Upper digestive bleeding secondary to duodenal infiltration due to pancreatic cancer: a therapeutic challenge
Rev Esp Enferm Dig. 2023 Jun;115(6):346. doi: 10.17235/reed.2023.9738/2023.ABSTRACTA 68-year-old woman with stage IV pancreatic adenocarcinoma (liver and lymph node metastases) on first-line treatment with gemcitabine. As a non-oncological comorbidity, the patient was anticoagulated with enoxaparin 8000 IU/24 hours because she had a mitral valve prosthesis. The patient made a medical consultation for presenting vomits which looked like coffee grounds and melaena. In the complete blood count, a hemoglobin of 7.5 g/dL was detected. Transfusion support, pantoprazole infusion (80 mg in 500 cc of 0.9% SSF every 12 hours) and pa...
Source: Revista Espanola de Enfermedades Digestivas - May 26, 2023 Category: Gastroenterology Authors: Jos é García Flores Manuel S ánchez Cánovas Emilio Torrella Cort és Source Type: research

Efficacy and safety of proton pump inhibitors and H2 receptor antagonists in the initial non ‑eradication treatment of duodenal ulcer: A network meta‑analysis
In conclusion, pantoprazole (40 mg once daily) was the best choice for the initial non-eradication treatment of patients with duodenal ulcer, and cimetidine (400 mg twice daily), omeprazole (20 mg once daily), lansoprazole (15 mg once daily), ilaprazole (5 mg once daily) and rabeprazole (10 mg once daily) could be used as the first choice. If the aforementioned pharmaceuticals cannot be prescribed, famotidine (40 mg twice daily) is recommended.PMID:37206569 | PMC:PMC10189747 | DOI:10.3892/etm.2023.11971 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - May 19, 2023 Category: General Medicine Authors: Xiangbo Meng Xiuying Zhu Baixue Li Jibin Liu Jiawei Zhao Hua Wang Quansheng Feng Yue Su Source Type: research