Helicobacter Pylori Eradication in Functional Dyspepsia
Conditions:   Dyspepsia;   Helicobacter Pylori Infection Interventions:   Drug: Clarithromycin 500 mg twice a day, Amoxicillin 1000mg twice a day and Pantoprazole 40mg twice a day for two weeks, followed by six more weeks of Pantoprazole 40mg once daily;   Drug: Proton pump inhibitors (Pantoprazole 40 mg or equivalent) for eight weeks and prokinetics before meals (Le vosulpiride 25mg, Acotiamide 100mg, Itopride 50mg) as when required. Sponsor:   Sir Ganga Ram Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 6, 2021 Category: Research Source Type: clinical trials

Comparing the Efficacy of 10-day Reverse Hybrid Therapy and 10-day Triple Therapy Plus Bismuth Therapy.
Condition:   Helicobacter Pylori Infection Interventions:   Drug: (panto+amox+clar+metr)+(panto+amox);   Drug: pantoprazole+bismuth+amox+clar Sponsor:   Kaohsiung Veterans General Hospital. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 28, 2020 Category: Research Source Type: clinical trials

Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19): A structured summary of a study protocol for a randomised controlled trial
AbstractObjectivesPrimary objective: Evaluation of the effect of the proton pump inhibitor (PPI) pantoprazole on the absorption of hydroxychloroquine (HCQ).Secondary objectives:• Evaluation of the relationship between HCQ concentrations in whole blood, plasma and intracellular concentrations in target cells - peripheral blood mononuclear cells (PBMCs).• Evaluation of HCQ as a potential perpetrator in drug-drug interactions at the level of cytochrome P450 (CYP) 3A4 and CYP2D6 (major drug metabolizing enzymes).Trial designSingle centre, open-label, parallel group, two-arm, phase I drug-drug interaction trial.Partic...
Source: Trials - June 28, 2020 Category: Research Source Type: clinical trials

Effect of Obesity on Proton Pump Inhibitors
Conditions:   Pediatric Obesity;   NAFLD;   GERD Intervention:   Drug: Pantoprazole Sponsor:   Children's Mercy Hospital Kansas City Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 30, 2020 Category: Research Source Type: clinical trials

Pantoprazole in Cisplatin Nephrotoxicity
Condition:   Oncology Interventions:   Drug: Pantoprazole low dose;   Drug: Pantoprazole high dose;   Other: Standard hydration;   Drug: Cisplatin Sponsor:   Sherief Abd-Elsalam Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2020 Category: Research Source Type: clinical trials

Efficacy of DA-5204 on Gastroesophageal Reflux Disease
Condition:   Esophageal Disease Interventions:   Drug: Pantoprazole;   Drug: DA-5204;   Drug: Placebo Sponsors:   Seoul National University Hospital;   Dong-A ST Co., Ltd. Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 26, 2019 Category: Research Source Type: clinical trials