Citrus fruits may prevent kidney cysts
Scientists have discovered that a component found in grapefruit and other citrus fruits may successfully block the development of kidney cysts, according to a study published in the British Journal of Pharmacology. Researchers from the Royal Holloway University, St. George's, the University of London and Kingston University London in the UK, say that the component, called naringenin, could be used to develop new drugs for the treatment of polycystic kidney disease. It is an inherited disorder that causes cysts to develop in the kidneys... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 7, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
Research findings point to new therapeutic approach for common cause of kidney failure
New research has uncovered a process that is defective in patients with autosomal dominant polycystic kidney disease, a common cause of kidney failure. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), point to a new potential strategy for preventing and treating the disease... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 9, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
Somatostatin Analogue Helpful in Polycystic Kidney DiseaseSomatostatin Analogue Helpful in Polycystic Kidney Disease
The somatostatin analogue octreotide long-acting release (LAR) has benefits for patients with autosomal dominant polycystic kidney disease (ADPKD), Italian investigators say. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 3, 2013 Category: Consumer Health News Tags: Nephrology News Source Type: news
FDA Reviewers Pan Tolvaptan Trial Results
WASHINGTON (MedPage Today) -- FDA staff reviewers aren't ready to endorse tolvaptan (Samsca) to treat autosomal dominant polycystic kidney disease, citing missing clinical trial data, they said ahead of an advisory committee meeting to consider the drug. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 2, 2013 Category: Primary Care Source Type: news
In A Mouse Model Of Polycystic Kidney Disease, Vitamin B3 Blocks Cyst Formation
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited systemic disorder caused by mutations in PKD1 or PKD2 that predominately affects the kidneys and is characterized by the formation of cysts in the kidneys and other organs. Xiaogang Li and colleagues at the University of Kansas Medical Centr used a mouse model of ADPKD to explore the role of the protein sirtuin 1 in cyst formation. They found that inhibition of sirtuin 1 activity using vitamin B3 can reduced cyst formation in the kidneys of ADPKD mice... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 19, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
The extra special delivery from the postman who donated his sick colleague a kidney
Ian Shillcott (right), 48, from Weston-super-Mare, needed a transplant because his polycystic kidney disease caused his kidneys to fail. His colleague Charles Czajkowski, 44 (left), offered to be tested - and was found to be a perfect match. (Source: the Mail online | Health)
Source: the Mail online | Health - May 2, 2013 Category: Consumer Health News Source Type: news
Combined Liver-Kidney Transplantation May Benefit Some Patients With Complicated Childhood Polycystic Kidney Disease
A collaborative team of physician-scientists at the Medical College of Wisconsin (MCW) and Children's Hospital of Wisconsin Research Institute has developed a new evidence-based, clinical algorithm to help physicians treat complex patients with autosomal recessive polycystic kidney disease (ARPKD). Their invited manuscript, written by Grzegorz Telega, M.D., associate professor of pediatrics (gastroenterology and hepatology) at MCW and program director of hepatology at Children's Hospital of Wisconsin; David Cronin, II, M.D., Ph.D... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 30, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
New approaches in treating complicated childhood polycystic kidney disease
(Medical College of Wisconsin) A collaborative team of physician-scientists at the Medical College of Wisconsin and Children's Hospital of Wisconsin Research Institute has developed a new evidence-based, clinical algorithm to help physicians treat complex patients with autosomal recessive polycystic kidney disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 26, 2013 Category: Global & Universal Source Type: news
