Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)
CONCLUSIONS: After the history of MIS-C, children in the long-term follow-up had various somatic disorders and disease recurrence. Most patients (64.1%) showed subclinical signs of myocardial involvement within first year of observation. Low expression of CD95 may justify an certain role in the pathogenesis of the disease.PMID:38054683 | DOI:10.23750/abm.v94i6.14788 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - December 6, 2023 Category: General Medicine Authors: Indira Jaxybayeva Riza Boranbayeva Minira Bulegenova Nataliya Urazalieva Valentin Gerein Lyazat Manzhuova Source Type: research
A case of vitiligo after COVID-19 vaccination: a possible role of thymic dysfunction
J Zhejiang Univ Sci B. 2023 Dec 15;24(12):1141-1150. doi: 10.1631/jzus.B2300025.ABSTRACTDuring the coronavirus disease 2019 (COVID-19) pandemic, vaccines help control the spread of infection. To date, 47 vaccines have been approved, with another 227 candidates in various stages of development. In the short period of time since the beginning of their use, evidence has begun to emerge of complications following vaccination in the form of the development or exacerbation of a number of pathological conditions (Block et al., 2022; Haseeb et al., 2022). For example, a population-based study in France identified 1612 cases of myo...
Source: J Zhejiang Univ Sci ... - December 6, 2023 Category: Science Authors: Denis Kuznetsov Oleg Kalyuzhin Andrey Mironov Valery Neschisliaev Anastasiia Kuznetsova Source Type: research
Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)
CONCLUSIONS: After the history of MIS-C, children in the long-term follow-up had various somatic disorders and disease recurrence. Most patients (64.1%) showed subclinical signs of myocardial involvement within first year of observation. Low expression of CD95 may justify an certain role in the pathogenesis of the disease.PMID:38054683 | DOI:10.23750/abm.v94i6.14788 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - December 6, 2023 Category: General Medicine Authors: Indira Jaxybayeva Riza Boranbayeva Minira Bulegenova Nataliya Urazalieva Valentin Gerein Lyazat Manzhuova Source Type: research
Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)
CONCLUSIONS: After the history of MIS-C, children in the long-term follow-up had various somatic disorders and disease recurrence. Most patients (64.1%) showed subclinical signs of myocardial involvement within first year of observation. Low expression of CD95 may justify an certain role in the pathogenesis of the disease.PMID:38054683 | DOI:10.23750/abm.v94i6.14788 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - December 6, 2023 Category: General Medicine Authors: Indira Jaxybayeva Riza Boranbayeva Minira Bulegenova Nataliya Urazalieva Valentin Gerein Lyazat Manzhuova Source Type: research
Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)
CONCLUSIONS: After the history of MIS-C, children in the long-term follow-up had various somatic disorders and disease recurrence. Most patients (64.1%) showed subclinical signs of myocardial involvement within first year of observation. Low expression of CD95 may justify an certain role in the pathogenesis of the disease.PMID:38054683 | DOI:10.23750/abm.v94i6.14788 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - December 6, 2023 Category: General Medicine Authors: Indira Jaxybayeva Riza Boranbayeva Minira Bulegenova Nataliya Urazalieva Valentin Gerein Lyazat Manzhuova Source Type: research
Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)
CONCLUSIONS: After the history of MIS-C, children in the long-term follow-up had various somatic disorders and disease recurrence. Most patients (64.1%) showed subclinical signs of myocardial involvement within first year of observation. Low expression of CD95 may justify an certain role in the pathogenesis of the disease.PMID:38054683 | DOI:10.23750/abm.v94i6.14788 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - December 6, 2023 Category: General Medicine Authors: Indira Jaxybayeva Riza Boranbayeva Minira Bulegenova Nataliya Urazalieva Valentin Gerein Lyazat Manzhuova Source Type: research
Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)
CONCLUSIONS: After the history of MIS-C, children in the long-term follow-up had various somatic disorders and disease recurrence. Most patients (64.1%) showed subclinical signs of myocardial involvement within first year of observation. Low expression of CD95 may justify an certain role in the pathogenesis of the disease.PMID:38054683 | DOI:10.23750/abm.v94i6.14788 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - December 6, 2023 Category: General Medicine Authors: Indira Jaxybayeva Riza Boranbayeva Minira Bulegenova Nataliya Urazalieva Valentin Gerein Lyazat Manzhuova Source Type: research
Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)
CONCLUSIONS: After the history of MIS-C, children in the long-term follow-up had various somatic disorders and disease recurrence. Most patients (64.1%) showed subclinical signs of myocardial involvement within first year of observation. Low expression of CD95 may justify an certain role in the pathogenesis of the disease.PMID:38054683 | PMC:PMC10734220 | DOI:10.23750/abm.v94i6.14788 (Source: Acta Bio-Medica : Atenei Parmensis)
Source: Acta Bio-Medica : Atenei Parmensis - December 6, 2023 Category: General Medicine Authors: Indira Jaxybayeva Riza Boranbayeva Minira Bulegenova Nataliya Urazalieva Valentin Gerein Lyazat Manzhuova Source Type: research
Mulibrey nanism and immunological complications: a comprehensive case report and literature review
We present a case of MUL with progressive lymphopenia and review similar cases from the literature.ResultsOur patient presented with prenatal onset growth restriction, characteristic dysmorphic features, and Wilms’ tumor. She developed progressive lymphopenia starting at 10 years of age, leading to the initiation of intravenous immunoglobulin (IVIG) replacement therapy and infection prophylaxis. Genetic analysis detected a likely pathogenic variant on the maternal allele and copy number loss on the paternal allele in TRIM37. Subsequently a cardiac magnetic resonance imaging was conducted revealing signs of pericardial co...
Source: Frontiers in Immunology - December 5, 2023 Category: Allergy & Immunology Source Type: research
Immune Checkpoint Inhibitors and Their Cardiovascular Adverse Effects
Oncol Rev. 2023 Nov 17;17:11456. doi: 10.3389/or.2023.11456. eCollection 2023.ABSTRACTImmune checkpoint inhibitors (ICIs) have reshaped and have become a well-established treatment modality for multiple advanced-stage malignancies. ICIs block the immune system regulatory checkpoints, namely CTLA-4 and PD-1/PDL1, which provokes excess immune response against self-antigens. Immune modulation with ICIs can result in diverse immune-related adverse events targeting organ systems. Several cases of ICI-related cardiotoxicity were reported, while the actual incidence was likely underestimated due to heterogeneous clinical presenta...
Source: Atherosclerosis - December 4, 2023 Category: Cardiology Authors: Ravi Kumar Paluri Yochitha Pulipati Dileep Kumar Reddy Regalla Source Type: research
Immune Checkpoint Inhibitors and Their Cardiovascular Adverse Effects
Oncol Rev. 2023 Nov 17;17:11456. doi: 10.3389/or.2023.11456. eCollection 2023.ABSTRACTImmune checkpoint inhibitors (ICIs) have reshaped and have become a well-established treatment modality for multiple advanced-stage malignancies. ICIs block the immune system regulatory checkpoints, namely CTLA-4 and PD-1/PDL1, which provokes excess immune response against self-antigens. Immune modulation with ICIs can result in diverse immune-related adverse events targeting organ systems. Several cases of ICI-related cardiotoxicity were reported, while the actual incidence was likely underestimated due to heterogeneous clinical presenta...
Source: Atherosclerosis - December 4, 2023 Category: Cardiology Authors: Ravi Kumar Paluri Yochitha Pulipati Dileep Kumar Reddy Regalla Source Type: research
Cardiovascular Manifestations in Inflammatory Bowel Disease
Curr Cardiol Rev. 2023 Nov 24. doi: 10.2174/011573403X256094231031074753. Online ahead of print.ABSTRACTInflammatory bowel disease is a group of long-term systemic inflammatory disorders affecting the gastrointestinal tract, including Crohn's disease and ulcerative colitis, which may be associated with an increased risk of developing extraintestinal manifestations, including cardiovascular disease, thereby decreasing the quality of life. Pathophysiological changes associated with inflammatory bowel disease include alterations of the microbiome, endotoxemia, and changes to glucose and lipid metabolism. Inflammatory bowel di...
Source: Current Cardiology Reviews - November 29, 2023 Category: Cardiology Authors: Anish Meda Fremita Fredrick Urvashi Rathod Priyanshi Shah Rohit Jain Source Type: research
