Difficult echocardiogram after pericardiocentesis
Clinical introduction A patient in their 70s, a heavy smoker with low body max index (17 kg/m2) already known for previous relapses of pericarditis on echocardiographic follow-up, was admitted for worsening pericardial effusion (figure 1A,B; ). Given initial signs of cardiac tamponade, the patient underwent urgent pericardiocentesis (subxiphoid approach) with drainage of 1500 cc of pericardial fluid, without evident complications. The pericardial catheter was kept in place for 48 hours until complete resolution of the effusion, and then carefully removed. The next-day echocardiogram was made difficult by the presence in mu...
Source: Heart - November 27, 2023 Category: Cardiology Authors: Mapelli, M., Balata, F., Lucci, C. Tags: Image challenges Source Type: research

R égurgitation mitrale sévère due à la sarcoïdose cardiaque : une présentation clinique inhabituelle ; une étude de cas et des recherches antérieures
This article describes a case of a patient with a history of pulmonary sarcoidosis who presented with congestive heart failure, on the basis of severe mitral regurgitation secondary to cardiac infiltration and summarizes the published evidence regarding CS and mitral regurgitation.PMID:37988891 | DOI:10.1016/j.ancard.2023.101675 (Source: Annales de Cardiologie et d'Angeiologie)
Source: Annales de Cardiologie et d'Angeiologie - November 21, 2023 Category: Cardiology Authors: Dimitrios Polyzos Georgios Patavoukas Anastasios Lykoudis Maria Mamaloukaki Konstantinos Lampropoulos Source Type: research

R égurgitation mitrale sévère due à la sarcoïdose cardiaque : une présentation clinique inhabituelle ; une étude de cas et des recherches antérieures
This article describes a case of a patient with a history of pulmonary sarcoidosis who presented with congestive heart failure, on the basis of severe mitral regurgitation secondary to cardiac infiltration and summarizes the published evidence regarding CS and mitral regurgitation.PMID:37988891 | DOI:10.1016/j.ancard.2023.101675 (Source: Annales de Cardiologie et d'Angeiologie)
Source: Annales de Cardiologie et d'Angeiologie - November 21, 2023 Category: Cardiology Authors: Dimitrios Polyzos Georgios Patavoukas Anastasios Lykoudis Maria Mamaloukaki Konstantinos Lampropoulos Source Type: research

The Association Between Aspirin Use and Immune-Related Adverse Events in Specific Cancer Patients Receiving ICIs Therapy: Analysis of the FAERS Database
This study analyzed adverse reaction data associated with the use of ICIs in the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database, from the approval date of each drug until October 1, 2022. Multivariate logistic regression was employed to assess the association of aspirin use with irAEs in patients receiving ICIs.The results indicated that aspirin use was associated with an increased risk of irAEs in a pan-cancer analysis, with a more pronounced association in specific cancer types such as lung cancer, mesothelioma, and pancreatic cancer. However, in lymphoma, aspirin use was associated...
Source: Frontiers in Pharmacology - November 15, 2023 Category: Drugs & Pharmacology Source Type: research

Drug-induced cardiac toxicity and adverse drug reactions, a narrative review
Therapie. 2023 Oct 31:S0040-5957(23)00169-5. doi: 10.1016/j.therap.2023.10.008. Online ahead of print.ABSTRACTDrug-induced cardiotoxicity is a primary concern in both drug development and clinical practice. Although the heart is not a common target for adverse drug reactions, some drugs still cause various adverse cardiac events, with sometimes severe consequences. Direct cardiac toxicity encompasses functional and structural changes of the cardiovascular system due to possible exposure to medicines. This phenomenon extends beyond cardiovascular drugs to include non-cardiovascular drugs including anticancer drugs such as t...
Source: Therapie - November 13, 2023 Category: Psychiatry & Psychology Authors: Alexandre Destere Diane Merino Thibaud Lavrut Fanny Rocher Delphine Viard Milou-Daniel Drici Alexandre O G érard Source Type: research