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Enzyme inhibitory activities of phenolic compounds in pecan and the effect on starch digestion
The objective of this study was to investigate the enzyme inhibitory activities of pecan phenolic compounds (PPC) and the effect in starch hydrolysis by in vitro simulation digestion. PPC was extracted with a solvent mixture from pecan powder and freeze-dried. PPC was tested for the inhibitory effects on α-amylase and α-glucosidase via enzyme kinetics study. Static in vitro digestion trials were conducted to evaluate the effect of intake of PPC and pecan powder on starch digestion. The PPC displayed a potent inhibition effect against α-amylase and α-glucosidase with IC50 of 77.9 μg/mL and 9.02 μg/mL, respectively. Bo...
Source: International Journal of Biological Macromolecules - August 13, 2022 Category: Biochemistry Authors: Jiannan Feng Fanbin Kong Source Type: research

Quantitative In Silico Evaluation of Allergenic Proteins from Anacardium occidentale , Carya illinoinensis , Juglans regia and Pistacia vera and Their Epitopes as Precursors of Bioactive Peptides
Curr Issues Mol Biol. 2022 Jul 6;44(7):3100-3117. doi: 10.3390/cimb44070214.ABSTRACTThe aim of the study presented here was to determine if there is a correlation between the presence of specific protein domains within tree nut allergens or tree nut allergen epitopes and the frequency of bioactive fragments and the predicted susceptibility to enzymatic digestion in allergenic proteins from tree nuts of cashew (Anacardium occidentale), pecan (Carya illinoinensis), English walnut (Juglans regia) and pistachio (Pistacia vera) plants. These bioactive peptides are distributed along the length of the protein and are not enriched...
Source: Current Issues in Molecular Biology - July 25, 2022 Category: Molecular Biology Authors: Piotr Minkiewicz Christopher P Mattison Ma łgorzata Darewicz Source Type: research

The Terrestrial Biosphere Model Farm
J Adv Model Earth Syst. 2022 Feb;14(2):e2021MS002676. doi: 10.1029/2021MS002676. Epub 2022 Feb 16.ABSTRACTModel Intercomparison Projects (MIPs) are fundamental to our understanding of how the land surface responds to changes in climate. However, MIPs are challenging to conduct, requiring the organization of multiple, decentralized modeling teams throughout the world running common protocols. We explored centralizing these models on a single supercomputing system. We ran nine offline terrestrial biosphere models through the Terrestrial Biosphere Model Farm: CABLE, CENTURY, HyLand, ISAM, JULES, LPJ-GUESS, ORCHIDEE, SiB-3, an...
Source: Adv Data - July 21, 2022 Category: Epidemiology Authors: Joshua B Fisher Munish Sikka Gary L Block Christopher R Schwalm Nicholas C Parazoo Hannah R Kolus Malen Sok Audrey Wang Anna Gagne-Landmann Shakirudeen Lawal Alexandre Guillaume Alyssa Poletti Kevin M Schaefer Bassil El Masri Peter E Levy Yaxing Wei Micha Source Type: research

Molecules, Vol. 27, Pages 4326: The Content of Phenolic Compounds and Mineral Elements in Edible Nuts
zak Edible nuts are an important component of a healthy diet, and their frequent consumption has beneficial impact on human health, including reducing the risk of cardiovascular and neurodegenerative diseases. Moreover, various factors, including cultivar, climate, soil characteristic, storage and treatment have influence on the chemical composition of nuts. Therefore, nine tree nut types and peanuts commonly available on Polish market were evaluated for phenolic profile and mineral elements content. The concentration of individual phenolic compounds, including flavonoids, aromatic acids and caffeic acid phenethyl este...
Source: Molecules - July 6, 2022 Category: Chemistry Authors: Magdalena Wo źniak Agnieszka Wa śkiewicz Izabela Ratajczak Tags: Article Source Type: research

Genes, Vol. 13, Pages 1103: Genome-Wide Analysis of the GDSL Genes in Pecan (Carya illinoensis K. Koch): Phylogeny, Structure, Promoter Cis-Elements, Co-Expression Networks, and Response to Salt Stresses
In this study, 87 CilGDSLs were identified and divided into 2 groups and 12 subgroups using phylogenetic analysis; members of the same sub-branch had conserved gene structure and motif composition. The majority of the genes had four introns and were composed of an &alpha;-helix and a &beta;-strand. Subcellular localization analysis revealed that these genes were localized in the extracellular matrix, chloroplasts, cytoplasm, nucleus, vacuole, and endoplasmic reticulum, and were validated by transient expression in tobacco mesophyll cells. Furthermore, the analysis of the promoter cis-elements for the CilGDS...
Source: Genes - June 21, 2022 Category: Genetics & Stem Cells Authors: Yun Jiao Jianhong Zhang Cunde Pan Tags: Article Source Type: research

Comparative Analysis of the Transcriptomes of Persisting and Abscised Fruitlets: Insights into Plant Hormone and Carbohydrate Metabolism Regulated Self-Thinning of Pecan Fruitlets during the Early Stage
In this study, we conducted transcriptomic profiling of persisting and abscised fruitlets in early fruit development by RNA-seq. A total of 11,976 differentially expressed genes (DEGs) were identified, 3012 upregulated and 8964 downregulated, in a comparison of abscised vs. persisting fruitlets at 35 days after anthesis (DAA). Our transcriptomic data suggest that gene subsets encoding elements involving the biosynthesis, metabolism, perception, signal transduction, and crosstalk of the plant hormones abscisic acid (ABA), auxin, cytokinin, ethylene, and gibberellin (GA) and plant growth regulators jasmonates, salicylic acid...
Source: Current Issues in Molecular Biology - June 20, 2022 Category: Molecular Biology Authors: Jiyu Zhang Tao Wang Fan Zhang Yongzhi Liu Gang Wang Source Type: research

Synergistic Interactions between Tocol and Phenolic Extracts from Different Tree Nut Species against Human Cancer Cell Lines
Molecules. 2022 May 14;27(10):3154. doi: 10.3390/molecules27103154.ABSTRACTTree nuts are rich in polar (phenolic compounds) and non-polar (tocols) antioxidants, with recognized effects in the prevention of diseases such as cancer. These biomolecules possess antiproliferative activity on cancer cells; however, the combined effect of both types of compounds has been scarcely studied, and this approach could give valuable information on the real anticancer potential of tree nuts. In the present study, the antiproliferative activity of pure tocols and phenolic compounds, tocol- and phenolic-rich extracts (TRE and PRE, respecti...
Source: Cancer Control - May 28, 2022 Category: Cancer & Oncology Authors: Jazm ín C Stevens-Barrón Abraham Wall-Medrano Emilio Álvarez-Parrilla Imelda Olivas-Armend áriz Humberto Astiazaran-Garc ía Ram ón E Robles-Zepeda Laura A De la Rosa Source Type: research

Molecules, Vol. 27, Pages 3154: Synergistic Interactions between Tocol and Phenolic Extracts from Different Tree Nut Species against Human Cancer Cell Lines
e la Rosa Tree nuts are rich in polar (phenolic compounds) and non-polar (tocols) antioxidants, with recognized effects in the prevention of diseases such as cancer. These biomolecules possess antiproliferative activity on cancer cells; however, the combined effect of both types of compounds has been scarcely studied, and this approach could give valuable information on the real anticancer potential of tree nuts. In the present study, the antiproliferative activity of pure tocols and phenolic compounds, tocol- and phenolic-rich extracts (TRE and PRE, respectively) from tree nuts and the extracts combinations, was evalu...
Source: Molecules - May 14, 2022 Category: Chemistry Authors: Jazm ín C. Stevens-Barrón Abraham Wall-Medrano Emilio Álvarez-Parrilla Imelda Olivas-Armend áriz Humberto Astiazaran-Garc ía Ram ón E. Robles-Zepeda Laura A. De la Rosa Tags: Article Source Type: research

Insight into the CBL and CIPK gene families in pecan (Carya illinoinensis): identification, evolution and expression patterns in drought response
Calcium (Ca2+) serves as a ubiquitous second messenger and plays a pivotal role in signal transduction. Calcineurin B-like proteins (CBLs) are plant-specific Ca2+ sensors that interact with CBL-interacting protei... (Source: BMC Plant Biology)
Source: BMC Plant Biology - April 28, 2022 Category: Biology Authors: Kaikai Zhu, Pinghua Fan, Hui Liu, Pengpeng Tan, Wenjuan Ma, Zhenghai Mo, Juan Zhao, Guolin Chu and Fangren Peng Tags: Research Source Type: research